Adverse Reactions to Biomaterials: State of the Art in Biomaterial Risk Assessment, Immunomodulation and In Vitro Models for Biomaterial Testing |
Autore | Engin Vrana Nihal |
Pubbl/distr/stampa | Frontiers Media SA, 2019 |
Descrizione fisica | 1 electronic resource (137 p.) |
Soggetto topico |
Civil engineering, surveying & building
Biotechnology |
Soggetto non controllato |
biomaterials
in vitro models immunomodulation risk immune reaction hydrogels macrophages tissue engineering innate immunity hyaluronic acid gelatin |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Adverse Reactions to Biomaterials |
Record Nr. | UNINA-9910557236303321 |
Engin Vrana Nihal | ||
Frontiers Media SA, 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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AMP-Activated Protein Kinase Signalling |
Autore | Neumann Dietbert |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
Descrizione fisica | 1 electronic resource (452 p.) |
Soggetto non controllato |
HDACs
transcription epigenetics spermatozoa par complex A769662 MDCK skeletal muscle AID phosphorylation energy metabolism monocytes autophagy CML liver hindlimb suspension pregnancy preeclampsia gestational diabetes mellitus CaMKK2 assisted reproduction techniques nutrient-sensing signals sonic hedgehog protein acetylation glycogen storage disease AMPK adenosine monophosphate-activated protein kinase AICAR indirect calorimetry IL-1? MyHC I(?) HDAC4/5 endothelial cells infection hepatocyte p70S6K lipid metabolism host defense exercise kidney disease heat shock protein ?RIM mycobacteria activation loop developmental origins of health and disease (DOHaD) CREB TAK1 metabolic-inflammation phenylephrine AMP-activated protein kinase (AMPK) KATs 2-methoxyestradiol DNA methylation NLRP3 pump ?-linker steatosis AMPK kinase stress endothelial nitric-oxide synthase vasodilation adherent junctions epithelial cells glycogen Akt synaptic activation cellular energy sensing glucose uptake transporter co-expression atrophy nutrigenomics motility vasoconstriction fatty acid oxidation oxidative stress AS160 membrane histone modification sirtuin 1 (SIRT1) chromatin remodeling insulin signalling dietary fatty acids ULK CMML adaptive thermogenesis mTOR MDS mechanical unloading AML endothelial function medulloblastoma PKA adipose tissue NAD+ membranes nutrition ZO-1 TBC1D4 adipocyte soluble Adenylyl cyclase metabolism renin-angiotensin system energy utilization proteasome differentiation signaling peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) hypertrophy AMP-activated protein kinase metabolic disease LKB1 soleus muscle macrophages Immediate early genes CBS benign motor endplate remodeling ionomycin nectin-afadin tight junctions resveratrol protein kinase B regrowth mitochondria protein synthesis energy deficiency catechol-O-methyltransferase fiber-type microarrays carrier acetyl-CoA hypertension 3T3-L1 hypothalamus food intake |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910346858503321 |
Neumann Dietbert | ||
MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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An Evolutionary and Environmental Perspective of the Interaction of Nanomaterials with the Immune System-The Outcomes of the EU Project PANDORA |
Autore | Boraschi Diana |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (218 p.) |
Soggetto topico |
Medicine
Pharmacology |
Soggetto non controllato |
innate immunity
infection microbiome survival nanomaterials nanoparticles copper earthworms Eisenia fetida cosmetic formulation cosmetic lifecycle hydrophobic compound nano-TiO2 nano safety marine invertebrate metabolomics avian pathogenic Escherichia coli nanovaccine outer membrane vesicles immune response broiler earthworm coelomocyte TiO2 nanoparticles reactive oxygen species lipid peroxidation alkaline comet assay phagocytosis apoptosis gene expression hemocytes Mytilus in vitro scanning electron microscopy innate memory Schistosoma mansoni monocytes macrophages vaccination gold nanoparticles cerium nanoparticles woodlice haemocyte environmental models human cells markers NPs testing immune system inflammation tolerance engineered nanomaterial (ENM) nanoparticle (NP) gold nanoparticle (AuNP) plant Arabidopsis thaliana plant growth stress response transcriptomics proteomics |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910576882703321 |
Boraschi Diana | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Arteriogenesis and Therapeutic Neovascularization |
Autore | Deindl Elisabeth |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (220 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
factor VII activating protease
