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Advances in Nanomaterials in Biomedicine
| Advances in Nanomaterials in Biomedicine |
| Autore | Ryabchikova Elena I |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (472 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
bone marrow-derived mesenchymal stromal cells
rAAV vectors carbon dots SOX9 TGF-β cartilage repair silver nanoparticles Entada spiralis Ceiba pentandra antibacterial assay catalytic dye reduction osteoarthritis human articular cartilage polymeric micelles pro-inflammatory cytokines IL-1β TNF-α nanomaterials nanomedicine immunotherapy oncotherapy immune-checkpoint inhibitors immunogenic cell death nano-vaccines nano-conjugates immune response oxidative stress antioxidants nanoparticles biological nano-antioxidants gold nanoparticles radiation chemotherapy radiosensitizer drug delivery system chemoradiotherapy magnetoliposomes hydrogels magnetolipogels self-assembly fluorescence Förster resonance energy transfer polypropylenimine dendrimers polyethylenimines tyrosine-modified polypropylene-imines tyrosine-modified polyethlyenimines PPI-Y siRNA transfection polymeric nanoparticles carbosilane dendron triazine amphiphile vesicles pH-sensitive doxorubicin methotrexate leukaemia molecular ultrasound nanobubbles active targeting targeted microbubbles angiogenesis inflammation thrombosis clinical translation molecular imaging liver fibrosis diagnosis therapy theranostics targeted drug delivery lipid conjugates amphiphilic oligonucleotides phosphoryl guanidines nucleic acid delivery leukemia iron nanoparticles RNA-Seq cytotoxicity polymers biodegradable drug delivery pharmaceutical SQUID magnetic properties iron content magnetite nanoparticles superoxide aorta heart nano-biomaterials nanotechnology scaffolds hard tissue engineering AuNPs AuPEI-NPs AuBSA-NPs electron microscopy ultrastructure of HepG2 cells and spheroids ultrastructure of HEK293 cells and spheroids penetration of NPs into monolayer and spheroids gold nanostars photothermal therapy photoacoustic imaging computed tomography cancer theranostic agents biocompatible nanomaterials diagnostics nanocarriers tissue engineering |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557724003321 |
Ryabchikova Elena I
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Clay-Based Pharmaceutical Formulations and Drug Delivery Systems
| Clay-Based Pharmaceutical Formulations and Drug Delivery Systems |
| Autore | Viseras César |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
hydrochlorothiazide
cyclodextrins sepiolite nanoclay dissolution rate tablet electrospinning chitosan chondroitin sulfate scaffolds montmorillonite halloysite fibroblasts proliferation immune response glycosaminoglycans antimicrobial properties palygorskite spring water hydrogel fibroblast biocompatibility wound healing mesoporous clay Neusilin aeroperl liquisolid technique glyburide dissolution improvement hydrotalcite ketoprofen hybrid photostability hydrogel film bioadhesion heavy metal hazardous element element mobility clay minerals toxicity palygorksite proliferation Franz cell bioactive elements praziquantel drug organic solvents in vitro dissolution tests cytotoxicity targeted drug delivery halloysite nanotube osteosarcoma methotrexate surface modification |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557129803321 |
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Viseras César
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics
| Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics |
| Autore | Tutone Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (387 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
3D-QSAR
pharmacophore modeling ligand-based model HDACs isoform-selective histone deacetylase inhibitors aminophenylbenzamide hERG toxicity drug discovery fingerprints machine learning deep learning gene expression signature drug repositioning approaches RNA expression regulation high-throughput virtual screening dual-target lead discovery neurodegenerative disorders Alzheimer's disease dual mode of action multi-modal nicotinic acetylcholine receptor acetylcholinesterase molecular docking methotrexate drug resistance human dihydrofolate reductase virtual screening molecular dynamics simulation epitope binning epitope mapping epitope prediction antibody:antigen interactions protein docking glycoprotein D (gD) herpes simplex virus fusion proteins Src inhibitors pharmacophore model molecular dynamics simulations in silico COX-2 inhibitors molecular modeling sodium-glucose co-transporters 2 FimH uropathogenic bacteria urinary tract infections diabetes drug-resistance mutations HIV-2 protease structural characterization induced structural deformations SARS-CoV-2 COVID-19 multiprotein inhibiting natural compounds MD simulation 3CL-Pro antivirals docking