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A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder
| A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder |
| Autore | Frye Richard E |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
fecal metabolites
ASD microbiome gastrointestinal symptoms Fisher Discriminant Analysis digital biomarkers wearables time series analysis autism social dyads socio-motor parameters network connectivity non-linear complex dynamics stochastic analysis autism spectrum disorders copy number variants females Array-Comparative Genomic Hybridization (Array-CGH) autism spectrum disorder Ehlers-Danlos syndrome hypermobility spectrum disorders autonomic disorder mast cell activation syndrome genetic testing chromosomal microarray analysis whole exome sequencing whole genome sequencing clinical utility polygenic risk scores Temple Grandin biomarker omics precision medicine proteomics transcriptomics epigenetics metabolomics patient stratification mitochondria oxidative stress prenatal environment immune dysfunction immunoglobulin G intravenous immunoglobulin energy metabolism fatty acid oxidation acyl-carnitines resveratrol integrative model concomitant condition disorder autism spectrum disorder (ASD) genomics personalized treatment strategy single nucleotide polymorphisms clinical decision support tool ADHD PANDAS OCD anxiety folate receptor alpha folates pregnancy brain development fetal development cobalamin glutathione methylation methylcobalamin redox metabolism locked-in network syndrome resting-state functional magnetic resonance imaging temporal lobe epilepsy amygdala brain COVID-19 children cytokines flavonoids inflammation luteolin mast cells microglia SARS-CoV-2 stress nutraceuticals survey vitamins minerals B12 folinic acid quality of life parents intervention systematic review medical claims logistic regression analysis retrospective analysis associated risk monoamine neurotransmitters neurotransmitter deficiency cerebral folate deficiency folate receptor alpha autoantibodies leucovorin α-amylase cortisol heart rate variability neuromodulation sleep anxiety transdermal electrical neuromodulation neurostimulation |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595075503321 |
Frye Richard E
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (418 p.) |
| Soggetto non controllato |
cancer treatment
extreme learning independent prognostic power AID/APOBEC HP gene inactivation biomarkers biomarker discovery chemotherapy artificial intelligence epigenetics comorbidity score denoising autoencoders protein single-biomarkers gene signature extraction high-throughput analysis concatenated deep feature feature selection differential gene expression analysis colorectal cancer ovarian cancer multiple-biomarkers gefitinib cancer biomarkers classification cancer biomarker mutation hierarchical clustering analysis HNSCC cell-free DNA network analysis drug resistance hTERT variable selection KRAS mutation single-cell sequencing network target skin cutaneous melanoma telomeres Neoantigen Prediction datasets clinical/environmental factors StAR PD-L1 miRNA circulating tumor DNA (ctDNA) false discovery rate predictive model Computational Immunology brain metastases observed survival interval next generation sequencing brain machine learning cancer prognosis copy number aberration mutable motif steroidogenic enzymes tumor mortality tumor microenvironment somatic mutation transcriptional signatures omics profiles mitochondrial metabolism Bufadienolide-like chemicals cancer-related pathways intratumor heterogeneity estrogen locoregionally advanced RNA feature extraction and interpretation treatment de-escalation activation induced deaminase knockoffs R package copy number variation gene loss biomarkers cancer CRISPR overall survival histopathological imaging self-organizing map Network Analysis oral cancer biostatistics firehose Bioinformatics tool alternative splicing biomarkers diseases genes histopathological imaging features imaging TCGA decision support systems The Cancer Genome Atlas molecular subtypes molecular mechanism omics curative surgery network pharmacology methylation bioinformatics neurological disorders precision medicine cancer modeling miRNAs breast cancer detection functional analysis biomarker signature anti-cancer hormone sensitive cancers deep learning DNA sequence profile pancreatic cancer telomerase Monte Carlo mixture of normal distributions survival analysis tumor infiltrating lymphocytes curation pathophysiology GEO DataSets head and neck cancer gene expression analysis erlotinib meta-analysis traditional Chinese medicine breast cancer TCGA mining breast cancer prognosis microarray DNA interaction health strengthening herb cancer genomic instability |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
