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Emerging Role of Lipids in Metabolism and Disease
| Emerging Role of Lipids in Metabolism and Disease |
| Autore | Pallottini Valentina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (308 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
neutral sphingomyelinase
radiation sphingomyelin metabolism pathology cell signaling brain adipose tissue breast cancer epinephrine breast reconstruction epicardial fat thickness visceral fat thickness high-sensitivity c-reactive protein leptin gender female hippocampus frontal cortex adiponectin haptoglobin lipocalin BDNF synaptic proteins phosphatidylinositol 4,5-bisphosphate phospholipase C cholesterol high-cholesterol diet BET proteins cell proliferation epigenetics HMGCR JQ1 LDLr lipid metabolism SREBP TMEM97 atherosclerosis diabetes mellitus cardiovascular disease chronic inflammation hyperglycemia mutations lipid fatty acid glyceride steroid phospholipid oral drug absorption prodrug phospholipase A2 (PLA2) acid sphingomyelinase SOD liver eicosanoids ischemic stroke ischemia lipoproteins polyunsaturated fatty acids angiogenesis high-density lipoprotein endothelial cell metabolism metabolic reprogramming pulmonary fibrosis lipid mediators sphingolipids sphingosine-1-phosphate sphingosine kinase 1 prostaglandins lysophosphatidic acid autotaxin G-protein coupled receptors lysocardiolipin acyltransferase phospholipase D oxidized phospholipids DNA damage response double strand breaks ATM ionizing radiation metabolic stress oxidative stress p53 nuclear sphingolipids lipophagy lipolysis lipid droplets lipid storage diseases lipid metabolism diseases mTORC1 TFEB Cholesterol Fatty acids Lipid mediators Lipids Lipophagy Sphingolipids |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557800303321 |
Pallottini Valentina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Killing Cancer : Discovery and Selection of New Target Molecules
| Killing Cancer : Discovery and Selection of New Target Molecules |
| Autore | Kallunki Tuula |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (302 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
ferlin
myoferlin dysferlin otoferlin C2 domain plasma membrane sulconazole NF-κB IL-8 mammosphere breast cancer stem cells AF1Q MLLT11 WNT STAT esophageal cancer prognosis mTORC1 mTORC2 metabolism rapalogs mTOR inhibitors cancer metabolism mTOR in immunotherapy nutrient metabolism kinase inhibitors mTOR signaling MAPK kinase ERK1 ERK2 CD domain Rolled SCH772984 VRT-11E sevenmaker cancer therapy EMT lysosome lysosome-mediated invasion MZF1 phosphorylation PAK4 SUMOylation transcription factor zinc finger glucocorticoids 3D growth nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-κB) epithelial-mesenchymal transition anoikis proliferation targeted cancer therapy disulfiram NPL4 replication stress DNA damage BRCA1 BRCA2 ATR pathway PDAC TCIRG1 ATP6V0a3 invasion migration matrix degradation pH-regulation autophagy multidrug resistance in cancer drug efflux pumps ATP-binding cassette transporter breast cancer resistance protein (BCRP) ABCG2 pyrazolo-pyrimidine derivative SCO-201 colorectal cancer immunotherapy inflammation microsatellite instability oncofetal chondroitin sulfate chondroitin sulfate cancer solid tumors target pediatric cancer VAR2 dexamethasone thyroid cancer microgravity space environment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Killing Cancer |
| Record Nr. | UNINA-9910557648103321 |
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Kallunki Tuula
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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mTOR in Human Diseases
| mTOR in Human Diseases |
| Autore | Dormond Olivier |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto non controllato |
primary cilia
neurodegeneration nutrient sensor PI3K transcriptomics phosphorylation metabolic reprogramming autophagy Alzheimer's disease rapalogs liver angiogenesis mTOR complex MBSCs advanced biliary tract cancers Medulloblastoma epithelial to mesenchymal transition AMPK p70S6K lipid metabolism thyroid cancer sodium iodide symporter (NIS)/SLC5A5 male fertility anesthesia illumina mTOR inhibitor miRNA Hutchinson-Gilford progeria syndrome (HGPS) eIFs Emery-Dreifuss muscular dystrophy (EDMD) glucose AKT oral cavity squamous cell carcinoma (OSCC) glucose and lipid metabolism cellular signaling aging tumor microenvironment rapamycin leukemia chloral hydrate rapalogues schizophrenia T-cell acute lymphoblastic leukemia senescence lamin A/C neurotoxicity neurodevelopment inhibitor methamphetamine pulmonary fibrosis mTOR mTOR inhibitors combination therapy proteolysis fluid shear stress tumour cachexia biomarkers synapse gluconeogenesis mTOR signal pathway Sertoli cells immunosenescence miRNome protein aggregation senolytics metabolism NGS mTORC2 mTORC1 metabolic diseases IonTorrent apoptosis dopamine receptor nocodazole microenvironment everolimus acute myeloid leukemia immunotherapy spermatogenesis bone remodeling signalling targeted therapy ageing therapy NVP-BEZ235 fructose physical activity laminopathies MC3T3-E1 cells cell signaling microRNA cancer lipolysis melatonin Parkinson's disease |
| ISBN | 3-03921-061-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684303321 |
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Dormond Olivier
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Muscle Homeostasis and Regeneration : From Molecular Mechanisms to Therapeutic Opportunities
| Muscle Homeostasis and Regeneration : From Molecular Mechanisms to Therapeutic Opportunities |
| Autore | Musarò Antonio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (500 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
lysine
mTORC1 satellite cells proliferation skeletal muscle growth muscle satellite cell transthyretin thyroid hormone myogenesis exosomes skeletal muscle genotype genetic variation muscle phenotypes sarcopenia aging calcium homeostasis hibernation mitochondria sarcoplasmic reticulum Acvr1b Tgfbr1 myostatin Col1a1 fibrosis atrophy IGF2R muscle homeostasis inflammation muscular dystrophy pericytes macrophages Nfix phagocytosis RhoA-ROCK1 splicing isoforms CRISPR-Cas9 exon deletion NF-Y muscle differentiation C2C12 cells denervation neuromuscular junction heavy resistance exercise acetylcholine receptor cell culture neonatal myosin neural cell adhesion molecule biomarkers mitophagy mitochondrial dynamics mitochondrial quality control mitochondrial-derived vesicles (MDVs) mitochondrial-lysosomal axis Hibernation electron microscopy immunocytochemistry α-smooth muscle actin confocal microscopy connexin 43 connexin 26 gap junctions myofibroblasts Platelet-Rich Plasma transforming growth factor (TGF)-β1 muscle regeneration inflammatory response cell precursors experimental methods stem cell markers muscles heterotopic ossification skeletal muscle stem and progenitor cells HO precursors muscle atrophy septicemia mitochondrial fusion mitochondrial fission iPSC extracellular vesicles Drosophila muscle genetic control muscle diversification fascicle myofiber myofibril sarcomere hypertrophy hyperplasia splitting radial growth longitudinal growth exercise muscle stem cells stem cells niche neuromuscular disorders Duchenne muscular dystrophy pharmacological approach single-cell mass cytometry skeletal muscle regeneration skeletal muscle homeostasis fibro/adipogenic progenitors myogenic progenitors muscle populations evolution metazoans differentiation transdifferentiation muscle precursors regenerative medicine stem cells FAPs tissue niche growth factors muscle pathology |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Muscle Homeostasis and Regeneration |
| Record Nr. | UNINA-9910557587003321 |
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Musarò Antonio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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