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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (528 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
melanoma
invasion WNT5A MARCKS phosphorylation MANS peptide nanoparticles cell therapy tumor microenvironment sex/gender sex-hormones immunity microRNAs immunotherapy BRAF-mutant melanoma BRAF inhibitor mechanism of action targeted therapy tumour microenvironment plasmacytoid dendritic cells lactate dehydrogenase TLR interferon CXCL10 TPC2 HIPPO SOCE metastasis essential oils angiogenesis apoptosis uveal melanoma (UM) metastatic uveal melanoma (mUM) prognostication adjuvant therapy metastatic therapy metastatic dormancy liver-directed-therapies targeted-therapy combined therapy protein tyrosine phosphatase PTPs inhibitors melanoma immune infiltrate BRAF inhibitors microenvironment resistance therapy therapeutic resistance exosomes extracellular vesicles diagnosis prognosis ctDNA liquid biopsy prediction patient stratification BRAF arthralgia rheumatoid arthritis carbonic anhydrase hedgehog cyclopamine small molecules acetazolamide motility metalloproteinases FAK cancer mucosal melanoma nivolumab pembrolizumab ipilimumab radiotherapy cholinergic system acetylcholine muscarinic receptors nicotinic receptors melanoma metastasis ShcD adaptor protein amoeboid motility Rac1 DOCK4 melanoma PDX target therapy cancer stem cells slow cycling phenotype drug resistance OXPHOS lipid metabolism cancer associated fibroblast melanomagenesis biomarkers checkpoint inhibitor PD-1 melanoma markers cytokines machine learning Support Vector Machine principal component analysis BCL2L10 STAT3 cytotoxicity survival ABT-737 Bcl-2 family ML258 HuR MITF metastases siRNA |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in the Biology of Phototrophic Bacteria
| Advances in the Biology of Phototrophic Bacteria |
| Autore | Imhoff Johannes F |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
phylogeny
photosynthetic reaction center proteins bacteriochlorophyll biosynthesis phototrophic purple bacteria evolution of anoxygenic photosynthesis iron-sulfur cluster isc genes suf genes antisense promoters OxyR IscR Irr anoxygenic phototrophic bacteria purple nonsulfur bacteria massive blooms pufM gene Rhodovulum phylogenomics bioerosion anoxygenic phototroph microbiome euendolith Rhodobacter capsulatus Rhodobacter sphaeroides photooxidative stress transcriptomics proteomics stress defense heliobacteria Heliorestis convoluta alkaliphilic bacteria soda lake bacteriochlorophyll g biological soil crust drylands niche partitioning nitrogen fixing cyanobacteria Alphaproteobacteria Rhodobacteraceae nitric oxide quorum sensing gene transfer agent motility Crp/Fnr Dnr RegA ChpT green sulfur bacteria syntrophy e-pili adhesion protein photosynthetic symbionts large multiheme cytochrome metagenomic binning genomes of photosynthetic bacteria glycine betaine biosynthesis ectoine biosynthesis osmotic adaptation phylogeny of osmolyte biosynthesis filamentous anoxygenic phototroph microbial mats hot springs metatranscriptomics energy metabolism carbon fixation aerobic anoxygenic phototrophic bacteria bacteriochlorophyll a photosynthesis genes rhodopsin Sphingomonadaceae aerobic anoxygenic phototrophs siderophore metallophore CAS assay Chromocurvus halotolerans strain EG19 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557401903321 |
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Imhoff Johannes F
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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AMP-Activated Protein Kinase Signalling
| AMP-Activated Protein Kinase Signalling |
| Autore | Neumann Dietbert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (452 p.) |
| Soggetto non controllato |
HDACs
