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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (528 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
melanoma
invasion WNT5A MARCKS phosphorylation MANS peptide nanoparticles cell therapy tumor microenvironment sex/gender sex-hormones immunity microRNAs immunotherapy BRAF-mutant melanoma BRAF inhibitor mechanism of action targeted therapy tumour microenvironment plasmacytoid dendritic cells lactate dehydrogenase TLR interferon CXCL10 TPC2 HIPPO SOCE metastasis essential oils angiogenesis apoptosis uveal melanoma (UM) metastatic uveal melanoma (mUM) prognostication adjuvant therapy metastatic therapy metastatic dormancy liver-directed-therapies targeted-therapy combined therapy protein tyrosine phosphatase PTPs inhibitors melanoma immune infiltrate BRAF inhibitors microenvironment resistance therapy therapeutic resistance exosomes extracellular vesicles diagnosis prognosis ctDNA liquid biopsy prediction patient stratification BRAF arthralgia rheumatoid arthritis carbonic anhydrase hedgehog cyclopamine small molecules acetazolamide motility metalloproteinases FAK cancer mucosal melanoma nivolumab pembrolizumab ipilimumab radiotherapy cholinergic system acetylcholine muscarinic receptors nicotinic receptors melanoma metastasis ShcD adaptor protein amoeboid motility Rac1 DOCK4 melanoma PDX target therapy cancer stem cells slow cycling phenotype drug resistance OXPHOS lipid metabolism cancer associated fibroblast melanomagenesis biomarkers checkpoint inhibitor PD-1 melanoma markers cytokines machine learning Support Vector Machine principal component analysis BCL2L10 STAT3 cytotoxicity survival ABT-737 Bcl-2 family ML258 HuR MITF metastases siRNA |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Diagnosis and Therapy of Neuroendocrine Neoplasms
| Advances in Diagnosis and Therapy of Neuroendocrine Neoplasms |
| Autore | Segelov Eva |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (144 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
small bowel neuroendocrine tumours
pancreatic neuroendocrine tumours liver metastases midgut meta-analysis neuroendocrine tumors carcinoid heart disease carcinoid syndrome somatostatin analogues metastases multidisciplinary management outcome grading staging neuroendocrine neoplasms chemotherapy temozolomide metronomic treatment second-line NOTCH cancer-driven genes mutational mechanism germline mutations small cell lung carcinoma pancreatic NET small bowel NET medullary thyroid carcinoma malignant castration-resistant prostatic cells quality performance indicators QPIs cancer care neuroendocrine tumour NETs modified Delphi CommNETs pancreatic neuroendocrine neoplasms neuroendocrine tumor long-term functional outcomes pancreatectomy diabetes mellitus pancreatic exocrine insufficiency body mass index parenchyma-sparing surgery neuroendocrine tumours curative surgery resection follow-up guidelines relapse recurrence risk factor mixed non-neuroendocrine neuroendocrine neoplasms MiNENs mixed adeno-neuroendocrine carcinoma MANEC 2017 WHO classification 2019 WHO classification |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557692903321 |
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Segelov Eva
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Redox-Active Molecules as Therapeutic Agents
| Redox-Active Molecules as Therapeutic Agents |
| Autore | Fernandes Ana Sofia |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (266 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
non-small cell lung cancer
cisplatin apurinic/apyrimidinic endonuclease 1 E3330 cytotoxicity apoptosis migration invasion oxidative stress sildenafil DNA damage systemic sclerosis bioactivity-based assays cyanidin metabolomics Rubus genus (poly)phenols yeast-based discovery platform withanolide breast cancer mitochondrial reactive oxygen species peroxiredoxin 3 pro-oxidant therapy thiostrepton GSH Cysteamine N-acetyl cysteine KEAP1 NRF2 ATF4 adipose-derived mesenchymal stem cell amniotic membrane-derived mesenchymal stem cell antioxidants assisted reproductive technology conditioned medium embryo in vitro culture in vitro fertilization BAPN cell invasion EMT lysyl-oxidase lysyl-oxidase like 2 metastases inhibitors doxorubicin chemoresistance redox signaling nuclear factor erythroid 2-related factor 2 (Nrf2) cancer therapy hydrogen sulfide reactive oxygen species H2S donors cardiorenal syndrome thiosulfate selenium-enriched Enterococcus faecium selenium-enriched Streptococcus thermophilus antioxidant capacity glutathione reductase glutathione peroxidase CD IGS rats lactic acid bacteria verbascoside hypercholesterolemia prostate cancer curcumin carnosic acid cell cycle OxPhos SGK1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213403321 |
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Fernandes Ana Sofia
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of MicroRNA in Cancer Development and Treatment
| Role of MicroRNA in Cancer Development and Treatment |
| Autore | Pulliero Alessandra |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (280 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
breast cancer
miRNAs liquid biopsy angiogenesis biomarkers early diagnosis air pollution biomarker exposure human lung cancer miRNA carcinogenesis microRNA asbestos exposure oral squamous cell carcinoma diagnosis prognosis saliva neuroblastoma MYCN amplification metastases chemoresistance public health genomics genetic polymorphisms epigenetic modulations genetic and microbiome markers health technology assessment early disease prevention nonsmokers lung cancer environmental risk factors oncogenes mutations glioblastoma microRNAs cancer qPCR cancer stem cells plasticizers in vitro study PRISMA no-smokers lung cancer DNA adducts mesothelioma extracellular vesicles miR-625 fluoro-edenite asbestos malignant mesothelioma cancer prevention microbiota epigenetics environmental pollutants cutaneous tissues ozone exposure |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576878603321 |
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Pulliero Alessandra
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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