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Bioactive Molecules from Extreme Environments II
| Bioactive Molecules from Extreme Environments II |
| Autore | Giordano Daniela (Researcher) |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (336 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
Arctic/Antarctic
marine bioprospecting marine natural product terpene terpenoid biotechnological application drug discovery microalgae Muriellopsis spray drying freeze-drying lutein supercritical fluid extraction cyclic tripeptides antibacterial Antarctica sponge-derived fungus Aspergillus insulicola psychrophiles Antarctic bacteria Lipopolysaccharide (LPS) lipid A structural characterization MALDI-TOF mass spectrometry marine natural products Mollusca Gastropoda chemical ecology crustin antimicrobial peptides shrimp deep-sea hydrothermal vent deep-sea microorganism fungus Penicillium griseofulvum anti-food allergy fungal metabolites Paenibacillus Arctic Svalbard Marfey’s method DP4 calculation quinone reductase lipopeptide 3-amino-2-pyrrolidinone green synthesis biomaterials metal antibiotics nanotechnology deep sea natural products Mariana Trench Dermacoccus abyssi MT 1.1T 13C-NMR chemical shift linear and multiple regression (DFT)-UV-Vis spectral calculation phenoxazine dermacozine absorption maxima in the near infrared region Antarctica sponges mycalols marine biotechnology antifungal activity Bacillus amyloliquefaciens Panama disease Fusarium oxysporum f. sp. cubense bioactive compound iturin A5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557343003321 |
Giordano Daniela (Researcher)
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Natural Products from the Red Sea
| Bioactive Natural Products from the Red Sea |
| Autore | Rateb Mostafa |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (152 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
Aspergillus falconensis
OSMAC azaphilones X-ray diffraction NF-κB inhibition LC-HRESIMS Stylissa carteri ceramide cerebroside docking cytotoxic activity co-cultivation phenazine sponge-associated actinomycetes antibacterial antibiofilm DNA gyrase pyruvate kinase ergosterol derivative metabolic analysis docking studies seagrass Thalassodendron ciliatum Red Sea sponges marine actinomycetes Streptomyces coelicolor LY001 halogenated 3-phenylpropanoic acid derivatives diketopiperazine alkaloids structural determinations antimicrobial activities Red Sea marine natural products marine organisms biodiversity marine metagenomics bioactivity Sinularia polydactyla soft coral steroids cytotoxic anti-inflammatory neuroprotective androgen receptor Actinokineospora Rhodococcus co-culture metabolomics antimalarial epicotripeptin phragamide Epicoccum Alternaria antimicrobial |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557540903321 |
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Rateb Mostafa
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Enzyme Inhibitor from Marine Organisms
| Enzyme Inhibitor from Marine Organisms |
| Autore | Tischler Dirk |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (130 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
sponge Monanchora pulchra
pentacyclic guanidine alkaloids GH36 α-galactosidase GH109 α-N-acetylgalactosaminidase slow-binding irreversible inhibitor monanchomycalin B monanhocidin A normonanhocidin A Alzheimer′s disease BACE1 acetylcholinesterase in silico docking phlorotannins Ulva intestinalis ACE inhibitory peptide optimization purification structural identification molecular docking secondary metabolites Mycosphaerella sp asperchalasine α-glucosidase kinase inhibitors drug development marine natural products inhibitor macroalgae marine fish protease Ulva ohnoi functional annotation structure–function relation natural products bioactives enzyme inhibition inactivation marine bacteria marine fungi marine sponges |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557107603321 |
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Tischler Dirk
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
apoptosis
