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ABC Transporters in Human Diseases
| ABC Transporters in Human Diseases |
| Autore | Falguières Thomas |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (494 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
ABC transporters
drug action regulatory extension regulatory insertion mechanism of action MRP1 MRP4 breast cancer proliferation migration invasion cAMP ABCG2 ABCB1 blood-brain barrier PET Alzheimer's disease beta-amyloid tariquidar erlotinib ABCG5 ABCG8 ATP-binding cassette transporter cholesterol polar relay sitosterolemia 5' untranslated region cis-acting elements ABCA subfamily bioinformatics ABC transporter therapy response disease-free survival next-generation sequencing competitive allele-specific PCR P-glycoprotein amyloid-beta neuron SK-N-SH gene therapy AAV PFIC BSEP ABCB11 bile salts intrahepatic cholestasis chaperones PFIC2 BRIC ATP-binding cassette transporter A1 (ABCA1) cholesterol homeostasis reverse cholesterol transport HDL-C dyslipidemia type 2 diabetes microparticles ABCG2 genotype clinico-genetic analysis ethnic specificity genetic variations precision medicine rare variant Roma serum uric acid SUA-lowering therapy urate transporter bile secretion ABCB4 ABCC2 ABCG5/G8 molecular partners phytosterol xenosterol atherosclerosis gall stone ABC transporter ABC (ATP-binding cassette) transporters multidrug resistance transport trafficking urate mutations polymorphisms ABCC6 TNAP NT5E Pseudoxanthoma elasticum (PXE) cancer membrane protein functional divergence calcification pseudoxanthoma elasticum generalized arterial calcification of infancy pyrophosphate therapies ABCA7 phagocytosis Aβ peptides yeast multidrug transporter anticancer antifungal resistance mechanism peroxisome adrenoleukodystrophy fatty acids gout early-onset gout hyperuricemia uric acid BCRP single nucleotide polymorphism SNP homology modeling substrate-binding site cellular ATP efflux mutagenesis intracellular traffic MDR3 phosphatidylcholine RAB GTPase taxol drug transport |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674029103321 |
Falguières Thomas
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (528 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
melanoma
invasion WNT5A MARCKS phosphorylation MANS peptide nanoparticles cell therapy tumor microenvironment sex/gender sex-hormones immunity microRNAs immunotherapy BRAF-mutant melanoma BRAF inhibitor mechanism of action targeted therapy tumour microenvironment plasmacytoid dendritic cells lactate dehydrogenase TLR interferon CXCL10 TPC2 HIPPO SOCE metastasis essential oils angiogenesis apoptosis uveal melanoma (UM) metastatic uveal melanoma (mUM) prognostication adjuvant therapy metastatic therapy metastatic dormancy liver-directed-therapies targeted-therapy combined therapy protein tyrosine phosphatase PTPs inhibitors melanoma immune infiltrate BRAF inhibitors microenvironment resistance therapy therapeutic resistance exosomes extracellular vesicles diagnosis prognosis ctDNA liquid biopsy prediction patient stratification BRAF arthralgia rheumatoid arthritis carbonic anhydrase hedgehog cyclopamine small molecules acetazolamide motility metalloproteinases FAK cancer mucosal melanoma nivolumab pembrolizumab ipilimumab radiotherapy cholinergic system acetylcholine muscarinic receptors nicotinic receptors melanoma metastasis ShcD adaptor protein amoeboid motility Rac1 DOCK4 melanoma PDX target therapy cancer stem cells slow cycling phenotype drug resistance OXPHOS lipid metabolism cancer associated fibroblast melanomagenesis biomarkers checkpoint inhibitor PD-1 melanoma markers cytokines machine learning Support Vector Machine principal component analysis BCL2L10 STAT3 cytotoxicity survival ABT-737 Bcl-2 family ML258 HuR MITF metastases siRNA |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
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Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anti-inflammatory Activity of Plant Polyphenols 2.0
| Anti-inflammatory Activity of Plant Polyphenols 2.0 |
| Autore | Dell'Agli Mario |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (120 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
flavonoids
inflammation p53 cancer prevention Nrf2 pathway anti-oxidant verbascoside polyphenols insulin-producing cells diabetes UPR oxidative stress ER-stress PERK anti-inflammatory mitochondria antioxidants marine algae anti-viral activity mechanism of action Antirhea borbonica kidney fibrosis caffeic acid antioxidant enzymes DESI-imaging curcumin glioblastoma cells radiation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576880903321 |
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Dell'Agli Mario
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Curcumin in Health and Disease
| Curcumin in Health and Disease |
| Autore | Bachmeier Beatrice |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto non controllato |
minerals
