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Cyanobacteria and Cyanotoxins: New Advances and Future Challenges
| Cyanobacteria and Cyanotoxins: New Advances and Future Challenges |
| Autore | Cameán Ana M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (246 p.) |
| Soggetto non controllato |
method validation
sirtuin 1 (SIRT1) arctic Cylindrospermopsin Microcystin-LR 16S rRNA gene astaxanthin secondary metabolites shotgun metagenomic sequencing time-resolved fluoroimmunoassay Histopathological evaluation cyanobacterial thresholds akinetes nutrient enrichment benthic mats cylindrospermopsin drinking water treatment plant blue-green algae supplements lettuce genotoxicity exposure bacterial community PCR microcystin-LR marine natural compounds ELISA [d-Leu1]Microcystin-LR Paracentrotus lividus tadpoles apoptosis 16S rRNA gene sequencing PSP toxins marine cyanobacteria hemolytic essay energy budget bioassays anatoxin-a Lithobates catesbeianus mixture reproductive toxicity cyanobacteria taste-and-odor compounds Procambarus clarkii drinking water saxitoxin resveratrol harmful algal blooms cytotoxicity phylogenetic analyses Yangtze estuary microcystin mutagenicity detection Artemia salina water source cyanotoxins microcystins in vitro marine sponges microcystin-LR (MC-LR) UPLC-MS/MS reservoir microbial metabolisms Aphanizomenon flos-aquae monoclonal antibody oxidative stress Nostocales |
| ISBN | 3-03921-839-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cyanobacteria and Cyanotoxins |
| Record Nr. | UNINA-9910404089003321 |
Cameán Ana M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Enzyme Inhibitor from Marine Organisms
| Enzyme Inhibitor from Marine Organisms |
| Autore | Tischler Dirk |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (130 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
sponge Monanchora pulchra
pentacyclic guanidine alkaloids GH36 α-galactosidase GH109 α-N-acetylgalactosaminidase slow-binding irreversible inhibitor monanchomycalin B monanhocidin A normonanhocidin A Alzheimer′s disease BACE1 acetylcholinesterase in silico docking phlorotannins Ulva intestinalis ACE inhibitory peptide optimization purification structural identification molecular docking secondary metabolites Mycosphaerella sp asperchalasine α-glucosidase kinase inhibitors drug development marine natural products inhibitor macroalgae marine fish protease Ulva ohnoi functional annotation structure–function relation natural products bioactives enzyme inhibition inactivation marine bacteria marine fungi marine sponges |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557107603321 |
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Tischler Dirk
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Chitin 2019
| Marine Chitin 2019 |
| Autore | Sashiwa Hitoshi |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto non controllato |
chitosan hydrogel
chitosan biotechnology RAW264.7 macrophage ?-glucosidase inhibitor bromotyrosines layer-by-layer film amphiphilic polymer conjugation marine resources antioxidant activity chitooligosaccharides methylene blue nanoparticles bulk density Eudragit® S100 lytic polysaccharide monooxygenase chitosan oleate salt curcumin RAW 264.7 cells antioxidant crude oil ball milling anti-inflammatory action enzymatic modification dissolution vaginal infections Hausner ratio crushing strength Staphylococcus epidermidis mucoadhesive film Caco-2 cell culture chitosan lactate 2D correlation spectroscopy chitosan citrate direct compression chitosan oligomers chitin deacetylase Pseudomonas aeruginosa collagen blood express method sodium carbonate HIV sexual transmission streptomycin antibacterial activity pork sausage nanocomposites chitosanase Clostridium perfringens chitinase mucoadhesion chitosan oligosaccharides chitosan tartrate Staphylococcus aureus immunostimulatory activity derivatization pH responsive release soluble chitosan complex chitin polymer film compression work wound treatment biofilms roller compaction mitogen-activated protein kinases (MAPK) Paenibacillus chitooligosaccharide mechanical property protease Polybius henslowii scaffolds electrospinning chitosan-coated liposomes phosphoinositide 3-kinases (PI3K)/Akt cytotoxicity polymorph vaginal preexposure prophylaxis Aplysina archeri antifungal activity PLGA Kawakita analysis marine sponges Tenofovir controlled release nile red |
