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Advances in Mucoadhesive Polymers and Formulations for Transmucosal Drug Delivery
| Advances in Mucoadhesive Polymers and Formulations for Transmucosal Drug Delivery |
| Autore | Khutoryanskiy Vitaliy |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (206 p.) |
| Soggetto non controllato |
chitosan
maltodextrin Caco-2 cells alkyl lactate mucosal drug delivery thermogelling polymers buccal mucosa drug delivery drug delivery triple co-culture model oral lichen planus mucoadhesive polymers cyclodextrins paediatric mucoadhesion nanoparticles pectin furosemide oral lyophilisates films wound healing pluronic f127 interpolymer complexes transmucosal permeations Alzheimer’s disease biocompatibility poly (vinylpyrrolidone) mucosal membranes scanning electron microscopic images pioglitazone hydrogel resuspendibility thermoresponsive polymers mucoadhesive microspheres trimethyl chitosan Candida albicans xanthan gum omeprazole texture profile analysis acrylated chitosan mucoadhesive clotrimazole clobetasol Carbopol® hydroxypropyl cellulose electrospinning chitosan derivatives in vitro permeability l-arginine resveratrol cytotoxicity retention thiolated hyaluronic acid Carbopol mucoadhesive polymer rheology Eudragit® E PO detachment force chitosan-catechol controlled release PLGA-PEG liposphere gellan gum storage and loss moduli thiolated chitosan interpolyelectrolyte complex poly(2-ethyl-2-oxazoline) |
| ISBN | 3-03928-753-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404086403321 |
Khutoryanskiy Vitaliy
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Current Insights on Lipid-Based Nanosystems
| Current Insights on Lipid-Based Nanosystems |
| Autore | Silva Ana Catarina |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
Echinococcus granulosus
scolicidal nanoliposome juglone apoptotic activity hydrogel SLNs nose-to-brain delivery mucoadhesion quality by design antioxidant activity nasal administration nanostructured lipid carriers solid lipid nanoparticles in vitro cell cultures 3D nasal casts lung cancer targeted drug delivery lipid-based nanocarriers pulmonary delivery dry powder inhalers aerosols liposomes nanoemulsions nanotechnology biologically active compounds dermal drug delivery polyphenols phytophenols skin permeation chemotherapy radiotherapy active targeting passive targeting tumor immunoconjugate traditional liposome stealth liposome triggered release limitations of liposomes drug transfer in vitro release colloidal drug carriers lipid nanoparticles hydrogel beads cholesteryl nonanoate bovine serum albumin skin diseases lipid-based nanosystems cream ointment gel pH-sensitive liposome imidazole anticancer drug delivery multicellular spheroids dapagliflozin Box-Behnken design FTIR DSC XRD SEM AFM in vitro Franz diffusion cells lipid-based nanoparticles nanocarrier surface charge delivery systems chronic treatment mice anti-oxidant activity hepatoprotective effect phospholipid phytosomes Silymarin Colorectal Cancer Niosomes Oxaliplatin Paclitaxel d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) therapeutic nucleic acids schizophrenia quetiapine fumarate glycerosomes central composite rotatable design bioavailability pharmacokinetic |
| ISBN | 3-0365-6165-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639995103321 |
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Silva Ana Catarina
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Chitin 2019
| Marine Chitin 2019 |
| Autore | Sashiwa Hitoshi |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto non controllato |
chitosan hydrogel
chitosan biotechnology RAW264.7 macrophage ?-glucosidase inhibitor bromotyrosines layer-by-layer film amphiphilic polymer conjugation marine resources antioxidant activity chitooligosaccharides methylene blue nanoparticles bulk density Eudragit® S100 lytic polysaccharide monooxygenase chitosan oleate salt curcumin RAW 264.7 cells antioxidant crude oil ball milling anti-inflammatory action enzymatic modification dissolution vaginal infections Hausner ratio crushing strength Staphylococcus epidermidis mucoadhesive film Caco-2 cell culture chitosan lactate 2D correlation spectroscopy chitosan citrate direct compression chitosan oligomers chitin deacetylase Pseudomonas aeruginosa collagen blood express method