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Cancer Metabolism: Molecular Targeting and Implications for Therapy
| Cancer Metabolism: Molecular Targeting and Implications for Therapy |
| Autore | Shanmugasundaram Ganapathy-Kanniappan |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 online resource (114 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
Cancer Metabolism
epigenetic regulation glycolysis immunotherapy metabolic reprogramming metastasis Tumor microenvironment Warburg effect |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cancer Metabolism |
| Record Nr. | UNINA-9910688412403321 |
Shanmugasundaram Ganapathy-Kanniappan
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Curcumin in Health and Disease / Beatrice Bachmeier
| Curcumin in Health and Disease / Beatrice Bachmeier |
| Autore | Bachmeier Beatrice |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto topico | Chemistry |
| Soggetto non controllato |
minerals
cancer treatment chitosan neurodegeneration antioxidant activity senescence tumor proliferation nanoparticles antimicrobial agents oxidative metabolites drug discovery Akt/mTOR signaling micronutrients ulcerative colitis transmission electron microscopy metabolic reprogramming curcumin death receptor chaperone-mediated autophagy wound healing brain ischemia autophagy Alzheimer's disease genes transthyretin inflammatory bowel disease cellular pathway centrifugal partition chromatography nutrition amyloid Curcuma longa protein aggregation supportive care IL-17 senolytics complementary medicine macronutrients structure activity relationship gastroprotection Zingiberaceae anti-inflamation TLC bioautography microbiota glioblastoma multiforme amyloidosis SHMT2 antioxidants silica apoptosis reflux esophagitis gastric ulcer TLC-MS anti-cancer anticancer ImageJ anti-tumor delivery system wound Helicobacter pylori direct protein binding protein misfolding tumor growth diet Crohn's disease hydrostatic counter-current chromatography ageing renal cell cancer gastric cancer amino-acids STAT3 mechanism of action inflamm-aging mitophagy necrotizing enterocolitis cell cycling vitamins turmeric tuber cancer tau protein |
| ISBN |
9783039214501
3039214500 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367753703321 |
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Bachmeier Beatrice
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Emerging Role of Lipids in Metabolism and Disease
| Emerging Role of Lipids in Metabolism and Disease |
| Autore | Pallottini Valentina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (308 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
acid sphingomyelinase
adiponectin adipose tissue angiogenesis atherosclerosis ATM autotaxin BDNF BET proteins brain breast cancer breast reconstruction cardiovascular disease cell proliferation cell signaling cholesterol Cholesterol chronic inflammation diabetes mellitus DNA damage response double strand breaks eicosanoids endothelial cell epicardial fat thickness epigenetics epinephrine fatty acid Fatty acids female frontal cortex G-protein coupled receptors gender glyceride haptoglobin high-cholesterol diet high-density lipoprotein high-sensitivity c-reactive protein hippocampus HMGCR hyperglycemia ionizing radiation ischemia ischemic stroke JQ1 LDLr leptin lipid lipid droplets lipid mediators Lipid mediators lipid metabolism lipid metabolism diseases lipid storage diseases Lipids lipocalin lipolysis lipophagy Lipophagy lipoproteins liver lysocardiolipin acyltransferase lysophosphatidic acid metabolic reprogramming metabolic stress metabolism mTORC1 mutations neutral sphingomyelinase nuclear sphingolipids oral drug absorption oxidative stress oxidized phospholipids p53 pathology phosphatidylinositol 4,5-bisphosphate phospholipase A2 (PLA2) phospholipase C phospholipase D phospholipid polyunsaturated fatty acids prodrug prostaglandins pulmonary fibrosis radiation SOD sphingolipids Sphingolipids sphingomyelin metabolism sphingosine kinase 1 sphingosine-1-phosphate SREBP steroid synaptic proteins TFEB TMEM97 visceral fat thickness |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557800303321 |
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Pallottini Valentina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges
| Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges |
| Autore | Gabazza Esteban C |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (348 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
acute lung injury
