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Advances in Mucoadhesive Polymers and Formulations for Transmucosal Drug Delivery
| Advances in Mucoadhesive Polymers and Formulations for Transmucosal Drug Delivery |
| Autore | Khutoryanskiy Vitaliy |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (206 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
acrylated chitosan
alkyl lactate Alzheimer's disease biocompatibility buccal mucosa drug delivery Caco-2 cells Candida albicans Carbopol Carbopol® chitosan chitosan derivatives chitosan-catechol clobetasol clotrimazole controlled release cyclodextrins cytotoxicity detachment force drug delivery electrospinning Eudragit® E PO films furosemide gellan gum hydrogel hydroxypropyl cellulose in vitro permeability interpolyelectrolyte complex interpolymer complexes l-arginine liposphere maltodextrin mucoadhesion mucoadhesive mucoadhesive microspheres mucoadhesive polymer mucoadhesive polymers mucosal drug delivery mucosal membranes nanoparticles omeprazole oral lichen planus oral lyophilisates paediatric pectin pioglitazone PLGA-PEG pluronic f127 poly (vinylpyrrolidone) poly(2-ethyl-2-oxazoline) resuspendibility resveratrol retention rheology scanning electron microscopic images storage and loss moduli texture profile analysis thermogelling polymers thermoresponsive polymers thiolated chitosan thiolated hyaluronic acid transmucosal permeations trimethyl chitosan triple co-culture model wound healing xanthan gum |
| ISBN | 3-03928-753-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404086403321 |
Khutoryanskiy Vitaliy
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Current Insights on Lipid-Based Nanosystems
| Current Insights on Lipid-Based Nanosystems |
| Autore | Silva Ana Catarina |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
Echinococcus granulosus
scolicidal nanoliposome juglone apoptotic activity hydrogel SLNs nose-to-brain delivery mucoadhesion quality by design antioxidant activity nasal administration nanostructured lipid carriers solid lipid nanoparticles in vitro cell cultures 3D nasal casts lung cancer targeted drug delivery lipid-based nanocarriers pulmonary delivery dry powder inhalers aerosols liposomes nanoemulsions nanotechnology biologically active compounds dermal drug delivery polyphenols phytophenols skin permeation chemotherapy radiotherapy active targeting passive targeting tumor immunoconjugate traditional liposome stealth liposome triggered release limitations of liposomes drug transfer in vitro release colloidal drug carriers lipid nanoparticles hydrogel beads cholesteryl nonanoate bovine serum albumin skin diseases lipid-based nanosystems cream ointment gel pH-sensitive liposome imidazole anticancer drug delivery multicellular spheroids dapagliflozin Box-Behnken design FTIR DSC XRD SEM AFM in vitro Franz diffusion cells lipid-based nanoparticles nanocarrier surface charge delivery systems chronic treatment mice anti-oxidant activity hepatoprotective effect phospholipid phytosomes Silymarin Colorectal Cancer Niosomes Oxaliplatin Paclitaxel d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) therapeutic nucleic acids schizophrenia quetiapine fumarate glycerosomes central composite rotatable design bioavailability pharmacokinetic |
| ISBN | 3-0365-6165-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639995103321 |
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Silva Ana Catarina
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Chitin 2019
| Marine Chitin 2019 |
| Autore | Sashiwa Hitoshi |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (288 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
?-glucosidase inhibitor
2D correlation spectroscopy amphiphilic polymer anti-inflammatory action antibacterial activity antifungal activity antioxidant antioxidant activity Aplysina archeri ball milling biofilms biotechnology blood bromotyrosines bulk density Caco-2 cell culture chitin chitin deacetylase chitinase chitooligosaccharide chitooligosaccharides chitosan chitosan citrate chitosan hydrogel chitosan lactate chitosan oleate salt chitosan oligomers chitosan oligosaccharides chitosan tartrate chitosan-coated liposomes chitosanase Clostridium perfringens collagen compression work conjugation crude oil crushing strength curcumin cytotoxicity derivatization direct compression dissolution electrospinning enzymatic modification