HABP2 VEGF matrigel neo-vascularization hind limb ischemia angiogenesis arteriogenesis ERK endothelial cells inflammation macrophages atherosclerosis pericyte rAAV capillary microRNA isomiRs epitranscriptome neovascularization A-to-I editing m6A RNA modifications RNA methylation lower extremity arterial disease peripheral arterial disease blood flow restriction activity-based benefits training effects effect mechanism hyperoxygenation vein graft disease vascular biology spinal cord ischemia paraplegia aortic disease TAAA collateral network paraspinous compartment NO NOTCH innate immunity mast cell GH and eNOS IGF-I oxidative stress and arterial inflammation vascular homeostasis GHAS trial collateral artery growth SMC proliferation potassium channel KV1.3 KCa3.1 FGFR-1 Egr-1 PDFG-R αSM-actin TLR2/6 femoral artery ligation blood flow recovery collateral growth VHL loss of function microRNA-212/132 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557495503321 |
Deindl Elisabeth | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Autophagy in Tissue Injury and Homeostasis |
Autore | Lin Pei-Hui |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (322 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
aging
dietary restriction acute kidney injury mitochondria autophagy mitophagy ischemia renal tubular cells diabetic nephropathy exosomes mTOR innate immunity immune cell inflammasome Paneth cell inflammatory bowel disease Crohn's disease hepatocytes hepatic stellate cells sinusoidal endothelial cells macrophages fibrosis cirrhosis hepatocellular carcinoma biomarkers cell death glutaminase metabolism molecular rehabilitation kidney diseases oxidative stress inflammation ATGs intestinal homeostasis inflammatory bowel diseases HCC therapy Autophagy acute lung injury idiopathic pulmonary fibrosis COPD tuberculosis PAH cystic fibrosis Beclin-1 cardiac dysfunction sepsis endotoxemia muscle regeneration stem cell immune macrophage senescence exercise caloric restriction diabetic retinopathy PINK1 Notoginsenoside R1 ethanol LC3 apoptosis Sertoli cell Parkin TFEB infertility AMPK FOXO MTOR parkin spinal cord injury traumatic brain injury autophagic flux neuronal cell death lysosomal damage |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557284203321 |
Lin Pei-Hui | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Biomarkers for Diagnosis, Complications and Therapy Effects in Civilization Diseases Management |
Autore | Komosinska-Vassev Katarzyna |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (208 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
pharmacogenomics
NGS variants personalized medicine FSHR personalized drug therapy hedgehog-interacting protein impaired fasting glucose impaired glucose tolerance newly diagnosed diabetes normal glucose tolerance inflammatory bowel disease ulcerative colitis Crohn’s disease extracellular matrix components hyaluronan inflammatory bowel diseases (IBD) Crohn’s disease (CD) ulcerative colitis (UC) sulfated glycosaminoglycans (sGAG) hyaluronan (HA) soluble part of syndecan-1 (sCD138) microRNA cardiovascular disease diabetes mortality antiplatelet therapy platelet reactivity Let-7e miR-126 miR-223 miR-125a-3p CCL11 CCL24 CCL26 CCR3 CRC adiponectin adipokines rheumatology obesity overweight case control study rheumatoid arthritis TNF-α inhibitors bone turnover markers PINP PICP NTX-I CTX-I RANKL/OPG ovarian cancer interleukin 21 interleukin 22 lymphocytes macrophages dendritic cells innate lymphoid cells breast cancer extracellular matrix proteins tumorigenesis tumor microenvironment |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910566458203321 |
Komosinska-Vassev Katarzyna | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Candida albicans A Major Fungal Pathogen of Humans |
Autore | Richardson Jonathan |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (182 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences Microbiology (non-medical) |
Soggetto non controllato |
Candida albicans
acridine antifungal topoisomerase inhibitor candidiasis 1,3,4-oxadiazole drug discovery antifungal agents drug resistance toxicity biofilm invasive Candida infections invasive fungal infections antifungal prophylaxis newborns surgery neonatal surgery multivalency anti-adhesion glycoconjugates glycomimetics Candida C. albicans XCL1 metamorphic protein fold-switching protein antifungal peptide polymorphism hyphal morphogenesis hyphal activation signal transduction pathways cell cycle regulation sphingolipids myriocin fungal infections epigenetic yeast chromatin hyphae human fungal pathogen nutrient sensing amino acid metabolism proline catabolism mitochondria SPS-sensor nitrogen catabolite repression glucose repression immunometabolism metabolism macrophages epithelial cells glycolysis glucose moonlighting proteins |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910580211203321 |
