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A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder
| A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder |
| Autore | Frye Richard E |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (416 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
acyl-carnitines
ADHD amygdala anxiety Array-Comparative Genomic Hybridization (Array-CGH) ASD associated risk autism autism spectrum disorder autism spectrum disorder (ASD) autism spectrum disorders autonomic disorder B12 biomarker brain brain development cerebral folate deficiency children chromosomal microarray analysis clinical decision support tool clinical utility cobalamin concomitant condition copy number variants cortisol COVID-19 cytokines digital biomarkers disorder Ehlers-Danlos syndrome energy metabolism epigenetics fatty acid oxidation fecal metabolites females fetal development Fisher Discriminant Analysis flavonoids folate receptor alpha folate receptor alpha autoantibodies folates folinic acid gastrointestinal symptoms genetic testing genomics glutathione heart rate variability hypermobility spectrum disorders immune dysfunction immunoglobulin G inflammation integrative intervention intravenous immunoglobulin leucovorin locked-in network syndrome logistic regression analysis luteolin mast cell activation syndrome mast cells medical claims metabolomics methylation methylcobalamin microbiome microglia minerals mitochondria model monoamine neurotransmitters n/a network connectivity neuromodulation neurostimulation neurotransmitter deficiency non-linear complex dynamics nutraceuticals OCD omics oxidative stress PANDAS parents patient stratification personalized treatment strategy polygenic risk scores precision medicine pregnancy prenatal environment proteomics quality of life redox metabolism resting-state functional magnetic resonance imaging resveratrol retrospective analysis SARS-CoV-2 single nucleotide polymorphisms sleep anxiety social dyads socio-motor parameters stochastic analysis stress survey systematic review Temple Grandin temporal lobe epilepsy time series analysis transcriptomics transdermal electrical neuromodulation vitamins wearables whole exome sequencing whole genome sequencing α-amylase |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595075503321 |
Frye Richard E
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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A Themed Issue in Honor of Professor Raphael Mechoulam: The Father of Cannabinoid and Endocannabinoid Research
| A Themed Issue in Honor of Professor Raphael Mechoulam: The Father of Cannabinoid and Endocannabinoid Research |
| Autore | Maccarrone Mauro |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (236 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research and information: general |
| Soggetto non controllato |
4'-fluoro-cannabidiol
6-hydroxydopamine alcohol craving allodynia aminoalkylindole amyotrophic lateral sclerosis anandamide anti-CB1 antibody anti-inflammatory antinociception biased signaling cannabichromene cannabidiolic acid cannabidivarin cannabidivarinic acid cannabigerol cannabinoid cannabinoid receptor cannabinoid receptor 2 (CB2R) cannabinoid tetrad cannabinoids catalepsy CB1 CB1 receptor antagonist cholesterol chromenopyrazole CP55940 drinking in the dark elevated plus maze endocannabinoid equilibrative nucleoside transporter frontal cortex functional selectivity G-protein ghrelin GPR55 receptors gut microbiome hippocampus HUF-101 hybrid ligand inflammaging iNOS inhibitor intestine intracerebroventricular administration JWH-018 K2 LEAP2 lipofuscin lipopolysaccharide marble bury memory microglia MRI-1867 mSOD1 mice N-acyltransferase n/a obesity Parkinson's disease phospholipase A2 phytocannabinoids PPARs pravadoline rescue model rimonabant spice synaptosomes TDP-43 transgenic mice tetrahydrocannabivarin two-bottle paradigm type 1 cannabinoid receptor CB1 VCE-006.1 WIN55212-2 β-arrestin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Themed Issue in Honor of Professor Raphael Mechoulam |
| Record Nr. | UNINA-9910566470103321 |
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Maccarrone Mauro
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Adipokines 2.0
| Adipokines 2.0 |
| Autore | Büchler Christa |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (406 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adipokine
