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Characterization and Clinical Management of Dilated Cardiomyopathy
| Characterization and Clinical Management of Dilated Cardiomyopathy |
| Autore | Merlo Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (232 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
SCN5A
cardiac sodium channel cardiac channelopathy dilated cardiomyopathy precision medicine arrhythmias atrial fibrillation cardiomyopathy heart failure supraventricular arrhythmia systolic dysfunction tachycardiomyopathy ventricular arrhythmia left atrial strain cardiac resynchronization therapy muscular dystrophy calcium heart gene therapy phospholamban Serca2a mdx oxidative stress membrane stabilization left ventricular noncompaction congenital heart disease congestive heart failure non-ischemic cardiomyopathy genetics desmin mitochondrial dysfunction myopathy whole exome sequencing laminopathy LMNA biomarkers troponin T NT-proBNP malignant ventricular arrhythmia arrhythmic risk stratification DNA methylation alternative splicing epigenetics nonischemic dilated cardiomyopathy cardiac magnetic resonance imaging late gadolinium enhancement long axis strain left ventricle sphericity index major adverse cardiovascular events sex differences left ventricular reverse remodelling long-term outcomes left ventricle non-compaction cardiomyopathy cardiac magnetic resonance titin RNA binding motif protein 20 (RBM20) sarcomere diastolic dysfunction phosphorylation non-sense mRNA decay mammalian target of rapamycin (mTOR) complex-1 duchenne muscular distrophy |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557595503321 |
Merlo Marco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology
| Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology |
| Autore | Fioravanti Antonella |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (320 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
miR-27a-5p
acute myocardial infarction autophagy apoptosis hypoxia MicroRNA (miRNA) miR526b miR655 oxidative stress reactive oxygen species (ROS) superoxide (SO) Thioredoxin Reductase 1 (TXNRD1) breast cancer nucleic acid medicine pancreatic cancer clinical trial siRNA antisense oligonucleotide MicroRNA signal transduction therapeutic target miRNAs ROS noncoding RNA microRNA long noncoding RNA mitochondrial dysfunction nitrosative stress. exosome cross-talk systemic lupus erythematosus visfatin resistin osteoarthritis synovial fibroblasts synovitis NF-κB thyroid hormone liver cancer metabolism physiology ASH NAFLD NASH HCC HCV HBV endometriosis high-grade serous ovarian cancer endometriosis-associated ovarian cancer epithelial-to-mesenchymal transition chemoresistance antioxidants miRNA cancer diabetes beta cells microRNAs translation regulation neurodegeneration Alzheimer's disease Parkinson's disease Huntington's disease ALS reactive oxygen species redox signaling therapeutic tolerance therapeutic resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557526003321 |
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Fioravanti Antonella
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dietary Intakes and Metabolic Disorders
| Dietary Intakes and Metabolic Disorders |
| Autore | Chiva-Blanch Gemma |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
animal experimentation
diet nutrition ingredients lard fibers fructose diet coloring autoclaving irradiation Passiflora setacea bioactive compounds phenolic compounds cardiovascular diseases nutrigenomics gene expression immune system cytokines insulin HDL diabetes mellitus dietary pattern metabotype metabolic phenotype Mediterranean Diet Score Alternate Healthy Eating Index atherosclerosis plaque burden lycopene tomato type 2 diabetes mellitus cis- and trans-isomers nutrients hypertension blood pressure management prevention mitochondria metabolic syndrome mitochondrial dysfunction balanced diet lifestyle Mediterranean diet plant-based diet DASH diet low-carbohydrate diet high-protein diet low-fat diet omega-3 fatty acids metabolism inflammation atherothrombosis clinical trials legacy effect metabolic memory cardiovascular disease diabetes dyslipidaemia abdominal obesity animal protein protein intake Alpha-linolenic acid docosahexaenoic acid rumenic acid punicic acid enriched eggs waist circumference obesity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069903321 |
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Chiva-Blanch Gemma
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Hallmarks of Parkinson’s Disease
| Hallmarks of Parkinson’s Disease |
| Autore | Alves Da Costa Cristine |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (124 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