transcription epigenetics spermatozoa par complex A769662 MDCK skeletal muscle AID phosphorylation energy metabolism monocytes autophagy CML liver hindlimb suspension pregnancy preeclampsia gestational diabetes mellitus CaMKK2 assisted reproduction techniques nutrient-sensing signals sonic hedgehog protein acetylation glycogen storage disease AMPK adenosine monophosphate-activated protein kinase AICAR indirect calorimetry IL-1? MyHC I(?) HDAC4/5 endothelial cells infection hepatocyte p70S6K lipid metabolism host defense exercise kidney disease heat shock protein ?RIM mycobacteria activation loop developmental origins of health and disease (DOHaD) CREB TAK1 metabolic-inflammation phenylephrine AMP-activated protein kinase (AMPK) KATs 2-methoxyestradiol DNA methylation NLRP3 pump ?-linker steatosis AMPK kinase stress endothelial nitric-oxide synthase vasodilation adherent junctions epithelial cells glycogen Akt synaptic activation cellular energy sensing glucose uptake transporter co-expression atrophy nutrigenomics motility vasoconstriction fatty acid oxidation oxidative stress AS160 membrane histone modification sirtuin 1 (SIRT1) chromatin remodeling insulin signalling dietary fatty acids ULK CMML adaptive thermogenesis mTOR MDS mechanical unloading AML endothelial function medulloblastoma PKA adipose tissue NAD+ membranes nutrition ZO-1 TBC1D4 adipocyte soluble Adenylyl cyclase metabolism renin-angiotensin system energy utilization proteasome differentiation signaling peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) hypertrophy AMP-activated protein kinase metabolic disease LKB1 soleus muscle macrophages Immediate early genes CBS benign motor endplate remodeling ionomycin nectin-afadin tight junctions resveratrol protein kinase B regrowth mitochondria protein synthesis energy deficiency catechol-O-methyltransferase fiber-type microarrays carrier acetyl-CoA hypertension 3T3-L1 hypothalamus food intake |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346858503321 |
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Neumann Dietbert
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Gastrointestinal Tract Disorders
| Gastrointestinal Tract Disorders |
| Autore | Durazzo Marilena |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (236 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
Crohn's disease
ulcerative colitis biologics anemia gastroesophageal reflux cough asthma laryngo-pharyngeal reflux chest pain tooth erosions inflammatory bowel diseases sleep disorders sleep medicine PPI diverticulosis diverticulitis risk factors Marfan's syndrome diverticula abdominal symptoms ultrasound infant food allergy fecal biomarkers tumor necrosis factor α eosinophil derived neurotoxin calprotectin Emorsan®Gel hemorrhoidal disease hemorrhoidectomy pain wound healing chronic idiopathic constipation constipation irritable bowel syndrome pathophysiology primary care medical students public health social media dietary habit pandemic dyspepsia diabetes gastroparesis inflammatory bowel disease SCORE carotid plaques cardiovascular risk dyssynergic defecation slow transit constipation motility colonic transit anorectal manometry gastrointestinal disorders endoscopic vacuum therapy etiology transmural defect upper gastrointestinal tract Helicobacter pylori eradication antibiotic resistance tailored empirical gastrointestinal bleeding new oral anticoagulants vitamin K antagonist rebleeding chronic gastritis peptic ulcer disease gastric cancer MALT-lymphoma therapy vaccines DA-9701 diabetic mouse model functional dyspepsia diabetic gastroparesis STZ gastrointestinal motility human leukocyte antigen celiac disease autoimmune hepatitis primary sclerosing cholangitis primary biliary cholangitis autoimmune pancreatitis IgG4-related sclerosing cholangitis IgG4-related hepatopathy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566471703321 |
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Durazzo Marilena
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine-Derived Products for Biomedicine
| Marine-Derived Products for Biomedicine |
| Autore | Giovine Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (214 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
Extracellular Polymeric Substances
hydrogel mesenchymal stem cells biomaterials enzyme omega 3 PUFA Trichormus variabilis Cyanobacteria mechanochemical synthesis chitosan laser stereolithography long-term stability scaffold tissue reaction chitin scaffolds biological materials demosponges Pseudoceratina arabica microalgae biodiversity bioactive compounds green extractions pharmaceutical secondary metabolites biofuels antibiofilm fucoidan motility nanoparticles Pseudomonas aeruginosa virulence factors n-3 fatty acids brain α-Chitin prodigiosin anti-tumors Serratia marcescens bioprocessing echinochrome A estradiol extracellular matrix vocal fold ovariectomy marine polymers ionic liquids tissue engineering membranes hydrogels sponges Chondrosin Chondrosia reniformis marine toxin cytotoxic protein Porifera marine microbes cancer prevention therapy in vitro in vivo clinical studies |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557103303321 |
