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Animal Modeling in Cancer
| Animal Modeling in Cancer |
| Autore | Korinek Vladimir |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (273 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
soy
isoflavones mammary tumor prevention rodent models chemical carcinogens transgenic mice Zebrafish Drosophila rats mice NPM-1 FLT3 ITD ETO-1 IDH1/2 neural stem cells brain and nervous system cancers neurogenic niches radiotherapy sparing of neurogenic regions carcinoma consensus molecular subtypes intestine oncogenes signaling cascades tumor suppressors tumorigenesis MPN (myeloproliferative neoplasms) zebrafish iPSCs JAK2 MPL CALR thrombosis ubiquitin–proteasome system cancer mouse model gene inactivation colorectal cancer mouse models microbiota antitumor immunity melanoma mutation genetics animal model swine MeLiM progression spontaneous regression devitalization metaplasia Cdx animal models epigenetics xenotransplantation drug screen pre-clinical cancer model non-mouse models gene editing stem cells solid tumors hematologic malignancies |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557344403321 |
Korinek Vladimir
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological Efficacy of Natural and Chemically Modified Products against Oral Inflammatory Lesions
| Biological Efficacy of Natural and Chemically Modified Products against Oral Inflammatory Lesions |
| Autore | Sakagami Hiroshi |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (212 p.) |
| Soggetto non controllato |
gargle
oral lichen planus angiotensin II blocker quantitative structure-activity relationship metabolomics CCN2 anti-human immunodeficiency virus (HIV) oral cell arachidonic acid cascade Kampo medicine lignin-carbohydrate complex traditional medicine eugenol QSAR analysis constituent plant extract polyphenol benzaldehyde glucosyltransferase infective endocarditis antiviral periodontitis nutritionally variant streptococci Kampo quantitative structure-activity relationship (QSAR) analysis traditional Japanese herbal medicine technical terms allergic rhinitis nasal epithelial cell antimicrobial susceptibilities alkaline extract mastic stomatitis thioredoxin production oral microbiota Jixueteng oral inflammation random forest mice chromone natural products Chinese herbal remedies inflammation quercetin in vivo kampo formula glucocorticoids Hangeshashinto recurrent aphthous stomatitis anti-osteoclast activity cytotoxicity dental application tongue diagnosis natural product alkaloids inflammatory disease pathogenic factors increase machine learning human virus cepharanthin mucositis oral diseases Juzentaihoto in vitro herbal medicine tumour-specificity |
| ISBN | 3-03897-993-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346850803321 |
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Sakagami Hiroshi
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular and Molecular Mechanisms of Nephropathic Cystinosis
| Cellular and Molecular Mechanisms of Nephropathic Cystinosis |
| Autore | Levtchenko Elena N |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (230 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
cystinosis
cysteamine bone osteoclast genotype CD34+ hematopoietic stem and progenitor cells gene therapy pre-clinical studies investigational new drug application clinical trial disulfiram mice zebrafish fertility azoospermia hypogonadism histopathology mouse model lysosomal storage disease cell and animal models infantile nephropathic cystinosis bone-muscle wasting fibroblast growth factor 23 osteoclasts sclerostin leptin fractures nephropathic cystinosis hollow fiber membrane 3-dimensional models autophagy macrophages inflammasome proximal tubular cells endocytosis apoptosis chitotriosidase interleukins galectin-3 novel therapies endolysosome epithelial cell differentiation homeostasis lysosomal storage diseases mitochondrial distress kidney proximal tubule programmed cell death central nervous system cortical atrophy arterial spin labelling cystine blood level lysosomal storage disorder history treatment strategies for cystinosis newborn screening clinical course CTNS-pathogenic variants newborn screening for cystinosis kidney progenitors cell model biomarkers cystine kidney therapeutic monitoring |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585941103321 |
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Levtchenko Elena N
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Current Insights on Lipid-Based Nanosystems
| Current Insights on Lipid-Based Nanosystems |
| Autore | Silva Ana Catarina |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
Echinococcus granulosus
