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Advances in Multiple Sclerosis Research-Series I
| Advances in Multiple Sclerosis Research-Series I |
| Autore | Matsoukas John |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (334 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adult-onset
agonist peptide alemtuzumab altered peptide ligands antibodies against GluR3 peptide antibody detection antigen-specific immunotherapies antigen-specific immunotherapy astrocytes autoimmune diseases autoimmune encephalitis autoimmunity B cell receptor biomarker bupropion carriers cellular immunity central nervous system cerebral blood flow chloroquine clinical outcome clinical outcomes clinical phenotype cognitive impairment conformational analysis conjugation cranial nerve-VI palsy craniopharyngioma delivery methods dendritic cells diagnosis diagnostic markers disease-modifying treatments drug delivery nanosystems EAE early-onset ELISA experimental autoimmune encephalomyelitis fampridine fractionated stereotactic radiation treatments free light chains Graphite/SiO2 electrode gut microbiome gut-brain axis HPLC Human Leucocyte Antigens immune modulation immune thrombocytopenic purpura immunogenetics immunoglobulins immunomodulation immunotherapeutics immunotherapy inflammation intracortical facilitation kappa lipids major depression mannan MBP83-99 peptide memory T cells metagenomics microglia MOG35-55 molecular dynamic monoclonal antibodies MS MS drugs multiple sclerosis Multiple Sclerosis multivalency myelin basic protei myelin oligodendrocyte glycoprotein myelin peptides N-glucosylated peptide epitopes nanoparticles nanotechnology neurodegeneration neuroimaging neuropsychological assessment NMR spectroscopy NOE-constraints oligodendrocytes oxidative peptide peptides plasma exchange polymers positron emission tomography probiotics proteolipid protein S-adenosylmethionine sample size short intracortical inhibition sphenoid sinusitis ST285 Streptococcus thermophilus T cell receptor tDCS tetraspanins therapeutics tolerance tolerance induction tolerogenic vaccines trimolecular complex TSPAN32 vaccine vaccines vitamin D3 voltammetry walking disability yoga |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557385403321 |
Matsoukas John
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing
| Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing |
| Autore | Pörtner Ralf |
| Descrizione fisica | 1 online resource (226 p.) |
| Soggetto topico |
History of engineering and technology
Technology: general issues |
| Soggetto non controllato |
Adeno-associated virus
Bayes optimization biopharmaceutical manufacturing bioprocess bioreactor bioreactor characterization biosensor biotherapeutics production cell culture cell culture model Chinese hamster ovary cells CHO DP-12 clonal cell population computational fluid dynamics continuous critical shear stress cryopreservation diabetes Escherichia coli Gaussian processes gene therapy hybrid modeling hydrodynamic gradients hydrodynamic stress inoculum train Kolmogorov length scale machine learning microcarriers model-assisted DoE monitoring monoclonal antibodies multi-objective n/a N−1 perfusion operational space Pareto optimization PAT PEI phenotypic diversity process analytical technology (PAT) process development process intensification quality by design quality by design (QbD) seed train sensors shear stress-guided production smart biomanufacturing soft-sensor spectroscopy spheroid strength surface plasmon resonance (SPR) transfection transient expression uncertainty-based upstream bioprocessing upstream processing vaccines production β-cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595072803321 |
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Pörtner Ralf
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| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Nanomedicine
| Cancer Nanomedicine |
| Autore | Hoskins Clare |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (510 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
actin