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Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Classification of Lymphomas and Hematological Neoplasia in the Era of Genomic Research : A Themed Issue in Honor of Dr. Elaine S. Jaffe
| Classification of Lymphomas and Hematological Neoplasia in the Era of Genomic Research : A Themed Issue in Honor of Dr. Elaine S. Jaffe |
| Autore | Nicolae Alina |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (252 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
lymphomas in PLWH
KSHV/HHV8 EBV lymphoma classification management cART HLX HOXB9 NFIB PBX1 STAT3 TLX2 autoimmune hemolytic anemia cold agglutinin B-cell lymphoproliferative disorder lymphomagenesis methylation histone modification indolent T-cell NK-cell lymphoproliferative disorder gastrointestinal tract genetics cell of origin T follicular helper cells TFH lymphoma angioimmunoblastic T-cell lymphoma follicular T-cell lymphoma peripheral T-cell lymphoma of T-follicular helper immunophenotype peripheral T-cell lymphoma primary cutaneous B-cell lymphoma primary cutaneous marginal zone B-cell lymphoma primary cutaneous follicle centre lymphoma primary cutaneous diffuse large B-cell lymphoma, leg-type primary cutaneous diffuse large B-cell lymphoma, not otherwise specified intravascular B-cell lymphoma EBV+ mucocutaneous ulcer Burkitt lymphoma epidemiology Plasmodium falciparum Epstein Barr virus registry studies multimodal cancer non-Hodgkin lymphoma HIV/AIDS follicular lymphoma in situ follicular neoplasia FL transformation FL in young patients diffuse large B-cell lymphoma NOS high grade B-cell lymphoma lymphoma gene expression profiling tumor microenvironment diagnostics centrocytic lymphoma intermediate lymphocytic lymphoma Jaffe mantle cell lymphoma mantle zone lymphoma cyclin D1 lymphomas people living with HIV tumor prevention in people living with HIV KSHV BCL2 rearrangement genetic alterations histological transformation targeted therapies transformed follicular lymphoma lymphoproliferative neoplasms of uncertain biological significance monoclonal B-cell lymphocytosis “in situ” follicular neoplasia “in situ” mantle cell neoplasia atypical germinal centers large B-cell lymphoma with IRF4 rearrangement “in situ” high-grade B lymphomas Hodgkin lymphoma |
| ISBN | 3-0365-5744-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Classification of Lymphomas and Hematological Neoplasia in the Era of Genomic Research |
| Record Nr. | UNINA-9910637783903321 |
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Nicolae Alina
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Colorectal Cancers: From Present Problems to Future Solutions
| Colorectal Cancers: From Present Problems to Future Solutions |
| Autore | Allgayer Heike |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
Phage
bacteriophages diet infection colorectal cancer nutrition circulating tumor cells colorectal cancer EPISPOT assay CellSearch® system predictive value chromatin density nanoscale tumour cell heterogeneity microRNAs metastasis super-resolution microscopy early onset cohort epidemiology liquid biopsy biomarker indirect carcinogenesis bovine meat and milk factors (BMMF) chronic zoonosis multiplex tumor immunology immune landscape spontaneous feline intestinal tumors comparative oncology tumor budding CTNNB1 genome-wide methylation array methylation miRNA colon cancer personalized treatment drug combinations Matrix Metalloproteinases (MMPs) polyp TIMPs MMP polymorphisms MMP targeting S100A4 DKK1 Wnt signaling patient survival gender rectal cancer radiochemotherapy radiosensitivity DNA double-strand breaks deposited energy quality of life blood values (molecular) carcinogenesis cancer progression (single) cancer cell heterogeneity models infectious agents (targeted) therapy personalized medicine |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Colorectal Cancers |
| Record Nr. | UNINA-9910585937103321 |
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Allgayer Heike
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational Methods for the Analysis of Genomic Data and Biological Processes
| Computational Methods for the Analysis of Genomic Data and Biological Processes |
| Autore | Gómez Vela Francisco A |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (222 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
HIGD2A
cancer DNA methylation mRNA expression miRNA quercetin hypoxia eQTL CRISPR-Cas9 single-cell clone fine-mapping power RNA N6-methyladenosine site yeast genome methylation computational biology deep learning bioinformatics hepatocellular carcinoma transcriptomics proteomics bioinformatics analysis differentiation Gene Ontology Reactome Pathways gene-set enrichment meta-analysis transcription factor binding sites genomics chilling stress CBF DREB CAMTA1 pathway text mining infiltration tactics optimization algorithm classification clustering microarray ensembles machine learning infiltration computational intelligence gene co-expression network murine coronavirus viral infection immune response data mining systems biology obesity differential genes expression exercise high-fat diet pathways potential therapeutic targets DNA N6-methyladenine Chou's 5-steps rule Convolution Neural Network (CNN) Long Short-Term Memory (LSTM) machine-learning chromatin interactions prediction genome architecture |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557129603321 |
