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ABC Transporters in Human Diseases
| ABC Transporters in Human Diseases |
| Autore | Falguières Thomas |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (494 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
5' untranslated region
AAV ABC ABC (ATP-binding cassette) transporters ABC transporter ABC transporters ABCA subfamily ABCA7 ABCB1 ABCB11 ABCB4 ABCC2 ABCC6 ABCG2 ABCG2 genotype ABCG5 ABCG5/G8 ABCG8 adrenoleukodystrophy Alzheimer's disease amyloid-beta anticancer antifungal resistance atherosclerosis ATP-binding cassette transporter ATP-binding cassette transporter A1 (ABCA1) Aβ peptides BCRP beta-amyloid bile salts bile secretion bioinformatics blood-brain barrier breast cancer BRIC BSEP calcification cAMP cancer cellular ATP efflux chaperones cholesterol cholesterol homeostasis cis-acting elements clinico-genetic analysis competitive allele-specific PCR disease-free survival drug action drug transport dyslipidemia early-onset gout erlotinib ethnic specificity fatty acids functional divergence gall stone gene therapy generalized arterial calcification of infancy genetic variations gout HDL-C homology modeling hyperuricemia intracellular traffic intrahepatic cholestasis invasion MDR3 mechanism mechanism of action membrane protein microparticles migration molecular partners MRP1 MRP4 multidrug resistance multidrug transporter mutagenesis mutations n/a neuron next-generation sequencing NT5E P-glycoprotein peroxisome PET PFIC PFIC2 phagocytosis phosphatidylcholine phytosterol polar relay polymorphisms precision medicine proliferation pseudoxanthoma elasticum Pseudoxanthoma elasticum (PXE) pyrophosphate RAB GTPase rare variant regulatory extension regulatory insertion reverse cholesterol transport Roma serum uric acid single nucleotide polymorphism sitosterolemia SK-N-SH SNP SUA-lowering therapy substrate-binding site tariquidar taxol therapies therapy response TNAP trafficking transport transporter type 2 diabetes urate urate transporter uric acid xenosterol yeast |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674029103321 |
Falguières Thomas
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0
| Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0 |
| Autore | Dansette Patrick M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (286 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
20-HETE
active site access channels Antibiotics arachidonic acid azole drugs Bacillus Bietti's crystalline dystrophy biosynthetic gene clusters cavities boundaries circulatory CYPs comparative analysis cryptococcus cryptococcus neoformans crystal structure Cyanobacteria CYP diversity analysis CYP128A1 CYP139A1 CYP2C8 CYP3A4 CYP4 genes CYP450 CYP51 Cytochrome b5 (CYB5) cytochrome P450 cytochrome P450 monooxygenase cytochrome P450 monooxygenases cytochrome P450 monooxygenenases cytochrome P450 reductase cytochromes P450 cytochromes P450 monooxygenases drug metabolism electron transfer electron-transfer (ET) enzyme substrate specificity exosomes extracellular vesicles extrahepatic tissues fatty acid fungal pathogens gene-cluster diversity percentage genetic polymorphisms genome data mining genome data-mining host metabolism human pathogens isoform lamellar ichthyosis mathematical formula mechanism-based inhibitor membrane protein menaquinone metabolism microsomal cytochrome P450 (CYP) minimal cost paths molecular dynamic simulations molecular dynamics simulation molecular functionality mutagenesis Mycobacterium Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv NADPH-cytochrome P450 reductase (CPR) non-ribosomal peptides P450 blooming P450 diversity percentage P450 profiling paclitaxel phylogenetic analysis plasma polyketides polymorphisms precision Cardio-Oncology precision medicine protein dynamics protein-membrane interactions protein-protein interaction reactive oxygen species RNA interference secondary metabolites SNPs Sogatella furcifera Streptomyces sulfoxaflor systems medicine terpenes transcriptome tremellomycetes trichosporon tuberculosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cytochromes P450 |
| Record Nr. | UNINA-9910557761103321 |
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Dansette Patrick M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Enzymatic Bioelectrocatalysis
| Enzymatic Bioelectrocatalysis |
| Autore | Lojou Elisabeth |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (176 p.) |
| Soggetto topico |
Industrial chemistry and chemical engineering
Technology: general issues |
| Soggetto non controllato |
biocatalytic reactors
bioelectrocatalysis bioelectrocatalysts bioelectrochemistry bioelectrosynthesis biofuel cells carbon nanomaterials catalysis direct electron transfer electrochemical reactors electrochemistry electrode modification electron transfer enzyme gold electrode hybrid vesicles liposomes membrane protein metallic nanostructures metalloenzyme microbial electrosynthesis n/a nanostructured electrodes orientation oxidoreductase oxidoreductases photo-bioelectrocatalysis photosynthesis protein engineering self-assembled molecular monolayers stability surface modification |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566458303321 |
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Lojou Elisabeth
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mechanisms of ER Protein Import
| Mechanisms of ER Protein Import |
| Autore | Zimmermann Richard |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (258 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
bimolecular luminescence complementation
chaperones co-translational translocation competition contact sites cyclotriazadisulfonamide differential protein abundance analysis DNAJC3 EMC endoplasmic reticulum ER protein translocase ER quality control ER translocon ER-SURF fidelity folding GET high throughput screening hydrophobicity inhibitor insertion label-free quantitative mass spectrometry lipid droplets membrane extraction membrane insertion membrane protein membrane protein insertion membrane proteins mitochondria molecular docking molecular dynamics simulations molecular modelling n/a NAC nascent peptide chain nascent polypeptide-associated complex peroxisomes PEX3 positive-inside rule preprotein protein targeting protein translocation protein transport protein-protein interactions ribosome ribosome stalling Sec61 Sec61 complex Sec61 dependent translocation Sec61 translocase Sec61 translocon Sec62 Sec63 signal peptidase signal peptide signal recognition particle signal recognition particle dependent protein targeting signal sequence SND split luciferase SRP synthetic peptide complementation translocon transmembrane helix transmembrane segment TRAP complex Zellweger syndrome |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576886203321 |
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Zimmermann Richard
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances in Antibody Therapeutics
| Recent Advances in Antibody Therapeutics |
| Autore | Heo Yong-Seok |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (238 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
affinity maturation
agonist antibody anti-angiogenesis anti-cancer antibody antibodies antibody antibody engineering antibody therapeutics antibody therapy antibody-drug conjugates antigen asthma atherosclerosis binding assays bioassays biochemical and physicochemical properties biomarker biophysical properties bispecific antibodies bladder cancer blood-brain barrier brain shuttle C2_2E12 cell fate combinatorial antibody library computational methods cost-effectiveness cytomegalovirus delta-like ligand disposition enfortumab vedotin erdafitinib Fc binding G protein-coupled receptor HPV cancer therapy HPV oncoproteins HPV-associated cancer Human papillomaviruses immune checkpoint inhibitors inflammation interleukin 33 intracellular antibodies irinotecan mechanisms of action membrane protein molecular Trojan horse monoclonal antibody n/a nanobody paclitaxel peptide/major histocompatibility complex class I complex phage display pharmacokinetics potency assays receptor-binding domain receptor-mediated transcytosis recombinant antibodies refractory asthma research cell bank sacituzumab govitecan SARS-CoV-2 scFv single-chain antibody fragment spike protein ST2 receptor T-cell-receptor-like antibody therapeutic antibody transferrin VEGF yeast surface display |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580204803321 |
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Heo Yong-Seok
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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