simulations drug repurposing consensus models binding space isomeric space MRP4 SNPs variants protein threading modeling molecular dynamics binding site hTSPO PK11195 cholesterol homology modeling molecular dynamics (MD) simulation carbon nanotubes Stone-Wales defects haeckelite defects doxorubicin encapsulation drug delivery system binding free energies noncovalent interactions main protease mutants inhibitors PF-00835231 Mycobacterium tuberculosis tuberculosis proteasome natural compounds multiscale multitargeting polypharmacology computational biology drug repositioning structural bioinformatics proteomic signature skin aging oxidative stress aging progression mechanism genome-wide genetic and epigenetic network (GWGEN) systems medicine design multiple-molecule drug immunoproteasome non-covalent inhibitors MD binding metadynamics induced-fit docking |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Computational Approaches |
| Record Nr. | UNINA-9910557519403321 |
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Tutone Marco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Delivery of siRNA Therapeutics
| Drug Delivery of siRNA Therapeutics |
| Autore | Lamberti Gaetano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
oligonucleotide delivery
light-activated release intracellular release liposome indocyanine green drug co-delivery methotrexate siRNA antitumor effect mixed micelles targeted delivery system cationic liposome folate folate receptor cationic cholesterol derivative siRNA delivery gene knockdown tumor-targeting VEGFA VEGFR1 endoglin peptide angiogenesis gene silencing migration proliferation endothelial cells RNAi therapeutics amphiphilic dendrons PAMAM dendrimers self-assembling nanovectors covalent dendrimers NABDs liposomes clinical trials drug delivery nanoparticle carbonate apatite ERBB2 AKT breast cancer ovarian cancer polymer lipid delivery poly(ethylene) imine PEI RNA tyrosine-modification tumor xenograft magnetic nanoparticle iron oxide BCL2 BIRC5/survivin oral cancer aptamers cancer nanoparticles STAT6 polyaspartamide pegylation polyamine polyplexes asthma |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557498903321 |
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Lamberti Gaetano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Free Radical Research in Cancer
| Free Radical Research in Cancer |
| Autore | Čipak Gašparović Ana |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (192 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
NQO1
NQO1*2 polymorphism quinone breast cancer menadione lapachone doxorubicin ascorbate oxidative stress reactive oxygen species sperm cancer chemotherapy antioxidant therapy antioxidant proteins chemoresistance oxaliplatin 5-Fluorouracil myelodysplastic syndromes carbonylation deferasirox ovary calcium channel Trolox granulosa cell tumor cell death mitochondria photodynamic therapy singlet oxygen nitric oxide light combination therapy antioxidants bleomycin cancer treatment chemotherapy-induced toxicity cisplatin free radicals methotrexate ozone therapy lung cancer cancer metabolism reactive oxygen species (ROS) therapy resistance new therapeutic strategies breast cancer stem cells 4-hydroxy-2-nonenal extracellular matrix NRF2 bardoxolone methyl prostate cancer castration-resistant prostate cancer androgen receptor (AR), AR-V7 anti-androgen enzalutamide androgen deprivation therapy cancer antioxidant triphala ayurveda chemoprevention and chemotherapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557152603321 |
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Čipak Gašparović Ana
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Interdisciplinary Medicine
| Interdisciplinary Medicine |
| Autore | Diaconu Camelia |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
ectopic kidney
locally advanced cervical cancer nephrectomy skin cancer squamous cell carcinoma basal cell carcinoma malignant melanoma surgery quality of life breast reconstruction timing mastectomy adjuvant therapy fertility preservation cryo-preservation vitrification breast cancer dietary attitude type 2 diabetes mellitus diabetes self-management empowerment approach dietary behavior early stage ovarian cancer para-aortic lymph node metastases synchronous malignancies cervical adenocarcinoma serous ovarian adenocarcinoma PSFT resection pulmonary adenocarcinoma Krukenberg tumors ureteral stenosis chronic kidney disease preeclampsia hypertension proteinuria type 2 diabetes hemoglobin A1c matrix metalloproteinases-2 and -9 anti-elastin antibodies anti-collagen IV antibodies diabetic retinopathy diabetic nephropathy macrovascular complications nephrotic syndrome thrombosis inherited risk factors mutation anticoagulation medical malpractice doctor-patient relationship communication complications diagnostic error preventive measures