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Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor
| Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor |
| Autore | Holzmann Klaus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (276 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
FGFR4
FGF19 gene regulation cancer signaling anticancer FRS2 FGFR NVP-BGJ398 LY2874455 sarcoma cancer-associated fibroblasts GPER breast cancer estrogen FGFR1 FGF2 optogenetics ERK AKT receptor kinase neurite outgrowth HEK293 PC12 fibroblast growth factor receptors signaling receptor cross-talk coreceptor membrane proteins FGFR2 ERK1/2 phosphorylation serine negative feedback loop cancer prognosis HCC inhibitors FGF fibroblast growth factor autocrine signaling skin melanoma squamous and basal cell carcinoma seborrheic keratosis targeted therapy resistance structure kinase inhibitor gastric cancer monoclonal antibody small molecule FGFR2c autophagy keratinocyte MTOR JNK1 review malignant glioma brain cancer astrocytoma Sprouty proteins FGF-mediated signaling tumor suppressor tumor promoter malignant pleural mesothelioma overall survival immunohistochemistry infigratinib sensitivity FGF8 FGF18 adenocarcinoma of the esophagogastric junction neoadjuvant therapy |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Fibroblast Growth Factor Receptor |
| Record Nr. | UNINA-9910557898903321 |
Holzmann Klaus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mechanisms of ER Protein Import
| Mechanisms of ER Protein Import |
| Autore | Zimmermann Richard |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
chaperones
contact sites endoplasmic reticulum ER-SURF membrane extraction mitochondria protein targeting bimolecular luminescence complementation competition split luciferase membrane proteins protein-protein interactions Sec61 complex Sec63 synthetic peptide complementation TRAP complex ER protein translocase signal peptide protein translocation nascent peptide chain membrane insertion molecular modelling molecular dynamics simulations molecular docking signal peptidase ER translocon signal recognition particle dependent protein targeting Sec61 dependent translocation co-translational translocation inhibitor high throughput screening Sec61 Sec62 folding insertion membrane protein translocon ribosome transmembrane segment lipid droplets peroxisomes PEX3 membrane protein insertion label-free quantitative mass spectrometry differential protein abundance analysis Zellweger syndrome GET protein transport SND SRP EMC positive-inside rule hydrophobicity transmembrane helix signal recognition particle nascent polypeptide-associated complex fidelity cyclotriazadisulfonamide ER quality control DNAJC3 preprotein Sec61 translocon ribosome stalling signal sequence Sec61 translocase NAC |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576886203321 |
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Zimmermann Richard
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Tight Junction and Its Proteins : More Than Just a Barrier
| The Tight Junction and Its Proteins : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (432 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tissue barrier
tight junction claudins tricellulin tight junctions organ preservation intestine transplantation ischemia intestinal mucosa lung epithelia interleukin 13 UBE2Z ubiquitin osmolality hydrostatic pressure cancer sensor tricellular tight junctions endometrial cancer epithelial barrier dysfunction Claudin-7 permeability WNK4 epithelial sodium channel (ENaC), collecting duct cells claudin-1 hydrogen peroxide phosphorylation claudin angulin drug development angubindin-1 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin antibody Mz-ChA-1 cells biliary epithelial cells phosphatidylcholine mucus paracellular transport atopic dermatitis cytokines STAT3 ZO-2 cholestasis gene transcription hypertrophy tumor suppressor NLS NES CaSR RhoA barrier function paracellular permeability antidiuretic hormone Claudin-14 CLDN14 hearing loss vestibular function cochlear implantation Hepatitis C Virus viral entry epidermal barrier reconstructed human epidermis claudin targeting Campylobacter jejuni curcumin apoptosis co-culture mouse colon TNF NFκB lipolysis-stimulated lipoprotein receptor (LSR) epithelial barrier cell–cell contact caspase kidney stones ion reabsorption quercetin brain barriers blood-brain barrier neurovascular unit blood-cerebrospinal fluid barrier arachnoid barrier glia limitans adherens junctions paracellular sodium transport thick ascending limb nephropathy HELIX syndrome hypokalemia hypermagnesemia anhidrosis gland dysfunction aging blood–brain barrier mutations kidney liver skin human mice disease in silico drug discovery membrane proteins protein interactions molecular dynamics antibiotic-associated hemorrhagic colitis Klebsiella oxytoca tight junction assembly monocytes celiac disease claudin-2 epithelium inflammation fibrosis proliferation migration tricellular tight