Richardson Jonathan | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Cell Biology of Galectins |
Autore | Timoshenko Alexander |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (202 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
galectin-7
p53 MMP-9 cancer gain-of-function vasculature gene expression tube formation sprouting VEGF integrins galectin extracellular matrix microenvironment Yersinia enterocolitica YopP Galectin-1 nitric oxide macrophages epithelial tissues apoptosis targeting inhibitors β-hairpin β-sandwich blood group B lectin sugar code LGALS16 placenta brain tissues cell differentiation transcription factor miRNA galectin-3 cardiac fibrosis heart failure atrial fibrillation chronic inflammation MMPs microRNAs lncRNAs pectin structure and function bioactive polysaccharides galectin-3 inhibition galacto-oligosaccharides galectins intestinal epithelial cells β-3'galactosyllactose immunomodulation mucosal immunity O-GlcNAc unconventional secretion extraembryonic endoderm |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910580216003321 |
Timoshenko Alexander | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Cellular and Molecular Mechanisms of Nephropathic Cystinosis |
Autore | Levtchenko Elena N |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (230 p.) |
Soggetto topico |
Medicine
Pharmacology |
Soggetto non controllato |
cystinosis
cysteamine bone osteoclast genotype CD34+ hematopoietic stem and progenitor cells gene therapy pre-clinical studies investigational new drug application clinical trial disulfiram mice zebrafish fertility azoospermia hypogonadism histopathology mouse model lysosomal storage disease cell and animal models infantile nephropathic cystinosis bone-muscle wasting fibroblast growth factor 23 osteoclasts sclerostin leptin fractures nephropathic cystinosis hollow fiber membrane 3-dimensional models autophagy macrophages inflammasome proximal tubular cells endocytosis apoptosis chitotriosidase interleukins galectin-3 novel therapies endolysosome epithelial cell differentiation homeostasis lysosomal storage diseases mitochondrial distress kidney proximal tubule programmed cell death central nervous system cortical atrophy arterial spin labelling cystine blood level lysosomal storage disorder history treatment strategies for cystinosis newborn screening clinical course CTNS-pathogenic variants newborn screening for cystinosis kidney progenitors cell model biomarkers cystine kidney therapeutic monitoring |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910585941103321 |
Levtchenko Elena N | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Diet and Immune Function |
Autore | Childs Caroline E |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (314 p.) |
Soggetto non controllato |
immunonutrition
supplementation superoxide dismutase (SOD) fermented milk selenocysteine dendritic cells lipoxygenase (LOX) chronic inflammatory conditions formulation immune system cytokines skeletal muscle zinc non-digestible carbohydrates Toll-like receptor carbohydrates fiber lymphocytes antibody infants liver macrophage inflammatory process probiotic plant older people gut barrier infection amino acids gut T helper 1 (Th1) immunity T cells bioactive peptide inhibitor of kappa kinase (IKK) inflammation adhesion molecules leukocytes human milk oligosaccharides vitamin D food structure vitamin E mitogen-activated protein Kinase (MAPK) gut microbiota weaning homeostasis intestinal immune system extra-cellular signal regulated kinases (ERK) cyclooxygenase (COX) oxidative stress life course polyphenols oligosaccharides micronutrients Th17 obesity tolerance arachidonic acid growth factors anti-inflammation age-related immunity prebiotic biomarker microbiome functional foods immunosenescence nutrition molecular mechanisms metabolism macronutrients toll-like receptor 4 sepsis nutrition guidelines microbiota immunomodulation inflammatory markers elderly Th1/Th17 response adults reactive oxygen species (ROS) anorexia nervosa macrophages autoimmune diseases fatty acids T cell Treg breast milk nitric oxide synthase (NOS) chemokines anti-tumorigenic metabolites deficiency protein hydrolysate nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) cancer |
ISBN | 3-03921-613-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910404080503321 |
Childs Caroline E | ||
MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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