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Animal Modeling in Cancer
| Animal Modeling in Cancer |
| Autore | Korinek Vladimir |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (273 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
soy
isoflavones mammary tumor prevention rodent models chemical carcinogens transgenic mice Zebrafish Drosophila rats mice NPM-1 FLT3 ITD ETO-1 IDH1/2 neural stem cells brain and nervous system cancers neurogenic niches radiotherapy sparing of neurogenic regions carcinoma consensus molecular subtypes intestine oncogenes signaling cascades tumor suppressors tumorigenesis MPN (myeloproliferative neoplasms) zebrafish iPSCs JAK2 MPL CALR thrombosis ubiquitin–proteasome system cancer mouse model gene inactivation colorectal cancer mouse models microbiota antitumor immunity melanoma mutation genetics animal model swine MeLiM progression spontaneous regression devitalization metaplasia Cdx animal models epigenetics xenotransplantation drug screen pre-clinical cancer model non-mouse models gene editing stem cells solid tumors hematologic malignancies |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557344403321 |
Korinek Vladimir
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Distributed networks [[electronic resource] ] : new outlooks on cerebellar function / / edited by Thomas C. Watson, Stella Koutsikou, Richard Apps and Matthew W. Jones
| Distributed networks [[electronic resource] ] : new outlooks on cerebellar function / / edited by Thomas C. Watson, Stella Koutsikou, Richard Apps and Matthew W. Jones |
| Autore | Stella Koutsikou |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 online resource (211 pages) : illustrations, charts |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
Cerebellum
mouse models purkine cell Autism Spectrum Disorders Cerebellar Nuclei internal model networks zebrin oscillations distributed network |
| ISBN | 9782889196265 (ebook) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Distributed Networks |
| Record Nr. | UNINA-9910137094003321 |
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Stella Koutsikou
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| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug delivery technology development in Canada / / special issue editors, Kishor M. Wasan, Ildiko Badea
| Drug delivery technology development in Canada / / special issue editors, Kishor M. Wasan, Ildiko Badea |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (352 p.) |
| Disciplina | 615.1/900971 |
| Soggetto topico | Drug Delivery Systems - Canada |
| Soggetto non controllato |
encapsulation
biodistribution pharmaceutics targeted therapies gambogic acid GE11 peptide formulation and dosage form development transient modulation ROESY NMR spectroscopy bioaccessibility polymeric micelle pharmacological Inhibitors of HIF-1 and STAT3 nanoparticles Vitamin D drug discovery EGFR-targeted therapy translational research clinical trials doxorubicin dissolution drug development permeation enhancers Canada plant primary central nervous system lymphomas photostabilizers head and neck squamous cell carcinoma mouse models drug delivery systems melphalan hypoxia-induced chemoresistance skin virus circadian clock child friendly formulation adenanthin co-delivery canola oil deodorizer distillate Metaplex innovation controlled drug delivery nifedipine radiolabeling amphotericin B biological barriers blood-brain barrier (BBB) biologicals lipid nanoparticles oral formulation phytosterols medical devices chronotherapy oral cationic gemini surfactant route of administration drug delivery intra-arterial chemotherapy developing world sustained delivery water miscible solvents combination therapy antibodies throughput magnetic fields liposomes medulloblastoma drug-resistant melanoma rosmarinic acid topical formulation TNO gastrointestinal model gastrointestinal simulator malignant gliomas transdermal drug delivery oral delivery precision medicine 3D spheroid flavonoids staurosporine DOX-Vit D loading gradients bacteriophage phospholipid complex triggered drug release HIF-1 phage display pharmacokinetics emulsion quercetin cisplatin parasitic infections remote loading HAV6 cadherin peptide blood-brain barrier inclusion complex tocopherols STAT3 ultrasound liposome fungal infections magnetic resonance imaging (MRI) MG63 model orange juice radiation cancer mefloquine small molecules |
| ISBN | 3-03928-005-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367736503321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Genomics and Models of Nerve Sheath Tumors
| Genomics and Models of Nerve Sheath Tumors |
| Autore | Hirbe Angela C |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (172 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
neurofibromatosis type 1
nerve sheath tumor cancer latent variables machine learning supervised learning transfer learning random forest metaVIPER tumor deconvolution neurofibromatosis malignant peripheral nerve sheath tumor MPNST polycomb repressive complex PRC2 NF1 kinase kinome adaptation kinome reprogramming MET MEK doxorubicin capmatinib tram genomics tumor evolution pathology next generation sequencing clinical genetics malignant peripheral nerve sheath tumors plexiform neurofibromas Schwann cells neurofibromatosis type 1 syndrome neurofibromin 1 genetically engineered mouse models heterogeneity CRISPR/Cas9 mouse models sarcoma tumor microenvironment neurofibromatosis 1 (NF1) mebendazole (MBZ) COX-2 inhibitor malignancy chemoprevention nerve sheath tumors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557484703321 |
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Hirbe Angela C
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Hedgehog Signaling in Organogenesis and Tumor Microenvironment
| Hedgehog Signaling in Organogenesis and Tumor Microenvironment |
