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Mitochondrial Dysfunction in Aging and Diseases of Aging
| Mitochondrial Dysfunction in Aging and Diseases of Aging |
| Autore | Haas Richard H |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (270 p.) |
| Soggetto non controllato |
age-related diseases
sphingolipids glaucoma ALS neurodegeneration mitochondrial dysfunction adaptive immunity senescence de-emergence innate immunity cell danger response mitochondrial transfer axonal transport cytokines mitochondrial age-related macular degeneration prevention heart failure purinergic signaling autophagy Alzheimer's disease diabetic retinopathy proteostasis 1 immunosenescence Miro1 ROS metabolism optic nerve polypharmacy eIF2? Parkin coenzyme Q10 neurodegenerative disease DNA damage skin exercise nucleotide metabolism pasteur effect stress response inflammation retina drug-induced mitochondrial toxicity neuroinflammation exosomes reactive oxygen species 25(OH)D cardiomyopathy crabtree effect insulin resistance cardiovascular disease ageing genetic mutations metabokines mitochondria multiple sclerosis aerobic healing cycle SOD1 mitophagy PINK1 type 2 diabetes integrated cell stress response morbidity and mortality ultraviolet photoageing cancer aging 25(OH)2D lysosome NAD+ Parkinson's disease |
| ISBN | 3-03921-328-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756303321 |
Haas Richard H
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Biomarkers in Alzheimer's Disease
| Novel Biomarkers in Alzheimer's Disease |
| Autore | Villa Chiara |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (442 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
flotillin
Alzheimer's disease biomarker exosomes beta-amyloid Tau aging biomarkers cytokines cognitive decline metabolomics neuroinflammation multivariate analysis physical performance person-tailored PET/CT (18F)FDG neuropsychological assessment APP mutations APOE alleles PSEN1 PSEN2 germline mutations late onset AD early onset AD familial AD genetics of AD mitochondrial spare respiratory capacity mitochondrial membrane potential glycolytic reserve semantic memory phonemic fluency episodic memory neuropsychology neuroimaging mild cognitive impairment EEG TMS obesity diabetes inflammation Amyloid Beta mitochondrial dysfunction nutrition omega-3 fatty acids antioxidant carotenoids vitamin E cognition older adults ageing subjective cognitive decline clock genes Clock ApoE cardiovascular risk factors Alzheimer disease semantic priming amyloid beta cerebrospinal fluid amyloid beta peptide total tau phosphorylated tau diagnosis drug development clinical trials diagnostic research virus bacteria dementia blood behavioral and psychological symptoms of dementia (BPSD) Alzheimer's disease (AD) neuropsychiatry inventory scale (NPI) endophenotypes CART analysis MTHFR APOE COMT genetic variants early diagnosis biofluids amyloid cascade hypothesis glucose metabolism adipose tissue dysfunction energetic metabolism lysosomes dysfunction Type-3-Diabetes neurodegeneration amyloid tau soluble TREM2 NfL Multiplex SiMoA diagnostics messenger RNA microRNA neurotropic microbes precision medicine prognostics synaptic biomarkers neurofilament light chain |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557129403321 |
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Villa Chiara
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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