active targeting acute toxicity adsorption albumin albumin nanoparticle albumin nanoparticles anacardic acid angiogenesis anti-cancer anti-metastatic enzyme cancer therapy anti-topoisomerase activity anti-tumor immunity antibody drug conjugate (ADC) anticancer and antibacterial activity antitumor strategy apoptosis ascorbic acid BALB-neuT mice biodistribution biomimetic biomimetic core-shell nanoparticles biomimicry bleeding blood brain barrier brain tumours breast cancer cabazitaxel cancer cancer diagnosis cancer nanomedicine cancer therapy cathepsin D cathepsin L cats cell signaling cellular interaction cellular microenvironment chemico-physical functionalization chemotherapeutics chirality separation clinical status clinical translation collagen colloidal stability colorectal carcinoma combinatorial therapy copper CPMV CSCs cyclodextrins cytotoxicity diagnostics differentiated neuroblastoma dioleoylphosphatidylethanolamine DNA origami docetaxel dogs DOX doxorubicin drug combination drug delivery drug delivery system drug-gene delivery drug-in-cyclodextrin-in-liposome dual-targeting epithelial-to-mesenchymal transition EPR effect erlotinib everolimus exosomes extracellular vesicles FA-DABA-SMA flow folate folate receptor folic receptor alpha glioblastoma glioma gold nanoparticles gold nanorods graphene oxide hepatocellular carcinoma hyaluronic acid hyaluronidase hybrid nanoparticles hyperthermia hyperthermia therapy hypoxia imaging immune modulation immunosuppression immunotherapy Immunotherapy in situ vaccine in vitro in vitro anti-cancer activity integrin intra-arterial chemotherapy intracellular disruption intracranial glioma iron affinity lanthanide metal ligand lipid nanoparticles liposome liposomes loading lung cancer lymphadenectomy magnetic actuation magnetic drug targeting magnetic hyperthermia magnetic nanoparticles magnetic nanowires magnetic silica-coated iron oxide nanochains magnetometer mammary carcinoma mangiferin MDA-MB-231 melanoma membrane-wrapped mesenchymal stem cells (MSCs) Mesoporous silica nanoparticle mesoporous silica nanoparticles metabolism microbubble microfluidic mitoxantrone mixed micelle molecular imaging monoclonal antibodies multicellular tumor spheroids nano-bio interactions nano-engineered MSCs nanobiotechnology nanocarrier nanomedicine nanomedicines nanomicelles nanoparticle nanoparticles nanostructured lipid carrier nanosystems nanotechnology: bioengineering nanotherapeutics NASH near IR hyperspectral imaging NK cell-derived exosomes oncogenes oncogenic proteins organoids organotin orthotopic lung tumor model osteopontin ovarian cancer ovarian carcinomatosis oxidation-sensitive release paclitaxel pancreatic cancer parvifloron D passive targeting PD-L1 PEGylation peptidomimetics pH responsive photodynamic therapy photodynamic therapy article photothermal therapy photothermal treatment plasmonic photothermal therapy plasmonics platelet membrane PLGA poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer polydopamine nanoparticles polymeric nanoconstruct polymeric nanoparticles prostate cancer radiotherapy real-time quantitative polymerase chain reaction (qPCR) remote loading RGD peptide riboflavin secondary structure self-assembly sentinel lymph node dissection shear stress single-walled carbon nanotubes siRNA size SN38 spheroids SPION stimuli-responsive superparamagnetic iron oxide nanoparticles surgery target treatment targeted delivery targeted delivery system targeted drug delivery targeted therapy TAT peptide temoporfin theranostic nanomaterials theranostics therapeutics titanate nanotubes translational medicine triple negative breast cancer tumor microenvironment tumor spheroid disruption tumor targeting tumor vectorization tumour microenvironment tumour targeting ultrasound vectorization VEGF verteporfin viral nanoparticles vitamin B2 VX2 tumor Vδ2 T cells yet reasonably common within the subject discipline zoledronic acid β-cyclodextrin nanosponges |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557114703321 |
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Hoskins Clare
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Characterization of Antibody Responses to Virus Infections in Humans
| Characterization of Antibody Responses to Virus Infections in Humans |
| Autore | Ilinykh Philipp |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (142 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
antibody
antibody specificity antibody therapeutic chemiluminescent immunoassay (CLIA) China coronavirus disease 2019 COVID-19 cryo-EM cytokine profile diagnostic test ebolavirus ELISA filovirus filoviruses full proteome glycan microarrays Guangdong H5N6 (clade 2.3.4.4) highly pathogenic avian influenza virus human sera IgA IgG IgM longitudinal antibody response marburgvirus monoclonal antibodies n/a neutralising antibodies neutralization assay neutralization efficacy peptide microarrays post-infection post-vaccination recombinant proteins SARS-CoV-2 seroprevalence serum antibody structural biology varicella-zoster virus (VZV) viral persistence virus neutralization X-ray crystallography |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580206803321 |
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Ilinykh Philipp
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug-Drug Interactions