| Autore | Shimo Tsuyoshi |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (172 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Cyp26 enzymes
congenital anomalies CRE/LoxP hedgehog signaling mouse models retinoic acid smoothened sonic hedgehog sonic hedgehog (SHH) oral squamous cell carcinoma (OSCC) tumor microenvironment (TME) tumor-associated macrophages (TAMs) cancer-associated fibroblasts (CAFs) tumor-associated angiogenesis hedgehog growth plate endochondral ossification chondrocyte osteoblast bone disease TMJ synovial joint articular disc Ihh PTHrP osteoarthritis epithelial-mesenchymal interaction (EMI) prostate cancer external genitalia androgen basement membrane bone morphogenetic protein stem cell animal experiment fracture healing cancer stem cells hypospadias urethra penis bone hedgehog signalling tooth development epithelial and mesenchymal interaction Gli1 mesenchymal stem cell lineage tracing analysis stem cell marker |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557628803321 |
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Shimo Tsuyoshi
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Human Tumor-Derived p53 Mutants: A Growing Family of Oncoproteins
| Human Tumor-Derived p53 Mutants: A Growing Family of Oncoproteins |
| Autore | Giovanni Blandino |
| Pubbl/distr/stampa | Frontiers Media SA, 2016 |
| Descrizione fisica | 1 electronic resource (97 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
mouse models
mutant p53 dominant netagive therapies Oncogenic addiction gain of function |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Human Tumor-Derived p53 Mutants |
| Record Nr. | UNINA-9910220041203321 |
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Giovanni Blandino
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| Frontiers Media SA, 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Insulin-Like Growth Factors in Development, Cancers and Aging
| Insulin-Like Growth Factors in Development, Cancers and Aging |
| Autore | Werner Haim |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
IGF-I
IGF-II insulin IGF-IR IRs tyrosine kinase receptor GPCRs hybrids phosphorylation G-proteins β-arrestins functional RTK/GPCR hybrid nuclear translocation IGF-I receptor signaling targeted therapeutics IGF-Trap IGF system IGFBP-3 IGFBP-3R TMEM219 anti-tumor anti-metastatic agonists mAb therapy IGF-1 IGFBP-1 older adults longevity health-span age-related disease cognitive impairment diabetes mitochondria growth hormone insulin-like growth factor-1 aging oxidative stress senescence longitudinal study IGFBP mouse models skeletal muscle MSCs myogenesis glucose regulated protein (GRP) 94 insulin-like growth factor obligate chaperone hypertrophy atrophy cachexia muscle regeneration autophagy IGF-1R insulin receptor IR-A structural studies receptor activation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557735703321 |
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Werner Haim
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Biology of Selenium in Health and Disease
| Molecular Biology of Selenium in Health and Disease |
| Autore | Tsuji Petra A |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (384 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
selenoproteome
selenoprotein hierarchy nonradioactive isotopes SEC-ICP MS glutathione peroxidase thioredoxin reductase SECIS translation regulation autoimmune thyroid disease diabetes mellitus Graves' disease Hashimoto thyroiditis infection inflammation long-COVID rheumatoid arthritis selenoprotein P sepsis selenoprotein W thioredoxin 14-3-3 Akt cell death Selenof selenium selenoprotein colon cancer barrier integrity cardiovascular heart selenoproteins Keshan's Disease bacteria selenite selenium delivery system Trsp hypothalamus Agrp neuron sex differences diet-induced obesity leptin resistance macrophage differentiation redox signaling NRF2 NF-κB lipid mediators seleocysteine autoimmunity lymphocyte cadmium cytotoxicity cancer therapy cisplatin ICP-MS nonsynonymous mutation selenium homeostasis ZIP8 Trit1 isopentenylation tRNA[Ser]Sec selenocysteine genetic variance human disease selenophosphate synthetase endothelial cell reactive oxygen species cell growth angiogenesis SEPHS1 early embryogenesis embryonic lethality prostate cancer tumor suppressor selenoprotein deficiency SECISBP2 Sec-tRNA[Ser]Sec SEPSECS antioxidative defense autoantibody Hashimoto's thyroiditis trace element recoding SECIS-binding protein translation termination nonsense-mediated decay ribosome rescue health mouse models selenocysteine (Sec) virus viral antioxidant HIV HCV HBV coxsackie virus influenza HIV-1 viral infection SELENOS SELENOO primary T cells Jurkat SupT1 translational control |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566482103321 |
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Tsuji Petra A
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neuroanatomy and transgenic technologies / / topic editors, Alexander C. Jackson, Chen Liu, Makoto Fukuda, Michael Lazarus and Laurent Gautron
| Neuroanatomy and transgenic technologies / / topic editors, Alexander C. Jackson, Chen Liu, Makoto Fukuda, Michael Lazarus and Laurent Gautron |
| Autore | Laurent Gautron |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 online resource (139 pages) : illustrations; digital file(s) |
| Collana | Frontiers Research Topics |
| Soggetto topico |
Neuroanatomy
Neuroanatomy - Technique Anatomy Human Anatomy & Physiology Health & Biological Sciences |
| Soggetto non controllato |
gene delivery
mouse models tracing transgenesis morphology adeno-associated virus Fluorescent reporters neuronal circuits |
| ISBN | 9782889195138 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137218303321 |
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Laurent Gautron
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| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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