cancer treatment chitosan neurodegeneration antioxidant activity senescence tumor proliferation nanoparticles antimicrobial agents oxidative metabolites drug discovery Akt/mTOR signaling micronutrients ulcerative colitis transmission electron microscopy metabolic reprogramming curcumin death receptor chaperone-mediated autophagy wound healing brain ischemia autophagy Alzheimer's disease genes transthyretin inflammatory bowel disease cellular pathway centrifugal partition chromatography nutrition amyloid Curcuma longa protein aggregation supportive care IL-17 senolytics complementary medicine macronutrients structure activity relationship gastroprotection Zingiberaceae anti-inflamation TLC bioautography microbiota glioblastoma multiforme amyloidosis SHMT2 antioxidants silica apoptosis reflux esophagitis gastric ulcer TLC-MS anti-cancer anticancer ImageJ anti-tumor delivery system wound Helicobacter pylori direct protein binding protein misfolding tumor growth diet Crohn's disease hydrostatic counter-current chromatography ageing renal cell cancer gastric cancer amino-acids STAT3 mechanism of action inflamm-aging mitophagy necrotizing enterocolitis cell cycling vitamins turmeric tuber cancer tau protein |
| ISBN | 3-03921-450-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367753703321 |
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Bachmeier Beatrice
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Herbicide Resistance in Plants
| Herbicide Resistance in Plants |
| Autore | Beckie Hugh J |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
best management practices
crop competition herbicide resistance integrated weed management precision weed management site-specific weed management Citrus latifolia hairy beggarticks junglerice tropical sprangletop corn herbicide resistance trait maize soybean amino acid biosynthesis lipid biosynthesis mechanism of action plastoquinone biosynthesis pyrimidine biosynthesis target site weeds genomics plant genome assembly non-target site resistance population genomics genome scans population genetics non-target metabolomics GC-MS priming hormesis D1 protein acetolactate synthase tubulin ACCase EPSPS phytoene desaturase PPO glutamine synthetase auxin Non-target-site resistance herbicide mode of action co-existence environmental conditions resistance mutation fitness benefit fitness cost resistance management weed genomics herbicide resistance database herbicide resistance diagnostics precision herbicide resistance management functional genomics weed biology weed evolution integrated pest management sensitivity line ryegrass herbicide dose dose-response non-target-site resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557631903321 |
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Beckie Hugh J
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Integrative Multi-Omics in Biomedical Research
| Integrative Multi-Omics in Biomedical Research |
| Autore | Gerner Christopher |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (178 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
target identification
target validation label-free method for drugs anti-angiogenesis mechanism of action receptor tyrosine kinases curcumin natural products lipid lipidomics cardiac metaplasia Barrett's esophagus esophageal adenocarcinoma microbiota DNA sensing IFI16 cGAS innate immunity protein interactions virus-host interactions post-translational modifications mass spectrometry proteomics transcriptomics multi-omics multi-omics analysis study design bioinformatics machine learning analysis flow metabolomics planned myocardial infarction (PMI) myocardial infarction (MI) exercise heart cheminformatics batch variations eicosanoids fetal calf serum peroxisomes host-pathogen interactions secretome macrophages acute myeloid leukemia HL-60 cell line ATRA induced differentiation transcriptome proteome transcription factors key molecules regulatory pathway modelling SRM endometriosis inflammation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557769003321 |
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Gerner Christopher
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Isolation and Identification of Bioactive Secondary Metabolites
| Isolation and Identification of Bioactive Secondary Metabolites |
| Autore | Seca Ana Maria Loureiro da |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (272 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
coumarins