| Drug-Drug Interactions |
| Autore | Kim Dong Hyun |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (242 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
(‒)-sophoranone
1A2 2B6 2C19 2C8 2C9 2D6 3A4 ADME adverse drug reactions biflavonoid chronic kidney disease competitive inhibition computational prediction CYP CYP1A1 CYP1A2 CYP2C9 CYP2D6 CYP3A CYP3A4 cytochrome P450 cytochromes P450 DDI Dexamethasone drug interaction drug interactions drug metabolism drug transporter drug-drug interaction drug-drug interactions expression fexofenadine gepants high plasma protein binding in silico in vitro in vivo inhibitor ixazomib Ketoconazole lasmiditan Lexicomp low permeability Loxoprofen mechanism-based inhibition metabolic DDI metabolism migraine monoclonal antibodies non-competitive inhibition O-desmethyltramadol OATP1B1 OATP1B3 organic anion transporting polypeptide 1A2 (OATP1A2) P-glycoprotein (P-gp) P450 pharmacokinetics physiologically-based pharmacokinetics plasma concentration polypharmacy potent inhibition QSAR regulation Rumex acetosa selamariscina A signal detection algorithms spontaneous reporting systems subset analysis substrate systemic exposure tadalafil ticagrelor tissue-specific tramadol tyrosine kinase inhibitors ubiquitination uridine 5'-diphosphoglucuronosyl transferase |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557666403321 |
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Kim Dong Hyun
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Food Allergies in Modern Life
| Food Allergies in Modern Life |
| Autore | Manti Sara |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (202 p.) |
| Soggetto topico |
Biology, life sciences
Food & society Research & information: general |
| Soggetto non controllato |
adolescents
adults alginate allergen allergen-specific lymphocyte stimulation test allergy almond almond allergens atopy patch test biologics Caco-2/Immune cells co-culture children clinical score CMA component-resolved diagnostics Cor a 1 Cor a 14 Cor a 9 cow's milk allergy cross-reaction cytokine endoscopy environmental factors eosinophilic esophagitis eosinophilic gastrointestinal disorders failure to thrive fecal biomarkers flour food allergy functional abdominal pain disorders functional dyspepsia GER GERD Gly m 4 growth hazelnut hydrolyzed formula hypersensitivity IgE IgG and IgG4 individualized diagnostics infants irritable bowel syndrome ISAC legumes lipid transfer protein lupine malnutrition monoclonal antibodies non-IgE gastrointestinal food allergy nsLTP nut nutrition obesity oral food challenge peach peanut plant-food allergy primary prevention profilin Pru p 3 reflux Rosaceae fruit sensitization thickened formula undernutrition vitamin |
| ISBN | 3-0365-5168-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619468103321 |
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Manti Sara
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Improved Analytical Technologies for the Detection of Natural Toxins and Their Metabolites in Food
| Improved Analytical Technologies for the Detection of Natural Toxins and Their Metabolites in Food |
| Autore | Lattanzio Veronica Maria Teresa |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (156 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
absorbance data
Aflatoxin M1 amanitins amatoxins antibodies antibody aptamers biological sample brevetoxins CBA-N2a ciguatoxins citreoviridin death cap mushrooms electrochemical biosensors ELISA Heliotropium amplexicaule herbs honey immunoassay indicine lateral flow immunoassay LC-MS LC-MS/MS lycopsamine matrix effects method validation microbial toxin detection milk monoclonal antibodies mushroom poisoning n/a oleandrin Parsonsia straminea plant toxins point-of-care pyrrolizidine alkaloid rice saxitoxins seafood safety standardization strip test immunoassay two dimensional layered nanomaterials urine validation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557298603321 |
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Lattanzio Veronica Maria Teresa
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy
| Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy |
| Autore | Ruvo Menotti |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (278 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
adoptive immunotherapy
