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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (418 p.) |
| Soggetto topico | Biotechnology |
| Soggetto non controllato |
activation induced deaminase
AID/APOBEC alternative splicing anti-cancer artificial intelligence bioinformatics Bioinformatics tool biomarker discovery biomarker signature biomarkers biostatistics brain brain metastases breast cancer breast cancer detection breast cancer prognosis Bufadienolide-like chemicals cancer cancer biomarker cancer biomarkers cancer CRISPR cancer modeling cancer prognosis cancer treatment cancer-related pathways cell-free DNA chemotherapy circulating tumor DNA (ctDNA) classification clinical/environmental factors colorectal cancer comorbidity score Computational Immunology concatenated deep feature copy number aberration copy number variation curation curative surgery datasets decision support systems deep learning denoising autoencoders differential gene expression analysis diseases genes DNA DNA sequence profile drug resistance epigenetics erlotinib estrogen extreme learning false discovery rate feature extraction and interpretation feature selection firehose functional analysis gefitinib gene expression analysis gene inactivation biomarkers gene loss biomarkers gene signature extraction genomic instability GEO DataSets head and neck cancer health strengthening herb hierarchical clustering analysis high-throughput analysis histopathological imaging histopathological imaging features HNSCC hormone sensitive cancers HP hTERT imaging independent prognostic power interaction intratumor heterogeneity knockoffs KRAS mutation locoregionally advanced machine learning meta-analysis methylation microarray miRNA miRNAs mitochondrial metabolism mixture of normal distributions molecular mechanism molecular subtypes Monte Carlo mortality multiple-biomarkers mutable motif mutation Neoantigen Prediction network analysis Network Analysis network pharmacology network target neurological disorders next generation sequencing observed survival interval omics omics profiles oral cancer ovarian cancer overall survival pancreatic cancer pathophysiology PD-L1 precision medicine predictive model protein R package RNA self-organizing map single-biomarkers single-cell sequencing skin cutaneous melanoma somatic mutation StAR steroidogenic enzymes survival analysis TCGA TCGA mining telomerase telomeres The Cancer Genome Atlas traditional Chinese medicine transcriptional signatures treatment de-escalation tumor tumor infiltrating lymphocytes tumor microenvironment variable selection |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Brain Hypoxia and Ischemia: New Insights Into Neurodegeneration and Neuroprotection
| Brain Hypoxia and Ischemia: New Insights Into Neurodegeneration and Neuroprotection |
| Autore | N Nalivaeva Natalia |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 online resource (162 p.) |
| Soggetto topico |
Neurosciences
Science: general issues |
| Soggetto non controllato |
Alzheimer's disease
fatty acids heat acclimation homocysteine hypothermia hypoxic preconditioning ischemic tolerance miRNAs mitochondria nanoparticles neurodegeneration neuroprotection prenatal hypoxia |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Brain Hypoxia and Ischemia |
| Record Nr. | UNINA-9910557697003321 |
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N Nalivaeva Natalia
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology
| Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology |
| Autore | Fioravanti Antonella |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (320 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
acute myocardial infarction
ALS Alzheimer's disease antioxidants antisense oligonucleotide apoptosis ASH autophagy beta cells breast cancer cancer chemoresistance clinical trial cross-talk diabetes endometriosis endometriosis-associated ovarian cancer epithelial-to-mesenchymal transition HBV HCC HCV high-grade serous ovarian cancer Huntington's disease hypoxia liver cancer long noncoding RNA metabolism microRNA MicroRNA MicroRNA (miRNA) microRNAs miR-27a-5p miR526b miR655 miRNA miRNAs mitochondrial dysfunction n/a NAFLD NASH neurodegeneration NF-κB nitrosative stress. exosome noncoding RNA nucleic acid medicine osteoarthritis oxidative stress pancreatic cancer Parkinson's disease physiology reactive oxygen species reactive oxygen species (ROS) redox signaling resistin ROS signal transduction siRNA superoxide (SO) synovial fibroblasts synovitis systemic lupus erythematosus therapeutic resistance therapeutic target therapeutic tolerance Thioredoxin Reductase 1 (TXNRD1) thyroid hormone translation regulation visfatin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557526003321 |
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Fioravanti Antonella
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Developments in bovine immunology [[electronic resource] ] : an integrated view / / edited by Kieran G. Meade
| Developments in bovine immunology [[electronic resource] ] : an integrated view / / edited by Kieran G. Meade |
| Autore | Kieran G. Meade |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 online resource (102 pages) : illustrations, charts |
| Disciplina | 636.2/0896 |
| Collana | Frontiers Research Topics |
| Soggetto topico |
Bovine studies
Immunology |
