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Bioinorganic Chemistry of Nickel
| Bioinorganic Chemistry of Nickel |
| Autore | Maroney Michael J |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
InrS
nickel-dependent transcriptional regulators molecular modelling nickel hydrogenase urease Ni-enzymes pathogens ncRNA miRNA lncRNA lung carcinogenesis histidine-rich protein carbon monoxide dehydrogenase nickel chaperone nickel-induced oligomerization urease maturation metallochaperone G-protein conformational change bioavailability carcinogenicity genotoxicity allergy reproductive asthma nanoparticles ecotoxicity environment biological nickel sites nickel-thiolates dinuclear nickel metallopeptides thiolate oxidative damage nickel enzymes reaction mechanism quantum chemical calculations glyoxalase streptomyces mycothiol metalloenzyme AD11 nickel-dependent enzyme methionine salvage pathway methionine S-adenosylmethionine (SAM) methylthioadenosine (MTA) enolase phosphatase 1 (ENOPH1) polyamine matrix metalloproteinase MT1 (MT1-MMP) metalloregulator chaperone [NiFe]-hydrogenase |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557146703321 |
Maroney Michael J
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cholinesterase Research
| Cholinesterase Research |
| Autore | Korabecny Jan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (223 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Amaryllidaceae
Narcissus pseudonarcissus cv. Carlton alkaloids carltonine A-C Alzheimer's disease butyrylcholinesterase docking studies organophosphorus nerve agents oxime cholinesterase reactivation ventilation pharmacodynamics blood-brain barrier crossing acetylcholinesterase inhibitors bone healing osseointegration donepezil hemostasis acetylcholinesterase inhibitor dementia zebrafish behavior Alzheimer disease antioxidants butyrylcholinesterase inhibitors molecular modelling nutraceuticals phytochemicals acetylcholinesterase slow-binding inhibition transition state analog organophosphorus osmotic stress neutron scattering molecular dynamics MD simulations fluorene in vitro in silico multi-target directed ligands N-methyl-d-aspartate receptor molecular modeling reactivators reactivation process organophosphates docking hydrolysis molecular recognition catalysis inhibition |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557764703321 |
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Korabecny Jan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Intrinsically Disordered Proteins and Chronic Diseases
| Intrinsically Disordered Proteins and Chronic Diseases |
| Autore | Kulkarni Prakash |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (224 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
IDP
fuzzy interactions protein complementation assays split-GFP reassembly kinetics membraneless organelles optical tweezer liquid-liquid phase separation protein diffusion depletion interaction entropic force low-complexity sequences intrinsically disordered proteins PAGE4 conformational plasticity order-disorder transition phosphorylation intrinsic disordered protein extremely fuzzy complex protein interaction binding mechanism tumor protein p53 mouse double minute 2 mouse double minute 4 Kinase-inducible domain interacting domain phosphomimetics nuclear magnetic resonance transient secondary structure COR15A Late embryogenesis abundant Trifluoroethanol Nuclear magnetic resonance intrinsically disordered regions functional segments disease-related proteins protein-protein interaction subcellular location glucocorticoid receptor intrinsically disordered transactivation activity gene regulation coactivators microtubule associated protein tau intrinsically disordered protein dynamic configuration free energy landscape microtubules electrostatics diffusion protein structure prediction molecular modelling molecular dynamics tau-microtubule association conformational ensemble replica exchange molecular dynamics drug design |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557746903321 |
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Kulkarni Prakash
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mechanisms of ER Protein Import
| Mechanisms of ER Protein Import |
| Autore | Zimmermann Richard |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
chaperones