adipokines adiponectin adipose tissue adipose-brain axis alpha-fetoprotein annexins biologic activity biomarker brain health C-C chemokine receptor-like 2 cancer Cardiovascular Diseases (CVDs) cathepsins chemerin chemerin receptors chemokine-like receptor 1 cholesterol complement factors critical illness depression early pregnancy early-life programming energy metabolism EP3 receptor EP4 receptor epicardial adipose tissue (EAT) excessive gestational weight gain exchange protein directly activated by cAMP isoform 2 (EPAC2) extracellular remodeling fat mass fatty liver fitness follicular fluid free fatty acids G protein-coupled receptor 1 gestational diabetes ghrelin glucose homeostasis glucose restriction human granulosa cells hypertension hypothalamus ICU in vitro fat regain inflammation insulin interleukin(IL)-33 label-free proteomic profiling leptin leukocyte lipid metabolism lipids liver steatosis metabolically healthy obese microglia myokine n/a neonatal anthropometry neurodegeneration Nonalcoholic fatty liver disease obesity oestrous cycle osteoarthritis ovary PCOS pig polycystic ovary morphology polycystic ovary syndrome preeclempsia prognosis prostaglandin E2 (PGE2) proteolysis resistin rheumatic diseases rheumatoid arthritis secreted frizzled-related protein 5 sepsis SGBS adipocytes sick fat stimulating growth factor 2 (ST2) Tango bioassay testicular pathologies testis tocilizumab triglycerides visceral fat weight regain |
| ISBN | 3-03928-587-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404092003321 |
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Büchler Christa
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Multiple Sclerosis Research-Series I
| Advances in Multiple Sclerosis Research-Series I |
| Autore | Matsoukas John |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (334 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adult-onset
agonist peptide alemtuzumab altered peptide ligands antibodies against GluR3 peptide antibody detection antigen-specific immunotherapies antigen-specific immunotherapy astrocytes autoimmune diseases autoimmune encephalitis autoimmunity B cell receptor biomarker bupropion carriers cellular immunity central nervous system cerebral blood flow chloroquine clinical outcome clinical outcomes clinical phenotype cognitive impairment conformational analysis conjugation cranial nerve-VI palsy craniopharyngioma delivery methods dendritic cells diagnosis diagnostic markers disease-modifying treatments drug delivery nanosystems EAE early-onset ELISA experimental autoimmune encephalomyelitis fampridine fractionated stereotactic radiation treatments free light chains Graphite/SiO2 electrode gut microbiome gut-brain axis HPLC Human Leucocyte Antigens immune modulation immune thrombocytopenic purpura immunogenetics immunoglobulins immunomodulation immunotherapeutics immunotherapy inflammation intracortical facilitation kappa lipids major depression mannan MBP83-99 peptide memory T cells metagenomics microglia MOG35-55 molecular dynamic monoclonal antibodies MS MS drugs multiple sclerosis Multiple Sclerosis multivalency myelin basic protei myelin oligodendrocyte glycoprotein myelin peptides N-glucosylated peptide epitopes nanoparticles nanotechnology neurodegeneration neuroimaging neuropsychological assessment NMR spectroscopy NOE-constraints oligodendrocytes oxidative peptide peptides plasma exchange polymers positron emission tomography probiotics proteolipid protein S-adenosylmethionine sample size short intracortical inhibition sphenoid sinusitis ST285 Streptococcus thermophilus T cell receptor tDCS tetraspanins therapeutics tolerance tolerance induction tolerogenic vaccines trimolecular complex TSPAN32 vaccine vaccines vitamin D3 voltammetry walking disability yoga |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557385403321 |
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Matsoukas John
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Botulinum Neurotoxins and Nervous System : Future Challenges for Novel Indications
| Botulinum Neurotoxins and Nervous System : Future Challenges for Novel Indications |
| Autore | Luvisetto Siro |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (368 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
abobotulinumtoxinA
