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Characterization and Clinical Management of Dilated Cardiomyopathy
| Characterization and Clinical Management of Dilated Cardiomyopathy |
| Autore | Merlo Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (232 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
alternative splicing
arrhythmias arrhythmic risk stratification atrial fibrillation biomarkers calcium cardiac channelopathy cardiac magnetic resonance cardiac magnetic resonance imaging cardiac resynchronization therapy cardiac sodium channel cardiomyopathy congenital heart disease congestive heart failure desmin diastolic dysfunction dilated cardiomyopathy DNA methylation duchenne muscular distrophy epigenetics gene therapy genetics heart heart failure laminopathy late gadolinium enhancement left atrial strain left ventricle non-compaction cardiomyopathy left ventricle sphericity index left ventricular noncompaction left ventricular reverse remodelling LMNA long axis strain long-term outcomes major adverse cardiovascular events malignant ventricular arrhythmia mammalian target of rapamycin (mTOR) complex-1 mdx membrane stabilization mitochondrial dysfunction muscular dystrophy myopathy n/a non-ischemic cardiomyopathy non-sense mRNA decay nonischemic dilated cardiomyopathy NT-proBNP oxidative stress phospholamban phosphorylation precision medicine RNA binding motif protein 20 (RBM20) sarcomere SCN5A Serca2a sex differences supraventricular arrhythmia systolic dysfunction tachycardiomyopathy titin troponin T ventricular arrhythmia whole exome sequencing |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557595503321 |
Merlo Marco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology
| Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology |
| Autore | Fioravanti Antonella |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (320 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
acute myocardial infarction
ALS Alzheimer's disease antioxidants antisense oligonucleotide apoptosis ASH autophagy beta cells breast cancer cancer chemoresistance clinical trial cross-talk diabetes endometriosis endometriosis-associated ovarian cancer epithelial-to-mesenchymal transition HBV HCC HCV high-grade serous ovarian cancer Huntington's disease hypoxia liver cancer long noncoding RNA metabolism microRNA MicroRNA MicroRNA (miRNA) microRNAs miR-27a-5p miR526b miR655 miRNA miRNAs mitochondrial dysfunction n/a NAFLD NASH neurodegeneration NF-κB nitrosative stress. exosome noncoding RNA nucleic acid medicine osteoarthritis oxidative stress pancreatic cancer Parkinson's disease physiology reactive oxygen species reactive oxygen species (ROS) redox signaling resistin ROS signal transduction siRNA superoxide (SO) synovial fibroblasts synovitis systemic lupus erythematosus therapeutic resistance therapeutic target therapeutic tolerance Thioredoxin Reductase 1 (TXNRD1) thyroid hormone translation regulation visfatin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557526003321 |
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Fioravanti Antonella
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dietary Intakes and Metabolic Disorders
| Dietary Intakes and Metabolic Disorders |
| Autore | Chiva-Blanch Gemma |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
animal experimentation
diet nutrition ingredients lard fibers fructose diet coloring autoclaving irradiation Passiflora setacea bioactive compounds phenolic compounds cardiovascular diseases nutrigenomics gene expression immune system cytokines insulin HDL diabetes mellitus dietary pattern metabotype metabolic phenotype Mediterranean Diet Score Alternate Healthy Eating Index atherosclerosis plaque burden lycopene tomato type 2 diabetes mellitus cis- and trans-isomers nutrients hypertension blood pressure management prevention mitochondria metabolic syndrome mitochondrial dysfunction balanced diet lifestyle Mediterranean diet plant-based diet DASH diet low-carbohydrate diet high-protein diet low-fat diet omega-3 fatty acids metabolism inflammation atherothrombosis clinical trials legacy effect metabolic memory cardiovascular disease diabetes dyslipidaemia abdominal obesity animal protein protein intake Alpha-linolenic acid docosahexaenoic acid rumenic acid punicic acid enriched eggs waist circumference obesity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069903321 |
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Chiva-Blanch Gemma
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Hallmarks of Parkinson’s Disease
| Hallmarks of Parkinson’s Disease |
| Autore | Alves Da Costa Cristine |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (124 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
Parkinson’s disease
