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Biomimetic Radical Chemistry and Applications 2021
| Biomimetic Radical Chemistry and Applications 2021 |
| Autore | Chatgilialoglu Chryssostomos |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (244 p.) |
| Soggetto topico |
Research & information: general
Chemistry Inorganic chemistry |
| Soggetto non controllato |
guanine
guanyl radical tautomerism guanine radical cation oligonucleotides DNA G-quadruplex time-resolved spectroscopies reactive oxygen species (ROS) oxidation catalase mimics peroxide diiron-peroxo complexes structure/activity kinetic studies biomimetic chemistry cysteine ketone reduction free radicals pulse radiolysis kinetics DNA oxidation DNA hole transfer molecular dynamics quantum dynamics electron transfer charge transfer quantum coherence chemiluminescence reaction mechanisms singlet oxygen reactive oxygen species light emission crosslink dimerization protein oxidation radicals di-tyrosine di-tryptophan disulfides thiols aggregation proteomics mass spectrometry collagen riboflavin hyaluronic acid EPR spectroscopy keratoconus STEM DNA biosensor chemical nucleases DNA-drug interaction copper complexes metallodrugs MEP pathway antibiotics IspH LytB [4Fe-4S] cluster reductive dehydroxylation bioorganometallic intermediate inhibitors methionine neighboring group effect hydroxyl radical triplet state of carboxybenzophenone one-electron oxidants laser flash photolysis peptides proteins |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576882903321 |
Chatgilialoglu Chryssostomos
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers
| Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers |
| Autore | Kutner Andrzej |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (450 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
alpha-ketoglutarate
cell cycle apoptosis JNK cell migration cell invasion TGF-β VEGF glycoconjugates methotrexate cancer treatment glucose metabolism drug design and discovery anticancer drugs targeted therapy Warburg effect antidepressants pyrido[1,2-c]pyrimidines dual 5-HT1A/SERT activity drug design anticancer activity lung cancer resveratrol PRI-2191 vitamin D active substance delivery systems biomedical hydrogels active substance-controlled release genistein hydrogels for cosmetology hydrogels for dermatology transdermal active substance delivery systems histone deacetylase (HDAC) depression biomarker anti-depressant therapy human DNA topoisomerase cancer drug molecular docking synthesis fluorine vitamin D3 metabolite A-ring CD-ring side-chain nanoparticles molecular modeling oxidation mechanisms electrochemistry MALDI spectroscopic data cytotoxic study self-assembled monolayer gold electrode multimodal activity calcium-sensing receptor enantiomer calcimimetic calcilytic colon cancer stereospecificity HT-29 IL-8 inflammation cyclooxygenase 1,2,4-triazole pyridazinone SAR anti-inflammatory activity antioxidant activity ADME anticancer drug antimicrobial peptide (AMP) dermaseptin frog skin peptides LHRH prostate cancer Phyllomedusa bicolor therapeutic peptides copper (II) complexes thiourea cytotoxic activity proteome analysis antimicrobial activity major latex protein Chelidonium majus greater celandine defense-related proteins alkaloids cancer cells vitamin D receptor split luciferase-based biosensor CYP24A1-dependent metabolism CYP27B1 rickets genome editing vitamin D biology and action transcription ChIP-chip analysis distal enhancers histone H3 acetylation RNA polymerase II analogue actions at genes vitamin D hormone (1,25(OH)2D3) latex antiviral proteins antimicrobial compounds cytotoxicity drug discovery CRISPR/Cas9 tetrahydro-β-carbolines Plasmodium falciparum (P. falciparum) antimalarial antiparasitic agents hemolysis vitamin D analogs 25 vitamin D 24-hydroxylase CYP24A1 proliferation high-grade serous ovarian cancer cells gold Au(III) complex colorectal cancer organometallic cancer therapy metallodrugs |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585938903321 |
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Kutner Andrzej
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sample Preparation in Metabolomics
| Sample Preparation in Metabolomics |
| Autore | Kuligowski Julia |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (208 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
metabolomics
sample preparation hydrophilic interaction liquid chromatography ion mobility spectrometry high resolution mass spectrometry design of experiments AMOPLS metabonomics metabolic profiling NMR nuclear magnetic resonance spectroscopy cell line human cell line MiaPaCa-2 Panc-1 AsPC-1 extracellular vesicles exosomes microvesicles biomarkers diagnostics metabolic pathways plant metabolomics forestry trees mass spectrometry metabolite extraction GC-MS LC-MS metadata standardization databases multicellular tumor spheroids metallodrugs oxaliplatin KP1339 method development IT-139 20% FCS harvesting extraction metabolites normalization electromembrane extraction cardiovascular disease multi-segment injection capillary electrophoresis–mass spectrometry liquid chromatography–mass spectrometry plant natural products drug discovery liquid chromatography gas chromatography human milk metabolome sampling liquid chromatography–mass spectrometry (LC-MS) nuclear magnetic resonance (NMR) gas chromatography–mass spectrometry (GC-MS) capillary electrophoresis—mass spectrometry (CE-MS) high-resolution magic angle spinning microscopic samples lipidomics LC-MS/MS human plasma |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557141203321 |
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Kuligowski Julia
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Unconventional Anticancer Metallodrugs and Strategies to Improve their Pharmacological Profile
| Unconventional Anticancer Metallodrugs and Strategies to Improve their Pharmacological Profile |
| Autore | Contel Maria |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto non controllato |
?-? stacking
encapsulation oxindolimine-metal complexes cyclodextrin platinum iodido complexes distribution coefficient antiproliferative activity anticancer agents nanotubes ruthenium platinum Log kw nanoparticles drug discovery metal complex metallodrugs isatin-derived ligands anticancer drug upconverting nanoparticles pyridine benzimidazole dendrimers liposomes thiophene angiogenesis micelles HSA oxidation platinum(IV) imaging chromatographic lipophilicity parameter amidophosphine copper and iron chelators in cancer Log P biomacromolecules bones DNA cleavage stopped-flow spectroscopy silver phosphonates transmetalation metallomics MRI fluorescence quenching partition coefficient gold fingers anticancer HSA binding gold ?0 targeting metastasis DNA interaction antimigration cytotoxicity HPLC ruthenium complexes zinc finger proteins Gold(III) complexes aquaporins antiproliferative protein-DNA recognition photoactivation lipophilicity cancer 1-methylcytosine PET |
| ISBN | 3-03921-316-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367755103321 |
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Contel Maria
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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