junction paracellular water transport tight epithelium MDCK C7 cells cell growth endothelia adherens junction apical junctional complex AMP-activated protein kinase (AMPK) paracellular barrier protein structure protein domain occludin junctional adhesion molecule zonula occludens MAGUK proteins PDZ domain stem cell chemoresistance retinal pigment epithelium retinopathy barrier formation collecting duct claudin-5 neuropathic pain nerve injury dorsal root ganglion enteropathogenic E. coli (EPEC) tight junctions (TJ) polarity atypical aPKCζ transepithelial electrical resistance (TER) sorting nexin 9 (SNX9) EspF claudin 1 tumor metastasis epithelial to mesenchymal transition cerebral cavernous malformation endothelial barrier Rho ROCK MEKK3 ion transport ion channel super-resolution microscopy structured illumination microscopy stimulated emission depletion single molecule localization microscopy Claudin blood-biliary barrier chronic liver disease hepatocellular carcinoma cholangiocellular carcinoma NISCH syndrome repair NHE2 ClC-2 inflammatory bowel disease mucosal immunology ZO-1 actomyosin aquaporin drinking rate epithelial fluid transport enterocyte osmoregulation paracellular proximal tubule calcium permeability claudin-12 paracellular channels and barriers cell polarity pathogens immune cells environmental sensors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910557404603321 |
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Fromm Michael
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier
| The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (412 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tissue barrier
tight junction claudins tricellulin tight junctions organ preservation intestine transplantation ischemia intestinal mucosa lung epithelia interleukin 13 UBE2Z ubiquitin osmolality hydrostatic pressure cancer sensor tricellular tight junctions endometrial cancer epithelial barrier dysfunction Claudin-7 permeability WNK4 epithelial sodium channel (ENaC), collecting duct cells claudin-1 hydrogen peroxide phosphorylation claudin angulin drug development angubindin-1 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin antibody Mz-ChA-1 cells biliary epithelial cells phosphatidylcholine mucus paracellular transport atopic dermatitis cytokines STAT3 ZO-2 cholestasis gene transcription hypertrophy tumor suppressor NLS NES CaSR RhoA barrier function paracellular permeability antidiuretic hormone Claudin-14 CLDN14 hearing loss vestibular function cochlear implantation Hepatitis C Virus viral entry epidermal barrier reconstructed human epidermis claudin targeting Campylobacter jejuni curcumin apoptosis co-culture mouse colon TNF NFκB lipolysis-stimulated lipoprotein receptor (LSR) epithelial barrier cell–cell contact caspase kidney stones ion reabsorption quercetin brain barriers blood-brain barrier neurovascular unit blood-cerebrospinal fluid barrier arachnoid barrier glia limitans adherens junctions paracellular sodium transport thick ascending limb nephropathy HELIX syndrome hypokalemia hypermagnesemia anhidrosis gland dysfunction aging blood–brain barrier mutations kidney liver skin human mice disease in silico drug discovery membrane proteins protein interactions molecular dynamics antibiotic-associated hemorrhagic colitis Klebsiella oxytoca tight junction assembly monocytes celiac disease claudin-2 epithelium inflammation fibrosis proliferation migration tricellular tight junction paracellular water transport tight epithelium MDCK C7 cells cell growth endothelia adherens junction apical junctional complex AMP-activated protein kinase (AMPK) paracellular barrier protein structure protein domain occludin junctional adhesion molecule zonula occludens MAGUK proteins PDZ domain stem cell chemoresistance retinal pigment epithelium retinopathy barrier formation collecting duct claudin-5 neuropathic pain nerve injury dorsal root ganglion enteropathogenic E. coli (EPEC) tight junctions (TJ) polarity atypical aPKCζ transepithelial electrical resistance (TER) sorting nexin 9 (SNX9) EspF claudin 1 tumor metastasis epithelial to mesenchymal transition cerebral cavernous malformation endothelial barrier Rho ROCK MEKK3 ion transport ion channel super-resolution microscopy structured illumination microscopy stimulated emission depletion single molecule localization microscopy Claudin blood-biliary barrier chronic liver disease hepatocellular carcinoma cholangiocellular carcinoma NISCH syndrome repair NHE2 ClC-2 inflammatory bowel disease mucosal immunology ZO-1 actomyosin aquaporin drinking rate epithelial fluid transport enterocyte osmoregulation paracellular proximal tubule calcium permeability claudin-12 paracellular channels and barriers cell polarity pathogens immune cells environmental sensors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910674057303321 |
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Fromm Michael
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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