unfolded protein response reticulum endoplasmic genetics alpha-synuclein prion-like spreading cell-to-cell transfer neurodegeneration mitochondrial dysfunction PINK1 neurons astrocytes microglia α-synuclein exocytosis lipids membranes Parkinson disease SNARE complex synapse vesicle fusion therapeutic target protein quality control mitochondrial quality control ubiquitin alpha-syn mitophagy Parkin mito-Keima mito-QC mito-SRAI |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069503321 |
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Alves Da Costa Cristine
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Impaired Mitochondrial Bioenergetics under Pathological Conditions
| Impaired Mitochondrial Bioenergetics under Pathological Conditions |
| Autore | Lenaz Giorgio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (460 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research & information: general |
| Soggetto non controllato |
aging
aging heart assembly factor ATP synthase ATP synthase/hydrolase atypical myopathy Barth syndrome Bcl-2 family bioenergetics C cancer cardiolipin cardiomyopathy cell culture cell signaling cellular bioenergetics cellular signaling complex I assembly complex I deficiency complex I structure complex III COVID-19 cristae cytochrome b diabetes Dilated Cardiomyopathy with Ataxia electron transport chain energy metabolism entorhinal cortex equine primary myoblasts exercise fatty acid oxidation fibroblasts frozen tissue G mutation glucagon heart failure high-resolution respirometry human disease immune system influenza innate immune response insulin Leigh syndrome leukocytes lipoxidation-derived damage m.3243A> m.8909T> mammalian complex I mathematical model MAVS MDA5 metabolic disease mitochondria mitochondrial disease mitochondrial diseases mitochondrial DNA mitochondrial dynamic mitochondrial dynamics mitochondrial dysfunction mitochondrial permeability transition pore mitochondrial proteostasis MT-ATP6 MTCYB mutations n/a NADH dehydrogenase nephropathy neurodegeneration oleate oxidative damage oxidative phosphorylation oxidative stress oxygen consumption palmitate pancreatic endocrine cells pet mutants platelets programmed cell death protein import respiratory chain respiratory complex assembly respiratory complexes respiratory supercomplexes respirometry RIG-I ROS RSV Saccharomyces cerevisiae SARS CoV-2 Sengers syndrome skeletal muscle supercomplexes supernumerary subunits toxicity assays viral infections yeast |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585934503321 |
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Lenaz Giorgio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (480 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
12-deacetyl-12-epi-scalaradial
3-alkylpyridinium polymers A375 and HeLa cell lines A549 cells ABC transporter actinomycin AD0157 adriamycin resistance Aeroplysinin Akt angiogenesis angiogenesis inhibitor ansamycins anthranilic acid anti-angiogenesis anti-angiogenic anti-cancer anti-metastatic activity anti-proliferation anti-proliferative antiangiogenesis antiangiogenic antibacterial Antibody Drug Conjugates (ADCs) anticancer anticancer activity anticancer agent anticancer immunity anticarcinogenic anticoagulant anticoagulation antifouling Antimicrobial peptide (AMP) antioxidant antiproliferative antiproliferative activity antitumor antitumor activities antitumoral antitumour AP-1 apoptosis apoptosis-inducing activity approved antitumor agents araguspongine C arrest of cell cycle Aspergillus autophagy autophagy inducers autophagy inhibitors azoxymethane BCRP/ABCG2 BEL-7402 cell benzo[a]pyrene bioactive natural product bioanalysis bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) bonnethead shark breast cancer breast cancer cells Brevianamide brominated indoles bromophenol buccal gland c-JUN c-Met C15 acetogenins camptothecin cancer Cancer cancer genes cancer preventive cancer progression Cantabrian Sea-derived actinobacteria carbocyclic analogue carcinoembryonic antigen Caribbean sponge carotenoid carotenoids caspase cascade cell adhesion cell adhesion molecules cell cycle cell cycle arrest cell migration cembranoids chemical conjugation chemoprevention chemopreventive chemosensitization chemotherapy chimera CHOP chromatography circulating tumor cells cisplatin clinical trials colorectal cancer cooperative binding cyclin D1 cyclin-dependent kinase CYP1A1 cystatin F cystatin superfamily cytokine release cytoskeleton cytotoxic activity cytotoxicity deep-sea depolymerisation dibromotyrosine dieckol divergolides DNA minor groove binder drug discovery Ecklonia cava elisidepsin EMT endoperoxide endophytic fungus endothelial cells energy stress epigonal organ epithelial-mesenchymal transition