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Gómez Vela Francisco A
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Creatine Supplementation for Health and Clinical Diseases
| Creatine Supplementation for Health and Clinical Diseases |
| Autore | Kreider Richard B |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (562 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
ergogenic aids
cellular metabolism phosphagens sarcopenia cognition diabetes creatine synthesis deficiencies concussion traumatic brain injury spinal cord injury muscle atrophy rehabilitation pregnancy immunity anti-inflammatory antioxidant anticancer creatine nutritional supplements fertility newborn development brain injury post-viral fatigue syndrome chronic fatigue syndrome GAA creatine kinase dietary supplements exercise skeletal muscle glycemic control type 2 diabetes mellitus phosphorylcreatine dietary supplement ergogenic aid youth athletes osteoporosis osteosarcopenia frailty cachexia innate immunity adaptive immunity inflammation macrophage polarization cytotoxic T cells toll-like receptors vascular pathology cardiovascular disease oxidative stress vascular health female menstrual cycle hormones exercise performance menopause mood children height BMI-for-age stature-for-age growth phosphocreatine creatine transporter supplementation treatment heart heart failure ischemia myocardial infarction anthracycline cardiac toxicity energy metabolism cell survival bioinformatics systems biology cellular allostasis dynamic biosensor pleiotropic effects of creatine (Cr) supplementation inflammatory bowel diseases (IBD) ulcerative colitis Crohn’s disease creatine kinase (CK) phosphocreatine (PCr) creatine transporter (CrT) intestinal epithelial cell protection intestinal tissue protection creatine perfusion organ transplantation Adenosine mono-phosphate (AMP) activated protein kinase (AMPK) liver kinase B1 (LKB1) mitochondrial permeability transition pore (mPTP) reactive oxygen species (ROS) glucose transporter (GLUT) T cell antitumor immunity metabolic regulator cancer immunotherapy supplements muscle damage recovery immobilization atrophy muscular dystrophy amyotrophic lateral sclerosis Parkinson’s Disease cardiopulmonary disease mitochondrial cytopathy hypertrophy athletic performance weightlifting resistance exercise training muscular power muscular adaptation muscle fatigue adipose tissue muscle strength physiological adaptation mitochondria thermogenesis MAP kinase signaling system sodium-chloride-dependent neurotransmitter symporters signal transduction intradialytic creatine supplementation hemodialysis muscle protein energy wasting clinical trial muscle weakness chronic fatigue cognitive impairment depression anemia resistance training sports nutrition strength toxicity methylation hyperhomocysteinemia neuromodulation MCDA mitochondriopathia cardiac infarction long COVID hypoxia stroke neurodegenerative diseases noncommunicable disease adenosine 5′-monopnophosphate-activated protein kinase anthracyclines creatine supplementation cardiac signaling cardiotoxicity doxorubicin soy vegetarian/vegan diet amino acids dietary ingredients performance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566476003321 |
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Kreider Richard B
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Derivatization in Analytical Chemistry
| Derivatization in Analytical Chemistry |
| Autore | Tzanavaras Paraskevas D |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (210 p.) |
| Soggetto topico |
Research & information: general
Chemistry Analytical chemistry |
| Soggetto non controllato |
tyrosine kinase inhibitors
chloranilic acid charge-transfer reaction 96-microwell spectrophotometric assay high-throughput pharmaceutical analysis biogenic amines Lycium barbarum L. HPLC derivatization amino acids esterification GC–MS pentafluoropropionic anhydride stability toluene pigment linseed oil derivatisation quantification P/S ratio A/P ratio ∑D GC-MS ureide BSTFA creatine creatinine silylation TMS validation low-molecular-weight thiols human serum albumin α-lipoic acid blood plasma monobromobimane reduction sodium borohydride high-performance liquid chromatography fluorescence detection taurine glutamine clams high-resolution mass spectrometry nerve agents methylation chemical warfare agents sarin Novichoks 2-naphthalenethiol sulforaphane HPLC-UV/Vis pharmacokinetics acetonitrile-related adducts acetylenic lipids double and triple bond localization in-source derivatization mass spectrometry acetazolamide carbonic anhydrase enhancement inhibition pentafluorobenzyl bromide chiral metabolomics rice water d-amino acids enantiomer separation dimethyl labeling homocysteine thiolactone homocysteine zone fluidics o-phthalaldehyde fluorosurfactant-modified gold nanoparticles |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576885703321 |