retrospective study children self-medication risks beliefs Mayer-Rokitansky-Küster-Hauser syndrome primary amenorrhea surgical management vaginal reconstruction plastic surgery oral graft versus host disease topical corticosteroids dexamethasone clobetasol budesonide tuberous sclerosis angiomyolipomatosis uretero-hydronephrosis angiofibromas VCAM-1 E-selectin psoriasis methotrexate adalimumab colosalpingeal fistula enterotubal fistula diverticular fistulation diagnosis hysteroscopy management pregnancy-associated breast cancer Romania primary pleural hydatidosis Albendazole echinoccocus caudal duplication syndrome colorectal duplication genitourinary duplication congenital malformation pediatric surgery SARS-CoV-2 COVID-19 SIADH dyselectrolytemia hyponatremia Silesian Voivodeship gold hour cardiovascular diseases Medical Emergency Team acute cholecystitis laparoscopic cholecystectomy elderly safety young lung cancer depression anxiety multiple correspondence analysis k-means clustering |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557526303321 |
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Diaconu Camelia
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nanomaterials for Biomedical and Biotechnological Applications
| Nanomaterials for Biomedical and Biotechnological Applications |
| Autore | Ferraro Angelo |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (266 p.) |
| Soggetto topico |
Technology: general issues
Biotechnology |
| Soggetto non controllato |
neurodegenerative disease
cerium oxide nanoparticles Parkinson's disease oxidative stress physicochemical properties blood-brain barrier synthesis methods magnetic driving magnetic nanoparticles actuation system drug targeting chitosan clay nanocomposite films papain covalent immobilization wine magnetic gels drug release magnetic hyperthermia magnetic lipogels supramolecular hydrogels self-assembly nanoparticle functionalization organic and inorganic nanoparticles ophthalmic applications clinical trials orthopedic nanomedicine nanomodified surfaces animal model immune response Chlorella vulgaris microwave-synthesized magnetite particles response surface methodology harvesting process optimization optimization economic analysis plant design and process engineering cubic particles COVID-19 nanotechnology vaccines sanitizers biosensors restricted access media nanofibers microfibers on-line extraction biological samples column-switching chromatography theranostic nanomaterials boron nitride neutron capture reaction nuclear medicine drug delivery antibiotics antimicrobial resistance gold nanoparticles ciprofloxacin Enterococcus faecalis liver and kidney infections colorectal cancer biomarkers cytotoxic medication genetic pathways epigenetic changes prognostic phytomedicine rheumatoid arthritis methotrexate anti-arthritic activity nanoemulsion hemocompatibility MTT assay stability studies |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585937903321 |
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Ferraro Angelo
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease: From Bench to Bedside
| Nanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease: From Bench to Bedside |
| Autore | Tagit Oya |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (296 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology Materials science |
| Soggetto non controllato |
poly(lactic-co-glycolic acid) (PLGA)
blood–brain barrier (BBB) current Good Manufacturing Practice (cGMP) Food and Drug Administration (FDA) nanotechnology PLGA nanoparticles neurodegenerative diseases drug delivery central nervous system neuroprotective drugs fluorescent labeling DiI coumarin 6 rhodamine 123 Cy5.5 quantum yield brightness stability of fluorescent label confocal microscopy intracellular internalization in vivo neuroimaging double-emulsion method dry powder inhalation antigen release porous PLGA particles microfluidics methotrexate chitosan PLA/PLGA sustained release micro-implant animal model minimally invasive drug delivery system nanoparticles poly (lactic-co-glycolic acid) (PLGA) microfluidic pharmacokinetics (PK) and biodistribution atorvastatin calcium poly(lactide-co-glycolide) polymeric nanoparticles carrageenan induced inflammation anti-inflammatory radiolabeled nanoparticles nuclear medicine photothermal therapy phthalocyanine SKOVip-kat Katushka TurboFP635 JO-4 PLGA orthotopic tumors 3D culture spheroids poly(lactic-co-glycolic acid) nanomedicine scale-up manufacturing clinical translation inline sonication tangential flow filtration lyophilization downstream processing H. pylori design of experiments poly(lactic-co-glycolic) acid size cancer chemoimmunotherapy immunogenic cell death immune checkpoint blockade PNA5 glycopeptide mas receptor angiotensin PLGA diblock copolymer ester and acid-end capped double emulsion solvent evaporation biocompatible biodegradable cardiovascular nanoparticle solid-state characterization in vitro drug release kinetics modeling PEGylation amine emulsion polyvinyl alcohol (PVA) Pluronic triblock copolymer trehalose sucrose Indomethacin solvents stabilizers morphology particle-size encapsulation drug release cytotoxicity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Nanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease |
