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Drug Repositioning: Current Advances and Future Perspectives
Drug Repositioning: Current Advances and Future Perspectives
Autore Yuhei Nishimura
Pubbl/distr/stampa Frontiers Media SA, 2019
Descrizione fisica 1 electronic resource (153 p.)
Collana Frontiers Research Topics
Soggetto non controllato database
Integrative strategies
molecular docking
polypharmacology
multi-omics
computational analysis
Drug Repositioning
data sharing
Patenting
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti Drug Repositioning
Record Nr. UNINA-9910346734903321
Yuhei Nishimura  
Frontiers Media SA, 2019
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Identification and Characterization of Genetic Components in Autism Spectrum Disorders 2019
Identification and Characterization of Genetic Components in Autism Spectrum Disorders 2019
Autore Butler Merlin G
Pubbl/distr/stampa Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
Descrizione fisica 1 electronic resource (256 p.)
Soggetto topico Research & information: general
Biology, life sciences
Genetics (non-medical)
Soggetto non controllato autism spectrum disorders (ASD)
cancer
overlapping genes and gene profiling
super-pathways
phenotypes and diseases
molecular functions and processes
15q11.2 BP1-BP2 microdeletion (Burnside-Butler) syndrome
imprinting
parent-of-origin effects
phenotype-genotype correlation
autism
developmental delays
motor delays
microbiome
gut
ProSAP2
Phelan McDermid Syndrome
gut–brain interaction
leaky gut
IL-6
SHANK
collapsin response mediator protein 4
autism spectrum disorder
neurodevelopmental disorder
whole-exome sequencing
animal model
sex different phenotypes
15q11.2 BP1–BP2 microdeletion (Burnside–Butler syndrome)
NIPA1
NIPA2
CYFIP1
TUBGCP5 genes
Prader–Willi and Angelman syndromes
magnesium transporters and supplementation
potential treatment options
intellectual disability
AMPA receptors
NMDA receptors
guanine nucleotide exchange factor
synaptic plasticity
Autism spectrum disorder
ASD
Obesity
Overweight
Body mass index
BMI
autism candidate genes
synaptotagmin-like protein 4 (SYTL4)
transmembrane protein 187 (TMEM187)
SYTL4-protein structure
STRING-protein-protein interaction
expression profile
microRNA- interactions
autism spectrum disorders
biological networks
genomics
multi-omics
network diffusion
data integration
genetics
quantitative traits
stratification by trait severity
heterogeneity reduction
case-control association analysis
fragile X syndrome
RNA toxicity
DNA methylation
mosaicism
pediatrics
MS-QMA
AmplideX
cytokine
monocyte
β-glucan
T cell cytokine
trained immunity
maternal immune activation
epigenetics
mice
postnatal VPA injection
SAM
gene expression
nanostring
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910566483203321
Butler Merlin G  
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Integration of Multisource Heterogenous Omics Information in Cancer
Integration of Multisource Heterogenous Omics Information in Cancer
Autore Jin Victor
Pubbl/distr/stampa Frontiers Media SA, 2020
Descrizione fisica 1 electronic resource (154 p.)
Soggetto topico Science: general issues
Medical genetics
Soggetto non controllato Multisource heterogenous omics
cancer
computational cancer biology
genetic
epigenetic
data integration
multi-omics
genome-wide studies
 omics data
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910688321703321
Jin Victor  
Frontiers Media SA, 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Integrative Multi-Omics in Biomedical Research
Integrative Multi-Omics in Biomedical Research
Autore Gerner Christopher
Pubbl/distr/stampa Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
Descrizione fisica 1 electronic resource (178 p.)
Soggetto topico Research & information: general
Biology, life sciences
Soggetto non controllato target identification
target validation
label-free method for drugs
anti-angiogenesis
mechanism of action
receptor tyrosine kinases
curcumin
natural products
lipid
lipidomics
cardiac metaplasia
Barrett's esophagus
esophageal adenocarcinoma
microbiota
DNA sensing
IFI16
cGAS
innate immunity
protein interactions
virus-host interactions
post-translational modifications
mass spectrometry
proteomics
transcriptomics
multi-omics
multi-omics analysis
study design
bioinformatics
machine learning
analysis flow
metabolomics
planned myocardial infarction (PMI)
myocardial infarction (MI)
exercise
heart
cheminformatics
batch variations
eicosanoids
fetal calf serum
peroxisomes
host-pathogen interactions
secretome
macrophages
acute myeloid leukemia
HL-60 cell line
ATRA
induced differentiation
transcriptome
proteome
transcription factors
key molecules
regulatory pathway modelling
SRM
endometriosis
inflammation
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910557769003321
Gerner Christopher  
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Molecular Vaccines against Pathogens in the Post-Genomic Era
Molecular Vaccines against Pathogens in the Post-Genomic Era
Autore Alejandro Oñate Angel
Pubbl/distr/stampa Frontiers Media SA, 2020
Descrizione fisica 1 electronic resource (158 p.)
Soggetto topico Science: general issues
Infectious & contagious diseases
Soggetto non controllato Vaccines
Systems Biology
multi-omics
immunoinformatics
modern vaccinology
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910557539203321
Alejandro Oñate Angel  
Frontiers Media SA, 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
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New Biomolecules and Drug Delivery Systems as Alternatives to Conventional Antibiotics
New Biomolecules and Drug Delivery Systems as Alternatives to Conventional Antibiotics
Autore Felgueiras Helena
Pubbl/distr/stampa Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
Descrizione fisica 1 electronic resource (232 p.)