allodynia antipruritic appropriate treatment astroglia basal ganglia biological effect BoNT/A botulinum antitoxin botulinum neurotoxin botulinum neurotoxin serotype A botulinum neurotoxin serotype a heavy chain (BoNT/A HC) botulinum neurotoxin-A botulinum neurotoxins botulinum toxin Botulinum toxin botulinum toxin A botulinum toxin therapy botulinum toxin type A BTX central neuropathic pain cerebral palsy chloroquine chronic pelvic pain clinical clinical decision support clinical trial Clostridium tetani complex regional pain syndrome compound 48/80 delivery dental occlusion dermatology diagnostic guidance drooling dystonic tremor early use eccrine glands electrical activity electrical stimulation electromyography epilepsy essential tremor experimental food safety formulation glia growth associated protein 43 (GAP-43) hand hand tremor heavy chain human immunohistochemistry incobotulinumtoxin A interleukins interneurons interspecies differences in motor behavior itch joint biomechanics kinematics lateral pterygoid muscle limb tremors lumbar sympathetic ganglion block mast cells masticatory system maxillofacial bone medication overuse headache microglia mouse mouse test movement disorders muscle selection n/a nerve regeneration neural regeneration neuronal processes neurotransmission blockade neurotransmitter new indications novel indication onabotulinumtoxin A ONTIME orthognathic surgery overactive detrusor pain Parkinson's disease post-stroke post-stroke shoulder pain prion disease prophylactic treatment pruritus rat refractory chronic migraine rehabilitation salivary glands Schwann cells sciatic static index sialorrhoea Snap-23 SNAP-25 SNARE spastic paresis spasticity spinal cord spinal cord injury spinal cord injury (SCI) stroke management superior cervical ganglion 10 (SCG10) swallowing synaptic transmission temporomandibular joint dislocation tension headache Therapeutic Index TLR2 TLR4 treatment tremor upper limb biomechanics upper limb spasticity urodynamics vaginism VAMP various cell types walking track analysis weight bearing XEOMIN® |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Botulinum Neurotoxins and Nervous System |
| Record Nr. | UNINA-9910557109003321 |
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Luvisetto Siro
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach
| Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2023 |
| Descrizione fisica | 1 online resource (428 p.) |
| Soggetto topico |
Medicine and Nursing
Neurology and clinical neurophysiology |
| Soggetto non controllato |
18F-FDG PET
AGTPBP1 Alzheimer's disease amyloid beta anosmia anti-convulsants anti-epileptic drugs apoptosis blunt-force TBI brain injury CCP1 chronic alcoholism cognitive impairment CONDCA COVID-19 drug targets edema epigenetics epileptogenesis excitotoxicity exomiRNA exosome extracellular matrix FABP3 FABP5 FABP7 gene regulation GSK-3β HHV-6 histone deacetylase histone deacetylase inhibitor hypoxia hypoxic-ischemic injuries icariin icaritin inflammation ischemia ischemic stroke isomiR mechanical stimulations microglia microRNA middle cerebral artery occlusion mild traumatic brain injury miRNA mitochondria moderate traumatic brain injury mPGES-1 n/a natural products neural ischemia neural mitochondrial functions neural tissue hypoxic injuries neuraxis neuro-recovery neurodegeneration neurodegenerative diseases neuroinflammation neurons neuroprotection neurorehabilitation neurotrauma NNA1 non-communicable disease olfactory dysfunction organelle dysfunction oxidative stress p-Tau Parkinson's disease pcd PGE2 phytochemicals post-traumatic seizures pseudo-resistance purmorphamine reactive oxygen species RNAseq SARS-CoV-2 seizures sonic hedgehog signaling stretching Substantia Nigra TBI therapeutic strategies transcriptional modifications traumatic brain injury traumatic brain injury (TBI) treadmill exercise tRNA zebrafish |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Brain Injury and Neurodegeneration |
| Record Nr. | UNINA-9910743275703321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular and Molecular Mechanisms in Pathogenesis of Multiple Sclerosis
| Cellular and Molecular Mechanisms in Pathogenesis of Multiple Sclerosis |
| Autore | Wan Edwin |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (182 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
A971432
autoimmune disease AUY954 bioinformatics CD4+ T cells central memory T cell clonal analyses demyelination disease activity effector memory T cell experimental autoimmune encephalomyelitis experimental autoimmune encephalomyelitis (EAE) gliosis glutamate synaptic dysfunction granulocyte-macrophage colony-stimulating factor histology IDO in utero electroporation inside-out kynurenic acid kynurenine pathway laquinimod lesioned brain lineage lymphocytes memory T cells microglia mitochondria monocytes morphometric analyses multiple sclerosis N-acetylserotonin n/a NAD+, multiple sclerosis neuroinflammation neutrophils NG2-glia NLR oligodendrocytosis outside-in oxidative stress ozanimod pentamidine pro-inflammatory cytokines progenitors quinolinic acid relapsing-remitting experimental autoimmune encephalomyelitis S100B S1P1 S1P5 sphingosine-1-phosphate receptors T lymphocytes tissue-resident T cell top-down proteomics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557306103321 |
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Wan Edwin