Parkinson’s disease
unfolded protein response reticulum endoplasmic genetics alpha-synuclein prion-like spreading cell-to-cell transfer neurodegeneration mitochondrial dysfunction PINK1 neurons astrocytes microglia α-synuclein exocytosis lipids membranes Parkinson disease SNARE complex synapse vesicle fusion therapeutic target protein quality control mitochondrial quality control ubiquitin alpha-syn mitophagy Parkin mito-Keima mito-QC mito-SRAI |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069503321 |
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Alves Da Costa Cristine
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Impaired Mitochondrial Bioenergetics under Pathological Conditions
| Impaired Mitochondrial Bioenergetics under Pathological Conditions |
| Autore | Lenaz Giorgio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (460 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
aging heart
Bcl-2 family mitochondria programmed cell death fatty acid oxidation palmitate oleate m.3243A> G mutation MT-ATP6 m.8909T> C ATP synthase nephropathy oxidative phosphorylation mitochondrial disease cardiolipin Barth syndrome Sengers syndrome respiratory chain Dilated Cardiomyopathy with Ataxia cardiomyopathy mammalian complex I NADH dehydrogenase complex I assembly complex I structure complex I deficiency supernumerary subunits electron transport chain mitochondrial dysfunction Leigh syndrome mitochondrial diseases yeast Saccharomyces cerevisiae pet mutants pancreatic endocrine cells mathematical model cellular bioenergetics diabetes glucagon insulin exercise immune system metabolic disease COVID-19 mitochondrial dynamics viral infections MAVS RIG-I MDA5 innate immune response SARS CoV-2 RSV influenza respiratory supercomplexes ROS ATP synthase/hydrolase mitochondrial permeability transition pore cristae cellular signaling human disease mitochondrial dynamic cell signaling cancer respiratory complexes oxidative stress mitochondrial DNA MTCYB mutations cytochrome b complex III aging energy metabolism entorhinal cortex lipoxidation-derived damage neurodegeneration oxidative damage protein import respiratory complex assembly supercomplexes mitochondrial proteostasis heart failure bioenergetics assembly factor atypical myopathy high-resolution respirometry toxicity assays cell culture equine primary myoblasts fibroblasts frozen tissue leukocytes oxygen consumption platelets respirometry skeletal muscle |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585934503321 |
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Lenaz Giorgio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
apoptosis
fucoidan hepatocellular carcinoma reactive oxygen species 3-alkylpyridinium polymers nicotine nicotinic acetylcholine receptor non-small cell lung carcinoma melanoma sinulariolide proteomic mitochondria caspase cascade marine fungus sediment anthranilic acid Penicillium paneum cytotoxicity dibromotyrosine mitochondrial dysfunction oxidative stress topoisomerase epigonal organ bonnethead shark Jurkat tumor cell line hippuristanol PEL AP-1 STAT3 Akt colorectal cancer marine mollusc brominated indoles shrimp chemoprevention fatty acids carotenoids cancer nanoparticle osteosarcoma lung metastasis elisidepsin lipid rafts hydroxylated lipids fatty acid 2-hydroxylase cooperative binding membrane permeabilization marine organisms polysaccharides anticancer anticarcinogenic mechanisms of action fumigaclavine C anti-proliferation mitochondrial pathway anti-cancer anti-proliferative carotenoid cell cycle arrest fucoxanthin azoxymethane bioactive natural product isatin in vivo model Marthasterias glacialis L. palmitic acid ER-stress CHOP Antibody Drug Conjugates (ADCs) marine antitumor agents clinical trials approved antitumor agents AD0157 angiogenesis marine drug pyrrolidinedione secondary metabolites cancer preventive chemopreventive trabectedin plitidepsin tumor-associated macrophages tumor microenvironment preclinical anticancer immunity antiangiogenesis fascaplysin cyclin-dependent kinase small cell lung cancer camptothecin poly(ADP-ribose)-polymerase inhibitor breast cancer seaweed therapeutic compounds autophagy marine drugs autophagy inhibitors autophagy inducers macrolide programmed cell death energy stress araguspongine C c-Met HER2 gemcitabine pazopanib phase I safety soft tissue sarcoma pachastrissamine jaspine B carbocyclic analogue sphingosine kinase inhibitor molecular modeling ET-743 DNA minor groove binder soft tissue sarcoma chemotherapy bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) anti-metastatic activity cell adhesion β1-integrin FAK BEL-7402 cell triterpene