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Drug Repositioning: Current Advances and Future Perspectives
| Drug Repositioning: Current Advances and Future Perspectives |
| Autore | Yuhei Nishimura |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 online resource (153 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Pharmacology |
| Soggetto non controllato |
computational analysis
data sharing database Drug Repositioning Integrative strategies molecular docking multi-omics Patenting polypharmacology |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Drug Repositioning |
| Record Nr. | UNINA-9910346734903321 |
Yuhei Nishimura
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Identification and Characterization of Genetic Components in Autism Spectrum Disorders 2019
| Identification and Characterization of Genetic Components in Autism Spectrum Disorders 2019 |
| Autore | Butler Merlin G |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (256 p.) |
| Soggetto topico |
Biology, life sciences
Genetics (non-medical) Research & information: general |
| Soggetto non controllato |
15q11.2 BP1-BP2 microdeletion (Burnside-Butler syndrome)
15q11.2 BP1-BP2 microdeletion (Burnside-Butler) syndrome AMPA receptors AmplideX animal model ASD autism autism candidate genes autism spectrum disorder Autism spectrum disorder autism spectrum disorders autism spectrum disorders (ASD) biological networks BMI Body mass index cancer case-control association analysis collapsin response mediator protein 4 CYFIP1 cytokine data integration developmental delays DNA methylation epigenetics expression profile fragile X syndrome gene expression genetics genomics guanine nucleotide exchange factor gut gut-brain interaction heterogeneity reduction IL-6 imprinting intellectual disability leaky gut magnesium transporters and supplementation maternal immune activation mice microbiome microRNA- interactions molecular functions and processes monocyte mosaicism motor delays MS-QMA multi-omics nanostring network diffusion neurodevelopmental disorder NIPA1 NIPA2 NMDA receptors Obesity overlapping genes and gene profiling Overweight parent-of-origin effects pediatrics Phelan McDermid Syndrome phenotype-genotype correlation phenotypes and diseases postnatal VPA injection potential treatment options Prader-Willi and Angelman syndromes ProSAP2 quantitative traits RNA toxicity SAM sex different phenotypes SHANK stratification by trait severity STRING-protein-protein interaction super-pathways synaptic plasticity synaptotagmin-like protein 4 (SYTL4) SYTL4-protein structure T cell cytokine trained immunity transmembrane protein 187 (TMEM187) TUBGCP5 genes whole-exome sequencing β-glucan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566483203321 |
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Butler Merlin G
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Integration of Multisource Heterogenous Omics Information in Cancer
| Integration of Multisource Heterogenous Omics Information in Cancer |
| Autore | Jin Victor |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (154 p.) |
| Soggetto topico |
Medical genetics
Science: general issues |
| Soggetto non controllato |
omics data
cancer computational cancer biology data integration epigenetic genetic genome-wide studies multi-omics Multisource heterogenous omics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910688321703321 |
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Jin Victor
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Integrative Multi-Omics in Biomedical Research
| Integrative Multi-Omics in Biomedical Research |
| Autore | Gerner Christopher |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (178 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
acute myeloid leukemia
analysis flow anti-angiogenesis ATRA Barrett's esophagus batch variations bioinformatics cardiac metaplasia cGAS cheminformatics curcumin DNA sensing eicosanoids endometriosis esophageal adenocarcinoma exercise fetal calf serum heart HL-60 cell line host-pathogen interactions IFI16 induced differentiation inflammation innate immunity key molecules label-free method for drugs lipid lipidomics machine learning macrophages mass spectrometry mechanism of action metabolomics microbiota multi-omics multi-omics analysis myocardial infarction (MI) n/a natural products peroxisomes planned myocardial infarction (PMI) post-translational modifications protein interactions proteome proteomics receptor tyrosine kinases regulatory pathway modelling secretome SRM study design target identification target validation transcription factors transcriptome transcriptomics virus-host interactions |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557769003321 |
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Gerner Christopher
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Vaccines against Pathogens in the Post-Genomic Era
| Molecular Vaccines against Pathogens in the Post-Genomic Era |
| Autore | Alejandro Oñate Angel |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (158 p.) |
| Soggetto topico |
Infectious & contagious diseases
Science: general issues |
| Soggetto non controllato |
immunoinformatics
modern vaccinology multi-omics Systems Biology Vaccines |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557539203321 |
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Alejandro Oñate Angel
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Biomolecules and Drug Delivery Systems as Alternatives to Conventional Antibiotics