ER-stress ET-743 evolution FAK fascaplysin fatty acid 2-hydroxylase fatty acids FAU FBDD fucoidan fucoxanthin fumigaclavine C gemcitabine gene expression glioblastoma gliotoxin glucocorticoid receptor glycosaminoglycans gorgonian Haliclona gracilis HeLa cells heparan sulphate heparanase hepatocellular carcinoma HER2 HIF-1 hippuristanol HSP90 human lung cancer human normal diploid fibroblast (TIG-1 cells) human sarcoma cell line (HT1080 cells) humulane sesquiterpenoids hybridization hydroxylated lipids hypoxia hypoxia-inducible factor-1 IL-6 in vivo model inflammation inhibitor integrin β1 invasion isatin Isofistularin itampolin A jaspine B JNK1/2 Jurkat kalkitoxin kunitz type inhibitor Lampetra morii Leathesia nana Leptogorgia leukemia lipid rafts low molecular weight fucoidan extract low toxic LS-1 lung cancer lung metastasis Lyngbya majuscula macrolide mangrove-derived actinomycete manzamine A MAPK/ERK pathway marangucyclines marine antitumor agents marine biotechnology marine compound marine drug marine drugs marine fungus marine metabolites marine mollusc marine natural products marine organisms marine sponges marine-derived drugs Marthasterias glacialis L. MCP-1 mechanisms of action melanoma membrane permeabilization metastasis microalgae Micromonospora migration mitochondria mitochondria toxin mitochondrial pathway mitochondrial dysfunction molecular docking molecular mechanisms molecular modeling molecular oncology Moorea producens MRP1/ABCC1 multi-drug resistant leukemia multidrug resistance Mycalin A Mycochromenic acid derivative N-Ras n/a nanoparticle naphthopyrones natural marine compounds natural product natural products neuroblastoma-rat sarcoma NF-κB NF-κB signaling nicotine nicotinic acetylcholine receptor non-small cell lung cancer non-small cell lung cancer (NSCLC) non-small cell lung carcinoma nonfunctioning pituitary adenomas novel inhibitor NSCLC Nur77 osteosarcoma oxidative stress oxidative stress P-gp/ABCB1 P2X7 receptor p38 p38/ERK p38α p65 pachastrissamine palmitic acid paulomycins pazopanib PEL Penicillium brevicompactum Penicillium paneum phase I pheochromocytoma and paraganglioma phlorotannins phycocyanin PI3K/Akt plakortide plitidepsin pollution poly(ADP-ribose)-polymerase inhibitor polyoxygenated steroids polyphenols polysaccharides Porifera porifera/sponge preclinical programmed cell death programmed cell death-ligand 1 programmed cell death-ligand 2 proliferation prostate cancer proteasomal degradation proteomic pseudopterosin puupehenones pyrrolidinedione reactive oxygen species RGD motif ribosomal protein genes ROS RPS30 safety Sarcophyton ehrenbergi sea anemone sea cucumbers seaweed secondary metabolites sediment selenium-containing polysaccharide-protein complex Sepia ink polysaccharides shrimp signal transduction sinulariolide sipholenol A small cell lung cancer SNORA62 snoRNA SNU-C5/5-FU soft coral soft tissue sarcoma soft tissue sarcoma sphingosine kinase inhibitor sponge sponges STAT3 Streptomyces sp. SCSIO 11594 synergism synthetic analogues SZ-685C targeted therapy terpenes tetracenomycin X TGF-β signaling Thalassia testudinum thalassiolin B therapeutic compounds Tilapia piscidin 4 (TP4) TNFα Topo I inhibitor topoisomerase trabectedin triterpene glycosides TRPM7 tumor cell line tumor microenvironment tumor-associated macrophages Ulva fasciata uveal melanoma VEGF virtual screening xyloketal B α9-nicotinic acetylcholine receptors (nAChRs) αO-conotoxin GeXIVA β1-integrin λ-carrageenan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metabolomics in Neurodegenerative Disease
| Metabolomics in Neurodegenerative Disease |
| Autore | Green Brian |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (184 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
?-synuclein aggregates
13C-labeled succinate 1H NMR 6-OHDA age-related macular degeneration Alzheimer's disease bile acids biomarkers C. elegans cerebral ischemia cerebral palsy dementia with Lewy bodies direct mass spectrometry drusen endothelin-1 energy metabolism excitotoxicity fatty acid fatty acid metabolism GC-MS glutamic acid imaging mass spectrometry LC-MS lipidomics malonate mass spectrometry metabolic pathways metabolism metabolomics micro-dialysis midbrain mitochondrial dysfunction myo-inositol n/a natural product neurodegeneration Parkinson's disease Parkinson's disease dementia pathogenesis plasma prodromal Parkinson's disease reperfusion retinal pigment epithelium Streptomyces venezuelae subacute mild traumatic brain injury targeted mass spectrometry tricarboxylic acid cycle |
| ISBN | 3-03928-041-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087203321 |
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Green Brian
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondria in Health and Diseases
