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Advances in Plant Alkaloid Research
| Advances in Plant Alkaloid Research |
| Autore | D'Auria John C |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (278 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
canthin-6-one
Picrolemma huberi Simaroubaceae antiplasmodial activity Sarcococca hookeriana sarchookloides A–C steroidal alkaloid cytotoxicity Rhodophiala alkaloids molecular docking AChE BuChE GC-MS Mahonia imbricata Berberidaceae isoquinoline alkaloid mahimbrine A hedgehog signaling Veratrum californicum cyclopamine HPLC-MS Shh-Light II cells halogencyclopropane dichlorocarbene epoxidation vindoline catharanthine dimer alkaloids vindoline trimer Ruta graveolens photosystem II Chl a fluorescence Hill reaction inhibitors acridone alkaloids benzylisoquinoline alkaloids cytochrome P450 monooxygenase medicinal properties methyltransferase Nelumbo nucifera norcoclaurine synthase sacred lotus stereochemistry Aristotelia chilensis Molina Stuntz vascular activity endothelium-independent indole alkaloid 8-oxo-9-dihydromakomakine voltage-dependent calcium channels Catharanthus roseus cambial meristematic cells Aspergillus flavus terpenoid indole alkaloids biosynthesis Buxaceae Borago officinalis Crassocephalum Copper-dependent diamine oxidase Gynura bicolor Homospermidine synthase Lolium perenne Necic acids Necine bases Pyrrolizidine alkaloid biosynthesis Senecionine tropane alkaloids scopolamine cocaine calystegine chemistry pharmacology biotechnological production Erythroxylaceae Erythroxylum coca next generation sequencing traditional medicine bioprospecting tropane late-stage functionalization sulfinate DiversinateTM natural product medicinal chemistry papaverine scaffold library biodiscovery Swinglea glutinosa dereplication acridones phenylacrylamides |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557109903321 |
D'Auria John C
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antioxidant Activity of Polyphenolic Plant Extracts
| Antioxidant Activity of Polyphenolic Plant Extracts |
| Autore | Stagos Dimitrios |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (388 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
green leafy vegetables
effect of cooking polyphenols antioxidant activity Averrhoa bilimbi Oxalidaceae DPPH xanthine oxidase LC-QTOF-MS/MS molecular docking tentative bioactive constituents Dialium indum exocarp seed antioxidant phenolic acids amino acids GC-MS analysis AGN FIR phenolic flavonoid antioxidant capacity antimicrobial activity polyphenol compounds bixin rosemary extracts method validation HPLC food matrices fruit vinegar phenolics organic acid Ladastacho characterisation properties HPLC/ESI-MS HS-SPME/GC-MS beneficial use antimicrobial hydroxytyrosol rosemary pomegranate fish volatile compounds Rosa canina Rosa sempervivens Pyrocantha coccinea antioxidants endothelial cells glutathione almond skins bioavailability waste by-products flavonoids oxidative stress human reactive oxygen species proinflammatory cytokines Alzheimer's disease cornelian cherry anthocyanins gastrointestinal digestion Opuntia ficus-indica cladode antibiofilm activity olive Olea europaea anthocyanin cyanidin 3-glucoside cyanidin 3-rutinoside oxygen radical absorbance capacity (ORAC) high performance liquid chromatography mass spectrometry (HPLC-MS) tea Camellia sinensis polyphenol catechin caffeine theaflavine insulin resistance diabetes olive oil phenols antidiabetic myrtle ultrasound-assisted extraction phenolic compounds liquid chromatography analysis mass spectrometry mulberry (Morus nigra Morus alba) simple sugars organic acids phenol compounds high performance liquid chromatography/diode array detector/mass spectrometry anthocyanins anti-inflammatory activity extraction central composite design optimization P. officinalis phytochemicals cytotoxicity α-amylase inhibition red-osier dogwood antioxidative effect H2O2 transepithelial resistance (TEER) Caco-2 cells Rubus idaeus L. HPLC-ESI-HR-qTOF-MS/MS antioxidant activities digestive enzymes inhibitors molecular docking analysis olive mill wastewater encapsulation maltodextrin whey protein gelatin spray drying diabetes mellitus Lamiaceae alpha-glucosidase alpha-amylase Salvia africana-lutea terpenoids cape floristic region |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557728403321 |
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Stagos Dimitrios
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Molecules from Extreme Environments
| Bioactive Molecules from Extreme Environments |
| Autore | Giordano Daniela |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (244 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Latrunculia
Antarctica deep-sea sponge molecular networking molecular docking discorhabdin Arctic/Antarctic environment biocatalysis cold-adaptation marine biotechnology deep sea extremophilic microorganisms extremozyme thermophilic enzyme psychrophilic enzyme halophilic enzyme piezophilic enzyme chitinase cold-adapted optimization antifungal Pseudomonas Deinococcus deinoxanthin carotenoid deep-sea extreme ecosystem fungi bioactive compounds secondary metabolites halophilic bacteria archaea and fungi biomolecules biomedicine antimicrobial compounds anticancer compounds green synthesis biomaterials silver nitrate antibiotics nanotechnology marine prokaryotes microbial diversity polyextremophiles deep hypersaline anoxic basins blue biotechnologies extremozymes limits of life Antarctic krill (Euphausia superba) genome survey mitochondrial genome whiteleg shrimp (Penaeus vannamei) antimicrobial peptide (AMP) antihypertensive peptide (AHTP) cypermethrin biosurfactants biodegradation capacities marine sediments Arctic/Antarctic deep hypersaline anoxic basin cold-adapted bacteria halophilic microorganisms marine natural product enzyme silver nanoparticle marine bioprospecting |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557147603321 |
