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A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder
| A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder |
| Autore | Frye Richard E |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (416 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
acyl-carnitines
ADHD amygdala anxiety Array-Comparative Genomic Hybridization (Array-CGH) ASD associated risk autism autism spectrum disorder autism spectrum disorder (ASD) autism spectrum disorders autonomic disorder B12 biomarker brain brain development cerebral folate deficiency children chromosomal microarray analysis clinical decision support tool clinical utility cobalamin concomitant condition copy number variants cortisol COVID-19 cytokines digital biomarkers disorder Ehlers-Danlos syndrome energy metabolism epigenetics fatty acid oxidation fecal metabolites females fetal development Fisher Discriminant Analysis flavonoids folate receptor alpha folate receptor alpha autoantibodies folates folinic acid gastrointestinal symptoms genetic testing genomics glutathione heart rate variability hypermobility spectrum disorders immune dysfunction immunoglobulin G inflammation integrative intervention intravenous immunoglobulin leucovorin locked-in network syndrome logistic regression analysis luteolin mast cell activation syndrome mast cells medical claims metabolomics methylation methylcobalamin microbiome microglia minerals mitochondria model monoamine neurotransmitters n/a network connectivity neuromodulation neurostimulation neurotransmitter deficiency non-linear complex dynamics nutraceuticals OCD omics oxidative stress PANDAS parents patient stratification personalized treatment strategy polygenic risk scores precision medicine pregnancy prenatal environment proteomics quality of life redox metabolism resting-state functional magnetic resonance imaging resveratrol retrospective analysis SARS-CoV-2 single nucleotide polymorphisms sleep anxiety social dyads socio-motor parameters stochastic analysis stress survey systematic review Temple Grandin temporal lobe epilepsy time series analysis transcriptomics transdermal electrical neuromodulation vitamins wearables whole exome sequencing whole genome sequencing α-amylase |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595075503321 |
Frye Richard E
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Forensic Genetics
| Advances in Forensic Genetics |
| Autore | Morling Niels |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (516 p.) |
| Soggetto topico |
Biology, life sciences
Genetics (non-medical) Research & information: general |
| Soggetto non controllato |
1000 Genomes
activity activity issues activity level activity level evaluation ancestry ancestry informative markers ancestry prediction ancient DNA animal forensics authorized Bayesian networks bio-geographical ancestry biogeographic ancestry biological sexing biostatistics body fluid bone burglary canine DNA phenotyping cat STRs classification cleaning strategies clustering clustering algorithm CODIS COI communication consensus profile crime scene cross-amplification cyt b database decision-making decontamination degraded DNA DEPArray distance based DNA DNA forensics DNA methylation DNA mixture DNA molecules DNA persistence DNA phenotyping DNA prevalence DNA recovery DNA transfer DNA-based prediction DNAStatistX dog STRs domestic dog (Canis familiaris) ethics ethics as lived practice EuroForMix evaluative evidence externally visible characteristics eye colour FDP forensic forensic DNA intelligence forensic DNA phenotyping forensic DNA profiling forensic DNA typing forensic epigenetics forensic genealogy forensic genetics forensic genomics forensic microbiology forensic science genetic databasing heteroplasmy HIrisPlex-S human genome variation human identification Human Origins SNP array hybridization capture hypothesis tests identification illegal trade investigative investigative leads kinship kinship analyses likehood low template DNA LR ltDNA massively parallel sequencing massively parallel sequencing (MPS) microbiome microsatellites mitochondria mitochondrial DNA mixture deconvolution mixture interpretation mRNA mtDNA next generation sequencing next generation sequencing (NGS) next-generation sequencing next-generation sequencing (NGS) nocturnal raptors number of contributors OpenArray™ system organ persistence phenotype prediction physical appearance pigmentation principles of interpretation probabilistic genotyping proof of concept study propositions reporting review Romanov family rs12913832 sampling sequence analysis short tandem repeat short tandem repeat (STR) single nucleotide polymorphism (SNP) single-cell single-cell genomics single-cell sequencing skin color SNP SNPs software Strigiformes STRmixTM TaqMan SNP genotyping tissue touch DNA transfer wildlife forensics Y-STR |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585942303321 |
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Morling Niels
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Metabolic Mechanisms of Aging and Its Related Diseases