sodium carbonate HIV sexual transmission streptomycin antibacterial activity pork sausage nanocomposites chitosanase Clostridium perfringens chitinase mucoadhesion chitosan oligosaccharides chitosan tartrate Staphylococcus aureus immunostimulatory activity derivatization pH responsive release soluble chitosan complex chitin polymer film compression work wound treatment biofilms roller compaction mitogen-activated protein kinases (MAPK) Paenibacillus chitooligosaccharide mechanical property protease Polybius henslowii scaffolds electrospinning chitosan-coated liposomes phosphoinositide 3-kinases (PI3K)/Akt cytotoxicity polymorph vaginal preexposure prophylaxis Aplysina archeri antifungal activity PLGA Kawakita analysis marine sponges Tenofovir controlled release nile red |
| ISBN | 3-03936-073-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404078203321 |
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Sashiwa Hitoshi
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Polymers Enhancing Bioavailability in Drug Delivery
| Polymers Enhancing Bioavailability in Drug Delivery |
| Autore | Fernandes Ana Isabel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
cystic fibrosis
Pseudomonas aeruginosa liposomes efflux pump inhibitor PABN aminoglycosides macrolides poloxamer thiourea thiolation mucoadhesion drug release in vivo analysis in vitro dissolution studies S-propargyl-cysteine poly(lactic acid) endogenous hydrogen sulfide water-in-oil-in-water rheumatoid arthritis chitosan drug delivery drug absorption intestinal assimilation oral bioavailability nanoemulsions micelles SEDDS zeta potential sustained release albumin nanoparticle MPT0B291 high-pressure homogenizer histone deacetylase calix[8]arenes silibinin inclusion complexes PEGylation cytotoxicity oromucosal films sodium alginate nanoparticle drug carriers digoxin zein heart failure polymer-liposome complexes Pluronic®-poly(acrylic acid) Pluronic®-poly(N,N-dimethylaminoethyl methacrylate) stimuli-responsive intelligent drug delivery systems liposome polymer long circulation polymer-lipid conjugates targeting stimulus-responsive antibody affinity cyclodextrin protein therapeutics sustained drug delivery Nitric oxide hydrogel wound dressing chronic wounds glycyrrhetinic acid Soluplus® solid dispersions anti-inflammatory biosafety bioavailability |
| ISBN | 3-0365-5683-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637795003321 |
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Fernandes Ana Isabel
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation
| Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation |
| Autore | Gonzalez-Alvarez Maria Isabel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
bioequivalence
Biopharmaceutics Classification System in vitro dissolution test pravastatin oral absorption in silico modeling GastroPlus Phoenix WinNonlin pharmacokinetics clinical studies ibuprofen manometry gastrointestinal mechanistic modeling PBPK PBBM disintegration dissolution enteric-coated ICH quality control regional intestinal permeability permeation enhancers absorption-modifying excipients oral peptide delivery intestinal perfusion pharmaceutical development controlled release drug product biopharmaceutics classification system drug solubility drug permeability location-dependent absorption segregated flow intestinal model (SFM) traditional model (TM) route-dependent intestinal metabolism first-pass effect drug-drug interactions DDI in vitro in vivo extrapolations IVIVE zero-order absorption first-order absorption combined zero- and first-order absorption transit compartment absorption model in situ perfusion microdevices shape mucoadhesion colon absorption nutrient digestion nutrient absorption gastrointestinal hormone postprandial glycaemia energy intake region of the gut obesity type 2 diabetes Franz–PAMPA BCS drugs biomimetic membrane Franz cell passive drug transport BCS class IV drugs segmental-dependent intestinal permeability intestinal absorption oral drug delivery biopharmaceutics physiologically-based pharmacokinetic (PBPK) modeling furosemide intestinal permeability human colon carcinoma cell layer (Caco-2) hierarchical support vector regression (HSVR) drug absorption drug solubility/dissolution regional/segmental-dependent permeability and absorption |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Regional Intestinal Drug Absorption |
