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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (528 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
melanoma
invasion WNT5A MARCKS phosphorylation MANS peptide nanoparticles cell therapy tumor microenvironment sex/gender sex-hormones immunity microRNAs immunotherapy BRAF-mutant melanoma BRAF inhibitor mechanism of action targeted therapy tumour microenvironment plasmacytoid dendritic cells lactate dehydrogenase TLR interferon CXCL10 TPC2 HIPPO SOCE metastasis essential oils angiogenesis apoptosis uveal melanoma (UM) metastatic uveal melanoma (mUM) prognostication adjuvant therapy metastatic therapy metastatic dormancy liver-directed-therapies targeted-therapy combined therapy protein tyrosine phosphatase PTPs inhibitors melanoma immune infiltrate BRAF inhibitors microenvironment resistance therapy therapeutic resistance exosomes extracellular vesicles diagnosis prognosis ctDNA liquid biopsy prediction patient stratification BRAF arthralgia rheumatoid arthritis carbonic anhydrase hedgehog cyclopamine small molecules acetazolamide motility metalloproteinases FAK cancer mucosal melanoma nivolumab pembrolizumab ipilimumab radiotherapy cholinergic system acetylcholine muscarinic receptors nicotinic receptors melanoma metastasis ShcD adaptor protein amoeboid motility Rac1 DOCK4 melanoma PDX target therapy cancer stem cells slow cycling phenotype drug resistance OXPHOS lipid metabolism cancer associated fibroblast melanomagenesis biomarkers checkpoint inhibitor PD-1 melanoma markers cytokines machine learning Support Vector Machine principal component analysis BCL2L10 STAT3 cytotoxicity survival ABT-737 Bcl-2 family ML258 HuR MITF metastases siRNA |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Aging and Age-related Disorders: From Molecular Mechanisms to Therapies
| Aging and Age-related Disorders: From Molecular Mechanisms to Therapies |
| Autore | Titorenko Vladimir |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (322 p.) |
| Soggetto non controllato |
advanced glycated end products
microRNAs differentiation transcription skin absorption cellular quiescence lifespan longevity genes protein kinases self-renewal circadian blood-brain barrier aging-related disorders sirtuin-1 inflammation arterial aging reactive oxygen species electron microscopy reconstructed human skin rejuvenation low-dose fluvastatin and valsartan combination inflammaging hematopoietic stem cell aging cell cycle mitochondria ribose the nervous system nanomedicine proteostasis adult stem cells immunosenescence cell signaling mechanisms of quiescence maintenance metabolism aging melatonin diabetes mechanisms of quiescence entry and exit Drosophila melanogaster GSK3 (glycogen synthase kinase 3) |
| ISBN | 3-03921-356-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Aging and Age-related Disorders |
| Record Nr. | UNINA-9910367567903321 |
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Titorenko Vladimir
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cadmium Sources and Toxicity
| Cadmium Sources and Toxicity |
| Autore | Satarug Soisungwan |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (130 p.) |
| Soggetto non controllato |
microRNAs
embryonic kidneys exposure assessment image analysis periodontal disease menopause nephrotoxicity urine protein mitochondrial morphology female alveolar bone population health glomerular filtration rate threshold limit biomarkers toxicity threshold limit osteotoxicity intrauterine exposure metabolic syndrome dietary cadmium periodontitis cadmium toxicity metabolic disruptor cadmium urine cadmium chronic kidney disease N-acetyl-?-d-glucosaminidase estimated glomerular filtration rate one health clinical kidney function measure ?2-microglobulin cause of death follow-up study menarche HIF-1 bioenergetics sub-lethal exposure metformin toxicological mechanism tubular dysfunction mitochondrial network environmental pollution mortality body burden indicator cancer hypertension |
| ISBN | 3-03897-985-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346850303321 |
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Satarug Soisungwan
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cell Biology of Galectins
| Cell Biology of Galectins |
| Autore | Timoshenko Alexander |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
galectin-7
p53 MMP-9 cancer gain-of-function vasculature gene expression tube formation sprouting VEGF integrins galectin extracellular matrix microenvironment Yersinia enterocolitica YopP Galectin-1 nitric oxide macrophages epithelial tissues apoptosis targeting inhibitors β-hairpin β-sandwich blood group B lectin sugar code LGALS16 placenta brain tissues cell differentiation transcription factor miRNA galectin-3 cardiac fibrosis heart failure atrial fibrillation chronic inflammation MMPs microRNAs lncRNAs pectin structure and function bioactive polysaccharides galectin-3 inhibition galacto-oligosaccharides galectins intestinal epithelial cells β-3'galactosyllactose immunomodulation mucosal immunity O-GlcNAc unconventional secretion extraembryonic endoderm |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580216003321 |
