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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (418 p.) |
| Soggetto non controllato |
cancer treatment
extreme learning independent prognostic power AID/APOBEC HP gene inactivation biomarkers biomarker discovery chemotherapy artificial intelligence epigenetics comorbidity score denoising autoencoders protein single-biomarkers gene signature extraction high-throughput analysis concatenated deep feature feature selection differential gene expression analysis colorectal cancer ovarian cancer multiple-biomarkers gefitinib cancer biomarkers classification cancer biomarker mutation hierarchical clustering analysis HNSCC cell-free DNA network analysis drug resistance hTERT variable selection KRAS mutation single-cell sequencing network target skin cutaneous melanoma telomeres Neoantigen Prediction datasets clinical/environmental factors StAR PD-L1 miRNA circulating tumor DNA (ctDNA) false discovery rate predictive model Computational Immunology brain metastases observed survival interval next generation sequencing brain machine learning cancer prognosis copy number aberration mutable motif steroidogenic enzymes tumor mortality tumor microenvironment somatic mutation transcriptional signatures omics profiles mitochondrial metabolism Bufadienolide-like chemicals cancer-related pathways intratumor heterogeneity estrogen locoregionally advanced RNA feature extraction and interpretation treatment de-escalation activation induced deaminase knockoffs R package copy number variation gene loss biomarkers cancer CRISPR overall survival histopathological imaging self-organizing map Network Analysis oral cancer biostatistics firehose Bioinformatics tool alternative splicing biomarkers diseases genes histopathological imaging features imaging TCGA decision support systems The Cancer Genome Atlas molecular subtypes molecular mechanism omics curative surgery network pharmacology methylation bioinformatics neurological disorders precision medicine cancer modeling miRNAs breast cancer detection functional analysis biomarker signature anti-cancer hormone sensitive cancers deep learning DNA sequence profile pancreatic cancer telomerase Monte Carlo mixture of normal distributions survival analysis tumor infiltrating lymphocytes curation pathophysiology GEO DataSets head and neck cancer gene expression analysis erlotinib meta-analysis traditional Chinese medicine breast cancer TCGA mining breast cancer prognosis microarray DNA interaction health strengthening herb cancer genomic instability |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Energy Metabolism and Diet
| Energy Metabolism and Diet |
| Autore | Nieuwenhuizen Arie |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (114 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
insulin
lipogenesis obesity glucose homeostasis adipocytes cortisol ketones s-IgA exercise low carbohydrate diet NAFLD omega-3 krill oil phospholipids high-fat diet C57BL/6N mice thermoneutral temperature iron deficiency striated skeletal muscle physical capacity fatigue mitochondrial metabolism complex I resting metabolic rate prediction equation ageing adults overweight adiposity-based chronic disease energy balance metabolism |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576883203321 |
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Nieuwenhuizen Arie
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondria : the cell powerhouse and nexus of stress / / topic editors: Sabzali Javadov and Andrey V. Kuznetsov
| Mitochondria : the cell powerhouse and nexus of stress / / topic editors: Sabzali Javadov and Andrey V. Kuznetsov |
| Autore | Andrey V. Kuznetsov |
| Pubbl/distr/stampa | Frontiers Media SA, 2014 |
| Descrizione fisica | 1 online resource (121 pages) : illustrations; digital, PDF file(s) |
| Collana | Frontiers Research Topics |
| Soggetto topico |
Cytology
Biology Health & Biological Sciences |
| Soggetto non controllato |
mitochondrial physiology
Oxidative Stress Cell Death Mitochondrial ion channels mitochondrial metabolism |
| ISBN | 9782889192830 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137196803321 |
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Andrey V. Kuznetsov
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| Frontiers Media SA, 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondrial Transport Proteins
| Mitochondrial Transport Proteins |
| Autore | Palmieri Ferdinando |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (476 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
hypoxia
resistance to hypoxia mitochondria mitochondrial calcium transport mitochondrial calcium uniporter complex mitochondrial Ca2+-induced permeability transition pore cyclophilin D ATP synthase disease error of metabolism mitochondrial carrier mitochondrial carrier disease mitochondrial disease mitochondrial transporter membrane transport mutation SLC25 mitochondrial permeability transition apoptosis necrosis ischemia/reperfusion cancer neurodegeneration cyclosporin A metabolite transport mitochondrial pyruvate carrier sideroflexin TOM TIM chaperones TIM22 protein translocation mitochondrial biogenesis amino acid biological function ion inner mitochondrial membrane mitochondrial carrier family organic acid substrate specificity transport mechanism vitamin USMG5/DAPIT glucose-stimulated insulin secretion glucose-induced expression membrane subunits of ATP synthase ATP synthase oligomers mitochondrial cristae morphology metabolism metabolic disorders adult-onset type II citrullinemia (CTLN2) aspartate/glutamate carrier (AGC) animal model argininosuccinate synthetase (ASS) aversion to carbohydrates citrin food taste neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) protein–protein interaction MPC lifespan pyruvate metabolism mitochondrial transport peroxisomes carrier cofactor ABC transporter aquaporin ion channels potassium channels ATP calcium ROS potassium channel openers MCF function plant metabolism plant development diseases VDAC1 virus pancreatic islets β-cell diabetes glucotoxicity glucolipotoxicity lipotoxicity mitochondrial carriers SLC transporters SLC54 SLC55 LETM SLC56 sequence analysis protein targeting Voltage-Dependent Anion selective Channel isoforms oxidative post-translational modification gene promoter yeast bioenergetics SLC25A1 CIC CTP citrate inflammation 22.q11.2 NAFLD/NASH carnitine carnitine acyl-carnitine carrier carnitine acyl-carnitine translocase post-translational modification solute carrier family 25 SLC25A20 MCU mitochondrial Ca2+ uniporter Ca2+ signaling mitochondrial metabolism skeletal muscle mitochondria SLC25A51 NAD+ transporters NAD electrophysiology ATP-dependent potassium channel |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566465303321 |
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Palmieri Ferdinando
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Redox Imbalance and Mitochondrial Abnormalities in Kidney Disease
| Redox Imbalance and Mitochondrial Abnormalities in Kidney Disease |
| Autore | Yan Liang-Jun |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (200 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
diabetic kidney disease
caloric restriction NADH/NAD+ redox imbalance mitochondrial homeostasis mitophagy oxidative stress kidney allograft kidney rejection ischemia acute kidney injury (AKI) chronic kidney disease (CKD) tricarboxylic acid (TCA) cycle mitochondrial metabolism mitochondrial redox signaling mitochondrial proteins oxidative phosphorylation (OXPHOS) fatty acid (FA) β-oxidation mitochondrial dynamics biogenesis diabetes kidney mitochondria Oryza sativa rice husk TCA cycle metabolites kidney diseases renalase chronic kidney disease major adverse cardiovascular outcomes cadmium kidney injury renal toxicity oxidative damage proximal tubule controlled oxygenated rewarming mitochondrial uncoupling rewarming injury temperature paradox redox mitochondrial dysfunction SGLT2 mitochondrial reactive oxygen species Warburg effect podocytopathies mitochondrial oxidative stress reactive oxygen species (ROS) antioxidant defense cell death |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566465703321 |
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Yan Liang-Jun
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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