| Advances in Metabolic Mechanisms of Aging and Its Related Diseases |
| Autore | Aquilano Katia |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (119 p.) |
| Soggetto topico |
Physiology
Science: general issues |
| Soggetto non controllato |
aminoacid metabolism
glucose metabolism lipid metabolism mitochondria oxidative stress senescence signaling |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557712903321 |
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Aquilano Katia
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Aging and Age-Related Disorders : : From Molecular Mechanisms To Therapies / / Vladimir Titorenko
| Aging and Age-Related Disorders : : From Molecular Mechanisms To Therapies / / Vladimir Titorenko |
| Autore | Titorenko Vladimir |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (322 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
advanced glycated end products
microRNAs differentiation transcription skin absorption cellular quiescence lifespan longevity genes protein kinases self-renewal circadian blood-brain barrier aging-related disorders sirtuin-1 inflammation arterial aging reactive oxygen species electron microscopy reconstructed human skin rejuvenation low-dose fluvastatin and valsartan combination inflammaging hematopoietic stem cell aging cell cycle mitochondria ribose the nervous system nanomedicine proteostasis adult stem cells immunosenescence cell signaling mechanisms of quiescence maintenance metabolism aging melatonin diabetes mechanisms of quiescence entry and exit Drosophila melanogaster GSK3 (glycogen synthase kinase 3) |
| ISBN |
9783039213566
3039213563 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367567903321 |
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Titorenko Vladimir
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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AMP-Activated Protein Kinase Signalling
| AMP-Activated Protein Kinase Signalling |
| Autore | Neumann Dietbert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (452 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
?-linker
?RIM 2-methoxyestradiol 3T3-L1 A769662 acetyl-CoA activation loop adaptive thermogenesis adenosine monophosphate-activated protein kinase adherent junctions adipocyte adipose tissue AICAR AID Akt AML AMP-activated protein kinase AMP-activated protein kinase (AMPK) AMPK AMPK kinase AS160 assisted reproduction techniques atrophy autophagy beiging CaMKK2 carrier catechol-O-methyltransferase CBS cellular energy sensing chromatin remodeling CML CMML co-expression CREB developmental origins of health and disease (DOHaD) dietary fatty acids differentiation DNA methylation endothelial cells endothelial function endothelial nitric-oxide synthase energy deficiency energy metabolism energy utilization epigenetics epithelial cells exercise fatty acid oxidation fiber-type food intake gestational diabetes mellitus glucose uptake glycogen glycogen storage disease HDAC4/5 HDACs heat shock protein hepatocyte hindlimb suspension histone modification host defense hypertension hypertrophy hypothalamus IL-1? Immediate early genes indirect calorimetry infection insulin signalling ionomycin KATs kidney disease lipid metabolism liver LKB1 macrophages MDCK MDS mechanical unloading medulloblastoma membrane membranes metabolic disease metabolic-inflammation metabolism microarrays mitochondria monocytes motility motor endplate remodeling mTOR mycobacteria MyHC I(?) n/a NAD+ nectin-afadin NLRP3 nutrient-sensing signals nutrigenomics nutrition oxidative stress p70S6K par complex peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) phenylephrine phosphorylation PKA preeclampsia pregnancy proteasome protein acetylation protein kinase B protein synthesis pump regrowth renin-angiotensin system resveratrol signaling sirtuin 1 (SIRT1) skeletal muscle soleus muscle soluble Adenylyl cyclase sonic hedgehog spermatozoa steatosis stress synaptic activation TAK1 TBC1D4 tight junctions transcription transporter ULK vasoconstriction vasodilation ZO-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346858503321 |
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Neumann Dietbert
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anti-inflammatory Activity of Plant Polyphenols 2.0
| Anti-inflammatory Activity of Plant Polyphenols 2.0 |
| Autore | Dell'Agli Mario |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (120 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
anti-inflammatory
anti-oxidant anti-viral activity antioxidant enzymes antioxidants Antirhea borbonica caffeic acid cancer prevention curcumin DESI-imaging diabetes ER-stress flavonoids glioblastoma cells inflammation insulin-producing cells kidney fibrosis marine algae mechanism of action mitochondria n/a Nrf2 pathway oxidative stress p53 PERK polyphenols radiation UPR verbascoside |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576880903321 |
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Dell'Agli Mario
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Autophagy in Tissue Injury and Homeostasis
| Autophagy in Tissue Injury and Homeostasis |