fucoidan hepatocellular carcinoma reactive oxygen species 3-alkylpyridinium polymers nicotine nicotinic acetylcholine receptor non-small cell lung carcinoma melanoma sinulariolide proteomic mitochondria caspase cascade marine fungus sediment anthranilic acid Penicillium paneum cytotoxicity dibromotyrosine mitochondrial dysfunction oxidative stress topoisomerase epigonal organ bonnethead shark Jurkat tumor cell line hippuristanol PEL AP-1 STAT3 Akt colorectal cancer marine mollusc brominated indoles shrimp chemoprevention fatty acids carotenoids cancer nanoparticle osteosarcoma lung metastasis elisidepsin lipid rafts hydroxylated lipids fatty acid 2-hydroxylase cooperative binding membrane permeabilization marine organisms polysaccharides anticancer anticarcinogenic mechanisms of action fumigaclavine C anti-proliferation mitochondrial pathway anti-cancer anti-proliferative carotenoid cell cycle arrest fucoxanthin azoxymethane bioactive natural product isatin in vivo model Marthasterias glacialis L. palmitic acid ER-stress CHOP Antibody Drug Conjugates (ADCs) marine antitumor agents clinical trials approved antitumor agents AD0157 angiogenesis marine drug pyrrolidinedione secondary metabolites cancer preventive chemopreventive trabectedin plitidepsin tumor-associated macrophages tumor microenvironment preclinical anticancer immunity antiangiogenesis fascaplysin cyclin-dependent kinase small cell lung cancer camptothecin poly(ADP-ribose)-polymerase inhibitor breast cancer seaweed therapeutic compounds autophagy marine drugs autophagy inhibitors autophagy inducers macrolide programmed cell death energy stress araguspongine C c-Met HER2 gemcitabine pazopanib phase I safety soft tissue sarcoma pachastrissamine jaspine B carbocyclic analogue sphingosine kinase inhibitor molecular modeling ET-743 DNA minor groove binder soft tissue sarcoma chemotherapy bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) anti-metastatic activity cell adhesion β1-integrin FAK BEL-7402 cell triterpene glycosides sea cucumbers antitumor activities arrest of cell cycle antibacterial marangucyclines deep-sea Streptomyces sp. SCSIO 11594 LS-1 SNU-C5/5-FU TGF-β signaling carcinoembryonic antigen kalkitoxin Moorea producens mitochondria toxin VEGF angiogenesis inhibitor hypoxia-inducible factor-1 HIF-1 Lyngbya majuscula marine metabolites SZ-685C nonfunctioning pituitary adenomas Ecklonia cava phlorotannins dieckol migration sipholenol A ABC transporter multidrug resistance P-gp/ABCB1 BCRP/ABCG2 MRP1/ABCC1 marine natural products glioblastoma xyloketal B proliferation TRPM7 marine compound ribosomal protein genes snoRNA FAU RPS30 SNORA62 evolution Porifera Penicillium brevicompactum Brevianamide Mycochromenic acid derivative antifouling Caribbean sponge plakortide endoperoxide leukemia multi-drug resistant leukemia Sarcophyton ehrenbergi soft coral terpenes cembranoids cytotoxic activity molecular docking uveal melanoma oxidative stress virtual screening Topo I inhibitor low toxic natural product Ulva fasciata selenium-containing polysaccharide-protein complex pseudopterosin NF-κB p65 inflammation cytokine release IL-6 TNFα MCP-1 glucocorticoid receptor paulomycins Micromonospora antitumor Cantabrian Sea-derived actinobacteria puupehenones sponges antiangiogenic antitumoral porifera/sponge cancer genes molecular oncology bromophenol molecular mechanisms cell cycle PI3K/Akt p38/ERK ROS human lung cancer glycosaminoglycans antiproliferative heparan sulphate gliotoxin NSCLC adriamycin resistance Sepia ink polysaccharides antitumour chemosensitization anticoagulation sea anemone drug discovery endothelial cells RGD motif kunitz type inhibitor prostate cancer antioxidant natural marine compounds marine biotechnology microalgae marine sponges Aeroplysinin Isofistularin pheochromocytoma and paraganglioma metastasis cancer progression cell adhesion molecules integrin β1 hypoxia phycocyanin non-small cell lung cancer NF-κB signaling marine-derived drugs bioanalysis chromatography manzamine A epithelial-mesenchymal transition lung cancer circulating tumor cells signal transduction cisplatin Lampetra morii buccal gland cystatin F anti-angiogenesis cystatin superfamily Antimicrobial peptide (AMP) Tilapia piscidin 4 (TP4) non-small cell lung cancer (NSCLC) itampolin A FBDD p38α novel inhibitor tetracenomycin X cyclin D1 proteasomal degradation p38 c-JUN λ-carrageenan heparanase anticoagulant depolymerisation cell migration Aspergillus naphthopyrones endophytic fungus Leathesia nana mangrove-derived actinomycete ansamycins divergolides apoptosis-inducing activity actinomycin EMT invasion low molecular weight fucoidan extract N-Ras neuroblastoma-rat sarcoma Cancer programmed cell death-ligand 1 programmed cell death-ligand 2 human sarcoma cell line (HT1080 cells) human normal diploid fibroblast (TIG-1 cells) chimera chemical conjugation anticancer agent hybridization α9-nicotinic acetylcholine receptors (nAChRs) breast cancer cells αO-conotoxin GeXIVA targeted therapy gorgonian Leptogorgia humulane sesquiterpenoids anticancer activity 12-deacetyl-12-epi-scalaradial HeLa cells Nur77 MAPK/ERK pathway Mycalin A C15 acetogenins synthetic analogues antiproliferative activity A375 and HeLa cell lines polyoxygenated steroids sponge Haliclona gracilis Thalassia testudinum thalassiolin B polyphenols CYP1A1 benzo[a]pyrene JNK1/2 natural products synergism A549 cells cytoskeleton P2X7 receptor pollution anti-angiogenic gene expression HSP90 inhibitor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural Product Genomics and Metabolomics of Marine Bacteria