anaplastic lymphoma kinase angiogenesis antitumor efficacy apoptosis bleomycin breast cancer butylidenephthalide cancer cancer-associated fibroblasts cancer-associated fibroblasts (CAFs) carcinogenesis cirrhosis clinical symptoms common pathways crizotinib cystic formation cytokine cytokines DHA diagnosis EMT Erk1/2 extracellular matrix fibrosis genetic instability GPR120 GPR40 growth factor HBV HCV hepatic stellate cells hepatic stellate cells (HSCs) hepatocellular carcinoma hepatocellular carcinoma (HCC) hepatocytes heterogeneity Hippo pathway idiopathic pulmonary fibrosis idiopathic pulmonary fibrosis (IPF) immunohistochemistry inflammation interstitial fluid pressure leiomyoma leiomyosarcoma lipopolysaccharide lncRNA lung cancer lung cancer (LC) marker mechanotransduction metabolic reprogramming metastasis miRNA myometrium n/a nanoparticles non-alcoholic steatohepatitis non-small cell lung cancer (NSCLC) omega-3 fatty acid pathogenesis pathology pathophysiology protein S pulmonary fibrosis reactive oxygen species regeneration renal injury signal pathway SMAD smooth muscle tumor of uncertain malignant potential SOX2 SREBP-1 targeted therapy TAZ TGF-? therapy transforming growth factor-? tumor tumor microenvironment tumor necrosis factor ? tumor stiffness type I collagen uterine fibroid Wnt YAP |
| ISBN | 3-03921-707-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Links between Fibrogenesis and Cancer |
| Record Nr. | UNINA-9910367745903321 |
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Gabazza Esteban C
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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mTOR in Human Diseases / Olivier Dormond
| mTOR in Human Diseases / Olivier Dormond |
| Autore | Dormond Olivier |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
primary cilia
neurodegeneration nutrient sensor PI3K transcriptomics phosphorylation metabolic reprogramming autophagy Alzheimer's disease rapalogs liver angiogenesis mTOR complex MBSCs advanced biliary tract cancers Medulloblastoma epithelial to mesenchymal transition AMPK p70S6K lipid metabolism thyroid cancer sodium iodide symporter (NIS)/SLC5A5 male fertility anesthesia illumina mTOR inhibitor miRNA Hutchinson-Gilford progeria syndrome (HGPS) eIFs Emery-Dreifuss muscular dystrophy (EDMD) glucose AKT oral cavity squamous cell carcinoma (OSCC) glucose and lipid metabolism cellular signaling aging tumor microenvironment rapamycin leukemia chloral hydrate rapalogues schizophrenia T-cell acute lymphoblastic leukemia senescence lamin A/C neurotoxicity neurodevelopment inhibitor methamphetamine pulmonary fibrosis mTOR mTOR inhibitors combination therapy proteolysis fluid shear stress tumour cachexia biomarkers synapse gluconeogenesis mTOR signal pathway Sertoli cells immunosenescence miRNome protein aggregation senolytics metabolism NGS mTORC2 mTORC1 metabolic diseases IonTorrent apoptosis dopamine receptor nocodazole microenvironment everolimus acute myeloid leukemia immunotherapy spermatogenesis bone remodeling signalling targeted therapy ageing therapy NVP-BEZ235 fructose physical activity laminopathies MC3T3-E1 cells cell signaling microRNA cancer lipolysis melatonin Parkinson's disease |
| ISBN |
9783039210619
3039210610 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684303321 |
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Dormond Olivier
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Insights in the Genetics and Genomics of Adrenocortical Tumors and Pheochromocytomas
| New Insights in the Genetics and Genomics of Adrenocortical Tumors and Pheochromocytomas |
| Autore | Igaz Peter |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (272 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adaptive metabolism
adenoma adrenal adrenal gland adrenalectomy adrenocortical adrenocortical carcinoma adrenocortical tumor aldosterone aldosterone producing adenoma aldosterone-producing adenoma ALT arterial stiffness artificial intelligence ATP2B3 ATRX bioinformatic clustering biomarker biomarker prediction cancer circulating conn adenoma driver mutations drug discovery endocrine tumor syndrome environment epidemiology epigenetics fatty acid metabolism ferroptosis genetic analysis genetic testing genetics germline H295 strains hereditary hereditary cancer hyperaldosteronism in silico analysis K416-F418delinsN mutation KCNJ5 somatic mutation machine learning malignancy metabolic reprogramming metabolomics metastatic microRNA mitochondrial complex II mitotane mortality mutations n/a neonatal screening neural network next generation sequencing Next Generation Sequencing non-coding RNA NOP10 paraganglioma paragangliomas phaeochromocytoma pheochromocytoma pheochromocytomas PPARα PPGL primary aldosteronism prognostic biomarker propensity score matching pulse wave velocity redox balance pathway RNAseq screening somatic surveillance susceptibility genes telomeres TERT therapy tissue TP53 R337H transcriptomics treatment tumor microenvironment tumor suppressor genes variants Vitamin C zebrafish β-oxidation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557609003321 |
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Igaz Peter
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Treatment Strategies for Glioblastoma