| New Biomolecules and Drug Delivery Systems as Alternatives to Conventional Antibiotics |
| Autore | Felgueiras Helena |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (232 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
4-Nerolidylcatechol
aerosol delivery allicin antibacterial activity antibiotic antibiotic discovery antibiotics antifungals antimicrobial activity Azadirachta indica biodegradable polymers biofilm bone regeneration and nanofiber scaffold bulk-tank milk Catharanthus roseus chitosan colistin biosynthetic gene cluster controlled release conventional antibiotics cyclic diphenylphosphonate DNA gyrase DNA gyrase inhibitor drug delivery platforms efficient promoters fiber-hydrogel composite flavonoids goat gold nanoparticles Gram-negative bacteria gram-negative pathogens grapefruit seed extract green synthesis method hypertonic saline in silico kiwifruit disease live biosensors local prevention magnesium ion magnesium-doped calcium silicate mastitis methicillin microfluidic droplet cocultivation Microsporum canis milk molecular docking multi-omics multidrug-resistant Acinetobacter baumannii (MDR-AB) multidrug-resistant bacteria n/a nanoparticles nanoprecipitation nosocomial infection osteogenic activity plant extract polycaprolactone polymyxins prosthetic joint infection quercetin quinoline Rosa roxburghii silver nanoparticles single cell skin regeneration somatic cell counts Sphaerotheca sp staphylococcus storage quality tetracycline tetramycin total bacterial counts ultrahigh-throughput screening wound healing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585940303321 |
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Felgueiras Helena
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutrition for Brain Development
| Nutrition for Brain Development |
| Autore | Mohajeri M. Hasan |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (262 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
affective disorder
aging alpha-synuclein amyloid beta amyloid fibril animal behaviour bacteria bacterial metabolites blood-brain barrier blood-cerebrospinal fluid barrier body mass index brain brain development choroid plexus cocaine self-administration cognition cognitive development cognitive outcomes cross-countries cross-cultural dementia depression differentiation early childhood epitranscriptomics fetal brain fucosyllactose gut microbiome gut-brain-axis high glycemic diet high-fat diet high-sugar diet human milk oligosaccharides hypothalamus ketogenic supplement ketosis learning lifespan long term potentiation maless manganese maternal diet maternal nutrition Mediterranean diet melanocortin-4 receptor memory microvascular mitochondria multi-omics n/a neurodegenerative disease neurogenesis nutrition offspring brain Phe associations PKU polyphenol pregnancy and lactation probiotics protein restriction rat offspring rosmarinic acid SCFA short-chain fatty acids sialyllactose soluble epoxide hydrolase inhibitor spearmint Tau therapy transcriptomics treatment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566471203321 |
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Mohajeri M. Hasan
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Statistical and Computational Methods for Microbiome Multi-Omics Data
| Statistical and Computational Methods for Microbiome Multi-Omics Data |
| Autore | Mallick Himel |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (170 p.) |
| Soggetto topico |
Medical genetics
Science: general issues |
| Soggetto non controllato |
biostatistics
computational biology data science metabolomics metagenomics microbiome multi-omics statistical genomics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557430103321 |
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Mallick Himel
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Systems Analytics and Integration of Big Omics Data
| Systems Analytics and Integration of Big Omics Data |
| Autore | Hardiman Gary |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (202 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
algorithm development for network integration
Alzheimer's disease amyloid-beta annotation artificial intelligence biocuration bioinformatics pipelines candidate genes causal inference cell lines challenges chromatin modification class imbalance clinical data cognitive impairment curse of dimensionality data integration database deep phenotype dementia direct effect disease variants distance correlation drug sensitivity enrichment analysis epidemiological data epigenetics feature selection Gene Ontology gene-environment interactions genomics genotype heterogeneous data indirect effect integrative analytics joint modeling KEGG pathways logic forest machine learning microtubule-associated protein tau miRNA-gene expression networks missing data multi-omics multiomics integration multivariate analysis multivariate causal mediation n/a network topology analysis neurodegeneration non-omics data omics data pharmacogenomics phenomics phenotype plot visualization precision medicine informatics proteomic analysis regulatory genomics RNA expression scalability sequencing support vector machine systemic lupus erythematosus tissue classification tissue-specific expressed genes transcriptome |
| ISBN | 3-03928-745-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404089603321 |
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Hardiman Gary
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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