| Record Nr. | UNINA-9910566462603321 |
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Gonzalez-Alvarez Maria Isabel
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Semisolid Dosage
| Semisolid Dosage |
| Autore | Daniels Rolf |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (182 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
dermal drug delivery
diffusion cell Franz diffusion Skin-PAMPA Strat-M® membrane nanocarrier nonivamide methyl cellulose skin penetration substantivity thermogel tacrolimus formulation nanogels drug delivery human excised skin Jurkat cells in situ hydrogel-forming powder nitric oxide-releasing formulation S-nitrosoglutathione (GSNO) antibacterial wound dressing wound healing dermal delivery porcine skin in vitro permeation methadone pain in vitro permeation niacinamide solvent PAMPA skin curcumin deformable liposomes liposome surface charge hydrogel chitosan wound therapy IVRT metronidazole topical cream semisolid dosage forms sameness FDA's SUPAC-SS guidance acceptance criteria positive and negative controls discriminatory ability Amphotericin B Sepigel 305® Leishmania infantum cutaneous leishmaniasis topical treatment birch bark extract oleogels hydrogen bonding triterpene rheology gel strength eosinophilic esophagitis budesonide xanthan gum guar gum mucoadhesion esophagus permeability rheological characterization pediatric medicine compounded preparation non-ionic emulsifiers intercellular lipids confocal Raman spectroscopy (CRS) polyethylene glycol alkyl ethers polyethylene glycol sorbitan fatty acid esters |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557436403321 |
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Daniels Rolf
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transmucosal Absorption Enhancers in the Drug Delivery Field
| Transmucosal Absorption Enhancers in the Drug Delivery Field |
| Autore | Maher Sam |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (406 p.) |
| Soggetto non controllato |
chitosan
intestinal epithelial cells ocular delivery amphiphilic polymers cornea tight junction modulator cyclodextrin permeability gemini surfactant transferrin compound 48/80 epithelial permeability cervicovaginal tumors nanoparticles confocal laser scanning microscopy safety formulation salcaprozate sodium intestinal absorption FITC-dextran curcumin block copolymers nasal vaccination whole leaf brush border ocular drug delivery vaccine adjuvant nanoparticle nasal delivery efflux permeation enhancers absorption enhancers nose to brain delivery small intestine epithelium CNS disorders absorption modifying excipients insulin absorption enhancer gel intestinal delivery thermogel system Caco-2 biocompatibility studies absorption enhancement man PN159 poorly absorbed drug tryptophan tight junction oral macromolecule delivery penetration enhancer intestinal permeation enhancers nanocrystals simvastatin nanomedicine enterocyte N-dodecyl-?-D-maltoside (DDM) cell-penetrating peptide quaternization KLAL nasal nasal permeability transmucosal drug delivery Caco-2 cells mast cell activator penetration enhancers drug delivery nose-to-brain bioenhancer polymeric micelles mucoadhesion cell-penetrating peptide (CPP) simulated intestinal fluid vaginal delivery nasal formulation pharmacokinetic interaction sodium caprate clinical trial transmucosal permeation drug absorption enhancer sugar-based surfactants nanocapsules imatinib teriparatide osteoporosis hydrophobization F-actin combined microsphere transepithelial electrical resistance oral delivery ocular conditions metabolism antimicrobial peptide permeation enhancer drug administration antiepileptic drug amino acid in vivo studies sodium cholate (NaC) epithelial transport preclinical nose to brain transport pharmacokinetics chitosan derivatives ophthalmology tight junctions sheep cationic functionalization GLP-1 pulmonary and liposome cytochrome P450 claudin P-glycoprotein in situ hydrogel mucoadhesiveness PTH 1-34 Aloe vera oral peptides |
| ISBN | 3-03921-849-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910372785603321 |
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Maher Sam
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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