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Celebrating 120 Years of Butantan Institute Contributions for Toxinology
| Celebrating 120 Years of Butantan Institute Contributions for Toxinology |
| Autore | Moura-Da-Silva Ana Maria |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (408 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
mass spectrometry
proteome snake venom Bothrops jararaca breast cancer HF3 human plasma proteolysis snake venom metalloproteinase Bothrops atrox blister local damage DAMPs antivenom snakebite Bothrops metalloproteases inflammation microcirculation adhesion molecules leukocyte-endothelium interactions individual variability venom heterogeneity STEC Stx2 antibody fragment monoclonal antibody neurodegenerative disease neurodegeneration IL-17 glial cells crotoxin epithelial-mesenchymal transition spheroid model tumor stroma Lonomia envenoming innovation Tityus serrulatus venom components hypotensins NEP inhibition cytokines toxins venoms skin secretion drug discovery scorpion accidents lactation maternal care seizure threshold leech Haementeria vizottoi cysteine proteases inhibitor recombinant cystatin cathepsin L Cryptops iheringi centipede venom toxin transcriptome recombinant protein venomics chilopoda oral tolerance ELISA Bothrops phospholipases A2 lipid mediators signaling pathways fish venoms cytolysins multifunctionality pore formation Bitis arietans venom (BaV) Kn-Ba cytokines and chemokines PGE2 THP-1 macrophages analgesic peptide protein kinase C hyperalgesia cell-signaling Hyalomma dromedarii salivary glands serpin anticoagulants thrombin inhibitor β-defensins snakes antimicrobial activity bioisosterism peptides Thalassophryne nattectin reverse-phase HPLC MALDI-ToF hemagglutinating activity antibacterial activity toxinology animal toxins |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674030303321 |
Moura-Da-Silva Ana Maria
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cyanobacteria and Cyanotoxins: New Advances and Future Challenges
| Cyanobacteria and Cyanotoxins: New Advances and Future Challenges |
| Autore | Cameán Ana M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (246 p.) |
| Soggetto non controllato |
method validation
sirtuin 1 (SIRT1) arctic Cylindrospermopsin Microcystin-LR 16S rRNA gene astaxanthin secondary metabolites shotgun metagenomic sequencing time-resolved fluoroimmunoassay Histopathological evaluation cyanobacterial thresholds akinetes nutrient enrichment benthic mats cylindrospermopsin drinking water treatment plant blue-green algae supplements lettuce genotoxicity exposure bacterial community PCR microcystin-LR marine natural compounds ELISA [d-Leu1]Microcystin-LR Paracentrotus lividus tadpoles apoptosis 16S rRNA gene sequencing PSP toxins marine cyanobacteria hemolytic essay energy budget bioassays anatoxin-a Lithobates catesbeianus mixture reproductive toxicity cyanobacteria taste-and-odor compounds Procambarus clarkii drinking water saxitoxin resveratrol harmful algal blooms cytotoxicity phylogenetic analyses Yangtze estuary microcystin mutagenicity detection Artemia salina water source cyanotoxins microcystins in vitro marine sponges microcystin-LR (MC-LR) UPLC-MS/MS reservoir microbial metabolisms Aphanizomenon flos-aquae monoclonal antibody oxidative stress Nostocales |
| ISBN | 3-03921-839-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cyanobacteria and Cyanotoxins |
| Record Nr. | UNINA-9910404089003321 |
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Cameán Ana M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor
| Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor |
| Autore | Holzmann Klaus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (276 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
FGFR4
FGF19 gene regulation cancer signaling anticancer FRS2 FGFR NVP-BGJ398 LY2874455 sarcoma cancer-associated fibroblasts GPER breast cancer estrogen FGFR1 FGF2 optogenetics ERK AKT receptor kinase neurite outgrowth HEK293 PC12 fibroblast growth factor receptors signaling receptor cross-talk coreceptor membrane proteins FGFR2 ERK1/2 phosphorylation serine negative feedback loop cancer prognosis HCC inhibitors FGF fibroblast growth factor autocrine signaling skin melanoma squamous and basal cell carcinoma seborrheic keratosis targeted therapy resistance structure kinase inhibitor gastric cancer monoclonal antibody small molecule FGFR2c autophagy keratinocyte MTOR JNK1 review malignant glioma brain cancer astrocytoma Sprouty proteins FGF-mediated signaling tumor suppressor tumor promoter malignant pleural mesothelioma overall survival immunohistochemistry infigratinib sensitivity FGF8 FGF18 adenocarcinoma of the esophagogastric junction neoadjuvant therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Fibroblast Growth Factor Receptor |
