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Animal Modeling in Cancer
| Animal Modeling in Cancer |
| Autore | Korinek Vladimir |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (273 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
animal model
animal models antitumor immunity brain and nervous system cancers CALR cancer carcinoma Cdx chemical carcinogens colorectal cancer consensus molecular subtypes devitalization Drosophila drug screen epigenetics ETO-1 FLT3 ITD gene editing gene inactivation genetics hematologic malignancies IDH1/2 intestine iPSCs isoflavones JAK2 mammary tumor prevention melanoma MeLiM metaplasia mice microbiota mouse model mouse models MPL MPN (myeloproliferative neoplasms) mutation neural stem cells neurogenic niches non-mouse models NPM-1 oncogenes pre-clinical cancer model progression radiotherapy rats rodent models signaling cascades solid tumors soy sparing of neurogenic regions spontaneous regression stem cells swine thrombosis transgenic mice tumor suppressors tumorigenesis ubiquitin-proteasome system xenotransplantation zebrafish Zebrafish |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557344403321 |
Korinek Vladimir
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular and Molecular Mechanisms of Nephropathic Cystinosis
| Cellular and Molecular Mechanisms of Nephropathic Cystinosis |
| Autore | Levtchenko Elena N |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (230 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
3-dimensional models
apoptosis arterial spin labelling autophagy azoospermia biomarkers bone bone-muscle wasting CD34+ hematopoietic stem and progenitor cells cell and animal models cell model central nervous system chitotriosidase clinical course clinical trial cortical atrophy CTNS-pathogenic variants cysteamine cystine cystine blood level cystinosis disulfiram endocytosis endolysosome epithelial cell differentiation fertility fibroblast growth factor 23 fractures galectin-3 gene therapy genotype histopathology history hollow fiber membrane homeostasis hypogonadism infantile nephropathic cystinosis inflammasome interleukins investigational new drug application kidney kidney progenitors kidney proximal tubule leptin lysosomal storage disease lysosomal storage diseases lysosomal storage disorder macrophages mice mitochondrial distress mouse model nephropathic cystinosis newborn screening newborn screening for cystinosis novel therapies osteoclast osteoclasts pre-clinical studies programmed cell death proximal tubular cells sclerostin therapeutic monitoring treatment strategies for cystinosis zebrafish |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585941103321 |
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Levtchenko Elena N
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Clostridioides difficile Infection
| Clostridioides difficile Infection |
| Autore | Granata Guido |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (178 p.) |
| Soggetto topico |
Epidemiology and Medical statistics
Medicine and Nursing |
| Soggetto non controllato |
16S rRNA
anti-spore antibacterial antibiotic resistance antibiotics baicalin bovine immunoglobulins C. difficile C. difficile infection CDI CDI severity Charlson comorbidity index Child-Pugh score Clostridioides (Clostridium) difficile Clostridioides difficile Clostridioides difficile associated disease Clostridioides difficile infection Clostridium difficile co-morbidities gut dysbiosis hamsters malignancy method microbiome molecular analysis mortality mouse model multi-step algorithm multiplex "real-time" PCR n/a NAFLD nanomaterial NASH next generation sequencing nonalcoholic fatty liver disease outcome PCR capillary-based electrophoresis ribotyping peptidomimetic plasma quantification recurrent disease risk factors spore spore germination spores TcdA TcdB teicoplanin toxemia toxin toxin production triazole |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566483503321 |
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Granata Guido
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Embryo Implantation and Placental Development
| Embryo Implantation and Placental Development |
| Autore | Campagnolo Luisa |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (342 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
fetuin-A