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Giovine Marco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Microbial Virulence Factors
| Microbial Virulence Factors |
| Autore | Leitão Jorge H |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (400 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Aeromonas hydrophila
LysR-family ΔlahS global regulator virulence Sclerotinia sclerotiorum SsNsd1 compound appressorium two-dimensional electrophoresis proteomics analysis differential expression proteins cystic fibrosis Pseudomonas aeruginosa Burkholderia cepacia complex small noncoding regulatory RNAs pathogenicity usg truA Salmonella enterica serovar Typhimurium oxidative stress intracellular survival pathogenomics coagulase-negative staphylococci virulence factors whole genome sequencing autotransporter covalent labeling bacterial surface protein SpyCatcher topology mapping virulence factor Candida host-pathogen interaction biofilm formation morphology immune evasion Trueperella pyogenes pyolysin infection immune response Actinomycetales Bordetella pertussis Hfq omics analysis T3SS serum resistance solute-binding proteins phytoplasma effector protein apple apple proliferation bacteria blood–brain barrier blood–cerebrospinal fluid barrier meningitis outer membrane vesicles (OMVs) Candida albicans antimicrobial peptides complement interspecies interactions inter-kingdom protection fungicidal activity fluconazole hyphae antimicrobial peptide EDTA primary ciliary dyskinesia anti-virulence sputum chronic infection Enterobacterales Klebsiella Enterobacter Citrobacter antibiotic resistance biofilm SPATEs UTIs cytotoxicity serine proteases 5637 bladder cells mucin gelatin actin protease Lon Dickeya solani plant pathogen motility type III secretion system resistance to stress lon expression pectinolytic enzymes gene expression manipulation inflammation persistence replicative niche actin proteolysis metalloproteinases protease ECP 32 grimelysin protealysin bacterial invasion microbial virulence factors bacterial pathogens fungal pathogens |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557746603321 |
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Leitão Jorge H
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neurogenic Bowel Dysfunction
| Neurogenic Bowel Dysfunction |
| Autore | Krogh Klaus |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (242 p.) |
| Soggetto topico |
Medicine
Neurology & clinical neurophysiology |
| Soggetto non controllato |
laxatives
constipation adults prevalence utilisation gut microbiota spina bifida transanal irrigation urinary tract infection SCI MENTOR NBD fecal incontinence Parkinson’s disease autonomic gastrointestinal alpha-synuclein parasympathetic neurogenic bowel dysfunction low anterior resection syndrome faecal incontinence chronic constipation bowel dysfunction quality of life spinal cord injury multiple sclerosis pharmacological systematic review neurogenic bowel treatment assessment bowel function exoskeletal walking difficulty with evacuation neostigmine glycopyrrolate iontophoresis autonomic dysfunction motility investigations manometry breath test imaging diabetes mellitus postprandial hypotension food ingestion ambulatory blood pressure measurement cohort study pediatric children adolescent anorectal malformation cerebral palsy acute rehabilitation opioids SCI bowel management |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585944903321 |
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Krogh Klaus
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutrition, Microbiota and Noncommunicable Diseases
| Nutrition, Microbiota and Noncommunicable Diseases |
| Autore | Plaza-Díaz Julio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
sperm quality