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Giordano Daniela
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactives and Functional Ingredients in Foods
| Bioactives and Functional Ingredients in Foods |
| Autore | Pacifico Severina |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (290 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
antioxidant effect
lectins nanoliposomes purity grade quercetin trans-aconitic acid anthocyanins antioxidant activity bioactive compounds colorants fruit juices polyphenols wild blueberry antidiabetic cardioprotective functional foods nutraceuticals okra phytotherapy Jamaican cherry fermentation Lactobacillus plantarum antioxidant food nutrition improvement okra mucilage okra polysaccharides biopolymer α-amylase activity α-glucosidase activity antidiabetic activity biodegradable edible film release pectin sodium caseinate oil oxidation waste biomass coffee Coffea arabica phenolic free-radical scavenging iron chelating cytotoxic plant secondary metabolites antiviral activity food noroviruses MNV FCV yogurt betalains encapsulation lyophilization ionizing radiation radioprotection flavonoids plant extracts oxidative stress zebrafish embryo carotenoids Trapa bispinosa Roxb polyphenol ellagitannin gallotannin α-glucosidase inhibitor advanced glycation end products (AGEs) antiglycation effect LC/UV/ESIMS analysis anti-diabetic abscisic acid Diabetes mellitus molecular docking phytohormones spray drying vegetable powders beetroot natural colorants violet betalain pigments bioactivity medicinal plants wild fruits industrial crops PCA HCA phenols TEAC roasting GAE |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595072703321 |
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Pacifico Severina
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioinformatics and Machine Learning for Cancer Biology
| Bioinformatics and Machine Learning for Cancer Biology |
| Autore | Wan Shibiao |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
tumor mutational burden
DNA damage repair genes immunotherapy biomarker biomedical informatics breast cancer estrogen receptor alpha persistent organic pollutants drug-drug interaction networks molecular docking NGS ctDNA VAF liquid biopsy filtering variant calling DEGs diagnosis ovarian cancer PUS7 RMGs CPA4 bladder urothelial carcinoma immune cells T cell exhaustion checkpoint architectural distortion image processing depth-wise convolutional neural network mammography bladder cancer Annexin family survival analysis prognostic signature therapeutic target R Shiny application RNA-seq proteomics multi-omics analysis T-cell acute lymphoblastic leukemia CCLE sitagliptin thyroid cancer (THCA) papillary thyroid cancer (PTCa) thyroidectomy metastasis drug resistance biomarker identification transcriptomics machine learning prediction variable selection major histocompatibility complex bidirectional long short-term memory neural network deep learning cancer incidence mortality modeling forecasting Google Trends Romania ARIMA TBATS NNAR |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595077403321 |
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Wan Shibiao
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological Potential and Medical Use of Secondary Metabolites
| Biological Potential and Medical Use of Secondary Metabolites |
| Autore | Seca Ana M. L |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (284 p.) |
| Soggetto non controllato |
antitumor
triterpenoids seaweeds diterpenes Boswellia antioxidant activity antiplasmodial Maytenus chiapensis phenolic derivatives secondary metabolites medicinal applications Malus x domestica pectin cytotoxic activity xanthine oxidase phytochemistry antioxidant Scabiosa sugars sargaquinoic acid pentacyclic triterpenoids analysis antimicrobial and anticancer activity iridoids Tuscany GC-MS (-)-rabdosiin kratom plant defense cembranoids tingenone deoxypodophyllotoxin anticancer pristimerin inflammation boswellic acids plants anti-inflammatory legalization Mitragyna speciosa Ocimum sanctum cordycepin cytotoxic medicine Artemisia species antimicrobial activity lignans Artemisia vachanica Cordyceps militaris frankincense ancient varieties sargahydroquinoic acid Tajikistan antiSMASH ABTS polyphenols therapeutics infectious diseases antibacterial nutraceutics total phenolics LC-MS/MS innate immunity HPLC-PAD sarganaphthoquinoic acid biosynthetic gene clusters DPPH EGCG cneorubenoids PPAR-? bowel diseases amentoflavone molecular docking sargachromenoic acid cannabinoids flavonoids essential oils TCM HPLC-PDA ascorbic acid antioxidants Lamiaceae nanoemulsion malaria therapeutic uses quinonemethide triterpenoids artemisinin natural products biological activities FRAP toxicology defensins Celastraceae cannabis vector control Juniperus analytical determination |
| ISBN | 3-03921-188-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346847303321 |
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Seca Ana M. L
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemoinformatics Approaches to Structure- and Ligand-Based Drug Design