| Soggetto non controllato |
Pregnancy
Mastits M bovis miRNAs Bovine Immunology Map immunobiotics One Health |
| ISBN | 9782889196326 (ebook) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137090803321 |
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Kieran G. Meade
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| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Innovations in the Integrated Management of Breast Cancer
| Innovations in the Integrated Management of Breast Cancer |
| Autore | Franceschini Gianluca |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (278 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
acellular dermal matrix (ADM)
adjuvant treatment advanced breast cancer aesthetic and oncological outcomes AMH artificial intelligence breast cancer breast cancer treatment breast pathology breast surgery breast ultrasound breast-conserving surgery CDK4/6 inhibitor CDK4/6 inhibitors chemotherapy clinical trial conventional CT and CT angiography DataMart DIEP flap planning ductal breast cancer endocrine resistance evidence-based medicine frailty gene profiling healthcare hepatic surgery histology hormone expression hormone receptor image-guided localization immediate breast reconstruction immune system in situ breast cancer integrated therapies large database liver metastases lobular breast cancer locally advanced breast cancer locoregional therapy lung cancer lymphatic microsurgery lymphaticovenous anastomosis lymphedema machine learning metabolic derangements metastatic breast cancer mini-invasive treatment miRNAs mTOR inhibitor multidisciplinary multidisciplinary treatment n/a neoadjuvant chemotherapy networks next-generation-sequencing nipple-sparing mastectomy non-palpable breast lesions normal breast old age older cancer patients oligometastatic breast cancer oncological outcomes oncology Oncotype Dx osteoclast-like giant cells ovarian reserve patient enrollment patient quality of life personalization personalized medicine personalized treatment physical performance precision medicine predictive model pregnancy pregnancy desire preoperative breast localization quality of life radiotherapy rare breast cancer real world data sarcopenia sentinel lymph node standardized data collection subtypes breast cancer survival systemic treatment tailoring target therapy vascularized lymph node transfer vitamin D web app |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566478003321 |
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Franceschini Gianluca
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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MicroRNA and Cancer
| MicroRNA and Cancer |
| Autore | Tucci Paola |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (298 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
2'-O-methylation
adipokines B-CLL bioinformatics analysis biomarker blood biomarker brain tumour breast cancer Breast cancer cancer stem cell cancer stem cells ccRCC circulating biomarkers circulating microRNA colon cancer Cyclooxygenase-2 (COX-2) deformability diagnosis endometrial cancer estrogens exosome head and neck squamous cell carcinoma hepatocellular carcinoma hyperinsulinemia Hypoxia inducible factor 1-alpha (HIF-1α) immune checkpoint inhibitors immunotherapy insulin insulin resistance insulin signaling insulin-like growth factors malignant melanoma medulloblastoma meta-analysis metastasis metastatic melanoma methylation microRNA MicroRNA (miRNA) microRNAs Migration miR-584-5p miR526b miR655 miRNA miRNA-transcription factor network miRNAs n/a non-small cell lung cancer normal B-cell development ovarian cancer Oxidative stress PARP PI3K/Akt plasma prediction prognosis prognostic factor progression Prostaglandin E2 receptor 4 (EP4) pseudouridylation RCC regulation renal cancer replication stress serum LDH smoking snoRNA stem cells stemness subgroups survival targeted therapy therapy YKT6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213503321 |
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Tucci Paola
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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MicroRNA as Biomarkers in Cancer Diagnostics and Therapy / Lorenzo F. Sempere
| MicroRNA as Biomarkers in Cancer Diagnostics and Therapy / Lorenzo F. Sempere |
| Autore | Sempere Lorenzo F |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (166 p.) |
| Soggetto topico | MicroRNAs |
| Soggetto non controllato |
leukemia
cell lines hepatitis B virus long non coding RNA normalization of miRNA expression in RT-qPCR children colorectal review bevacizumab tumor budding cells oral cancer liquid biopsy hepatocellular carcinoma small t-antigen colorectal cancer protein-miRNA complex biomarkers biomarker interleukin-1? tissue analysis miRNAs T-cell acute lymphoblastic leukemia (T-ALL) leukoplakia inflammation exosomes circulating free DNA hepatitis C virus miRNA miR-21 extracellular microRNA endogenous controls lymphoma confocal slide scanning microscopy early diagnosis reference genes large T-antigen microRNA miRNA (microRNA) cancer TNF-? plasma |
| ISBN |
9783039212507
3039212508 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346847003321 |
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Sempere Lorenzo F
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Psychiatry
| Molecular Psychiatry |