Lycium metabolomic HPLC-MS orbitrap secondary metabolites endemic plants olive leaves supercritical fluid extraction antioxidants hyperuricemia plant-based functional food xanthine oxidase adenosine deaminase uric acid transporter bioactive compound Piper pseudoarboreum bioassay-guided fractionation leishmanicidal activity alkamides (E)-piplartine Wedelia chinensis organic farming phytotoxic substances vanillic acid gallic acid Origanum subspecies morphological traits glandular trichomes essential oil composition rosmarinic acid sensory evaluation colored potato tubers total phenols anthocyanins saccharides nutrition microelements plants fungi food supplements cardiovascular diseases neurodegenerative diseases Alzheimer's disease metabolic syndrome apocarotenoid caffeic acid derivative flavonoid Lactuca sativa lignan megastigmane sesquiterpene lactone 1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid black chokeberry anthocyanin simulated moving bed antioxidant activity neuroprotection Artemisia clinical trials health effects adverse effects anticancer antiparasitic artemisinin santonin achillin tehranolide Aglaomorpha quercifolia GC-MS profile rhizome leaves n-hexane extract fatty acids terpenoids linolenic acid hop-16-ene cardiac glycosides secondary plant metabolites natural product isolation hyrcanoside deglucohyrcanoside ouabain cymarin digitoxin anticancer activity Na+/K+-ATPase inhibitors corn salad leafy vegetables phytochemicals liquid chromatography mass spectrometry celastrol Celastraceae antimicrobial activity mechanism of action Bacillus subtilis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576883103321 |
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Seca Ana Maria Loureiro da
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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MERS-CoV
| MERS-CoV |
| Autore | Du Lanying |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto non controllato |
cell–cell fusion
hDPP4 n/a therapeutics animal models HCoV-229E Drivers camels rabbits SARS-CoV MERS-CoV MVA vaccine transmission RBD MERS-CoV nucleocapsid protein complement animal model pseudotyped virus combination MERS-coronavirus peptide mouse model spike protein receptor-binding domain prevention and treatment coronaviruses coronavirus spike glycoprotein therapeutic antibodies vaccine platforms mutation severe acute respiratory syndrome coronavirus pathogenesis fusion inhibitor Coronavirus murine CD8+ T cell epitope lipidomics authentic virus correlates of immunity vaccines neutralizing monoclonal antibodies Middle East respiratory syndrome coronavirus small-molecule inhibitor Middle East Respiratory Syndrome Virus DPP4 pyroptosis cross-neutralization inflammation Qatar spike proteins One Health HKU4 nanobodies mechanism of action neutralizing antibody host factors UHPLC–MS |
| ISBN | 3-03921-851-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367737603321 |
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Du Lanying
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Trends on Vanadium Chemistry, Biochemistry, and Medicinal Chemistry
| New Trends on Vanadium Chemistry, Biochemistry, and Medicinal Chemistry |
| Autore | Gambino Dinorah |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Research & information: general
Chemistry Inorganic chemistry |
| Soggetto non controllato |
polyoxometalates
decavanadate cytotoxicity insulin-like activity diabetes therapy vanadium biochemistry vanadium speciation vanadium proteins DNA fluorescence binding constants mechanism of action oxidovanadium(V) vanadium Schiff base coordination complex low acute toxicity Oxidovanadium(V) Schiff base X-ray crystallography DNA interaction 2-aminopyrimidinium experimental and theoretical characterization DFT docking RNA/DNA vitamin E EPR tocopherol 51V NMR urethane aerosol delivery lung cancer apoptosis antineoplastic oxidovanadium(IV) phenantrholine chrysin vanadium cellular uptake anticancer albumin interaction glycosylated flavonoid oxidovanadium(IV) complex antitumoral antioxidant cell signaling cancer anticancer agents |
| ISBN | 3-0365-5765-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637783803321 |
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Gambino Dinorah
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant Foods and Underutilized Fruits as Source of Functional Food Ingredients : Chemical Composition, Quality Traits, and Biological Properties
| Plant Foods and Underutilized Fruits as Source of Functional Food Ingredients : Chemical Composition, Quality Traits, and Biological Properties |
| Autore | Donno Dario |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (82 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
yacon
Smallanthus sonchifolius prebiotic fructooligosaccharides underutilized Terminalia ferdinandiana Kakadu plum nutrition fatty acids proximate minerals kernels Buchanania obovata green plum fruit polyphenols antioxidants Indigenous Australia Clitoria ternatea L. flower extract in vitro starch digestibility hydrolysis index predicted glycemic index natural antimicrobial antioxidant mechanism of action citral polygodial anethole natural plant foods healthy properties phytochemicals agrobiodiversity human nutrition analytical strategies bioactivity unconventional fruits in vitro test natural antioxidants |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Plant Foods and Underutilized Fruits as Source of Functional Food Ingredients |
| Record Nr. | UNINA-9910674057603321 |
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Donno Dario
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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