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Impaired Mitochondrial Bioenergetics under Pathological Conditions
| Impaired Mitochondrial Bioenergetics under Pathological Conditions |
| Autore | Lenaz Giorgio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (460 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
aging heart
Bcl-2 family mitochondria programmed cell death fatty acid oxidation palmitate oleate m.3243A> G mutation MT-ATP6 m.8909T> C ATP synthase nephropathy oxidative phosphorylation mitochondrial disease cardiolipin Barth syndrome Sengers syndrome respiratory chain Dilated Cardiomyopathy with Ataxia cardiomyopathy mammalian complex I NADH dehydrogenase complex I assembly complex I structure complex I deficiency supernumerary subunits electron transport chain mitochondrial dysfunction Leigh syndrome mitochondrial diseases yeast Saccharomyces cerevisiae pet mutants pancreatic endocrine cells mathematical model cellular bioenergetics diabetes glucagon insulin exercise immune system metabolic disease COVID-19 mitochondrial dynamics viral infections MAVS RIG-I MDA5 innate immune response SARS CoV-2 RSV influenza respiratory supercomplexes ROS ATP synthase/hydrolase mitochondrial permeability transition pore cristae cellular signaling human disease mitochondrial dynamic cell signaling cancer respiratory complexes oxidative stress mitochondrial DNA MTCYB mutations cytochrome b complex III aging energy metabolism entorhinal cortex lipoxidation-derived damage neurodegeneration oxidative damage protein import respiratory complex assembly supercomplexes mitochondrial proteostasis heart failure bioenergetics assembly factor atypical myopathy high-resolution respirometry toxicity assays cell culture equine primary myoblasts fibroblasts frozen tissue leukocytes oxygen consumption platelets respirometry skeletal muscle |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585934503321 |
Lenaz Giorgio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondria-targeted drug delivery
| Mitochondria-targeted drug delivery |
| Autore | Kopecka Joanna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (290 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
retinal ischemia
blood-brain barrier endothelial reactive oxygen species oxidative stress tunneling nanotubules neuron central nervous system inflammation hypoxia anticancer peptide (ACP) antimicrobial peptide (AMP) anticancer peptides antimicrobial peptides host defense peptides prediction random forest mitochondria mitochondrial DNA mitochondrial disorders pharmacological therapy gene therapy precision medicine cardiovascular disease drug delivery mitochondria dysfunctions nanocarriers oxoglutarate carrier malate-aspartate shuttle cancer metabolism ATP production diphenyleneiodonium NADPH-oxidase differentiation proliferation mitochondria-targeted antioxidants LPS mitochondrial ROS antitumor agents fluorescence lifetime imaging medicinal chemistry metabolic drug mitochondrial carrier melanoma plumbagin cytotoxic effect metabolism cholesterol lipid raft mitochondrial permeability transition pore alkylphospholipid analog edelfosine mitochondrial oncometabolites cancer drug resistance mitochondrial disease heteroplasmy mitochondrial gene delivery |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576881503321 |
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Kopecka Joanna
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondria: From Physiology to Pathology
| Mitochondria: From Physiology to Pathology |
| Autore | Bruni Francesco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
atherosclerosis
carotid intima-media thickness mitochondrial mutations cardiovascular risk factors mitochondria mtDNA cristae mitochondrial fission mitochondrial fusion mitochondrial diseas mitochondrial dynamics mitoenergetics mitosteroidogenesis LH cAMP Leydig cell mitochondrial DNA segregation heteroplasmy selective elimination mitophagy mitochondrial engineered nucleases kinases phosphorylation disease PINK1 Parkinson's disease mitochondria homeostasis Cterm MELAS transmitochondrial cybrids aminoacyl-tRNA synthetases LARS2 mitochondrial disease therapeutic peptides FAD synthase FAD1 mitochondria localization Saccharomyces cerevisiae mRNA mitochondrial localization motif |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Mitochondria |
| Record Nr. | UNINA-9910557757603321 |
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Bruni Francesco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondrial Transport Proteins
| Mitochondrial Transport Proteins |
| Autore | Palmieri Ferdinando |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (476 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
hypoxia
resistance to hypoxia mitochondria mitochondrial calcium transport mitochondrial calcium uniporter complex mitochondrial Ca2+-induced permeability transition pore cyclophilin D ATP synthase disease error of metabolism mitochondrial carrier mitochondrial carrier disease mitochondrial disease mitochondrial transporter membrane transport mutation SLC25 mitochondrial permeability transition apoptosis necrosis ischemia/reperfusion cancer neurodegeneration cyclosporin A metabolite transport mitochondrial pyruvate carrier sideroflexin TOM TIM chaperones TIM22 protein translocation mitochondrial biogenesis amino acid biological function ion inner mitochondrial membrane mitochondrial carrier family organic acid substrate specificity transport mechanism vitamin USMG5/DAPIT glucose-stimulated insulin secretion glucose-induced expression membrane subunits of ATP synthase ATP synthase oligomers mitochondrial cristae morphology metabolism metabolic disorders adult-onset type II citrullinemia (CTLN2) aspartate/glutamate carrier (AGC) animal model argininosuccinate synthetase (ASS) aversion to carbohydrates citrin food taste neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) protein–protein interaction MPC lifespan pyruvate metabolism mitochondrial transport peroxisomes carrier cofactor ABC transporter aquaporin ion channels potassium channels ATP calcium ROS potassium channel openers MCF function plant metabolism plant development diseases VDAC1 virus pancreatic islets β-cell diabetes glucotoxicity glucolipotoxicity lipotoxicity mitochondrial carriers SLC transporters SLC54 SLC55 LETM SLC56 sequence analysis protein targeting Voltage-Dependent Anion selective Channel isoforms oxidative post-translational modification gene promoter yeast bioenergetics SLC25A1 CIC CTP citrate inflammation 22.q11.2 NAFLD/NASH carnitine carnitine acyl-carnitine carrier carnitine acyl-carnitine translocase post-translational modification solute carrier family 25 SLC25A20 MCU mitochondrial Ca2+ uniporter Ca2+ signaling mitochondrial metabolism skeletal muscle mitochondria SLC25A51 NAD+ transporters NAD electrophysiology ATP-dependent potassium channel |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566465303321 |
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Palmieri Ferdinando
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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