| Novel Treatment Strategies for Glioblastoma |
| Autore | Stylli Stanley |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (268 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
angiopoietin (Ang)
anti-angiogenesis anticancer brain cancer brain tumor cancer stem cell cancer stem cell niche cancer stem cells cell cycle chimeric antigen receptor (CAR) T cells CK2 CRISPR/Cas9 CX-4945 de novo purine synthesis differentiation drug repurposing drug targets drug-inducible gene expression endothelial nitric oxide synthase (eNOS) GBM gene therapy glioblastoma glioblastoma (GB) glioblastoma multiforme glioma immune checkpoint inhibitors immunotherapy invadopodia invasion ion channels Mardepodect metabolic reprogramming metabolic treatment migration n/a nanomedicine nerve/glial antigen 2 new trial design newly diagnosed glioblastoma NG2 novel therapy one-carbon metabolism organoids P-bi-TAT P-m-TAT PEG personalized treatment pluripotent stem cells proliferation prolyl-oligopeptidase (POP) radiotherapy RAS recurrent glioblastoma Regorafenib renin-angiotensin system SRGAP2 stem cell targeted therapy temozolomide tetrac thyrointegrin αvβ3 TP53 transforming growth factor-β (TGF-β) triazole tetrac tumor antigens tumor microenvironment vaccine vascular endothelial growth factor (VEGF) viral vectors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557363703321 |
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Stylli Stanley
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Renal Cell Carcinoma
| Renal Cell Carcinoma |
| Autore | López José I |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (500 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
11) translocation renal cell carcinoma
ALK AMP-activated protein kinases anaplastic lymphoma kinase rearrangement aurora A biomarker cancer immunotherapy cancer-specific survival CDKN1A expression checkpoint inhibitors chromophobe renal cell carcinoma chromosomal loss chronic kidney disease circular RNAs in a clinico-genomic predictive model clear cell renal cell carcinoma clear cell Renal Cell Carcinoma collecting duct carcinoma copy number alteration copy number analysis copy number loss curcumin cytoreductive nephrectomy diagnostic and prognostic markers drug sensitivity efficacy emerging entity EMT like eosinophilic variant ESC everolimus EVI1 experimental validation of circular RNA FISH FOXO3 gene expression gene signature genetic association ghrelin glutathione metabolism glutathione transferase omega 1 glutathione transferase omega 2 glycomarkers glycoproteomics HOT hyperosmolality identification of circular RNAs IL-1? IL-2 IL13R?1 IL4R? immune checkpoint inhibitors immune infiltration immunohistochemistry immunotherapy inflammation markers integrins intratumour heterogeneity invasion JAK2 kidney kidney cancer label-free LOT metabolic reprogramming metabolome metabolome profiling metastasis metastatic ccRCC microRNA miR-133b miR-146a-5p miR-155-5p MiT family translocation renal cell carcinoma MMP-9 MMP10 molecular genetic features MTA2 mTOR mTOR inhibitors mutation N-glycomapping n/a nephrectomy new entity NK cells oncocytic renal tumor overall survival pale cell Papillary renal cell carcinoma (pRCC) patient survival PBRM1 PD-L1 pentose phosphate pathway PI3K/Akt/mTOR polybromo-1 polymorphism PPP practical approach predictive factors predictive role pro-IL-1? prognosis prognostic factors programmed death-ligand 1 proliferation proteome profiling Raf/MEK/ERK RCC recurrence free survival recurrence-free survival renal cancer renal cell renal cell cancer renal cell carcinoma review RNA sequencing sarcomatoid SMAD proteins solute carrier proteins statins survival survival prediction t(6 targeted therapy TCA cycle TCGA TFE3 TFEB TFEB-amplified renal cell carcinoma toxicity transforming growth factor beta tumor adhesion tumor microenvironment tumor migration tumor slice culture tyrosine kinase inhibitors unclassified renal cell carcinoma unclassified renal tumor uric acid urine VEGF inhibitors von Hippel-Lindau Xp11 translocation renal cell carcinoma |
| ISBN | 3-03928-639-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087003321 |
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López José I
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Metabolism in Regulating Immune Cell Fate Decisions
| Role of Metabolism in Regulating Immune Cell Fate Decisions |
| Autore | Ohradanova-Repic Anna |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (224 p.) |
| Soggetto topico |
Immunology
Medicine and Nursing |
| Soggetto non controllato |
cell fate decisions
immune cell regulation immunometabolism innate lymphoid cells metabolic reprogramming myeloid cells T cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557426303321 |
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Ohradanova-Repic Anna
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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