| Autore | Rein Theo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (288 p.) |
| Soggetto topico |
Medicine and Nursing
Mental health services |
| Soggetto non controllato |
(2R,6R)-Hydroxynorketamine
5-HT 4 receptor 5-HT4R acid sphingomyelinase actin dynamics affective temperament alcohol dependence alpha-synuclein Alzheimer's disease antidepressant antidepressant treatment antidepressants antipsychotics basic-helix-loop-helix BDNF behavior biomarker discovery biomarkers bipolar disorder brain cardiovascular disease cell adhesion molecules chemokines childhood-onset schizophrenia (COS) circadian rhythms coactivator cognition copy number variation (CNV) cordance CRMP-2 CyP40 cytoskeleton dendritic arborization depression DISC1 DNA methylation dopaminergic gene polymorphisms DRR1 drug design early neurodevelopment electroconvulsive therapy endocrinology expression FAM107A FKBP5 FKBP51 FKBP52 forced swimming gender gene expression general cognitive function genetic correlation glucocorticoids GR GWAS Hamilton Scale of Depression hippocampus HPA axis Hsp90 Immune response immunohistochemistry immunology induced pluripotent stem cell (iPSC) inflammation intelligence Ketamine liver enzymes machine learning major depression major depressive disorder mineralocorticoid receptor knockout miRNAs molecular chaperones mood disorder multi-target drugs multi-task learning n/a nervous system neurodevelopment neuroinflammation neuronal differentiation obesity Parkinson's disease polypharmacology PP5 PPARγ proteomics PSA-NCAM psychiatric disease psychiatry rapid-acting resilience response variability Roman rat lines schizophrenia serotonin sex difference sleep sleep EEG SNCA social defeat sphingolipid metabolism steroid hormones stress stress physiology stress response susceptibility synapse T cells Th17 cells transcription biology Treg cells trkB TU3A western blot withdrawal |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557793503321 |
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Rein Theo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Multi-Omics for the Understanding of Brain Diseases
| Multi-Omics for the Understanding of Brain Diseases |
| Autore | Yoon Jong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (204 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
3D culture
abnormal behavior gene set ageing Alzheimer's disease biomarker brain ceramides chloride adducts chromosome 22q11.21 CNV copy number variant CSF de novo mutation DGCR8 differentially expressed genes epigenetics epigenome flow infusion analysis genetic polymorphism glycerophosphocholines human brain hydrogen peroxide lab-on-chip microfluidics miRNAs morphine n/a NAD+ neurological diseases neuroprotective neurotransmitter newborn infant nicotinamide OpenArray organ-on-chip Orthosiphon stamineus plant-derived proteins plasma PPI proteomics region schizophrenia SH-SY5Y cell model SIDS spatiotemporal network sphingolipids synaptic plasticity withdrawal zinc finger domain zinc finger motif zinc finger proteins zinc metalloproteins |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557349303321 |
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Yoon Jong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neuroprotection: Rescue from Neuronal Death in the Brain
| Neuroprotection: Rescue from Neuronal Death in the Brain |
| Autore | Lee Bae Hwan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (408 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
acid-sensing ion channels
adenoviral vector adiponectin aging Alzheimer's disease amiloride amyloid-beta amyotrophic lateral sclerosis antioxidant antioxidants apoptosis ascorbic acid astrocytes astrocytic networks axotomy BDNF bean phosphatidylserine (Bean-PS) blood brain barrier brain brain targeting brain-derived neurotrophic factor calcium activity catecholamines cation-chloride cotransporters cell death choline acetyltransferase (ChAT) connexin 43 cortisol CRISPR/cas9 depression electroneutral transport endotheline-1 excitotoxicity GDNF gerbil glia glioblastoma global cerebral ischemia GPR4 receptor hippocampus homocysteine human umbilical cord blood mononuclear cells inflammation insulin ischemia ischemic stroke KCCs lactate lipid emulsion liver growth factor MEK/ERK metabolic disease microglia middle cerebral artery occlusion miRNAs moderate hypoxia motoneurons MPP+ N-acetyl-l-cysteine n/a nanoparticle-based drug delivery NCAM neural injury neurodegeneration neurodegenerative disease neurodegenerative disorder neurogenesis neuronal death neuroprotection nimodipine nitrite NKCCs oculomotor system organotypic hippocampal slice culture oxidative stress oxygen-glucose deprivation Parkinson's disease PGC-1α physical exercise PI3K/AKT preventive gene therapy psychomotor function pyridoxine deficiency reaction time reperfusion injury sodium-hydrogen exchanger-1 status epilepticus stroke subarachnoid haemorrhage synaptic plasticity Tg2576 transgenic mice transient receptor potential melastatin 2 trimethyltin (TMT) trophic factors vascular endothelial growth factor vascular endothelial growth factor receptor 2 VEGF WNK-SPAK/OSR1 zinc |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Neuroprotection |
| Record Nr. | UNINA-9910557716703321 |
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Lee Bae Hwan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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