| ISBN | 3-03936-073-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404078203321 |
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Sashiwa Hitoshi
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
apoptosis
fucoidan hepatocellular carcinoma reactive oxygen species 3-alkylpyridinium polymers nicotine nicotinic acetylcholine receptor non-small cell lung carcinoma melanoma sinulariolide proteomic mitochondria caspase cascade marine fungus sediment anthranilic acid Penicillium paneum cytotoxicity dibromotyrosine mitochondrial dysfunction oxidative stress topoisomerase epigonal organ bonnethead shark Jurkat tumor cell line hippuristanol PEL AP-1 STAT3 Akt colorectal cancer marine mollusc brominated indoles shrimp chemoprevention fatty acids carotenoids cancer nanoparticle osteosarcoma lung metastasis elisidepsin lipid rafts hydroxylated lipids fatty acid 2-hydroxylase cooperative binding membrane permeabilization marine organisms polysaccharides anticancer anticarcinogenic mechanisms of action fumigaclavine C anti-proliferation mitochondrial pathway anti-cancer anti-proliferative carotenoid cell cycle arrest fucoxanthin azoxymethane bioactive natural product isatin in vivo model Marthasterias glacialis L. palmitic acid ER-stress CHOP Antibody Drug Conjugates (ADCs) marine antitumor agents clinical trials approved antitumor agents AD0157 angiogenesis marine drug pyrrolidinedione secondary metabolites cancer preventive chemopreventive trabectedin plitidepsin tumor-associated macrophages tumor microenvironment preclinical anticancer immunity antiangiogenesis fascaplysin cyclin-dependent kinase small cell lung cancer camptothecin poly(ADP-ribose)-polymerase inhibitor breast cancer seaweed therapeutic compounds autophagy marine drugs autophagy inhibitors autophagy inducers macrolide programmed cell death energy stress araguspongine C c-Met HER2 gemcitabine pazopanib phase I safety soft tissue sarcoma pachastrissamine jaspine B carbocyclic analogue sphingosine kinase inhibitor molecular modeling ET-743 DNA minor groove binder soft tissue sarcoma chemotherapy bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) anti-metastatic activity cell adhesion β1-integrin FAK BEL-7402 cell triterpene glycosides sea cucumbers antitumor activities arrest of cell cycle antibacterial marangucyclines deep-sea Streptomyces sp. SCSIO 11594 LS-1 SNU-C5/5-FU TGF-β signaling carcinoembryonic antigen kalkitoxin Moorea producens mitochondria toxin VEGF angiogenesis inhibitor hypoxia-inducible factor-1 HIF-1 Lyngbya majuscula marine metabolites SZ-685C nonfunctioning pituitary adenomas Ecklonia cava phlorotannins dieckol migration sipholenol A ABC transporter multidrug resistance P-gp/ABCB1 BCRP/ABCG2 MRP1/ABCC1 marine natural products glioblastoma xyloketal B proliferation TRPM7 marine compound ribosomal protein genes snoRNA FAU RPS30 SNORA62 evolution Porifera Penicillium brevicompactum Brevianamide Mycochromenic acid derivative antifouling Caribbean sponge plakortide endoperoxide leukemia multi-drug resistant leukemia Sarcophyton ehrenbergi soft coral terpenes cembranoids cytotoxic activity molecular docking uveal melanoma oxidative stress virtual screening Topo I inhibitor low toxic natural product Ulva fasciata selenium-containing polysaccharide-protein complex pseudopterosin NF-κB p65 inflammation cytokine release IL-6 TNFα MCP-1 glucocorticoid receptor paulomycins Micromonospora antitumor Cantabrian Sea-derived actinobacteria puupehenones sponges antiangiogenic antitumoral porifera/sponge cancer genes molecular oncology bromophenol molecular mechanisms cell cycle PI3K/Akt p38/ERK ROS human lung cancer glycosaminoglycans antiproliferative heparan sulphate gliotoxin NSCLC adriamycin resistance Sepia ink polysaccharides antitumour chemosensitization anticoagulation sea anemone drug discovery endothelial cells RGD motif kunitz type inhibitor prostate cancer antioxidant natural marine compounds marine biotechnology microalgae marine sponges Aeroplysinin Isofistularin pheochromocytoma and paraganglioma metastasis cancer progression cell adhesion molecules integrin β1 hypoxia phycocyanin non-small cell lung cancer NF-κB signaling marine-derived drugs bioanalysis chromatography manzamine A epithelial-mesenchymal transition lung cancer circulating tumor cells signal