Soggetto topico Research & information: general
Chemistry
Soggetto non controllato nanoparticles
4-Nerolidylcatechol
antifungals
Microsporum canis
polycaprolactone
nanoprecipitation
silver nanoparticles
green synthesis method
Catharanthus roseus
Azadirachta indica
multidrug-resistant bacteria
wound healing
nosocomial infection
plant extract
grapefruit seed extract
antibacterial activity
fiber-hydrogel composite
biodegradable polymers
skin regeneration
drug delivery platforms
controlled release
tetramycin
antimicrobial activity
kiwifruit disease
conventional antibiotics
storage quality
gold nanoparticles
flavonoids
Gram-negative bacteria
DNA gyrase
in silico
multidrug-resistant Acinetobacter baumannii (MDR-AB)
hypertonic saline
antibiotics
biofilm
aerosol delivery
ultrahigh-throughput screening
live biosensors
antibiotic discovery
gram-negative pathogens
microfluidic droplet cocultivation
efficient promoters
polymyxins
colistin biosynthetic gene cluster
single cell
multi-omics
quercetin
magnesium-doped calcium silicate
osteogenic activity
bone regeneration and nanofiber scaffold
bulk-tank milk
mastitis
methicillin
milk
goat
somatic cell counts
staphylococcus
tetracycline
total bacterial counts
prosthetic joint infection
local prevention
allicin
chitosan
Sphaerotheca sp
antibiotic
Rosa roxburghii
cyclic diphenylphosphonate
quinoline
DNA gyrase inhibitor
molecular docking
magnesium ion
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910585940303321
Felgueiras Helena  
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Nutrition for Brain Development
Nutrition for Brain Development
Autore Mohajeri M. Hasan
Pubbl/distr/stampa Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
Descrizione fisica 1 electronic resource (262 p.)
Soggetto topico Medicine
Neurosciences
Soggetto non controllato cocaine self-administration
high-fat diet
high-sugar diet
maternal diet
pregnancy and lactation
melanocortin-4 receptor
offspring brain
rat offspring
maternal nutrition
protein restriction
fetal brain
hypothalamus
differentiation
neurogenesis
transcriptomics
epitranscriptomics
mitochondria
PKU
cognitive outcomes
cross-cultural
cross-countries
Phe associations
spearmint
rosmarinic acid
polyphenol
amyloid fibril
amyloid beta
alpha-synuclein
Tau
dementia
human milk oligosaccharides
cognition
brain development
animal behaviour
fucosyllactose
sialyllactose
long term potentiation
gut-brain-axis
gut microbiome
short-chain fatty acids
bacterial metabolites
SCFA
manganese
blood-brain barrier
blood-cerebrospinal fluid barrier
choroid plexus
ketogenic supplement
ketosis
aging
lifespan
neurodegenerative disease
learning
memory
early childhood
nutrition
Mediterranean diet
body mass index
cognitive development
multi-omics
microvascular
brain
high glycemic diet
soluble epoxide hydrolase inhibitor
maless
depression
affective disorder
bacteria
probiotics
therapy
treatment
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910566471203321
Mohajeri M. Hasan  
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Statistical and Computational Methods for Microbiome Multi-Omics Data
Statistical and Computational Methods for Microbiome Multi-Omics Data
Autore Mallick Himel
Pubbl/distr/stampa Frontiers Media SA, 2020
Descrizione fisica 1 electronic resource (170 p.)
Soggetto topico Science: general issues
Medical genetics
Soggetto non controllato microbiome
metagenomics
metabolomics
multi-omics
biostatistics
computational biology
statistical genomics
data science
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910557430103321
Mallick Himel  
Frontiers Media SA, 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Systems Analytics and Integration of Big Omics Data
Systems Analytics and Integration of Big Omics Data
Autore Hardiman Gary
Pubbl/distr/stampa MDPI - Multidisciplinary Digital Publishing Institute, 2020
Descrizione fisica 1 electronic resource (202 p.)
Soggetto non controllato precision medicine informatics
drug sensitivity
chromatin modification
cell lines
biocuration
neurodegeneration
multivariate analysis
artificial intelligence
epigenetics
missing data
sequencing
clinical data
class imbalance
integrative analytics
algorithm development for network integration
deep phenotype
non-omics data
feature selection
Gene Ontology
miRNA-gene expression networks
omics data
plot visualization
Alzheimer's disease
tissue classification
epidemiological data
proteomic analysis
genotype
RNA expression
indirect effect
multi-omics
dementia
multiomics integration
data integration
phenomics
network topology analysis
challenges
transcriptome
enrichment analysis
regulatory genomics
scalability
heterogeneous data
systemic lupus erythematosus
database
microtubule-associated protein tau
disease variants
genomics
joint modeling
distance correlation
annotation
phenotype
direct effect
curse of dimensionality
gene-environment interactions
logic forest
machine learning
KEGG pathways
multivariate causal mediation
amyloid-beta
bioinformatics pipelines
support vector machine
pharmacogenomics
candidate genes
tissue-specific expressed genes
cognitive impairment
causal inference
ISBN 3-03928-745-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910404089603321
Hardiman Gary  
MDPI - Multidisciplinary Digital Publishing Institute, 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
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