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Tzanavaras Paraskevas D
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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MicroRNA and Cancer
| MicroRNA and Cancer |
| Autore | Tucci Paola |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (298 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Breast cancer
Hypoxia inducible factor 1-alpha (HIF-1α) MicroRNA (miRNA) miR526b miR655 Oxidative stress Migration Cyclooxygenase-2 (COX-2) Prostaglandin E2 receptor 4 (EP4) PI3K/Akt adipokines endometrial cancer estrogens hyperinsulinemia insulin insulin resistance insulin signaling insulin-like growth factors microRNA miRNA ovarian cancer survival prognostic factor serum LDH blood biomarker circulating microRNA plasma immunotherapy immune checkpoint inhibitors metastatic melanoma hepatocellular carcinoma metastasis exosome bioinformatics analysis renal cancer RCC ccRCC meta-analysis miRNAs normal B-cell development B-CLL miRNA-transcription factor network regulation biomarker therapy prognosis diagnosis progression prediction smoking non-small cell lung cancer methylation miR-584-5p YKT6 snoRNA 2'-O-methylation pseudouridylation malignant melanoma cancer stem cell stemness head and neck squamous cell carcinoma colon cancer cancer stem cells microRNAs deformability PARP replication stress targeted therapy breast cancer circulating biomarkers medulloblastoma brain tumour subgroups stem cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213503321 |
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Tucci Paola
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Pathways in Cancers
| Molecular Pathways in Cancers |
| Autore | Cristóbal Ion |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (284 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
actin cytoskeletal reorganization
breast cancer CD99 agonist EGFR dimerization endocytosis FAK dephosphorylation PTPN12 Rac1 RhoA tripeptide OMD PRELP tumor suppression gene bladder cancer initiation tight junction partial EMT tousled-like kinase (TLK) NIMA-related kinase 1 (NEK1) yes-associated protein 1 (YAP1) thioridazine (THD) MS-determined phosphopeptides human immunodeficiency virus type 1 epithelial cells carcinogenicity oxidative stress reactive oxygen species gp120 Tat Nef matrix protein p17 reverse transcriptase mitochondria metastasis OXPHOS cancer Warburg effect cancer therapeutics myeloproliferative neoplasms signaling pathways JAK2 CALR MPL TPOR DUSP1 MAPK Snail prostate cancer migration and invasion patient survival biomarkers pBRD4 SET PP2A prognosis triple negative breast cancer resistance anti-receptor therapy trastuzumab PI3K mTOR TAK-228 epigenetic methylation acetylation non-coding RNA small-cell lung cancer triple-negative breast cancer pancreatic ductal adenocarcinoma glioblastoma metastatic melanoma advanced ovarian cancer hepatocellular carcinoma immune evasion immunotherapy immune checkpoint inhibitors oncogenic signaling pathway molecular targeted agents genome epigenome tumor immune microenvironment ovarian cancer adaptive immunity innate immunity complement system cancer immunology tumor microenvironment splicing pathway luminal breast cancer BET inhibitors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566473703321 |
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Cristóbal Ion
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural Compounds as New Cancer Treatments
| Natural Compounds as New Cancer Treatments |
| Autore | Barrajon Enrique |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (128 p.) |
| Soggetto non controllato |
microbiota
treatment sulforaphane synergy epigenetic natural compound xenohormesis anticancer miR-663 tyrosine kinase inhibitors acetylation epidemiology double-blinded inflammation bladder cancer polypharmacology animal model synbiotics resveratrol royal jelly 5-aza-2'-deoxycytine saponins phenolics cardiovascular disease antioxidant colorectal cancer trypsin inhibitors seeds green tea Gac randomized clinical trial melanoma adverse events extraction microbiome Momordica cochinchinensis freeze dried extract renal cell carcinoma methylation cancer probiotics |
| ISBN | 3-03921-366-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367758003321 |
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Barrajon Enrique
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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