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Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy : Future Perspectives
| Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy : Future Perspectives |
| Autore | Vermehren Charlotte |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (224 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
acute kidney injury
early biomarker plasma neutrophil gelatinase-associated lipocalin soluble urokinase plasminogen activator receptor medication optimization older patients emergency department multimorbidity polypharmacy potentially inappropriate medication use older adults prevalence determinants chronic outpatient 2019 Beers criteria Ethiopia pharmacogenomics persons with diabetes drug–drug interactions drug–gene interactions cytochrome P450 SLCO1B1 drug interaction checkers adverse drug reactions pharmacogenetics personalized medicine phenprocoumon DOACs bleeding thromboembolism HLA drug hypersensitivity abacavir allopurinol flucloxacillin antiepileptic drugs cost-effectiveness shared medication record medication reconciliation drug information service hospital pharmacy service electronic prescribing electronic medical record clinical pharmacist CYP2D6 CYP2D7P CYP2D8P copy number variation CNV genotyping 5’nuclease assay HRM high resolution melting drug metabolization extracellular vesicles exosomes microvesicles pharmacogene expression medication review deprescriptions quality of life aged aged, 80 and over nursing homes deprescribing medication-based risk score health outcomes cytochromes CYP1A2 adverse drug reaction antipsychotics olanzapine clozapine loxapine children youth digital decision-support health services research general practice process evaluation antidepressants utility population-based appropriateness medication adherence digital health |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy |
| Record Nr. | UNINA-9910595072903321 |
Vermehren Charlotte
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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EmbryoGenetics
| EmbryoGenetics |
| Autore | Simón Carlos |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (176 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
extracellular vesicles
exosomes microvesicles apoptotic bodies DNA preimplantation embryos murine blastocysts embryo uterus window of implantation PGT-A PGT-SR mosaicism embryo genetics chromosomal abnormality preimplantation genetic testing PGT-P polygenic risk scoring genomic index relative risk reduction combined preimplantation genetic testing Preimplantation genetic testing for monogenic disorders (PGT-M) Preimplantation genetic testing for aneuploidy assessment (PGT-A) Autosomal dominant polycystic kidney disease (ADPKD) male infertility advanced maternal age aneuploidy NGS segmental translocations monogenic disease multiplex PCR SNP array genome editing genetic diseases embryos vitrification ovarian response female age genetic testing reproductive health next-generation sequencing whole exome sequencing perinatal care infertility aneuploidies polygenic disease blastocyst endometrium implantation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557725303321 |
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Simón Carlos
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Extracellular Vesicles: Biology and Potentials in Cancer Therapeutics
| Extracellular Vesicles: Biology and Potentials in Cancer Therapeutics |
| Autore | Cho William |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (394 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
extracellular vesicle
precision oncology cancer biomarker prostate cancer drug delivery extracellular vesicles lysosome nanocarriers ultrasound size exclusion chromatography differential ultracentrifugation head and neck squamous cell carcinoma (HNSCC) exosomes cancer biomarker diagnostic therapy liquid biopsy small extracellular vesicles (sEV) tumor-derived exosomes (TEX) melanoma cell-derived exosomes (MTEX) proteomics tumor microenvironment biomarkers ectosomes neoplasia microvesicles small extracellular vesicles isolation purification size-exclusion chromatography ultracentrifugation sucrose density cushion lymph node spleen solid tissue microvesicle exosome cancer therapeutic drug carrier flow cytometry immunophenotyping swarm detection tumor-associated macrophages macrophage polarization mannose receptor HIV-1 Nef glioblastoma microRNA immunoprecipitation CD44 human milk nutrient microbiota microRNAs nanocommunicator diagnostic biomarker drug delivery vehicle personalized cancer immunotherapy therapeutic agents cell-to-cell communication ionising radiation non-targeted effects signalling imaging flow cytometry biomarker reservoirs cancer diagnostics disease monitoring large EVs ovarian cancer cells ES-2 OAW-42 adipose tissue origin mesenchymal stem cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Extracellular Vesicles |