transduction cisplatin Lampetra morii buccal gland cystatin F anti-angiogenesis cystatin superfamily Antimicrobial peptide (AMP) Tilapia piscidin 4 (TP4) non-small cell lung cancer (NSCLC) itampolin A FBDD p38α novel inhibitor tetracenomycin X cyclin D1 proteasomal degradation p38 c-JUN λ-carrageenan heparanase anticoagulant depolymerisation cell migration Aspergillus naphthopyrones endophytic fungus Leathesia nana mangrove-derived actinomycete ansamycins divergolides apoptosis-inducing activity actinomycin EMT invasion low molecular weight fucoidan extract N-Ras neuroblastoma-rat sarcoma Cancer programmed cell death-ligand 1 programmed cell death-ligand 2 human sarcoma cell line (HT1080 cells) human normal diploid fibroblast (TIG-1 cells) chimera chemical conjugation anticancer agent hybridization α9-nicotinic acetylcholine receptors (nAChRs) breast cancer cells αO-conotoxin GeXIVA targeted therapy gorgonian Leptogorgia humulane sesquiterpenoids anticancer activity 12-deacetyl-12-epi-scalaradial HeLa cells Nur77 MAPK/ERK pathway Mycalin A C15 acetogenins synthetic analogues antiproliferative activity A375 and HeLa cell lines polyoxygenated steroids sponge Haliclona gracilis Thalassia testudinum thalassiolin B polyphenols CYP1A1 benzo[a]pyrene JNK1/2 natural products synergism A549 cells cytoskeleton P2X7 receptor pollution anti-angiogenic gene expression HSP90 inhibitor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Natural Products and Obesity
| Marine Natural Products and Obesity |
| Autore | Vasconcelos Vítor |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (194 p.) |
| Soggetto non controllato |
natural compounds
anti-obesity drugs high fat diet Ishige okamurae fat zebrafish Nile red fat metabolism assay physical exercise JAK2-STAT3 metabolite profiling obesity chlorophyll derivatives brown seaweed Skate skin PPAR? marine alga marine biodiscovery skate skin lipolytic leptin uncoupling protein 1 3T3-L1 cells glucolipid metabolism disorder nutrition bioactivity chitosan oligosaccharide diphlorethohydroxycarmalol (DPHC) nutraceuticals whole small animal models high-fat diet adipocyte dyslipidemia bioactivity screening peroxisome proliferator-activated receptor gamma white adipose tissue antiobesity fatty liver disease thermal proteome profiling inflammation cyanobacteria Raja kenojei Arthrospira maxima cellularity adipocytes bioactive compound collagen peptide double-blind bisabolane-related compounds proliferation fatty acid metabolism cholesterol metabolism collagen randomized controlled trial mechanisms of action murine pre-adipocytes adipogenesis fucan marine sponges label-free quantitative proteomics diabetes body fat |
| ISBN | 3-03921-192-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346840903321 |
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Vasconcelos Vítor
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural Product Genomics and Metabolomics of Marine Bacteria
| Natural Product Genomics and Metabolomics of Marine Bacteria |
| Autore | Crüsemann Max |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (244 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Moorena bouillonii
marine natural products chemogeography metabolomics natural products dereplication antibiotics marine sponges plant pathogen cyclodepsipeptides marine Actinobacteria Streptomyces spp antibiotic sea cucumber HCV Actinobacteria marine Polar genomics specialised metabolites chitin chitinase chitin degradation machinery Pseudoalteromonas secondary metabolites bacterial natural products mass spectrometry genome mining paired omics keratinases keratinolytic proteases marine-derived Streptomyces genomic comparison cyanobacteria symbionts comparative genomics biosynthetic gene clusters Indonesia biodiversity novel antibiotics drug screening bioactivity gene cluster networking GNPS enterococci genome-wide analysis bacteriocins probiotics wild marine species Neolyngbya anticancer drug discovery South China Sea wenchangamide Moorea producens CuSO4·5H2O assisted differential gDNA isolation filamentous bacteria micrococcin P1 and P2 stalked diatoms |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557611903321 |
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Crüsemann Max
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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