GDM cell growth centrosome primary cilium autophagy implantation endometrium blastocyst embryo chorionic gonadotropin progesterone Notch cytokines placenta amino acid transporter mammalian target of rapamycin gestational diabetes trophectoderm cell proliferation let-7 miRNAs gene regulation fractalkine trophoblast bilaminar co-culture miRNA trophoblast cells ARID3B complex decidualization adverse pregnancy outcome preconception preimplantation genetic screening in-vitro fertilization biopsy euploid embryo pregnancy mosaicism development flow culture KIT receptor KITD816V placental development premature differentiation trophoblast stem cell trophoblast giant cell spongiotrophoblast invasion embryonic growth retardation Jag1 Dll4 endothelial cells decidua angiogenesis capillaries spiral arteries Stabilin-1 Stabilin-2 double knockout hemorrhage RNA-seq ChIP-seq enhancers transcription factors PLAGL1 tube formation blood vessel development PlGF Flt-1/VEGFR1 immune modulation human placenta lopinavir mitochondria Mfn2 UPR IRE1α placental dysfunction assisted reproduction techniques infertility preeclampsia intrauterine growth restriction trophoblast invasion sFLT-1 EGFL7 placenta-derived mesenchymal stromal cells mouse model |
| ISBN | 3-0365-5853-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639986303321 |
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Campagnolo Luisa
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Emerging Virus Infections in Adverse Pregnancy Outcomes
| Emerging Virus Infections in Adverse Pregnancy Outcomes |
| Autore | Baud David |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (182 p.) |
| Soggetto topico |
Medicine
Epidemiology & medical statistics |
| Soggetto non controllato |
Zika
congenital Zika syndrome pregnancy travelers vertical transmission fetal growth restriction COVID-19 coronavirus SARS-CoV-2 placenta transmission outcomes viruses delivery perinatal outcomes premature birth maternal complications fetus autopsy breastfeeding vaccine willingness HIV obesity obstetrics Zika virus SHIRPA microcephaly sequelae trimester mouse model maternal death angiotensin-II sFlt-1 complications neonatal health vaccination angiogenic factors endothelial dysfunction perinatal placental brain injury fetal movements neurosonography MRI troponin T |
| ISBN | 3-0365-5273-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619462503321 |
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Baud David
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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MERS-CoV
| MERS-CoV |
| Autore | Du Lanying |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (274 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
animal model
animal models authentic virus camels cell-cell fusion combination complement Coronavirus coronavirus spike glycoprotein coronaviruses correlates of immunity cross-neutralization DPP4 Drivers fusion inhibitor HCoV-229E hDPP4 HKU4 host factors inflammation lipidomics mechanism of action MERS-coronavirus MERS-CoV MERS-CoV nucleocapsid protein Middle East respiratory syndrome coronavirus Middle East Respiratory Syndrome Virus mouse model murine CD8+ T cell epitope mutation MVA vaccine n/a nanobodies neutralizing antibody neutralizing monoclonal antibodies One Health pathogenesis peptide prevention and treatment pseudotyped virus pyroptosis Qatar rabbits RBD receptor-binding domain SARS-CoV severe acute respiratory syndrome coronavirus small-molecule inhibitor spike protein spike proteins therapeutic antibodies therapeutics transmission UHPLC-MS vaccine platforms vaccines |
| ISBN | 3-03921-851-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367737603321 |
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Du Lanying
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Mechanisms of Sensorineural Hearing Loss and Development of Inner Ear Therapeutics
| Molecular Mechanisms of Sensorineural Hearing Loss and Development of Inner Ear Therapeutics |
| Autore | Vlajkovic Srdjan M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (5793 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
adenosine A1 receptor