probiotics zebrafish motility behavior intestinal microbiota intestinal Bacteroides cardiorespiratory fitness trunk muscle training aerobic exercise training brisk walking nutrients gut microbiota nutrition habitual diets Western diet obesity cardiometabolic risk factors chronic health conditions gastrointestinal disorders prebiotics and probiotics metabolic syndrome gastrointestinal microbiome Lactobacillus reuteri V3401 sugar alcohol prebiotic bowel function immune function respiratory tract infections otitis media sinusitis weight management satiety bone health AMP-activated protein kinase butyrate developmental origins of health and disease (DOHaD) high fat diet hypertension nutrient-sensing signals propionate short chain fatty acids kefir autism spectrum disorders oral microbiota dysbiosis co-occurring conditions allergy abdominal pain biomarker discovery anorexia food restriction ClpB microbiota Enterobacteriaceae inulin circadian rhythm feeding timing choline trimethylamine trimethylamine n-oxide 16S rRNA gene profiling qPCR linear mixed models soy protein lipid metabolism circadian chrono-nutrition microbiome pregnancy fetus placenta newborn infancy critical illness sepsis lipid metabolome amlodipine corticosterone ACTH gut bacteriome ischemia-reperfusion injury nutritional status supplemented nutrition partial hepatectomy liver transplantation vaginal microbiome bacterial communities vaginal dysbiosis bacterial vaginosis risk factors hormone replacement therapy cardiovascular diseases atherosclerosis prebiotics alanine aminotransferase antibiotic Optifast gut microbiome metronidazole nonnutritive sweeteners sweetening agents |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557484203321 |
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Plaza-Díaz Julio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances in Pancreatic Neoplasms
| Recent Advances in Pancreatic Neoplasms |
| Autore | Sperti Cosimo |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (176 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
PIWI proteins
PIWIL3 PIWIL4 pancreatic cancer EMT chemoresistance motility HNF4A survival pancreatic neuroendocrine neoplasm primary pancreatic carcinoid serotonin-secreting pancreatic tumour serotonin-producing pancreatic tumour neoadjuvant chemotherapy response carbohydrate antigen 19-9 fluorodeoxyglucose pancreatectomy positron emission tomography prognosis standardized uptake value Pancreatic ductal adenocarcinoma microRNAs pancreatic fistula pancreatic neoplasm renal cell carcinoma pancreatic neoplasms PET-CT scan pancreatic ductal adenocarcinoma pancreatic cancer prognosis completion total pancreatectomy pooled analysis recurrent pancreatic cancer repeated pancreatectomy pancreas neuropathy taxanes biomarker C-reactive protein to albumin ratio inflammation intraductal papillary mucinous neoplasm modified Glasgow prognostic score neutrophyl lymphocite ratio platelet-to-lymphocyte ratio robotic pancreatic surgery pancreato-gastrostomy low muscle mass sarcopenia pancreatic adenocarcinoma pancreatic surgery body composition |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566480103321 |
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Sperti Cosimo
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of Extracellular Matrix in Cancer Development and Progression
| The Role of Extracellular Matrix in Cancer Development and Progression |
| Autore | Tzanakakis George |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (182 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
elastin
ribosomal protein SA tongue carcinoma MMP-2 EGCG pancreatic ductal adenocarcinoma syndecans proteoglycans tumor progression angiogenesis syndecan-4 heparan sulfate cancer prognosis biomarker signal transduction proteoglycan metastasis extracellular matrix fibrosis immune cell modulation neutrophils neutrophil extracellular trap macrophages BCC MMP TIMP invasion lumican cancer cell growth motility hyaluronan RHAMM CD44 wound repair breast cancer malignant pleural mesothelioma pleural effusion extracellular vesicles biomarkers sulfated hyaluronan estrogen receptors epithelial-to-mesenchymal transition matrix metalloproteinases |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566470803321 |
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Tzanakakis George
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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