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Timoshenko Alexander
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cell Signaling in Model Plants
| Cell Signaling in Model Plants |
| Autore | Chen Jen-Tsung |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (278 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
salinity
selenium (Se) crops reactive oxygen species (ROS) enzymatic anti-oxidative system drought GA DELLA ABF2 protein-protein interaction Arabidopsis endocytosis microRNAs miPEPs peptides development kinase receptor stress tobacco calcium calcite reactive oxygen species ion channels cellular signalization brassinosteroids receptor-like kinases GSK3-like kinases somatic embryogenesis receptor-like kinases protein phosphatases Malus domestica Rosaceae juvenility FLOWERING LOCUS C flowering Hydrogen sulfide S-sulfhydration plant hormone gasotransmitter disease resistance plant defense herbivore phytohormone plant biotic stress plant signalling Medicago truncatula abiotic stress cAMP cyclic nucleotides-gated channels plant innate immunity Botrytis cinerea tomato iprodione mutant transcriptome analysis metabolism catalytic activity dwarfism gene cloning MNP1 CPS ABA signaling brassinosteroid signaling cascade drought tolerance priming stress adaptation stress memory CRISPR/Cas9 DELLA/TVHYNP Dwarf GA20OX2 GA signaling |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557518203321 |
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Chen Jen-Tsung
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Colorectal Cancers: From Present Problems to Future Solutions
| Colorectal Cancers: From Present Problems to Future Solutions |
| Autore | Allgayer Heike |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
Phage
bacteriophages diet infection colorectal cancer nutrition circulating tumor cells colorectal cancer EPISPOT assay CellSearch® system predictive value chromatin density nanoscale tumour cell heterogeneity microRNAs metastasis super-resolution microscopy early onset cohort epidemiology liquid biopsy biomarker indirect carcinogenesis bovine meat and milk factors (BMMF) chronic zoonosis multiplex tumor immunology immune landscape spontaneous feline intestinal tumors comparative oncology tumor budding CTNNB1 genome-wide methylation array methylation miRNA colon cancer personalized treatment drug combinations Matrix Metalloproteinases (MMPs) polyp TIMPs MMP polymorphisms MMP targeting S100A4 DKK1 Wnt signaling patient survival gender rectal cancer radiochemotherapy radiosensitivity DNA double-strand breaks deposited energy quality of life blood values (molecular) carcinogenesis cancer progression (single) cancer cell heterogeneity models infectious agents (targeted) therapy personalized medicine |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Colorectal Cancers |
| Record Nr. | UNINA-9910585937103321 |
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Allgayer Heike
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology
| Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology |
| Autore | Fioravanti Antonella |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (320 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
miR-27a-5p
acute myocardial infarction autophagy apoptosis hypoxia MicroRNA (miRNA) miR526b miR655 oxidative stress reactive oxygen species (ROS) superoxide (SO) Thioredoxin Reductase 1 (TXNRD1) breast cancer nucleic acid medicine pancreatic cancer clinical trial siRNA antisense oligonucleotide MicroRNA signal transduction therapeutic target miRNAs ROS noncoding RNA microRNA long noncoding RNA mitochondrial dysfunction nitrosative stress. exosome cross-talk systemic lupus erythematosus visfatin resistin osteoarthritis synovial fibroblasts synovitis NF-κB thyroid hormone liver cancer metabolism physiology ASH NAFLD NASH HCC HCV HBV endometriosis high-grade serous ovarian cancer endometriosis-associated ovarian cancer epithelial-to-mesenchymal transition chemoresistance antioxidants miRNA cancer diabetes beta cells microRNAs translation regulation neurodegeneration Alzheimer's disease Parkinson's disease Huntington's disease ALS reactive oxygen species redox signaling therapeutic tolerance therapeutic resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557526003321 |
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Fioravanti Antonella
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Current Advances on Non-Melanoma Skin Cancer
| Current Advances on Non-Melanoma Skin Cancer |
| Autore | Caruntu Constantin |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (124 p.) |