scolicidal nanoliposome juglone apoptotic activity hydrogel SLNs nose-to-brain delivery mucoadhesion quality by design antioxidant activity nasal administration nanostructured lipid carriers solid lipid nanoparticles in vitro cell cultures 3D nasal casts lung cancer targeted drug delivery lipid-based nanocarriers pulmonary delivery dry powder inhalers aerosols liposomes nanoemulsions nanotechnology biologically active compounds dermal drug delivery polyphenols phytophenols skin permeation chemotherapy radiotherapy active targeting passive targeting tumor immunoconjugate traditional liposome stealth liposome triggered release limitations of liposomes drug transfer in vitro release colloidal drug carriers lipid nanoparticles hydrogel beads cholesteryl nonanoate bovine serum albumin skin diseases lipid-based nanosystems cream ointment gel pH-sensitive liposome imidazole anticancer drug delivery multicellular spheroids dapagliflozin Box-Behnken design FTIR DSC XRD SEM AFM in vitro Franz diffusion cells lipid-based nanoparticles nanocarrier surface charge delivery systems chronic treatment mice anti-oxidant activity hepatoprotective effect phospholipid phytosomes Silymarin Colorectal Cancer Niosomes Oxaliplatin Paclitaxel d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) therapeutic nucleic acids schizophrenia quetiapine fumarate glycerosomes central composite rotatable design bioavailability pharmacokinetic |
| ISBN | 3-0365-6165-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639995103321 |
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Silva Ana Catarina
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Emerging and Re-Emerging Diseases-Novel Challenges in Today's World
| Emerging and Re-Emerging Diseases-Novel Challenges in Today's World |
| Autore | Mesquita João R |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (151 p.) |
| Soggetto topico |
Medicine
Epidemiology & medical statistics |
| Soggetto non controllato |
trefoil factor family member 2 (TFF2)
inflammation tissue repair zoonotic disease Panthera leo human health biosecurity wildlife farming wildlife trade disease transmission BRSV cattle isolation respiratory disorders sequencing avian influenza homologous vaccine heterologous vaccine broiler early infection bovine papillomavirus Egypt nucleic acid lateral flow immunoassay PCR phylodynamic whole-genome sequencing (WGS) chicken antimicrobial resistance genes virulence genetic cluster schistosome Allobilharzia visceralis whooper swans obstructive phlebitis endosymbionts Hemolivia surveillance tortoises tick-borne pathogens ticks haemogregarines gamogony sporogony schizongony molecular analysis high-fat diet immunity damage mice Brazil HEV zoonotic One Health |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557666703321 |
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Mesquita João R
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Flavonoids and Their Disease Prevention and Treatment Potential
| Flavonoids and Their Disease Prevention and Treatment Potential |
| Autore | Rupasinghe H.P. Vasantha |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (346 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
luteolin
apigenin bacoside A bacopaside I vasorelaxation isorhamnetin flavonoid bacterial sepsis toll-like receptor 4 inflammation citrus flavonoids neohesperidin anti-aging activity chronological lifespan synergistic effect clinical trials natural products hyperalgesia allodynia analgesia hypersensitivity cytokines NF-kB defatted pitaya seed extraction phenolic content flavonoid content antioxidant activity response surface methodology flavonoids aglycons glycosides IL-1β TNF-α IL-6 IL-8 pro-inflammatory cytokines Acer okamotoanum afzelin isoquercitrin obesity quercitrin aspirin cancer prevention hydroxybenzoic acids cell cycle CDKs colorectal cancer infectious diseases amoebiasis Mexican oregano bioguided isolation antiprotozoal agents flavones cancer microbiome molecular mechanisms gene and protein regulatory networks macrophages NF-κB IKKβ, inflammatory cytokines apoptosis foods for health tangeretin cancer stem cells Stat3 citrus CD44+/CD24− phytochemicals flavonoids and their derivatives phytomedicine COVID-19 SARS-COV-2 smart nanoparticles non-flavonoids membrane PUFAs profile cell morphology human colon cancer cells cranberry urinary tract infections UTIs uropathogenic Escherichia coli UPEC flavan-3-ols A-type proanthocyanidins phenolic metabolites antiadhesive activity probiotics anthocyanin tobacco-specific nitrosamine carcinogenesis cell proliferation cancer chemoprevention lung cancer chalcones DNA damage anticancer activity canine cancer cell lines angiogenesis in-vivo angiogenesis CAM assay SAR cognition passive avoidance test memory extinction mice microglia neuroprotection black rice cyanidin-3-O-glucoside wood sterols dyslipidemia CVD |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557505903321 |
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Rupasinghe H.P. Vasantha
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Identification and Characterization of Genetic Components in Autism Spectrum Disorders 2019
| Identification and Characterization of Genetic Components in Autism Spectrum Disorders 2019 |
| Autore | Butler Merlin G |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (256 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Genetics (non-medical) |
| Soggetto non controllato |
autism spectrum disorders (ASD)