| Record Nr. | UNINA-9910557555303321 |
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Cho William
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Basis and Gene Therapies of Cystic Fibrosis
| Molecular Basis and Gene Therapies of Cystic Fibrosis |
| Autore | Engelhardt John |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (210 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
cystic fibrosis
Staphylococcus aureus superantigen enterotoxin gene cluster MRSA exosomes microvesicles lung primary cells newborn screening trypsinogen CFTR gene next generation sequencing health policy rAAV2/HBoV1 baculovirus insect cells lung microbiome metagenomics gut–lung axis Cystic fibrosis CFTR transcriptomics proteostasis small molecules drug development common and new pathogenic variants ethnic Russian population gene therapy cyclophosphamide transient immunosuppression incidence survival genotype-phenotype correlations health policies CFTR modulators human nasal epithelial cells organoids biomarker functional assay pre-clinical in vitro models CFTR-related disorders molecular diagnosis CFTR variants Next Generation Sequencing (NGS) disease liability interpretation penetrance genotype-guided therapy miRNA airway basal cell lentivirus |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557392203321 |
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Engelhardt John
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Trends in Sport and Exercise Medicine
| New Trends in Sport and Exercise Medicine |
| Autore | Galli Daniela |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
rehabilitation
compliance anterior cruciate ligament reconstruction (ACLR) range of motion (ROM) self-efficacy behavioral design gamification microparticles microvesicles extracellular vesicles molecular markers cell-cell communication physical exercise physical activity angiogenesis secretome paracrine signaling cellular crosstalk ginseng performance recovery eccentric exercise inflammation allometry standing broad jump children growth maturity offset bench pull vertical jump power talent detection training insertional Achilles tendinopathy Achilles tendon moment arm suture bridge method cool-down strategy heart rate fatigue perception muscle strain quadriceps football invasive physiotherapy post-injury performance reinjury return to play autonomic nervous system cardiac autonomic regulation cardiorespiratory fitness daily training endurance secreted protein acidic and rich in cysteine (Sparc) exercise muscle performance metabolic phenotype lactate ageing high-impact weight-bearing exercise bone mineral density bone metabolic markers serum 25-(OH) D middle-aged premenopausal women ROS signal transduction aging air pollution lungs skeletal muscle mass muscular strength anaerobic power arterial stiffness cholinesterases heart rate variability autonomic recovery mechanisms sympathetic-parasympathetic modulation postexercise recovery ceramides cytokines diacylglycerol biomarkers |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557624503321 |
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Galli Daniela
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sample Preparation in Metabolomics
| Sample Preparation in Metabolomics |
| Autore | Kuligowski Julia |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (208 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
metabolomics
sample preparation hydrophilic interaction liquid chromatography ion mobility spectrometry high resolution mass spectrometry design of experiments AMOPLS metabonomics metabolic profiling NMR nuclear magnetic resonance spectroscopy cell line human cell line MiaPaCa-2 Panc-1 AsPC-1 extracellular vesicles exosomes microvesicles biomarkers diagnostics metabolic pathways plant metabolomics forestry trees mass spectrometry metabolite extraction GC-MS LC-MS metadata standardization databases multicellular tumor spheroids metallodrugs oxaliplatin KP1339 method development IT-139 20% FCS harvesting extraction metabolites normalization electromembrane extraction cardiovascular disease multi-segment injection capillary electrophoresis–mass spectrometry liquid chromatography–mass spectrometry plant natural products drug discovery liquid chromatography gas chromatography human milk metabolome sampling liquid chromatography–mass spectrometry (LC-MS) nuclear magnetic resonance (NMR) gas chromatography–mass spectrometry (GC-MS) capillary electrophoresis—mass spectrometry (CE-MS) high-resolution magic angle spinning microscopic samples lipidomics LC-MS/MS human plasma |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557141203321 |
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Kuligowski Julia
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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