| Soggetto topico |
Research & information: general
Technology: general issues |
| Soggetto non controllato |
basal cell carcinoma
diagnostic test accuracy in vivo reflectance confocal microscopy systematic review meta-analysis photochemotherapy methylaminolevulinate actinic keratosis vitamin d calcitriol vitamin d receptor skin cancer diagnosis cytology actinic cheilitis squamous cell carcinoma lip neoplasms cutaneous squamous cell carcinoma ultraviolet radiation genes microRNAs lncRNAs novel therapeutic approaches non-melanoma skin cancer Merkel cell carcinoma telomeres telomerase epigenetics miRNA Hedgehog pathway signaling pathways carcinogenesis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557361703321 |
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Caruntu Constantin
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Extracellular Vesicles: Biology and Potentials in Cancer Therapeutics
| Extracellular Vesicles: Biology and Potentials in Cancer Therapeutics |
| Autore | Cho William |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (394 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
extracellular vesicle
precision oncology cancer biomarker prostate cancer drug delivery extracellular vesicles lysosome nanocarriers ultrasound size exclusion chromatography differential ultracentrifugation head and neck squamous cell carcinoma (HNSCC) exosomes cancer biomarker diagnostic therapy liquid biopsy small extracellular vesicles (sEV) tumor-derived exosomes (TEX) melanoma cell-derived exosomes (MTEX) proteomics tumor microenvironment biomarkers ectosomes neoplasia microvesicles small extracellular vesicles isolation purification size-exclusion chromatography ultracentrifugation sucrose density cushion lymph node spleen solid tissue microvesicle exosome cancer therapeutic drug carrier flow cytometry immunophenotyping swarm detection tumor-associated macrophages macrophage polarization mannose receptor HIV-1 Nef glioblastoma microRNA immunoprecipitation CD44 human milk nutrient microbiota microRNAs nanocommunicator diagnostic biomarker drug delivery vehicle personalized cancer immunotherapy therapeutic agents cell-to-cell communication ionising radiation non-targeted effects signalling imaging flow cytometry biomarker reservoirs cancer diagnostics disease monitoring large EVs ovarian cancer cells ES-2 OAW-42 adipose tissue origin mesenchymal stem cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Extracellular Vesicles |
| Record Nr. | UNINA-9910557555303321 |
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Cho William
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Hereditary Hemorrhagic Telangiectasia : Recent Advances and Future Challenges
| Hereditary Hemorrhagic Telangiectasia : Recent Advances and Future Challenges |
| Autore | Mager Hans-Jurgen |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (228 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
hereditary hemorrhagic telangiectasia
rare diseases telangiectasis transforming growth factor-beta (TGF-β) Smad pathway gastrointestinal bleeding epistaxis nosebleeds tacrolimus nasal ointment genetic disease rare disease hereditary hemorrhagic telangiectasia (HHT) telangiectases mechanical damage sun-induced trauma vascular malformations Endoglin activin-receptor-like kinase 1 Hereditary Hemorrhagic Telangiectasia antithrombotic therapy anticoagulants antiplatelets bleeding safety HHT ALK1 endoglin raloxifene bazedoxifene tranexamic acid propranolol FK506 etamsylate N-acetylcysteine pulmonary arteriovenous malformations transcatheter embolotherapy screening guidelines Hereditary hemorrhagic telangiectasia pediatrics genotype–phenotype correlation arteriovenous malformation ENG ACVRL1 SMAD4 microRNA biomarker plasma arteriovenous malformations (AVMs) angiogenesis activin receptor-like kinase 1 (ALK1) transforming growth factor beta (TGF-β) bone morphogenetic protein (BMP) propranolol gel epistaxis severity score nasal endoscopy antiangiogenic properties non-coding RNAs microRNAs long non-coding RNAs biomarkers endothelial cells hereditary hemorrhagic telangiectasia (HHT), second-hit arteriovenous malformation (AVM) Smad4 inflammation shear stress vascular injury somatic mutation cell adhesion vascular endothelial growth factor (VEGF) telangiectasia hereditary hemorrhagic survival life expectancy pulmonary arteriovenous malformation contrast enhanced magnetic resonance angiography liver MRI ultrasound AVM bevacizumab Osler–Weber–Rendu hereditary hemorrhagic telangiectasia/HHT/osler’s disease cerebral ischemic lesions catheter based embolization therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Hereditary Hemorrhagic Telangiectasia |
| Record Nr. | UNINA-9910557578003321 |
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Mager Hans-Jurgen
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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