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Characterization and Clinical Management of Dilated Cardiomyopathy
| Characterization and Clinical Management of Dilated Cardiomyopathy |
| Autore | Merlo Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (232 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
SCN5A
cardiac sodium channel cardiac channelopathy dilated cardiomyopathy precision medicine arrhythmias atrial fibrillation cardiomyopathy heart failure supraventricular arrhythmia systolic dysfunction tachycardiomyopathy ventricular arrhythmia left atrial strain cardiac resynchronization therapy muscular dystrophy calcium heart gene therapy phospholamban Serca2a mdx oxidative stress membrane stabilization left ventricular noncompaction congenital heart disease congestive heart failure non-ischemic cardiomyopathy genetics desmin mitochondrial dysfunction myopathy whole exome sequencing laminopathy LMNA biomarkers troponin T NT-proBNP malignant ventricular arrhythmia arrhythmic risk stratification DNA methylation alternative splicing epigenetics nonischemic dilated cardiomyopathy cardiac magnetic resonance imaging late gadolinium enhancement long axis strain left ventricle sphericity index major adverse cardiovascular events sex differences left ventricular reverse remodelling long-term outcomes left ventricle non-compaction cardiomyopathy cardiac magnetic resonance titin RNA binding motif protein 20 (RBM20) sarcomere diastolic dysfunction phosphorylation non-sense mRNA decay mammalian target of rapamycin (mTOR) complex-1 duchenne muscular distrophy |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557595503321 |
Merlo Marco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Creatine Supplementation for Health and Clinical Diseases
| Creatine Supplementation for Health and Clinical Diseases |
| Autore | Kreider Richard B |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (562 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
ergogenic aids
cellular metabolism phosphagens sarcopenia cognition diabetes creatine synthesis deficiencies concussion traumatic brain injury spinal cord injury muscle atrophy rehabilitation pregnancy immunity anti-inflammatory antioxidant anticancer creatine nutritional supplements fertility newborn development brain injury post-viral fatigue syndrome chronic fatigue syndrome GAA creatine kinase dietary supplements exercise skeletal muscle glycemic control type 2 diabetes mellitus phosphorylcreatine dietary supplement ergogenic aid youth athletes osteoporosis osteosarcopenia frailty cachexia innate immunity adaptive immunity inflammation macrophage polarization cytotoxic T cells toll-like receptors vascular pathology cardiovascular disease oxidative stress vascular health female menstrual cycle hormones exercise performance menopause mood children height BMI-for-age stature-for-age growth phosphocreatine creatine transporter supplementation treatment heart heart failure ischemia myocardial infarction anthracycline cardiac toxicity energy metabolism cell survival bioinformatics systems biology cellular allostasis dynamic biosensor pleiotropic effects of creatine (Cr) supplementation inflammatory bowel diseases (IBD) ulcerative colitis Crohn’s disease creatine kinase (CK) phosphocreatine (PCr) creatine transporter (CrT) intestinal epithelial cell protection intestinal tissue protection creatine perfusion organ transplantation Adenosine mono-phosphate (AMP) activated protein kinase (AMPK) liver kinase B1 (LKB1) mitochondrial permeability transition pore (mPTP) reactive oxygen species (ROS) glucose transporter (GLUT) T cell antitumor immunity metabolic regulator cancer immunotherapy supplements muscle damage recovery immobilization atrophy muscular dystrophy amyotrophic lateral sclerosis Parkinson’s Disease cardiopulmonary disease mitochondrial cytopathy hypertrophy athletic performance weightlifting resistance exercise training muscular power muscular adaptation muscle fatigue adipose tissue muscle strength physiological adaptation mitochondria thermogenesis MAP kinase signaling system sodium-chloride-dependent neurotransmitter symporters signal transduction intradialytic creatine supplementation hemodialysis muscle protein energy wasting clinical trial muscle weakness chronic fatigue cognitive impairment depression anemia resistance training sports nutrition strength toxicity methylation hyperhomocysteinemia neuromodulation MCDA mitochondriopathia cardiac infarction long COVID hypoxia stroke neurodegenerative diseases noncommunicable disease adenosine 5′-monopnophosphate-activated protein kinase anthracyclines creatine supplementation cardiac signaling cardiotoxicity doxorubicin soy vegetarian/vegan diet amino acids dietary ingredients performance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566476003321 |
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Kreider Richard B
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Genome Editing in Neurosciences [[electronic resource] /] / edited by Rudolf Jaenisch, Feng Zhang, Fred Gage
| Genome Editing in Neurosciences [[electronic resource] /] / edited by Rudolf Jaenisch, Feng Zhang, Fred Gage |
| Autore | Feng Zhang |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Springer Nature, 2017 |
| Descrizione fisica | 1 online resource (XI, 123 p. 16 illus. in color.) |
| Disciplina |
611.01816
599.935 |
| Collana | Research and Perspectives in Neurosciences |
| Soggetto topico |
Human genetics
Neurosciences Biomedical engineering Human Genetics Biomedical Engineering/Biotechnology |
| Soggetto non controllato |
CRISPR
muscular dystrophy Parkinson's disease DNA Rett syndrome double-strand breaks Huntington's disease genetic engineering |