| Record Nr. | UNINA-9910580215803321 |
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Tagit Oya
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers
| Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers |
| Autore | Kutner Andrzej |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (450 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
alpha-ketoglutarate
cell cycle apoptosis JNK cell migration cell invasion TGF-β VEGF glycoconjugates methotrexate cancer treatment glucose metabolism drug design and discovery anticancer drugs targeted therapy Warburg effect antidepressants pyrido[1,2-c]pyrimidines dual 5-HT1A/SERT activity drug design anticancer activity lung cancer resveratrol PRI-2191 vitamin D active substance delivery systems biomedical hydrogels active substance-controlled release genistein hydrogels for cosmetology hydrogels for dermatology transdermal active substance delivery systems histone deacetylase (HDAC) depression biomarker anti-depressant therapy human DNA topoisomerase cancer drug molecular docking synthesis fluorine vitamin D3 metabolite A-ring CD-ring side-chain nanoparticles molecular modeling oxidation mechanisms electrochemistry MALDI spectroscopic data cytotoxic study self-assembled monolayer gold electrode multimodal activity calcium-sensing receptor enantiomer calcimimetic calcilytic colon cancer stereospecificity HT-29 IL-8 inflammation cyclooxygenase 1,2,4-triazole pyridazinone SAR anti-inflammatory activity antioxidant activity ADME anticancer drug antimicrobial peptide (AMP) dermaseptin frog skin peptides LHRH prostate cancer Phyllomedusa bicolor therapeutic peptides copper (II) complexes thiourea cytotoxic activity proteome analysis antimicrobial activity major latex protein Chelidonium majus greater celandine defense-related proteins alkaloids cancer cells vitamin D receptor split luciferase-based biosensor CYP24A1-dependent metabolism CYP27B1 rickets genome editing vitamin D biology and action transcription ChIP-chip analysis distal enhancers histone H3 acetylation RNA polymerase II analogue actions at genes vitamin D hormone (1,25(OH)2D3) latex antiviral proteins antimicrobial compounds cytotoxicity drug discovery CRISPR/Cas9 tetrahydro-β-carbolines Plasmodium falciparum (P. falciparum) antimalarial antiparasitic agents hemolysis vitamin D analogs 25 vitamin D 24-hydroxylase CYP24A1 proliferation high-grade serous ovarian cancer cells gold Au(III) complex colorectal cancer organometallic cancer therapy metallodrugs |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585938903321 |
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Kutner Andrzej
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Rheumatoid Arthritis Therapy Reappraisal : Strategies, Opportunities and Challenges
| Rheumatoid Arthritis Therapy Reappraisal : Strategies, Opportunities and Challenges |
| Autore | Müller Rüdiger |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
rheumatoid arthritis
sleep sleep disorders pain osteoporosis fracture fracture risk assessment tool treat-to-target certolizumab pegol csDMARDs glucocorticoids intra-articular injections DAS 28 ACR response HAQ-DI TNFα golimumab efficacy tolerability immunogenicity methotrexate posology titration oral route subcutaneous route bioavailability effectiveness periodontitis periodontal disease anti-citrullinated protein autoantibodies rheumatoid factor smoking medication Porphyromonas gingivalis Rheumatoid arthritis matrix metalloproteinase 3 infliximab pharmacogenomics anti-TNF personalized medicine baricitinib disease-modifying antirheumatic drugs pain perception outcomes research patient perspective Rheumatoid Arthritis therapy DMARD MTX Tumor Necrosis Factor-Alpha Inhibitors ankylosing spondylitis biosimilar switching synovial fibroblasts cytokine osteoclast herbal medicine methylation next-generation sequencing recovery of function fatigue productivity tofacitinib oral Th1.17 IL-17A IFN-γ, CD73 adenosine psoriatic arthritis regulation pseudoerosions hand foot ultrasonography radiography computed tomography magnetic resonance imaging |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Rheumatoid Arthritis Therapy Reappraisal |
| Record Nr. | UNINA-9910557286503321 |
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Müller Rüdiger
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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