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Animal Modeling in Cancer
| Animal Modeling in Cancer |
| Autore | Korinek Vladimir |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (273 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
soy
isoflavones mammary tumor prevention rodent models chemical carcinogens transgenic mice Zebrafish Drosophila rats mice NPM-1 FLT3 ITD ETO-1 IDH1/2 neural stem cells brain and nervous system cancers neurogenic niches radiotherapy sparing of neurogenic regions carcinoma consensus molecular subtypes intestine oncogenes signaling cascades tumor suppressors tumorigenesis MPN (myeloproliferative neoplasms) zebrafish iPSCs JAK2 MPL CALR thrombosis ubiquitin–proteasome system cancer mouse model gene inactivation colorectal cancer mouse models microbiota antitumor immunity melanoma mutation genetics animal model swine MeLiM progression spontaneous regression devitalization metaplasia Cdx animal models epigenetics xenotransplantation drug screen pre-clinical cancer model non-mouse models gene editing stem cells solid tumors hematologic malignancies |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557344403321 |
Korinek Vladimir
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular and Molecular Mechanisms of Nephropathic Cystinosis
| Cellular and Molecular Mechanisms of Nephropathic Cystinosis |
| Autore | Levtchenko Elena N |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (230 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
cystinosis
cysteamine bone osteoclast genotype CD34+ hematopoietic stem and progenitor cells gene therapy pre-clinical studies investigational new drug application clinical trial disulfiram mice zebrafish fertility azoospermia hypogonadism histopathology mouse model lysosomal storage disease cell and animal models infantile nephropathic cystinosis bone-muscle wasting fibroblast growth factor 23 osteoclasts sclerostin leptin fractures nephropathic cystinosis hollow fiber membrane 3-dimensional models autophagy macrophages inflammasome proximal tubular cells endocytosis apoptosis chitotriosidase interleukins galectin-3 novel therapies endolysosome epithelial cell differentiation homeostasis lysosomal storage diseases mitochondrial distress kidney proximal tubule programmed cell death central nervous system cortical atrophy arterial spin labelling cystine blood level lysosomal storage disorder history treatment strategies for cystinosis newborn screening clinical course CTNS-pathogenic variants newborn screening for cystinosis kidney progenitors cell model biomarkers cystine kidney therapeutic monitoring |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585941103321 |
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Levtchenko Elena N
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Clostridioides difficile Infection
| Clostridioides difficile Infection |
| Autore | Granata Guido |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (178 p.) |
| Soggetto topico |
Medicine
Epidemiology & medical statistics |
| Soggetto non controllato |
Clostridioides difficile infection
co-morbidities mortality malignancy outcome risk factors C. difficile infection molecular analysis toxin production antibiotic resistance microbiome C. difficile hamsters bovine immunoglobulins 16S rRNA next generation sequencing Clostridioides difficile Charlson comorbidity index Child-Pugh score Clostridioides difficile associated disease CDI nonalcoholic fatty liver disease NAFLD NASH recurrent disease antibacterial Clostridioides (Clostridium) difficile peptidomimetic triazole baicalin gut dysbiosis mouse model spores anti-spore spore germination nanomaterial teicoplanin spore antibiotics multi-step algorithm multiplex "real-time" PCR PCR capillary-based electrophoresis ribotyping Clostridium difficile TcdA TcdB toxin toxemia plasma method quantification CDI severity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566483503321 |
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Granata Guido
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Embryo Implantation and Placental Development
| Embryo Implantation and Placental Development |
| Autore | Campagnolo Luisa |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (342 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
fetuin-A
GDM cell growth centrosome primary cilium autophagy implantation endometrium blastocyst embryo chorionic gonadotropin progesterone Notch cytokines placenta amino acid transporter mammalian target of rapamycin gestational diabetes trophectoderm cell proliferation let-7 miRNAs gene regulation fractalkine trophoblast bilaminar co-culture miRNA trophoblast cells ARID3B complex decidualization adverse pregnancy outcome preconception preimplantation genetic screening in-vitro fertilization biopsy euploid embryo pregnancy mosaicism development flow culture KIT receptor KITD816V placental development premature differentiation trophoblast stem cell trophoblast giant cell spongiotrophoblast invasion embryonic growth retardation Jag1 Dll4 endothelial cells decidua angiogenesis capillaries spiral arteries Stabilin-1 Stabilin-2 double knockout hemorrhage RNA-seq ChIP-seq enhancers transcription factors PLAGL1 tube formation blood vessel development PlGF Flt-1/VEGFR1 immune modulation human placenta lopinavir mitochondria Mfn2 UPR IRE1α placental dysfunction assisted reproduction techniques infertility preeclampsia intrauterine growth restriction trophoblast invasion sFLT-1 EGFL7 placenta-derived mesenchymal stromal cells mouse model |
| ISBN | 3-0365-5853-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639986303321 |
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Campagnolo Luisa
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Emerging Virus Infections in Adverse Pregnancy Outcomes
| Emerging Virus Infections in Adverse Pregnancy Outcomes |
| Autore | Baud David |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (182 p.) |