contact sites endoplasmic reticulum ER-SURF membrane extraction mitochondria protein targeting bimolecular luminescence complementation competition split luciferase membrane proteins protein-protein interactions Sec61 complex Sec63 synthetic peptide complementation TRAP complex ER protein translocase signal peptide protein translocation nascent peptide chain membrane insertion molecular modelling molecular dynamics simulations molecular docking signal peptidase ER translocon signal recognition particle dependent protein targeting Sec61 dependent translocation co-translational translocation inhibitor high throughput screening Sec61 Sec62 folding insertion membrane protein translocon ribosome transmembrane segment lipid droplets peroxisomes PEX3 membrane protein insertion label-free quantitative mass spectrometry differential protein abundance analysis Zellweger syndrome GET protein transport SND SRP EMC positive-inside rule hydrophobicity transmembrane helix signal recognition particle nascent polypeptide-associated complex fidelity cyclotriazadisulfonamide ER quality control DNAJC3 preprotein Sec61 translocon ribosome stalling signal sequence Sec61 translocase NAC |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576886203321 |
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Zimmermann Richard
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Simulation and Modeling of Nanomaterials
| Simulation and Modeling of Nanomaterials |
| Autore | Bystrov Vladimir S |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (270 p.) |
| Soggetto topico |
Research & information: general
Physics |
| Soggetto non controllato |
single nanowires
silicon dual shells off-resonance absorption photocurrent magnetism transition-metal oxide clusters DFT calculations structure electronic properties LGD theory polarization nanoscale ferroelectrics kinetics homogeneous switching computer simulation fitting diphenylalanine peptide nanotubes self-assembly water molecules DFT molecular modelling semi-empirical methods chirality Ir-modified MoS2 decomposition components of SF6 adsorption and sensing atomistic simulation core–shell bi-magnetic nanoparticles Monte Carlo simulation interfacial exchange terahertz graphene plasmons Drude absorption polarization conversion yield surface plastic flow crystal plasticity polycrystalline aluminum dipeptides helical structures molecular modeling dipole moments tunnel junction machine learning III-nitride hydroxyapatite modeling density functional theory defects vacancies substitutions structural and optical properties band gap electronic density of states nanomaterials plasmon-induced transparency strontium titanate slow light iron doping hydroxyapatite bioceramics hybrid density functional X-ray absorption spectroscopy phenylalanine protein secondary structure optoelectronic devices nanostructured polymer film antireflection coating finite-difference time-domain method ferroelectrics heterostructures domains negative capacitance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585943503321 |
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Bystrov Vladimir S
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications
| Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications |
| Autore | Doti Nunzianna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
polymers
peptidomimetics AFM transfection molecular modelling peptide α-helix hydrocarbon stapling ring-closing metathesis i,i + 1 staple X-ray structure deferoxamine RGD peptides integrins radiodiagnostics PET imaging retro-inverso peptides anticancer peptides drug delivery peptide antigens Aβ IAPP antimicrobial peptides peptides diagnostic ELISA microarray PET SPECT imaging diagnostic non-imaging diagnostic amphiphilic peptides non-viral gene delivery nanocarrier peptide self-assemblies stimuli responsive SARS-CoV-2 FRET molecular docking molecular dynamics MM-GBSA drug repurposing antiviral cancer cyclic peptide integrin αvβ3 ALOS4 melanoma fluorescent peptide environment-sensitive fluorophore peptide labeling luciferin membrane-binding peptide antimicrobial peptide antitumor peptide RGD peptide antiproliferative activity chirality conformational analysis density functional theory (DFT) ferrocene hydrogen bonds peptidomimetic X-ray protein–protein interactions (PPIs) voltage-gated Na+ (Nav) channels fibroblast growth factor 14 (FGF14) medium spiny neurons (MSNs) nucleus accumbens (NAc) neurotherapeutics cyclophilin A (CypA) apoptosis-inducing factor (AIF) human neuroblastoma SH-SY5Y cells staurosporine-mediated cell death AIF(370-394) peptide caspase-3 PARP antifungal antibacterial peptide-based therapies synthetic peptides |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Synthetic Peptides and Peptidomimetics |
| Record Nr. | UNINA-9910580210803321 |
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Doti Nunzianna
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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