affibody molecules affinity aggregation AL amyloidosis amyloid anti-CD38 MoAb antibody antibody fragment antibody fragments Antibody-Drug Conjugate antibody-drug conjugates BCMA belantamab mafodotin bispecific bispecific T-cell engager blood-brain barrier cancer therapy CAR adaptor CD38 cDNA CHI3L1 chimeric antigen receptor (CAR T) chimeric antigen receptor T-cells cross-linking Daratumumab developability drug targeting E. coli Fab glutamate carboxypeptidase II guinea pig idecabtagene vicleucel immunization immunogenicity in vivo imaging Isatuximab JNJ-68284528 lung metastasis Mabs modular CAR T monoclonal antibodies monoclonal antibody myeloma NAALADase neurodegenerative disorders neurotoxicity non-specific binding nucleocapsid NUsc1 oligomer payload phage display pharmacokinetics polyspecificity porcine deltacoronavirus prostate cancer prostate-specific membrane antigen protein engineering protocol receptor-mediated transcytosis scFv self-association single chain solubility specificity split CAR stability transferrin receptor universal CAR T universal immune receptor viscosity YKL-40 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557613003321 |
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Ruvo Menotti
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0
| Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0 |
| Autore | Ruvo Menotti |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (112 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
antibody
atherosclerosis bio-layer interferometry C. auris candidiasis cell wall cell-based panning competitive ELISA epitope identification excipient FGFR3-specific antibody foot-and-mouth disease virus free radical human antibody mAb magnetic resonance imaging monoclonal antibodies monoclonal antibody multidrug resistance nano-emulsion oxidation passive immunization phage display PRAME protein aggregation semi-automated cell panning stealth type A type O universal antibodies |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557615103321 |
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Ruvo Menotti
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Advances on Zika Virus Research
| New Advances on Zika Virus Research |
| Autore | Martinez-Sobrido Luis |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (552 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
Aedes aegypti
African-lineage anti-viral immunity antiviral antiviral compounds antiviral responses antivirals apoptosis arbovirus Asian lineage Asian-lineage assay standardization astrocytomas bacterial artificial chromosome Bacterial artificial chromosome Bayesian analyses blood-retinal barrier boolean logic-processing nucleic acid probes cell surface receptors chimeric viruses clinical trials congenital Zika syndrome cross-reactions cryptic promoter silencing cytopathic effects dengue virus dengue viruses detoxification and immune system responses diagnosis dsRNA eIF4A ELISA emerging arbovirus EQA external quality assessment eye fetal infection flavivirus flaviviruses FSS13025 Full-length cDNA infectious clones full-length molecular clone gene expression genetic variability heme-oxygenase 1 hepatocytes host genetic variation host-directed antivirals human brain glial cells IgA IgG avidity tests immune response indirect immunofluorescence infection infectious cDNA infectious clone infectious RNA innate response insecticide resistance isothermal nucleic acid amplification laboratory preparedness microcephaly microglia cells microRNAs microsphere immunoassay molecular diagnostics monoclonal antibodies mosquito mosquito surveillance mosquito-borne flavivirus MR766 multiplex nucleic acid detection mutagenesis natural history neural cells neural progenitor cells neuroinflammation neurons neuropathogenesis NHP Non-human primates NS1 protein NS2A protein NS5 nucleic acid computation nucleic acid strand exchange ocular optimised outbreak control placenta cells plaque reduction neutralization test plasmid toxicity point-of-care diagnostics polymerase chain reaction pregnancy prM-E proteins prostate QCMD replication replicon reporter virus research models and tools reverse genetics rhesus macaques RNA-seq secondary infections serology sexual transmission silvestrol siRNA subgenomic replicon testes testicular cells testis Tet-inducible therapeutics therapy TLR7/8 type I IFN antagonist vaccines validated viral counteraction viral evolution viral fitness viral genetic variation viral pathogenesis viral pathogenicity viral permissiveness viral persistence viral replication viral survival virus attachment virus like particles Zika zika virus Zika virus Zika virus (ZIKV) Ziks virus ZIKV ZIKV-associated neurologic disorders ZIKV-host interactions |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346661103321 |
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Martinez-Sobrido Luis
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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