| Soggetto topico |
Medicine
Epidemiology & medical statistics |
| Soggetto non controllato |
Zika
congenital Zika syndrome pregnancy travelers vertical transmission fetal growth restriction COVID-19 coronavirus SARS-CoV-2 placenta transmission outcomes viruses delivery perinatal outcomes premature birth maternal complications fetus autopsy breastfeeding vaccine willingness HIV obesity obstetrics Zika virus SHIRPA microcephaly sequelae trimester mouse model maternal death angiotensin-II sFlt-1 complications neonatal health vaccination angiogenic factors endothelial dysfunction perinatal placental brain injury fetal movements neurosonography MRI troponin T |
| ISBN | 3-0365-5273-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619462503321 |
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Baud David
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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MERS-CoV
| MERS-CoV |
| Autore | Du Lanying |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto non controllato |
cell–cell fusion
hDPP4 n/a therapeutics animal models HCoV-229E Drivers camels rabbits SARS-CoV MERS-CoV MVA vaccine transmission RBD MERS-CoV nucleocapsid protein complement animal model pseudotyped virus combination MERS-coronavirus peptide mouse model spike protein receptor-binding domain prevention and treatment coronaviruses coronavirus spike glycoprotein therapeutic antibodies vaccine platforms mutation severe acute respiratory syndrome coronavirus pathogenesis fusion inhibitor Coronavirus murine CD8+ T cell epitope lipidomics authentic virus correlates of immunity vaccines neutralizing monoclonal antibodies Middle East respiratory syndrome coronavirus small-molecule inhibitor Middle East Respiratory Syndrome Virus DPP4 pyroptosis cross-neutralization inflammation Qatar spike proteins One Health HKU4 nanobodies mechanism of action neutralizing antibody host factors UHPLC–MS |
| ISBN | 3-03921-851-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367737603321 |
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Du Lanying
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Mechanisms of Sensorineural Hearing Loss and Development of Inner Ear Therapeutics
| Molecular Mechanisms of Sensorineural Hearing Loss and Development of Inner Ear Therapeutics |
| Autore | Vlajkovic Srdjan M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (5793 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
brain-derived neurotrophic factor
TrkB inner ear development zebrafish mitochondria dysfunction reactive oxygen species hypoxic d-galactose high-fat diet aging hearing loss astrocytes auditory brainstem lateral superior olive gap junctions voltage-activated calcium channel 1.3 otoferlin spontaneous activity deafness circadian dysregulation clock genes noise-induced hearing loss sensory hair cells synaptic ribbons sensorineural hearing loss hyperbaric oxygenation adjunctive therapy microRNAs cochlear nucleus inferior colliculus neuroplasticity noise-induced cochlear injury cochlear rescue otoprotection adenosine A1 receptor regulator of G protein signalling 4 CCG-4986 intratympanic drug delivery potassium voltage-gated channel subfamily q member 4 potassium nonsyndromic hearing loss KCNQ4 activator age-related hearing loss selegiline chronic oral treatment hearing protection mouse model |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557463003321 |
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Vlajkovic Srdjan M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Insights into the Pathogenesis and Therapies of IgA Nephropathy
| New Insights into the Pathogenesis and Therapies of IgA Nephropathy |
| Autore | Suzuki Hitoshi |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (194 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
obesity
mesangial matrix expansion body mass index IgA nephropathy IgA Vasculitis IgA Nephropathy adults children presentation physiopathology genetics prognosis treatment IgA clinical trials kidney mesangium mouse model aberrantly glycosylated IgA1 galactose-deficient IgA1 glycosylation of IgA1 biomarker complement C3 O-glycosylation IgA1 autoantibody immune complex complement kidney nephrology IgA vasculitis nephritis kidney biopsy plasma cells CD38 renal pathology urinary galactose-deficient IgA1 KM55 crescents proteinuria glomerular filtration rate Oxford score |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595072403321 |
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Suzuki Hitoshi
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Biomarkers of Gastrointestinal Cancer
| Novel Biomarkers of Gastrointestinal Cancer |
| Autore | Shimura Takaya |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
colorectal cancer
advanced adenoma screening stool mRNA cancer screening cirrhosis AFP machine learning MALDI-TOF proteomics CXCR4 prognosis overall survival rectal cancer neoadjuvant chemoradiation mouse model biomarkers urokinase plasminogen activator (uPA) urokinase plasminogen activator receptor (uPAR) plasminogen activator inhibitor type 1 (PAI-1) circulating tumour cell (CTC) gastric cancer oesophageal cancer serine proteases tumour microenvironment serpins biomarker chemoresistance liquid biopsy microRNA long non-coding RNA colorectal neoplasms cancer screening tests early detection of cancer precision medicine unfolded protein hepatocellular cancer GSVA unfolded protein score epigenetic regulation genes somatic mutations molecular genetic markers extracellular vesicles microbiome 16S rRNA amplicon metagenomics liver fibrosis hepatocellular carcinoma recurrence SHG/TPEF microscopy artificial intelligence advanced gastric cancer targeted therapy urinary miRNA miR-129-1-3p miR-566 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595076103321 |
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Shimura Takaya
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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