| Natural Product Genomics and Metabolomics of Marine Bacteria |
| Autore | Crüsemann Max |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (244 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Moorena bouillonii
marine natural products chemogeography metabolomics natural products dereplication antibiotics marine sponges plant pathogen cyclodepsipeptides marine Actinobacteria Streptomyces spp antibiotic sea cucumber HCV Actinobacteria marine Polar genomics specialised metabolites chitin chitinase chitin degradation machinery Pseudoalteromonas secondary metabolites bacterial natural products mass spectrometry genome mining paired omics keratinases keratinolytic proteases marine-derived Streptomyces genomic comparison cyanobacteria symbionts comparative genomics biosynthetic gene clusters Indonesia biodiversity novel antibiotics drug screening bioactivity gene cluster networking GNPS enterococci genome-wide analysis bacteriocins probiotics wild marine species Neolyngbya anticancer drug discovery South China Sea wenchangamide Moorea producens CuSO4·5H2O assisted differential gDNA isolation filamentous bacteria micrococcin P1 and P2 stalked diatoms |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557611903321 |
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Crüsemann Max
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Selected Papers from XVI MaNaPro and XI ECMNP
| Selected Papers from XVI MaNaPro and XI ECMNP |
| Autore | Vasconcelos Vítor |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (214 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
marine-derived fungi
secondary metabolites polyketides drimanes meroterpenoids cytotoxicity benthic cyanobacteria tropical mangrove Guadeloupe phylogenetic diversity chemical diversity molecular networking antimicrobial activity proteasome inhibition dolabellane secosteroids soft coral marine natural products actinomycetes biofouling antifouling antibiofilm napyradiomycins hybrid isoprenoids drug discovery bioprospection Dysidea avara avarone/avarol redox-active compounds quinones and hydroquinones dioxothiazinoquinone Schistosoma mansoni Plasmodium falciparum Leishmania spp 3D-SAR analysis DFT studies PhenoTarget approach MRMS protein-ligand complex polycarpine holothurian diatom anti-fouling compounds saponins triterpene glycosides mass spectrometry Antarctica ascidian microbiome microbial diversity palmerolide A co-occurrence porphyrinoids annelida marine bioproducts HPLC-DAD toxicity photosensitizers chirality configurational analysis distance geometry NMR spectroscopy NOE data residual dipolar couplings Sarcophyton cherbonnieri cembranoid anti-inflammatory activity elastase release superoxide anion generation osteoarthritis amentadione preclinical osteoarthritis models marine compounds Cystoseira usneoides inflammation mineralization chondrocytes synoviocytes cartilage explants |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557670103321 |
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Vasconcelos Vítor
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthesis of Marine Natural Products and Molecules Inspired by Marine Substances II
| Synthesis of Marine Natural Products and Molecules Inspired by Marine Substances II |
| Autore | Manzo Emiliano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (111 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
In-silico drug design
virtual screening Avicennia alba gag polyprotein homology modeling ADMET molecular dynamics simulation divergent total synthesis marine natural products tetracyclic meroterpenoids aureol (−)-majusculoic acid anti-inflammation LPS CCK-8 animal studies marine alkaloids biological activity cancer cardiovascular diseases inflammation chemical synthesis ilamycins rufomycins cyclomarins tuberculosis malaria cyclopeptides biosynthesis total synthesis natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557724503321 |
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Manzo Emiliano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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