cancer overlapping genes and gene profiling super-pathways phenotypes and diseases molecular functions and processes 15q11.2 BP1-BP2 microdeletion (Burnside-Butler) syndrome imprinting parent-of-origin effects phenotype-genotype correlation autism developmental delays motor delays microbiome gut ProSAP2 Phelan McDermid Syndrome gut–brain interaction leaky gut IL-6 SHANK collapsin response mediator protein 4 autism spectrum disorder neurodevelopmental disorder whole-exome sequencing animal model sex different phenotypes 15q11.2 BP1–BP2 microdeletion (Burnside–Butler syndrome) NIPA1 NIPA2 CYFIP1 TUBGCP5 genes Prader–Willi and Angelman syndromes magnesium transporters and supplementation potential treatment options intellectual disability AMPA receptors NMDA receptors guanine nucleotide exchange factor synaptic plasticity Autism spectrum disorder ASD Obesity Overweight Body mass index BMI autism candidate genes synaptotagmin-like protein 4 (SYTL4) transmembrane protein 187 (TMEM187) SYTL4-protein structure STRING-protein-protein interaction expression profile microRNA- interactions autism spectrum disorders biological networks genomics multi-omics network diffusion data integration genetics quantitative traits stratification by trait severity heterogeneity reduction case-control association analysis fragile X syndrome RNA toxicity DNA methylation mosaicism pediatrics MS-QMA AmplideX cytokine monocyte β-glucan T cell cytokine trained immunity maternal immune activation epigenetics mice postnatal VPA injection SAM gene expression nanostring |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566483203321 |
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Butler Merlin G
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Medicinal Plants and Foods
| Medicinal Plants and Foods |
| Autore | Nieto Gema |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (165 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
anti-obesity
anti-lipase traditional medicine folkloric food Acetaminophen Vernonia calvoana serum lipid indices hypolipidemic activity and antioxidants flavonoids diabetes Rosaceae Mespilus germanica mice brine-injected pork green tea extract maté extract ascorbate protein oxidation sensory quality high-oxygen modified atmosphere packaging brine injection pork lipid oxidation modified atmosphere packaging hydroxytyrosol antioxidant antimicrobial meat preservative health antioxidants Lamiaceae polyphenols Stachys mucronata Capnophyllum peregrinum antioxidant activity photoprotective activity macroalgae microalgae extraction yield total phenolic content Euphorbia dendroides phenolic compounds HPLC antiproliferative activity Caco-2 cells iron bioavailability phytic acid agro by-products food waste waste utilization anti-inflammatory medicinal plants chronic diseases Uncaria tomentosa Harpagophytum procumbens Myrciaria dubia Ribes nigrum hesperidin rosemary |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557798603321 |
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Nieto Gema
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Modulators of Oxidative Stress : Chemical and Pharmacological Aspects
| Modulators of Oxidative Stress : Chemical and Pharmacological Aspects |
| Autore | Saso Luciano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (298 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
ascorbic acid
deferoxamine N-acetylcysteine ischemia/reperfusion cardiac fibroblasts reactive oxygen species photobiomodulation reactive oxygen species (ROS) nuclear factor kappa-light-chain-enhancer of activated B cells (NF-кB) cancer diabetes wound healing glucose pentose phosphate pathway NADPH redox balance glycogen glycolysis stress resistance insulin resistance immunomodulation inflammation olive tree oxidative stress secoirioids sirtuin 3 high fat diet sex differences mice metabolic stress antioxidants ADHD Nrf2 NRF2-KEAP1 ROS cancer metabolism antioxidant cancer therapy chemoresistance radioresistance sepsis MitoVitE mitochondria gene expression cytokines mRNA vitamin C folic acid one-carbon metabolism C2C12 cells metabolomics mass spectrometry type 2 diabetes dipeptidyl peptidase-4 inhibitors biomarkers ER stress Ezetimibe ischemia-reperfusion ionizing radiation liver hydroperoxide epigenetics miR7/MAFG/Nrf2 axe |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Modulators of Oxidative Stress |
| Record Nr. | UNINA-9910557769603321 |
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Saso Luciano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Advances in Melanoma
| New Advances in Melanoma |
| Autore | Larribère Lionel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (148 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
melanoma
targeted therapies BRAF druggable mutations real-time PCR NGS assay immune escape microRNA transporter associated with antigen processing incidence population-based study epidemiology Spain skin cancer single-cell transcriptome sequencing treatment response pseudotime analysis treatment ubiquitination miRNAs embryogenesis melanoblasts melanoblast NF1 transcriptome RNAseq Trp-1 metastasis animal models lung mice |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566475303321 |
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Larribère Lionel
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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