| Mitochondria in Health and Diseases |
| Autore | Javadov Sabzali |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (434 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
2-oxoglutarate dehydrogenase
4-HNE adenine nucleotide translocase ADP/ATP carrier aging amino acid neurotransmitter ancient mutation antioxidant system antioxidants apoptosis BAX BCL-2 BKCa channels cardiolipin cardiomyocytes cardioprotection cerebellar amino acid metabolism cholangiocellular carcinoma colon complex I (CI) deficiency cyclosporin A cytoskeletal proteins DDE dentate granule cell development dextran DRP1 dsRNA electron and confocal microscopy electron tunneling (ET) energy metabolism epilepsy ERK1/2 ETC complexes fatty acid oxidation ferritin gemfibrozil GW9662 H9c2 cardiomyoblasts healthy cells heart hepatic fibrogenesis hepcidin high-fat diet hippocampus HtrA2/Omi human amniotic membrane human diseases hyperforin hypoglycemia hypoxia inflammation innate immunity inorganic phosphate interferon response intranuclear mitochondria ion homeostasis iron overload ischemia reperfusion injury JNK KmADP Langendorff LHON life span lipid droplet lipid handling liver LONP1 metabolome and proteome profiling mitochondria mitochondria bioenergetics mitochondria calcium buffering mitochondria permeability transition pore mitochondria: energy metabolism mitochondrial cell death mitochondrial connexin 43 mitochondrial dynamics mitochondrial dysfunction mitochondrial function mitochondrial gene expression mitochondrial homeostasis mitochondrial interactions mitochondrial permeability transition pores mitochondrial UCP2 morphology mtDNA mtDNA transcription mtRNA muscle aging myocardial neuron death neuroprotection oxidative phosphorylation oxidative stress perilipin 5 physical performance pilocarpine pioglitazone PKA plectin post-transcriptional mtRNA processing potassium channel pravastatin protein phosphatases pyruvate dehydrogenase pyruvate dehydrogenase kinase reactive oxygen species reactive oxygen species (ROS) reactive oxygen species stress redox state regeneration respirasome assembly respiratory supercomplexes ROS rosiglitazone seizure Siberian population signaling signaling pathways siRNA sodium dichloroacetate specific genetic background telomerase activity telomere length tensile strength transferrin tricarboxylic acid cycle tubulin beta TUNEL TZD uncoupling uncoupling protein ZIP |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557577203321 |
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Javadov Sabzali
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondrial Dysfunction and Neurodegeneration
| Mitochondrial Dysfunction and Neurodegeneration |
| Autore | Tapias Victor |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (209 p.) |
| Soggetto topico |
Neurosciences
Science: general issues |
| Soggetto non controllato |
Alzheimer's disease
mitochondrial dysfunction neurodegenerative diseases Parkinson's disease quality control |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557387303321 |
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Tapias Victor
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondrial Dysfunction in Aging and Diseases of Aging / Richard H. Haas
| Mitochondrial Dysfunction in Aging and Diseases of Aging / Richard H. Haas |
| Autore | Haas Richard H |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (270 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
age-related diseases
sphingolipids glaucoma ALS neurodegeneration mitochondrial dysfunction adaptive immunity senescence de-emergence innate immunity cell danger response mitochondrial transfer axonal transport cytokines mitochondrial age-related macular degeneration prevention heart failure purinergic signaling autophagy Alzheimer's disease diabetic retinopathy proteostasis 1 immunosenescence Miro1 ROS metabolism optic nerve polypharmacy eIF2? Parkin coenzyme Q10 neurodegenerative disease DNA damage skin exercise nucleotide metabolism pasteur effect stress response inflammation retina drug-induced mitochondrial toxicity neuroinflammation exosomes reactive oxygen species 25(OH)D cardiomyopathy crabtree effect insulin resistance cardiovascular disease ageing genetic mutations metabokines mitochondria multiple sclerosis aerobic healing cycle SOD1 mitophagy PINK1 type 2 diabetes integrated cell stress response morbidity and mortality ultraviolet photoageing cancer aging 25(OH)2D lysosome NAD+ Parkinson's disease |
| ISBN |
9783039213283
3039213288 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756303321 |
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Haas Richard H
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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