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A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder
| A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder |
| Autore | Frye Richard E |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
fecal metabolites
ASD microbiome gastrointestinal symptoms Fisher Discriminant Analysis digital biomarkers wearables time series analysis autism social dyads socio-motor parameters network connectivity non-linear complex dynamics stochastic analysis autism spectrum disorders copy number variants females Array-Comparative Genomic Hybridization (Array-CGH) autism spectrum disorder Ehlers-Danlos syndrome hypermobility spectrum disorders autonomic disorder mast cell activation syndrome genetic testing chromosomal microarray analysis whole exome sequencing whole genome sequencing clinical utility polygenic risk scores Temple Grandin biomarker omics precision medicine proteomics transcriptomics epigenetics metabolomics patient stratification mitochondria oxidative stress prenatal environment immune dysfunction immunoglobulin G intravenous immunoglobulin energy metabolism fatty acid oxidation acyl-carnitines resveratrol integrative model concomitant condition disorder autism spectrum disorder (ASD) genomics personalized treatment strategy single nucleotide polymorphisms clinical decision support tool ADHD PANDAS OCD anxiety folate receptor alpha folates pregnancy brain development fetal development cobalamin glutathione methylation methylcobalamin redox metabolism locked-in network syndrome resting-state functional magnetic resonance imaging temporal lobe epilepsy amygdala brain COVID-19 children cytokines flavonoids inflammation luteolin mast cells microglia SARS-CoV-2 stress nutraceuticals survey vitamins minerals B12 folinic acid quality of life parents intervention systematic review medical claims logistic regression analysis retrospective analysis associated risk monoamine neurotransmitters neurotransmitter deficiency cerebral folate deficiency folate receptor alpha autoantibodies leucovorin α-amylase cortisol heart rate variability neuromodulation sleep anxiety transdermal electrical neuromodulation neurostimulation |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595075503321 |
Frye Richard E
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Forensic Genetics
| Advances in Forensic Genetics |
| Autore | Morling Niels |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (516 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Genetics (non-medical) |
| Soggetto non controllato |
TaqMan SNP genotyping
OpenArray™ system forensic DNA phenotyping forensic DNA typing animal forensics wildlife forensics cat STRs dog STRs cyt b COI biogeographic ancestry pigmentation skin color externally visible characteristics forensic genetics eye colour rs12913832 DNA phenotyping domestic dog (Canis familiaris) canine DNA phenotyping forensic proof of concept study evidence Y-STR mtDNA mitochondria bio-geographical ancestry massively parallel sequencing ancestry informative markers SNPs 1000 Genomes Human Origins SNP array FDP HIrisPlex-S DEPArray ancestry prediction phenotype prediction next-generation sequencing single-cell genomics single-cell sequencing mixture deconvolution low template DNA ltDNA probabilistic genotyping EuroForMix DNAStatistX STRmixTM DNA forensics DNA mixture mixture interpretation single-cell clustering algorithm number of contributors consensus profile cross-amplification microsatellites Strigiformes illegal trade kinship nocturnal raptors review body fluid organ tissue identification mRNA DNA methylation activity level massively parallel sequencing (MPS) next-generation sequencing (NGS) short tandem repeat (STR) sequence analysis software DNA transfer DNA persistence DNA prevalence DNA recovery activity level evaluation forensic science ethics ethics as lived practice decision-making genetic databasing forensic genealogy forensic epigenetics communication database SNP next generation sequencing hybridization capture bone transfer persistence activity Bayesian networks burglary CODIS touch DNA crime scene authorized sampling short tandem repeat forensic microbiology microbiome physical appearance human genome variation DNA-based prediction investigative leads forensic DNA intelligence forensic genomics degraded DNA mitochondrial DNA forensic DNA profiling ancient DNA human identification ancestry biostatistics clustering classification distance based likehood hypothesis tests DNA molecules decontamination cleaning strategies Romanov family next generation sequencing (NGS) heteroplasmy single nucleotide polymorphism (SNP) kinship analyses biological sexing DNA principles of interpretation investigative evaluative reporting LR propositions activity issues |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585942303321 |
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Morling Niels
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Metabolic Mechanisms of Aging and Its Related Diseases
| Advances in Metabolic Mechanisms of Aging and Its Related Diseases |