Eudragit® S100 express method Hausner ratio HIV sexual transmission immunostimulatory activity Kawakita analysis layer-by-layer film lytic polysaccharide monooxygenase marine resources marine sponges mechanical property methylene blue mitogen-activated protein kinases (MAPK) mucoadhesion mucoadhesive film nanocomposites nanoparticles nile red Paenibacillus pH responsive release phosphoinositide 3-kinases (PI3K)/Akt PLGA Polybius henslowii polymer film polymorph pork sausage protease Pseudomonas aeruginosa RAW 264.7 cells RAW264.7 macrophage roller compaction scaffolds sodium carbonate soluble chitosan complex Staphylococcus aureus Staphylococcus epidermidis streptomycin Tenofovir controlled release vaginal infections vaginal preexposure prophylaxis wound treatment |
| ISBN | 3-03936-073-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404078203321 |
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Sashiwa Hitoshi
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Polymers Enhancing Bioavailability in Drug Delivery
| Polymers Enhancing Bioavailability in Drug Delivery |
| Autore | Fernandes Ana Isabel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
cystic fibrosis
Pseudomonas aeruginosa liposomes efflux pump inhibitor PABN aminoglycosides macrolides poloxamer thiourea thiolation mucoadhesion drug release in vivo analysis in vitro dissolution studies S-propargyl-cysteine poly(lactic acid) endogenous hydrogen sulfide water-in-oil-in-water rheumatoid arthritis chitosan drug delivery drug absorption intestinal assimilation oral bioavailability nanoemulsions micelles SEDDS zeta potential sustained release albumin nanoparticle MPT0B291 high-pressure homogenizer histone deacetylase calix[8]arenes silibinin inclusion complexes PEGylation cytotoxicity oromucosal films sodium alginate nanoparticle drug carriers digoxin zein heart failure polymer-liposome complexes Pluronic®-poly(acrylic acid) Pluronic®-poly(N,N-dimethylaminoethyl methacrylate) stimuli-responsive intelligent drug delivery systems liposome polymer long circulation polymer-lipid conjugates targeting stimulus-responsive antibody affinity cyclodextrin protein therapeutics sustained drug delivery Nitric oxide hydrogel wound dressing chronic wounds glycyrrhetinic acid Soluplus® solid dispersions anti-inflammatory biosafety bioavailability |
| ISBN | 3-0365-5683-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637795003321 |
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Fernandes Ana Isabel
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation
| Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation |
| Autore | Gonzalez-Alvarez Maria Isabel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (238 p.) |
| Soggetto topico |
Manufacturing industries
Medicine and Nursing |
| Soggetto non controllato |
absorption-modifying excipients
BCS class IV drugs BCS drugs bioequivalence biomimetic membrane biopharmaceutics biopharmaceutics classification system Biopharmaceutics Classification System clinical studies colon absorption combined zero- and first-order absorption controlled release drug product DDI disintegration dissolution dissolution test drug absorption drug permeability drug solubility drug solubility/dissolution drug-drug interactions energy intake enteric-coated first-order absorption first-pass effect Franz cell Franz-PAMPA furosemide gastrointestinal gastrointestinal hormone GastroPlus hierarchical support vector regression (HSVR) human colon carcinoma cell layer (Caco-2) ibuprofen ICH in silico modeling in situ perfusion in vitro in vitro in vivo extrapolations intestinal absorption intestinal perfusion intestinal permeability IVIVE location-dependent absorption manometry mechanistic modeling microdevices mucoadhesion nutrient absorption nutrient digestion obesity oral absorption oral drug delivery oral peptide delivery passive drug transport PBBM PBPK permeation enhancers pharmaceutical development pharmacokinetics Phoenix WinNonlin physiologically-based pharmacokinetic (PBPK) modeling postprandial glycaemia pravastatin quality control region of the gut regional intestinal permeability regional/segmental-dependent permeability and absorption route-dependent intestinal metabolism segmental-dependent intestinal permeability segregated flow intestinal model (SFM) shape traditional model (TM) transit compartment absorption model type 2 diabetes zero-order absorption |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Regional Intestinal Drug Absorption |