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Developmental Exposure to Environmental Contaminants
| Developmental Exposure to Environmental Contaminants |
| Autore | Stietz Kimberly Keil |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (256 p.) |
| Soggetto topico |
Medicine
Medical toxicology |
| Soggetto non controllato |
arsenic
synaptic transmission long-term potentiation hippocampus development lower urinary tract bladder inflammation POPs developmental basis of adult disease multigenerational toxicants bronchopulmonary dysplasia therapeutics lung development selective serotonin reuptake inhibitor perinatal mortality neonatal morbidity fluoxetine sertraline endocrine-disrupting chemicals (EDC) Aroclor 1221 (A1221) PCBs vinclozolin social behavior sex differences transgenerational epigenetic endocrine-disrupting chemical (EDC) polychlorinated biphenyl (PCB) mating behavior paced mating ultrasonic vocalization (USV) estradiol triclosan triclocarbon detergents 4-nonylphenol Danio rerio zebrafish environmental toxicity aquatic environment ground water chemicals lower urinary tract dysfunction lower urinary tract symptoms BPH prostate axonal growth developmental neurotoxicity neuronal morphogenesis PBDE reactive oxygen species thyroid hormone pesticides prebiotic intestinal dysbiosis perigestational dysmetabolism risk factor behavior chemical screening literature comparison developmental toxicity negative control positive control rapid testing PFAS PFAS mixtures epigenetics microglia valproic acid primary motor cortex |
| ISBN | 3-0365-5885-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639989003321 |
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Stietz Kimberly Keil
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dual role of Microglia in Health and Disease: Pushing the Balance Towards Repair
| Dual role of Microglia in Health and Disease: Pushing the Balance Towards Repair |
| Autore | Ferreira Raquel |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (176 p.) |
| Soggetto topico |
Neurosciences
Science: general issues |
| Soggetto non controllato |
cytokines
intercellular communication microglia neurodegenerative diseases neuroinflammation phagocytosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Dual role of Microglia in Health and Disease |
| Record Nr. | UNINA-9910557564803321 |
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Ferreira Raquel
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Flavonoids and Their Disease Prevention and Treatment Potential
| Flavonoids and Their Disease Prevention and Treatment Potential |
| Autore | Rupasinghe H.P. Vasantha |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (346 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
A-type proanthocyanidins
Acer okamotoanum afzelin aglycons allodynia amoebiasis analgesia angiogenesis anthocyanin anti-aging activity antiadhesive activity anticancer activity antioxidant activity antiprotozoal agents apigenin apoptosis aspirin bacopaside I bacoside A bacterial sepsis bioguided isolation black rice cyanidin-3-O-glucoside CAM assay cancer cancer chemoprevention cancer prevention cancer stem cells canine cancer cell lines carcinogenesis CD44+/CD24− CDKs cell cycle cell morphology cell proliferation chalcones chronological lifespan citrus citrus flavonoids clinical trials cognition colorectal cancer COVID-19 cranberry CVD cytokines defatted pitaya seed DNA damage dyslipidemia extraction flavan-3-ols flavones flavonoid flavonoid content flavonoids flavonoids and their derivatives foods for health gene and protein regulatory networks glycosides human colon cancer cells hydroxybenzoic acids hyperalgesia hypersensitivity IKKβ, inflammatory cytokines IL-1β IL-6 IL-8 in-vivo angiogenesis infectious diseases inflammation isoquercitrin isorhamnetin lung cancer luteolin macrophages membrane PUFAs profile memory extinction Mexican oregano mice microbiome microglia molecular mechanisms n/a natural products neohesperidin neuroprotection NF-kB NF-κB non-flavonoids obesity passive avoidance test phenolic content phenolic metabolites phytochemicals phytomedicine pro-inflammatory cytokines probiotics quercitrin response surface methodology SAR SARS-COV-2 smart nanoparticles Stat3 synergistic effect tangeretin TNF-α tobacco-specific nitrosamine toll-like receptor 4 UPEC urinary tract infections uropathogenic Escherichia coli UTIs vasorelaxation wood sterols |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557505903321 |
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Rupasinghe H.P. Vasantha
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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