| Autore | Aquilano Katia |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (119 p.) |
| Soggetto topico |
Science: general issues
Physiology |
| Soggetto non controllato |
senescence
glucose metabolism lipid metabolism mitochondria oxidative stress aminoacid metabolism signaling |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557712903321 |
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Aquilano Katia
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Aging and Age-related Disorders: From Molecular Mechanisms to Therapies
| Aging and Age-related Disorders: From Molecular Mechanisms to Therapies |
| Autore | Titorenko Vladimir |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (322 p.) |
| Soggetto non controllato |
advanced glycated end products
microRNAs differentiation transcription skin absorption cellular quiescence lifespan longevity genes protein kinases self-renewal circadian blood-brain barrier aging-related disorders sirtuin-1 inflammation arterial aging reactive oxygen species electron microscopy reconstructed human skin rejuvenation low-dose fluvastatin and valsartan combination inflammaging hematopoietic stem cell aging cell cycle mitochondria ribose the nervous system nanomedicine proteostasis adult stem cells immunosenescence cell signaling mechanisms of quiescence maintenance metabolism aging melatonin diabetes mechanisms of quiescence entry and exit Drosophila melanogaster GSK3 (glycogen synthase kinase 3) |
| ISBN | 3-03921-356-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Aging and Age-related Disorders |
| Record Nr. | UNINA-9910367567903321 |
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Titorenko Vladimir
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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AMP-Activated Protein Kinase Signalling
| AMP-Activated Protein Kinase Signalling |
| Autore | Neumann Dietbert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (452 p.) |
| Soggetto non controllato |
HDACs
transcription epigenetics spermatozoa par complex A769662 MDCK skeletal muscle AID phosphorylation energy metabolism monocytes autophagy CML liver hindlimb suspension pregnancy preeclampsia gestational diabetes mellitus CaMKK2 assisted reproduction techniques nutrient-sensing signals sonic hedgehog protein acetylation glycogen storage disease AMPK adenosine monophosphate-activated protein kinase AICAR indirect calorimetry IL-1? MyHC I(?) HDAC4/5 endothelial cells infection hepatocyte p70S6K lipid metabolism host defense exercise kidney disease heat shock protein ?RIM mycobacteria activation loop developmental origins of health and disease (DOHaD) CREB TAK1 metabolic-inflammation phenylephrine AMP-activated protein kinase (AMPK) KATs 2-methoxyestradiol DNA methylation NLRP3 pump ?-linker steatosis AMPK kinase stress endothelial nitric-oxide synthase vasodilation adherent junctions epithelial cells glycogen Akt synaptic activation cellular energy sensing glucose uptake transporter co-expression atrophy nutrigenomics motility vasoconstriction fatty acid oxidation oxidative stress AS160 membrane histone modification sirtuin 1 (SIRT1) chromatin remodeling insulin signalling dietary fatty acids ULK CMML adaptive thermogenesis mTOR MDS mechanical unloading AML endothelial function medulloblastoma PKA adipose tissue NAD+ membranes nutrition ZO-1 TBC1D4 adipocyte soluble Adenylyl cyclase metabolism renin-angiotensin system energy utilization proteasome differentiation signaling peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) hypertrophy AMP-activated protein kinase metabolic disease LKB1 soleus muscle macrophages Immediate early genes CBS benign motor endplate remodeling ionomycin nectin-afadin tight junctions resveratrol protein kinase B regrowth mitochondria protein synthesis energy deficiency catechol-O-methyltransferase fiber-type microarrays carrier acetyl-CoA hypertension 3T3-L1 hypothalamus food intake |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346858503321 |
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Neumann Dietbert
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anti-inflammatory Activity of Plant Polyphenols 2.0
| Anti-inflammatory Activity of Plant Polyphenols 2.0 |
| Autore | Dell'Agli Mario |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (120 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
flavonoids
inflammation p53 cancer prevention Nrf2 pathway anti-oxidant verbascoside polyphenols insulin-producing cells diabetes UPR oxidative stress ER-stress PERK anti-inflammatory mitochondria antioxidants marine algae anti-viral activity mechanism of action Antirhea borbonica kidney fibrosis caffeic acid antioxidant enzymes DESI-imaging curcumin glioblastoma cells radiation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576880903321 |
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Dell'Agli Mario
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Autophagy in Tissue Injury and Homeostasis
| Autophagy in Tissue Injury and Homeostasis |