glycosides sea cucumbers antitumor activities arrest of cell cycle antibacterial marangucyclines deep-sea Streptomyces sp. SCSIO 11594 LS-1 SNU-C5/5-FU TGF-β signaling carcinoembryonic antigen kalkitoxin Moorea producens mitochondria toxin VEGF angiogenesis inhibitor hypoxia-inducible factor-1 HIF-1 Lyngbya majuscula marine metabolites SZ-685C nonfunctioning pituitary adenomas Ecklonia cava phlorotannins dieckol migration sipholenol A ABC transporter multidrug resistance P-gp/ABCB1 BCRP/ABCG2 MRP1/ABCC1 marine natural products glioblastoma xyloketal B proliferation TRPM7 marine compound ribosomal protein genes snoRNA FAU RPS30 SNORA62 evolution Porifera Penicillium brevicompactum Brevianamide Mycochromenic acid derivative antifouling Caribbean sponge plakortide endoperoxide leukemia multi-drug resistant leukemia Sarcophyton ehrenbergi soft coral terpenes cembranoids cytotoxic activity molecular docking uveal melanoma oxidative stress virtual screening Topo I inhibitor low toxic natural product Ulva fasciata selenium-containing polysaccharide-protein complex pseudopterosin NF-κB p65 inflammation cytokine release IL-6 TNFα MCP-1 glucocorticoid receptor paulomycins Micromonospora antitumor Cantabrian Sea-derived actinobacteria puupehenones sponges antiangiogenic antitumoral porifera/sponge cancer genes molecular oncology bromophenol molecular mechanisms cell cycle PI3K/Akt p38/ERK ROS human lung cancer glycosaminoglycans antiproliferative heparan sulphate gliotoxin NSCLC adriamycin resistance Sepia ink polysaccharides antitumour chemosensitization anticoagulation sea anemone drug discovery endothelial cells RGD motif kunitz type inhibitor prostate cancer antioxidant natural marine compounds marine biotechnology microalgae marine sponges Aeroplysinin Isofistularin pheochromocytoma and paraganglioma metastasis cancer progression cell adhesion molecules integrin β1 hypoxia phycocyanin non-small cell lung cancer NF-κB signaling marine-derived drugs bioanalysis chromatography manzamine A epithelial-mesenchymal transition lung cancer circulating tumor cells signal transduction cisplatin Lampetra morii buccal gland cystatin F anti-angiogenesis cystatin superfamily Antimicrobial peptide (AMP) Tilapia piscidin 4 (TP4) non-small cell lung cancer (NSCLC) itampolin A FBDD p38α novel inhibitor tetracenomycin X cyclin D1 proteasomal degradation p38 c-JUN λ-carrageenan heparanase anticoagulant depolymerisation cell migration Aspergillus naphthopyrones endophytic fungus Leathesia nana mangrove-derived actinomycete ansamycins divergolides apoptosis-inducing activity actinomycin EMT invasion low molecular weight fucoidan extract N-Ras neuroblastoma-rat sarcoma Cancer programmed cell death-ligand 1 programmed cell death-ligand 2 human sarcoma cell line (HT1080 cells) human normal diploid fibroblast (TIG-1 cells) chimera chemical conjugation anticancer agent hybridization α9-nicotinic acetylcholine receptors (nAChRs) breast cancer cells αO-conotoxin GeXIVA targeted therapy gorgonian Leptogorgia humulane sesquiterpenoids anticancer activity 12-deacetyl-12-epi-scalaradial HeLa cells Nur77 MAPK/ERK pathway Mycalin A C15 acetogenins synthetic analogues antiproliferative activity A375 and HeLa cell lines polyoxygenated steroids sponge Haliclona gracilis Thalassia testudinum thalassiolin B polyphenols CYP1A1 benzo[a]pyrene JNK1/2 natural products synergism A549 cells cytoskeleton P2X7 receptor pollution anti-angiogenic gene expression HSP90 inhibitor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metabolomics in Neurodegenerative Disease
| Metabolomics in Neurodegenerative Disease |
| Autore | Green Brian |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (184 p.) |
| Soggetto non controllato |
glutamic acid
direct mass spectrometry neurodegeneration 6-OHDA targeted mass spectrometry mitochondrial dysfunction myo-inositol metabolomics bile acids subacute mild traumatic brain injury age-related macular degeneration metabolic pathways energy metabolism midbrain Alzheimer's disease biomarkers 1H NMR Parkinson's disease dementia GC-MS pathogenesis tricarboxylic acid cycle micro-dialysis 13C-labeled succinate metabolism lipidomics dementia with Lewy bodies fatty acid prodromal Parkinson's disease malonate cerebral ischemia mass spectrometry retinal pigment epithelium excitotoxicity endothelin-1 reperfusion C. elegans Streptomyces venezuelae ?-synuclein aggregates natural product fatty acid metabolism imaging mass spectrometry LC-MS drusen cerebral palsy plasma Parkinson's disease |
| ISBN | 3-03928-041-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087203321 |
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Green Brian