| Autore | Lin Pei-Hui |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (322 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
acute kidney injury
acute lung injury aging AMPK apoptosis ATGs autophagic flux autophagy Autophagy Beclin-1 biomarkers caloric restriction cardiac dysfunction cell death cirrhosis COPD Crohn's disease cystic fibrosis diabetic nephropathy diabetic retinopathy dietary restriction endotoxemia ethanol exercise exosomes fibrosis FOXO glutaminase HCC therapy hepatic stellate cells hepatocellular carcinoma hepatocytes idiopathic pulmonary fibrosis immune immune cell infertility inflammasome inflammation inflammatory bowel disease inflammatory bowel diseases innate immunity intestinal homeostasis ischemia kidney diseases LC3 lysosomal damage macrophage macrophages metabolism mitochondria mitophagy molecular rehabilitation mTOR MTOR muscle regeneration n/a neuronal cell death Notoginsenoside R1 oxidative stress PAH Paneth cell parkin Parkin PINK1 renal tubular cells senescence sepsis Sertoli cell sinusoidal endothelial cells spinal cord injury stem cell TFEB traumatic brain injury tuberculosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557284203321 |
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Lin Pei-Hui
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bacillus thuringiensis Toxins: Functional Characterization and Mechanism of Action
| Bacillus thuringiensis Toxins: Functional Characterization and Mechanism of Action |
| Autore | Bel Yolanda |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (340 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
3D-Cry toxins
3D-structure ABCC2 adhesion Aedes aegypti AFM anticancer activity Anticarsia gemmatalis antimicrobial peptide apoptosis Asian corn borer ATP-binding cassette subfamily a member 2 (ABCA2) Bacillus thuringiensis Bacillus thuringiensis proteins bioassay biological control Bombyx mori Bti cadherin chitin-binding protein coleopteran pests CRISPR/Cas9 Cry Cry1Ab Cry1Ac resistance Cry1Fa Cry2Ab toxin Cyt Cyt2Aa2 toxin erythrocyte membrane functional receptor genome editing gut microbiota HEK293T cell in vitro evolution insect resistance insecticidal activity insecticidal proteins Leptinotarsa decemlineata Lobesia botrana lysosome Mamestra brassicae membrane receptors minor proteins mitochondria mode of action mode of action of Cry toxin mosquito control n/a oligomer formation Ostrinia furnacalis Ostrinia nubilalis parasporins peritrophic matrix Plutella xylostella protein-lipid binding protoxin activation pyramids QCM-D rational design resistance S-layer proteins Sf21 cell line Sf9 cells Sip site-directed mutagenesis Spodoptera frugiperda Spodoptera litura Spodoptera spp., Helicoverpa armigera structure synergy tobacco budworm toxin enhancement transcription activator-like effector-nucleases (TALENs) trypsin-like midgut protease vegetative insecticidal proteins Vip Vip3A Vip3Aa |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Bacillus thuringiensis Toxins |
| Record Nr. | UNINA-9910557646103321 |
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Bel Yolanda
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Benefits of Resveratrol Supplementation / María P. Portillo, Alfredo Fernandez-Quintela
| Benefits of Resveratrol Supplementation / María P. Portillo, Alfredo Fernandez-Quintela |
| Autore | Portillo María P |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
polyphenols
?-viniferin leptin resistance p53 kidney energy restriction grape powder extract cytokines phosphorylation obesity energy metabolism metabolic pathways endothelial function polyol pathway antioxidant caloric restriction rat adipose tissue microparticles pathways angiotensin converting enzyme 2 resistance esRAGE interleukins metabolic syndrome dissolution rate thermogenesis streptozotocin bioavailability solubility metabolism renin-angiotensin system microbiota Sirt-1 magnesium dihydroxide hypertrophy metabolic diseases physiological adaption red wine extract lens distribution MTA1 sirtuin inflammation cardiac function rats cisplatin resveratrol mitochondria breast cancer ischemia-reperfusion cardiovascular metabolites gut microbiota prostate cancer performance type 2 diabetes cafeteria diet high-fat high-sucrose diet resistance exercise aging diabetes oxidative stress |
| ISBN |
9783039212767
3039212761 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346854603321 |
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Portillo María P
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers of Oxidative Stress
| Biomarkers of Oxidative Stress |
| Autore | Akerstrom Bo |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (132 p.) |
| Soggetto topico |
Physiology
Science: general issues |
| Soggetto non controllato |
endoplasmatic reticulum
hemoglobin-/heme scavengers metabolic dysfunction mitochondria pathological mechanisms reactive oxygen species |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557306603321 |
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Akerstrom Bo
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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