| Record Nr. | UNINA-9910557898903321 |
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Holzmann Klaus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy
| Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy |
| Autore | Ruvo Menotti |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (278 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
porcine deltacoronavirus
nucleocapsid monoclonal antibodies neurodegenerative disorders affibody molecules blood–brain barrier receptor-mediated transcytosis transferrin receptor AL amyloidosis CD38 anti-CD38 MoAb Daratumumab Isatuximab myeloma BCMA bispecific T-cell engager antibody-drug conjugates chimeric antigen receptor T-cells belantamab mafodotin idecabtagene vicleucel JNJ-68284528 Mabs Antibody-Drug Conjugate cancer therapy drug targeting payload cross-linking antibody fragment Fab scFv E. coli YKL-40 CHI3L1 monoclonal antibody phage display lung metastasis prostate-specific membrane antigen in vivo imaging prostate cancer glutamate carboxypeptidase II NAALADase immunization antibody protocol guinea pig cDNA chimeric antigen receptor (CAR T) universal CAR T modular CAR T universal immune receptor CAR adaptor adoptive immunotherapy split CAR bispecific polyspecificity pharmacokinetics solubility aggregation viscosity developability stability affinity specificity protein engineering self-association non-specific binding immunogenicity antibody fragments single chain amyloid oligomer neurotoxicity NUsc1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557613003321 |
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Ruvo Menotti
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0
| Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0 |
| Autore | Ruvo Menotti |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (112 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
PRAME
mAb bio-layer interferometry epitope identification monoclonal antibody free radical protein aggregation oxidation excipient foot-and-mouth disease virus type O type A phage display antibody competitive ELISA atherosclerosis nano-emulsion magnetic resonance imaging stealth human antibody C. auris candidiasis multidrug resistance monoclonal antibodies universal antibodies cell wall passive immunization cell-based panning semi-automated cell panning FGFR3-specific antibody |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557615103321 |
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Ruvo Menotti
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances in Antibody Therapeutics
| Recent Advances in Antibody Therapeutics |
| Autore | Heo Yong-Seok |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
interleukin 33
ST2 receptor scFv C2_2E12 bladder cancer antibodies immune checkpoint inhibitors antibody-drug conjugates sacituzumab govitecan enfortumab vedotin erdafitinib cost-effectiveness G protein-coupled receptor membrane protein antigen therapeutic antibody anti-angiogenesis delta-like ligand irinotecan paclitaxel VEGF SARS-CoV-2 spike protein receptor-binding domain phage display monoclonal antibody cytomegalovirus peptide/major histocompatibility complex class I complex T-cell-receptor-like antibody affinity maturation yeast surface display combinatorial antibody library agonist antibody cell fate bispecific antibodies bioassays mechanisms of action binding assays potency assays atherosclerosis inflammation antibody therapy blood-brain barrier antibody pharmacokinetics disposition biochemical and physicochemical properties Fc binding receptor-mediated transcytosis brain shuttle molecular Trojan horse transferrin anti-cancer antibody antibody engineering biophysical properties computational methods research cell bank antibody therapeutics recombinant antibodies intracellular antibodies single-chain antibody fragment nanobody Human papillomaviruses HPV oncoproteins HPV-associated cancer HPV cancer therapy asthma refractory asthma biomarker |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580204803321 |
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Heo Yong-Seok
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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