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondria in Health and Diseases
| Mitochondria in Health and Diseases |
| Autore | Javadov Sabzali |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (434 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
hypoglycemia
sodium dichloroacetate pyruvate dehydrogenase kinase pyruvate dehydrogenase oxidative stress neuron death cholangiocellular carcinoma mitochondria energy metabolism oxidative phosphorylation 4-HNE DRP1 ERK1/2 hippocampus JNK mitochondrial dynamics PKA protein phosphatases TUNEL DDE high-fat diet mitochondrial UCP2 ROS antioxidant system uncoupling protein mitochondria: energy metabolism lipid handling fatty acid oxidation potassium channel reactive oxygen species antioxidants life span aging BKCa channels pravastatin gemfibrozil liver colon mitochondrial function cyclosporin A mitochondria calcium buffering mitochondria bioenergetics mitochondria permeability transition pore inorganic phosphate hepatic fibrogenesis HtrA2/Omi reactive oxygen species stress mitochondrial homeostasis complex I (CI) deficiency metabolome and proteome profiling reactive oxygen species (ROS) respirasome assembly electron tunneling (ET) perilipin 5 lipid droplet H9c2 cardiomyoblasts adenine nucleotide translocase respiratory supercomplexes ETC complexes dentate granule cell epilepsy hyperforin LONP1 neuroprotection pilocarpine seizure siRNA cardioprotection mitochondrial permeability transition pores mitochondrial connexin 43 cardiolipin iron overload hepcidin transferrin ferritin ZIP inflammation mtDNA mitochondrial dysfunction muscle aging physical performance LHON Siberian population ancient mutation specific genetic background apoptosis human amniotic membrane mitochondrial cell death BAX BCL-2 tensile strength mitochondrial gene expression mtDNA transcription mtRNA post-transcriptional mtRNA processing dsRNA innate immunity interferon response amino acid neurotransmitter cerebellar amino acid metabolism hypoxia 2-oxoglutarate dehydrogenase tricarboxylic acid cycle heart cytoskeletal proteins mitochondrial interactions plectin tubulin beta signaling GW9662 ischemia reperfusion injury Langendorff myocardial pioglitazone redox state rosiglitazone TZD uncoupling ADP/ATP carrier KmADP dextran morphology cardiomyocytes telomere length telomerase activity development regeneration intranuclear mitochondria healthy cells electron and confocal microscopy signaling pathways ion homeostasis human diseases |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557577203321 |
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Javadov Sabzali
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondrial Dysfunction and Neurodegeneration
| Mitochondrial Dysfunction and Neurodegeneration |
| Autore | Tapias Victor |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (209 p.) |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
mitochondrial dysfunction
quality control neurodegenerative diseases Parkinson's disease Alzheimer's disease |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557387303321 |
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Tapias Victor
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondrial Dysfunction in Aging and Diseases of Aging
| Mitochondrial Dysfunction in Aging and Diseases of Aging |
| Autore | Haas Richard H |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (270 p.) |
| Soggetto non controllato |
age-related diseases
sphingolipids glaucoma ALS neurodegeneration mitochondrial dysfunction adaptive immunity senescence de-emergence innate immunity cell danger response mitochondrial transfer axonal transport cytokines mitochondrial age-related macular degeneration prevention heart failure purinergic signaling autophagy Alzheimer's disease diabetic retinopathy proteostasis 1 immunosenescence Miro1 ROS metabolism optic nerve polypharmacy eIF2? Parkin coenzyme Q10 neurodegenerative disease DNA damage skin exercise nucleotide metabolism pasteur effect stress response inflammation retina drug-induced mitochondrial toxicity neuroinflammation exosomes reactive oxygen species 25(OH)D cardiomyopathy crabtree effect insulin resistance cardiovascular disease ageing genetic mutations metabokines mitochondria multiple sclerosis aerobic healing cycle SOD1 mitophagy PINK1 type 2 diabetes integrated cell stress response morbidity and mortality ultraviolet photoageing cancer aging 25(OH)2D lysosome NAD+ Parkinson's disease |
| ISBN | 3-03921-328-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756303321 |
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Haas Richard H
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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