DNA Replication Stress |
Autore | Brosh Jr Robert M |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
Descrizione fisica | 1 electronic resource (368 p.) |
Soggetto non controllato |
Werner Syndrome
A549 cells epigenetic neurodegeneration Genome integrity adaptation cellular senescence genome instability Werner Syndrome Protein lipofuscin cell cycle checkpoints exonuclease 1 template-switching energy metabolism mutation frequency DNA replication fork regression motor neuron disease Microsatellites Alzheimer's disease chromatin remodeler repair of DNA damage AP site analogue mutagens replication timing Thermococcus eurythermalis nucleolar stress gene expression mutations spectra origin firing Fanconi Anemia superfamily 2 ATPase DNA translocation DNA repair SSB signaling homologous recombination common fragile sites 8-chloro-adenosine replication genome stability mutagenicity fork reversal multiple sclerosis non-B DNA protein stability heterogeneity ubiquitin SenTraGorTM (GL13) replication restart EdU ?-arrestin NER aging SSB end resection oxidative stress ATR dormant origins R loops DNA damage response Difficult-to-Replicate Sequences DNA double-strand repair endonuclease IV ALS double strand break repair premature aging replication stress EXO1 POL? translesion synthesis strand displacements G2-arrest DNA replication pattern SSB repair genome integrity G protein-coupled receptor kinase interacting protein 2 (GIT2) MMR replicative stress senolytics spacer interactome ATR-Chk1 DDR pathway C9orf72 replication fork restart translesion DNA synthesis DNA damage mismatch repair DNA replication stress DNA helicase Polymerase kappa DNA fiber assay H1299 cells TLS APE2 ageing cell death chromosome TopBP1 barley clock proteins post-translational modification 8-oxoG S phase ataxia telangiectasia mutated (ATM) G protein-coupled receptor (GPCR) Polymerase eta cancer G protein-coupled receptor kinase (GRK) helicase genomic instability Parkinson's disease nucleotide excision repair SupF |
ISBN | 3-03921-390-3 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910367564903321 |
Brosh Jr Robert M
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MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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Nerve disease ALS and gradual loss of muscle function : amytrophic lateral sclerosis / / Mary E. Miller |
Autore | Miller Mary E. |
Edizione | [First edition.] |
Pubbl/distr/stampa | New York, [New York] (222 East 46th Street, New York, NY 10017) : , : Momentum Press, , 2017 |
Descrizione fisica | 1 online resource (xiii, 39 pages) : illustrations |
Disciplina | 616.83 |
Collana | Human diseases and conditions collection |
Soggetto topico |
Amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis |
Soggetto genere / forma | Libros electronicos. |
Soggetto non controllato |
amyotrophic lateral sclerosis (ALS)
Lou Gehrig's disease motor neuron disease neuromuscular junction limb-onset ALS bulbar-onset ALS muscle weakness |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 1. Symptoms and diagnosis -- 2. Causes and contributing factors -- 3. Treatment and therapy -- 4. Future prospects -- Conclusion -- Bibliography -- Glossary -- About the author -- Index. |
Record Nr. | UNINA-9910136584103321 |
Miller Mary E.
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New York, [New York] (222 East 46th Street, New York, NY 10017) : , : Momentum Press, , 2017 | ||
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Lo trovi qui: Univ. Federico II | ||
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Non-Motor Symptoms in Primary Motor Neurological Disorders: from Molecular Pathways to Clinical and Therapeutic Implications |
Autore | Trojsi Francesca |
Pubbl/distr/stampa | Frontiers Media SA, 2020 |
Descrizione fisica | 1 electronic resource (130 p.) |
Soggetto topico |
Science: general issues
Neurosciences |
Soggetto non controllato |
neurodegenerative diseases
movement disorders motor neuron disease non-motor symptoms C9orf72 hexanucleotide repeat expansion neuropsychiatric disorders sleep disorders levodopa response |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Non-Motor Symptoms in Primary Motor Neurological Disorders |
Record Nr. | UNINA-9910557205803321 |
Trojsi Francesca
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Frontiers Media SA, 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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