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Antitumor and Anti-HIV Agents from Natural Products
| Antitumor and Anti-HIV Agents from Natural Products |
| Autore | Nakagawa-Goto Kyoko |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (338 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
acute toxicity
allyl isothiocyanate Angelica dahurica anti-HIV antiangiogenic antioxidants antiproliferation antiproliferative activity antiretroviral agents antitumor activity apoptosis Artemisia absinthium L. aspidosperma-type benzyl isothiocyanate bladder cancer Bousigonia mekongensis BRAF inhibitor breast cancer butanolides caffeic acid cancer cancer multidrug resistance cancer stem cell Carpesium divaricatum cell cycle cell cycle arrest cervical cancer chemistry chemoprevention cisplatin coumarins curcumin analog cytotoxicity delcosine delpheline diterpenoid alkaloids DOTA drug development drug-drug interaction epithelial-to-mesenchymal transition essential oil flavonoids G2/M phase cell cycle arrest HaCaT cells HEF cell line hepatocellular carcinoma hepatoma cells Hernandia nymphaeifolia human tumor cell lines human tumor cells inflammation Ivalin kobusine lignan glycosides lipojesaconitine marine metabolites matrix metalloproteinase medicine melanoma melanoma and breast cancer cell line Mentha aquatica var. Kenting Water Mint metastasis mitochondria-mediated apoptosis monoterpenoid indole alkaloids natural agents natural phaeosphaeride A natural products NF-κB oral squamous cell carcinoma cells oxidative stress oxypeucedanin P-glycoprotein p53 phenethyl isothiocyanate phenolic acid pseudokobusine pterostilbene quercetin reactive oxygen species resveratrol SK-Hep-1 sulforaphane tamoxifen taxol total phenolic content transforming growth factor-β1 triterpenoids tubulin inhibitor tumor suppression two-stage skin carcinogenesis ursolic acid β-lapachone |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557504803321 |
Nakagawa-Goto Kyoko
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Phytochemicals in Health and Disease
| Bioactive Phytochemicals in Health and Disease |
| Autore | Iriti Marcello |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (264 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
Acorus calamus
autophagy B16F10 cells cancer cardiovascular disease chlorogenic acid chloroquine citric acid clinical trial cognitive impairment coronavirus COVID-19 curcumin diet ethnomedicinal flavonoids food supplements HCoV-OC43 hormesis infection kaempferol kurarinone LC3 liposome liposomes malic acid matrix metalloproteinase melanoma metabolic application micronuclei molecular signals MRC-5 cell n/a nanocarriers nanocurcumin nanoformulation nanomedicine naringin nervous system neurological neurological disorders neuroprotective orientin p62/SQSTM1 protein pharmacological action pharmacological potential phytochemistry phytoestrogens PNT2 quercetin quinic acid radiation effects radioprotectors remdesivir resveratrol RNA-dependent RNA polymerase rosmarinic acid rutin SARS-CoV-2 skin rejuvenation spike glycoproteins sulforaphane toxicity transforming growth factor Ulmus parvifolia vitexin wound healing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557389003321 |
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Iriti Marcello
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular Oxidative Stress
| Cellular Oxidative Stress |
| Autore | Marino Angela |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (529 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
3-glutathionyl-4-hydroxynonanal
4-hydroxy-2-nonenal A2E acute pancreatitis adaptive immune response adipose-derived stem cells age-related macular degeneration (AMD) aging analgesic anion exchange anoikis antioxidant antioxidants apoptosis artemisinin derivatives astrocytoma cells autophagy AVD band 3 Band 3 protein bradykinin calcium ionophore A23187 cancer cardiovascular diseases cashew nuts cell homeostasis cellular redox state cigarette smoke extract circRNA cisplatin nephrotoxicity clinical CNS pathology co-ultramicronization coagulation d-Galactose diabetes diet dietary chemicals diseases epilepsy erythrocytes ferroptosis fish glucose exposure glycation HeLa hemichromes hemostasis hepatic steatosis immune system immunosenescence inflammation interleukin 1β legumes lipid dyshomeostasis liver lncRNA luteolin matrix metalloproteinase matrix metalloproteinases microparticles microvascular permeability miRNA mitochondrial function molecular hydrogen mucosal immunity n/a NAC NADPH oxidase nasal fibroblasts nasal immunity natural compounds ncRNA neurodegeneration neuroinflammation NF-κB nitric oxide donor