| Chemoinformatics Approaches to Structure- and Ligand-Based Drug Design |
| Autore | Andricopulo Adriano D |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (415 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico |
Science: general issues
Pharmacology |
| Soggetto non controllato |
chemoinformatics
drug design Molecular modeling Computational Chemistry QSAR molecular docking QSPR Virtual Screening molecular dynamics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557666603321 |
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Andricopulo Adriano D
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics
| Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics |
| Autore | Tutone Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (387 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
3D-QSAR
pharmacophore modeling ligand-based model HDACs isoform-selective histone deacetylase inhibitors aminophenylbenzamide hERG toxicity drug discovery fingerprints machine learning deep learning gene expression signature drug repositioning approaches RNA expression regulation high-throughput virtual screening dual-target lead discovery neurodegenerative disorders Alzheimer's disease dual mode of action multi-modal nicotinic acetylcholine receptor acetylcholinesterase molecular docking methotrexate drug resistance human dihydrofolate reductase virtual screening molecular dynamics simulation epitope binning epitope mapping epitope prediction antibody:antigen interactions protein docking glycoprotein D (gD) herpes simplex virus fusion proteins Src inhibitors pharmacophore model molecular dynamics simulations in silico COX-2 inhibitors molecular modeling sodium-glucose co-transporters 2 FimH uropathogenic bacteria urinary tract infections diabetes drug-resistance mutations HIV-2 protease structural characterization induced structural deformations SARS-CoV-2 COVID-19 multiprotein inhibiting natural compounds MD simulation 3CL-Pro antivirals docking simulations drug repurposing consensus models binding space isomeric space MRP4 SNPs variants protein threading modeling molecular dynamics binding site hTSPO PK11195 cholesterol homology modeling molecular dynamics (MD) simulation carbon nanotubes Stone-Wales defects haeckelite defects doxorubicin encapsulation drug delivery system binding free energies noncovalent interactions main protease mutants inhibitors PF-00835231 Mycobacterium tuberculosis tuberculosis proteasome natural compounds multiscale multitargeting polypharmacology computational biology drug repositioning structural bioinformatics proteomic signature skin aging oxidative stress aging progression mechanism genome-wide genetic and epigenetic network (GWGEN) systems medicine design multiple-molecule drug immunoproteasome non-covalent inhibitors MD binding metadynamics induced-fit docking |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Computational Approaches |
| Record Nr. | UNINA-9910557519403321 |
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Tutone Marco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dedicated to the 55th Anniversary of G.B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences
| Dedicated to the 55th Anniversary of G.B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences |
| Autore | Dmitrenok Pavel S |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
polyhydroxylated steroids
NMR spectra starfish Anthenoides laevigatus cytotoxicity soft agar assay kainic acid domoic acid dysiherbaine neodysiherbaine A marine bacteria whole genome sequence porin amino acids composition bilayer lipid membrane pore-forming activity spatial structure phlorotannins phlorethols anticancer activity colorectal cancer radiosensitizer radiotherapy 1,4-naphthoquinones quinoid compounds thioglycosides quinone-sugar conjugates cytotoxic activity antibiotic activity histochrome echinochrome A oxidative degradation HPLC-DAD-MS NMR actinoporin sea anemone Heteractis crispa anti-migratory activity glycosphingolipids cerebrosides peroxidation products structure elucidation allylic thioether ESI-MS GC-MS mass spectra glass sponge isomalabaricanes Stelletta sp marine sponge terpenoid Cobetia amphilecti Cobetia litoralis Cobetia pacifica Cobetia marina Cobetia crustatorum identification markers alkaline phosphatase PhoA lanosterol 14-alpha demethylase flavonoids enzyme inhibition surface plasmon resonance spectral titration molecular docking Zobellia genomes polysaccharide lyase family 7 alginate utilization system paralogs orthologs recombinant phospholipase A1 Yersinia pseudotuberculosis inclusion bodies fusion protein green fluorescent protein porin gene expression antibiotic stress phenotypic heterogeneity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557717403321 |
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Dmitrenok Pavel S
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Repositioning: Current Advances and Future Perspectives
| Drug Repositioning: Current Advances and Future Perspectives |
| Autore | Yuhei Nishimura |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (153 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
database
Integrative strategies molecular docking polypharmacology multi-omics computational analysis Drug Repositioning data sharing Patenting |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Drug Repositioning |
| Record Nr. | UNINA-9910346734903321 |
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Yuhei Nishimura
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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