| Autore | Lin Pei-Hui |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (322 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
aging
dietary restriction acute kidney injury mitochondria autophagy mitophagy ischemia renal tubular cells diabetic nephropathy exosomes mTOR innate immunity immune cell inflammasome Paneth cell inflammatory bowel disease Crohn's disease hepatocytes hepatic stellate cells sinusoidal endothelial cells macrophages fibrosis cirrhosis hepatocellular carcinoma biomarkers cell death glutaminase metabolism molecular rehabilitation kidney diseases oxidative stress inflammation ATGs intestinal homeostasis inflammatory bowel diseases HCC therapy Autophagy acute lung injury idiopathic pulmonary fibrosis COPD tuberculosis PAH cystic fibrosis Beclin-1 cardiac dysfunction sepsis endotoxemia muscle regeneration stem cell immune macrophage senescence exercise caloric restriction diabetic retinopathy PINK1 Notoginsenoside R1 ethanol LC3 apoptosis Sertoli cell Parkin TFEB infertility AMPK FOXO MTOR parkin spinal cord injury traumatic brain injury autophagic flux neuronal cell death lysosomal damage |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557284203321 |
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Lin Pei-Hui
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bacillus thuringiensis Toxins: Functional Characterization and Mechanism of Action
| Bacillus thuringiensis Toxins: Functional Characterization and Mechanism of Action |
| Autore | Bel Yolanda |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (340 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
Bacillus thuringiensis
Plutella xylostella Cry1Ac resistance trypsin-like midgut protease protoxin activation Spodoptera spp., Helicoverpa armigera Mamestra brassicae Anticarsia gemmatalis Ostrinia furnacalis Cry2Ab toxin Bombyx mori ATP-binding cassette subfamily a member 2 (ABCA2) genome editing transcription activator-like effector-nucleases (TALENs) HEK293T cell functional receptor Vip3Aa lysosome mitochondria apoptosis Sf9 cells Cry1Ab oligomer formation Sf21 cell line Ostrinia nubilalis Lobesia botrana Leptinotarsa decemlineata bioassay Cyt2Aa2 toxin protein-lipid binding erythrocyte membrane AFM QCM-D Asian corn borer ABCC2 CRISPR/Cas9 Cry1Fa resistance chitin-binding protein adhesion peritrophic matrix Vip3A Spodoptera litura site-directed mutagenesis Cry Cyt parasporins S-layer proteins Vip Sip membrane receptors insecticidal activity anticancer activity Aedes aegypti minor proteins synergy mosquito control Bti Spodoptera frugiperda cadherin mode of action of Cry toxin insecticidal proteins insect resistance tobacco budworm Bacillus thuringiensis proteins coleopteran pests structure mode of action 3D-structure biological control antimicrobial peptide gut microbiota vegetative insecticidal proteins pyramids 3D-Cry toxins in vitro evolution rational design toxin enhancement |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Bacillus thuringiensis Toxins |
| Record Nr. | UNINA-9910557646103321 |
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Bel Yolanda
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Benefits of Resveratrol Supplementation
| Benefits of Resveratrol Supplementation |
| Autore | Fernandez-Quintela Alfredo |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto non controllato |
polyphenols
?-viniferin leptin resistance p53 kidney energy restriction grape powder extract cytokines phosphorylation obesity energy metabolism metabolic pathways endothelial function polyol pathway antioxidant caloric restriction rat adipose tissue microparticles pathways angiotensin converting enzyme 2 resistance esRAGE interleukins metabolic syndrome dissolution rate thermogenesis streptozotocin bioavailability solubility metabolism renin-angiotensin system microbiota Sirt-1 magnesium dihydroxide hypertrophy metabolic diseases physiological adaption red wine extract lens distribution MTA1 sirtuin inflammation cardiac function rats cisplatin resveratrol mitochondria breast cancer ischemia-reperfusion cardiovascular metabolites gut microbiota prostate cancer performance type 2 diabetes cafeteria diet high-fat high-sucrose diet resistance exercise aging diabetes oxidative stress |
| ISBN | 3-03921-276-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346854603321 |
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Fernandez-Quintela Alfredo
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers of Oxidative Stress
| Biomarkers of Oxidative Stress |
| Autore | Akerstrom Bo |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (132 p.) |
| Soggetto topico |
Science: general issues
Physiology |
| Soggetto non controllato |
reactive oxygen species
pathological mechanisms mitochondria hemoglobin-/heme scavengers endoplasmatic reticulum metabolic dysfunction |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557306603321 |
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Akerstrom Bo
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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