| ISBN | 3-319-60192-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- In vitro modeling of complex neurological diseases -- Aquatic model organisms in neurosciences : the genome editing revolution -- Genome-wide genetic screening in the mammalian CNS -- CRISPR/Cas9-mediated Knockin and Knockout in Zebrafish -- Dissecting the role of synaptic proteins with CRISPR -- Recurrently Breaking Genes in Neural Progenitors: Potential Roles of DNA Breaks in Neuronal Function, Degeneration and Cancer -- Neuroscience research using non-human primate models and genome editing -- Multiscale genome engineering: Genome-wide screens and targeted approaches -- Using Genome Engineering to Understand Huntington’s Disease -- Therapeutic gene editing in muscles and muscle stem cells. |
| Record Nr. | UNINA-9910231247003321 |
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Feng Zhang
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| Springer Nature, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Muscle Homeostasis and Regeneration : From Molecular Mechanisms to Therapeutic Opportunities
| Muscle Homeostasis and Regeneration : From Molecular Mechanisms to Therapeutic Opportunities |
| Autore | Musarò Antonio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (500 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
lysine
mTORC1 satellite cells proliferation skeletal muscle growth muscle satellite cell transthyretin thyroid hormone myogenesis exosomes skeletal muscle genotype genetic variation muscle phenotypes sarcopenia aging calcium homeostasis hibernation mitochondria sarcoplasmic reticulum Acvr1b Tgfbr1 myostatin Col1a1 fibrosis atrophy IGF2R muscle homeostasis inflammation muscular dystrophy pericytes macrophages Nfix phagocytosis RhoA-ROCK1 splicing isoforms CRISPR-Cas9 exon deletion NF-Y muscle differentiation C2C12 cells denervation neuromuscular junction heavy resistance exercise acetylcholine receptor cell culture neonatal myosin neural cell adhesion molecule biomarkers mitophagy mitochondrial dynamics mitochondrial quality control mitochondrial-derived vesicles (MDVs) mitochondrial-lysosomal axis Hibernation electron microscopy immunocytochemistry α-smooth muscle actin confocal microscopy connexin 43 connexin 26 gap junctions myofibroblasts Platelet-Rich Plasma transforming growth factor (TGF)-β1 muscle regeneration inflammatory response cell precursors experimental methods stem cell markers muscles heterotopic ossification skeletal muscle stem and progenitor cells HO precursors muscle atrophy septicemia mitochondrial fusion mitochondrial fission iPSC extracellular vesicles Drosophila muscle genetic control muscle diversification fascicle myofiber myofibril sarcomere hypertrophy hyperplasia splitting radial growth longitudinal growth exercise muscle stem cells stem cells niche neuromuscular disorders Duchenne muscular dystrophy pharmacological approach single-cell mass cytometry skeletal muscle regeneration skeletal muscle homeostasis fibro/adipogenic progenitors myogenic progenitors muscle populations evolution metazoans differentiation transdifferentiation muscle precursors regenerative medicine stem cells FAPs tissue niche growth factors muscle pathology |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Muscle Homeostasis and Regeneration |
| Record Nr. | UNINA-9910557587003321 |
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Musarò Antonio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy: A Translational Approach
| Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy: A Translational Approach |
| Autore | Paolo Bonaldo |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
Aging sarcopenia
muscular dystrophy Mitochondrial dysfunction therapy skeletal muscle Autophagy Animal Models Apoptosis satellite cells muscle imaging |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy |
| Record Nr. | UNINA-9910136802403321 |
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Paolo Bonaldo
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| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Developments in Annexin Biology
| Recent Developments in Annexin Biology |
| Autore | Jaiswal Jyoti K |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (266 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
inflammation
nigericin pyroptosis mass spectrometry lipidomics anxA2 Birbeck granules Langerhans cell A2t annexin plasma membrane repair membrane curvature membrane curvature sensing membrane shaping interdisciplinary research cell rupture membrane damage bias analysis G protein-coupled receptor (GPCR) formyl peptide receptor 1 danger-associated molecular pattern (DAMP) pathogen-associated molecular pattern (PAMP) annexin A1 peptide Ac2-26 cholesterol AnxA6 chaperone-mediated autophagy endolysosomes NPC1 Lamp2A annexin A2 microdomain cross-linker quartz crystal microbalance with dissipation monitoring (QCM-D) mucin-1 claudin-1 zona occludens ERK1/2 pathway angiogenesis F-actin polymerization BeWo spheroids Ishikawa cells influenza RNA-sequencing transcriptomics autophagy Annexin-A1 infection adherens junction macroautophagy breast cancer estrogen receptor negative Annexin A2 metastasis annexin-A6 membrane repair human skeletal muscle cap subdomain fluorescence electron microscopy CLEM annexin A6 RasGRF2 EGFR cell growth cell motility acquired resistance tyrosine kinase inhibitors muscle injury plasma membrane vesicle muscular dystrophy annexinA2 egress exocytosis chromaffin cells thrombosis Annexin A1 formyl peptide receptors sickle cell disease sepsis Annexin membrane injury virus lipid cancer |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557351303321 |
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Jaiswal Jyoti K
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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