nitrosative stress obesity oxidative stress palmitoylethanolamide palmitoylethanolamide (PEA) paracrine factors paw edema peroxide PGC-1α phytochemicals Plasmodium falciparum platelets polyphenols preeclampsia programmed cell death prooxidant pyroptosis reactive oxygen species reactive oxygen species (ROS) Retinitis pigmentosa RNA-Seq ROS RPE simvastatin SO42− SO42− uptake soy soy foods soybeans status epilepticus steroids Substance-P syk kinase inhibitors T cells tert-Bytyl hydroperoxide t-BOOH therapeutic strategies tissue inhibitor of metalloproteinases traumatic brain injury tRNA fragments Trolox vaccination vesiculation vitamin C |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557338703321 |
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Marino Angela
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Matrix Metalloproteinase
| Matrix Metalloproteinase |
| Autore | Ågren Magnus S |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (262 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
a disintegrin and metalloproteinase
ADAM ADAMTS adult aggrecan aggrecanase Agkistrodon venom allodynia anticoagulants antithrombotic apoptosis arthritis blood sampling cancer cartilage caspase-3 CD147 central nervous system chemokine cytokine cytokines diseases dorsal root ganglion ectodomain shedding EMMPRIN extracellular matrix extracellular matrix breakdown fibrinogen gastric cancer glycosaminoglycans glycosylation hemagglutinin-B high-molecular-weight heparin HIV-TB-associated IRIS IL-11 IL-16 IL-6 IL-8 inflammation inhibitor interferon interleukin interstitial collagens invasion lung matrix metalloproteinase matrix metalloproteinases matrix metalloproteinases (MMPs) matrix-metalloproteinase meprin metabolomics metalloproteases metalloproteinase metastatic dissemination MMP MMP-2 MMP-9 MMPs monocytes MT4-MMP neuropathic pain pediatric peritoneal mesothelial cell phagocytosis phosphorylation protease proteinases proteomics PTMs sICAM-1 signaling spinal nerve ligation T cells TNF-α trans-signaling transwell co-cultures tuberculosis tuberculous meningitis wound healing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557717203321 |
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Ågren Magnus S
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Matrix Metalloproteinases in Health and Disease
| Matrix Metalloproteinases in Health and Disease |
| Autore | Serra Raffaele |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (196 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
acute kidney injury
adhesion apoptosis arterial aneurysms autoantibodies biomarkers Caco-2 CD147 cGMP chronic kidney disease CKD collagenases Crohn's disease dental caries dialysis disease eGFR eNOS fibrosis genetic association health high-flux dialysis hypersensitivity pneumonitis inflammation inflammatory bowel disease iNOS integrin αMβ2 ischemia/reperfusion kidney transplantation leukocytes Mac-1 MAPKs matrix metalloproteinase matrix metalloproteinase-7 matrix metalloproteinase-9 matrix metalloproteinases metalloproteinases MMP-9 MMP1 MMP2 MMPs mouth NGAL NO on-line hemodiafiltration PAD patients periodontitis peripheral vascular disease platelets proteinuria RECK renal replacement therapy SNPs statins synthetic inhibitors TIMP TIMPs |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557409503321 |
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Serra Raffaele
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Proteases-From Basic Structure to Function to Drug Design as Targeted Therapy
| Proteases-From Basic Structure to Function to Drug Design as Targeted Therapy |
| Autore | Kwok Hang Fai |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (93 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
ADAMTS3
angiogenesis apoptosis Bowman-Birk inhibitor cancer cathepsin D CCBE1 cysteine protease inhibitor diversification extracellular matrix Gentamicin immune response KLK3 lymphangiogenesis lymphedema matrix metalloproteases matrix metalloproteinase metastasis MMP MMP14 MMP2 MMP7 MMP9 nuclei pancreatic cancer parasite PDAC phylogenetic analysis plasmin PlGF prostate-specific antigen (PSA) proteases protein structure proteolytic activation ranacyclin signal peptide stefin structure-activity relationship synergistic effect thrombin trypsin inhibitor vascular biology vascular endothelial growth factors (VEGFs) VEGF-A VEGF-B VEGF-C VEGF-D wound healing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557353103321 |
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Kwok Hang Fai
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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