adjunctive therapy age-related hearing loss aging astrocytes auditory brainstem brain-derived neurotrophic factor CCG-4986 chronic oral treatment circadian dysregulation clock genes cochlear nucleus cochlear rescue d-galactose deafness development gap junctions hearing loss hearing protection high-fat diet hyperbaric oxygenation hypoxic inferior colliculus inner ear intratympanic drug delivery KCNQ4 activator lateral superior olive microRNAs mitochondria dysfunction mouse model n/a neuroplasticity noise-induced cochlear injury noise-induced hearing loss nonsyndromic hearing loss otoferlin otoprotection potassium potassium voltage-gated channel subfamily q member 4 reactive oxygen species regulator of G protein signalling 4 selegiline sensorineural hearing loss sensory hair cells spontaneous activity synaptic ribbons TrkB voltage-activated calcium channel 1.3 zebrafish |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557463003321 |
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Vlajkovic Srdjan M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Insights into the Pathogenesis and Therapies of IgA Nephropathy
| New Insights into the Pathogenesis and Therapies of IgA Nephropathy |
| Autore | Suzuki Hitoshi |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (194 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
aberrantly glycosylated IgA1
adults autoantibody biomarker body mass index CD38 children clinical trials complement complement C3 crescents galactose-deficient IgA1 genetics glomerular filtration rate glycosylation of IgA1 IgA IgA nephropathy IgA Nephropathy IgA vasculitis IgA Vasculitis IgA1 immune complex kidney kidney biopsy kidney mesangium KM55 mesangial matrix expansion mouse model n/a nephritis nephrology O-glycosylation obesity Oxford score physiopathology plasma cells presentation prognosis proteinuria renal pathology treatment urinary galactose-deficient IgA1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595072403321 |
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Suzuki Hitoshi
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Biomarkers of Gastrointestinal Cancer
| Novel Biomarkers of Gastrointestinal Cancer |
| Autore | Shimura Takaya |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
colorectal cancer
advanced adenoma screening stool mRNA cancer screening cirrhosis AFP machine learning MALDI-TOF proteomics CXCR4 prognosis overall survival rectal cancer neoadjuvant chemoradiation mouse model biomarkers urokinase plasminogen activator (uPA) urokinase plasminogen activator receptor (uPAR) plasminogen activator inhibitor type 1 (PAI-1) circulating tumour cell (CTC) gastric cancer oesophageal cancer serine proteases tumour microenvironment serpins biomarker chemoresistance liquid biopsy microRNA long non-coding RNA colorectal neoplasms cancer screening tests early detection of cancer precision medicine unfolded protein hepatocellular cancer GSVA unfolded protein score epigenetic regulation genes somatic mutations molecular genetic markers extracellular vesicles microbiome 16S rRNA amplicon metagenomics liver fibrosis hepatocellular carcinoma recurrence SHG/TPEF microscopy artificial intelligence advanced gastric cancer targeted therapy urinary miRNA miR-129-1-3p miR-566 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595076103321 |
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Shimura Takaya
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pathogenesis and Therapy of Oral Carcinogenesis
| Pathogenesis and Therapy of Oral Carcinogenesis |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2023 |
| Descrizione fisica | 1 online resource (224 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
4 NQO
biomarkers cancer cancer stem cells caveolin-1 CC chemokine ligand 2 CCL2 cell polarization cholesterol cigarette smoke circulating cell-free DNA clinical trial DNA damage E2F2 EGFR epidermal growth factor receptor erlotinib extracellular matrix head and neck head and neck cancer hedgehog pathway HPV HS-173 human human papillomavirus immunocytochemistry immunohistochemistry inflammation integrin αvβ6 lymph node metastases lysyl oxidase margin mast cells MCP-1 MCs meta-analysis migration miR-125b-5p miR-155-3p miR-214-5p molecular imaging mouse model nEGFR nucleophosmin Nutri-Jelly oral cancer oral cavity oral disease oral squamous cell carcinoma oropharyngeal squamous cell carcinoma OSCC p53 pathogenesis PEITC periodontics periodontitis polymorphism PRI-724 prognosis quality of life SOD2 soluble factors squamous cell carcinoma survival synergism systematic review tertiary chemoprevention tissue factor tooth loss: oral cancer trials tumor suppressor tumour urokinase-type plasminogen activator receptor vismodegib Wnt pathway β-catenin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910743281703321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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