| Record Nr. | UNINA-9910566462603321 |
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Gonzalez-Alvarez Maria Isabel
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Semisolid Dosage
| Semisolid Dosage |
| Autore | Daniels Rolf |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (182 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
acceptance criteria
Amphotericin B antibacterial birch bark extract budesonide chitosan compounded preparation confocal Raman spectroscopy (CRS) curcumin cutaneous leishmaniasis deformable liposomes dermal delivery dermal drug delivery diffusion cell discriminatory ability drug delivery eosinophilic esophagitis esophagus permeability FDA's SUPAC-SS guidance Franz diffusion gel strength guar gum human excised skin hydrogel hydrogen bonding in situ hydrogel-forming powder in vitro in vitro permeation intercellular lipids IVRT Jurkat cells Leishmania infantum liposome surface charge methadone methyl cellulose metronidazole mucoadhesion n/a nanocarrier nanogels niacinamide nitric oxide-releasing formulation non-ionic emulsifiers nonivamide oleogels pain PAMPA pediatric medicine permeation polyethylene glycol alkyl ethers polyethylene glycol sorbitan fatty acid esters porcine skin positive and negative controls rheological characterization rheology S-nitrosoglutathione (GSNO) sameness semisolid dosage forms Sepigel 305® skin skin penetration Skin-PAMPA solvent Strat-M® membrane substantivity tacrolimus formulation thermogel topical cream topical treatment triterpene wound dressing wound healing wound therapy xanthan gum |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557436403321 |
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Daniels Rolf
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transmucosal Absorption Enhancers in the Drug Delivery Field
| Transmucosal Absorption Enhancers in the Drug Delivery Field |
| Autore | Maher Sam |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (406 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
absorption enhancement
absorption enhancer absorption enhancers absorption modifying excipients Aloe vera amino acid amphiphilic polymers and liposome antiepileptic drug antimicrobial peptide biocompatibility studies bioenhancer block copolymers brush border Caco-2 Caco-2 cells cationic functionalization cell-penetrating peptide cell-penetrating peptide (CPP) cervicovaginal tumors chitosan chitosan derivatives claudin clinical trial CNS disorders combined microsphere compound 48/80 confocal laser scanning microscopy cornea curcumin cyclodextrin cytochrome P450 drug absorption enhancer drug administration drug delivery efflux enterocyte epithelial permeability epithelial transport epithelium F-actin FITC-dextran formulation gel gemini surfactant GLP-1 hydrophobization imatinib in situ hydrogel in vivo studies insulin intestinal absorption intestinal delivery intestinal epithelial cells intestinal permeation enhancers KLAL man mast cell activator metabolism mucoadhesion mucoadhesiveness N-dodecyl-?-D-maltoside (DDM) nanocapsules nanocrystals nanomedicine nanoparticle nanoparticles nasal nasal delivery nasal formulation nasal permeability nasal vaccination nose to brain delivery nose to brain transport nose-to-brain ocular conditions ocular delivery ocular drug delivery ophthalmology oral delivery oral macromolecule delivery oral peptides osteoporosis P-glycoprotein penetration enhancer penetration enhancers permeability permeation enhancer permeation enhancers pharmacokinetic interaction pharmacokinetics PN159 polymeric micelles poorly absorbed drug preclinical PTH 1-34 pulmonary quaternization safety salcaprozate sodium sheep simulated intestinal fluid simvastatin small intestine sodium caprate sodium cholate (NaC) sugar-based surfactants teriparatide thermogel system tight junction tight junction modulator tight junctions transepithelial electrical resistance transferrin transmucosal drug delivery transmucosal permeation tryptophan vaccine adjuvant vaginal delivery whole leaf |
| ISBN | 3-03921-849-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910372785603321 |
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Maher Sam
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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