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Killing Cancer : Discovery and Selection of New Target Molecules
| Killing Cancer : Discovery and Selection of New Target Molecules |
| Autore | Kallunki Tuula |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (302 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
ferlin
myoferlin dysferlin otoferlin C2 domain plasma membrane sulconazole NF-κB IL-8 mammosphere breast cancer stem cells AF1Q MLLT11 WNT STAT esophageal cancer prognosis mTORC1 mTORC2 metabolism rapalogs mTOR inhibitors cancer metabolism mTOR in immunotherapy nutrient metabolism kinase inhibitors mTOR signaling MAPK kinase ERK1 ERK2 CD domain Rolled SCH772984 VRT-11E sevenmaker cancer therapy EMT lysosome lysosome-mediated invasion MZF1 phosphorylation PAK4 SUMOylation transcription factor zinc finger glucocorticoids 3D growth nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-κB) epithelial-mesenchymal transition anoikis proliferation targeted cancer therapy disulfiram NPL4 replication stress DNA damage BRCA1 BRCA2 ATR pathway PDAC TCIRG1 ATP6V0a3 invasion migration matrix degradation pH-regulation autophagy multidrug resistance in cancer drug efflux pumps ATP-binding cassette transporter breast cancer resistance protein (BCRP) ABCG2 pyrazolo-pyrimidine derivative SCO-201 colorectal cancer immunotherapy inflammation microsatellite instability oncofetal chondroitin sulfate chondroitin sulfate cancer solid tumors target pediatric cancer VAR2 dexamethasone thyroid cancer microgravity space environment |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Killing Cancer |
| Record Nr. | UNINA-9910557648103321 |
Kallunki Tuula
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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mTOR in Human Diseases
| mTOR in Human Diseases |
| Autore | Dormond Olivier |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto non controllato |
primary cilia
neurodegeneration nutrient sensor PI3K transcriptomics phosphorylation metabolic reprogramming autophagy Alzheimer's disease rapalogs liver angiogenesis mTOR complex MBSCs advanced biliary tract cancers Medulloblastoma epithelial to mesenchymal transition AMPK p70S6K lipid metabolism thyroid cancer sodium iodide symporter (NIS)/SLC5A5 male fertility anesthesia illumina mTOR inhibitor miRNA Hutchinson-Gilford progeria syndrome (HGPS) eIFs Emery-Dreifuss muscular dystrophy (EDMD) glucose AKT oral cavity squamous cell carcinoma (OSCC) glucose and lipid metabolism cellular signaling aging tumor microenvironment rapamycin leukemia chloral hydrate rapalogues schizophrenia T-cell acute lymphoblastic leukemia senescence lamin A/C neurotoxicity neurodevelopment inhibitor methamphetamine pulmonary fibrosis mTOR mTOR inhibitors combination therapy proteolysis fluid shear stress tumour cachexia biomarkers synapse gluconeogenesis mTOR signal pathway Sertoli cells immunosenescence miRNome protein aggregation senolytics metabolism NGS mTORC2 mTORC1 metabolic diseases IonTorrent apoptosis dopamine receptor nocodazole microenvironment everolimus acute myeloid leukemia immunotherapy spermatogenesis bone remodeling signalling targeted therapy ageing therapy NVP-BEZ235 fructose physical activity laminopathies MC3T3-E1 cells cell signaling microRNA cancer lipolysis melatonin Parkinson's disease |
| ISBN | 3-03921-061-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684303321 |
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Dormond Olivier
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases
| Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases |
| Autore | Rustum Youcef M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (166 p.) |
| Soggetto non controllato |
isoselenourea
malignant chemotherapeutics epigenetics antitumor activity methylseleninic acid mTOR inhibitors tumor heterogeneity hypoxia ER stress melanoma EMT lipid peroxidation immune evasion hypoxia-inducible factors (HIFs) selenium-binding protein 1 glutathione DNA damage hSP56 apoptosis tocopherol anticancer viability SELENBP1 selenium clear-cell renal cell carcinoma microRNAs SBP1 entosis PD-L1 miRNA cancer stem cells cell plasticity disease clear cell renal cell carcinoma HIF head and neck cancer selenium species VEGF STAT3 hypoxia-inducible factor methylselenocysteine anticancer agent Se-containing nanoparticles DNA damage and repair radiation seleno-l-methionine cancer tumor microenvironment methylselenoesters |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346851003321 |
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Rustum Youcef M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Renal Cell Carcinoma
| Renal Cell Carcinoma |
| Autore | López José I |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (500 p.) |
| Soggetto topico |
Renal cell carcinoma
Kidneys - Cancer |
| Soggetto non controllato |
N-glycomapping
SMAD proteins patient survival pro-IL-1? survival prediction inflammation markers tumor migration prognostic factors practical approach circular RNAs in a clinico-genomic predictive model glycomarkers review nephrectomy uric acid VEGF inhibitors metabolic reprogramming collecting duct carcinoma curcumin metabolome profiling identification of circular RNAs IL-2 experimental validation of circular RNA Raf/MEK/ERK HOT PI3K/Akt/mTOR pentose phosphate pathway kidney cancer LOT mutation RCC polybromo-1 pale cell MMP-9 gene expression recurrence free survival chromosomal loss IL-1? chronic kidney disease glutathione transferase omega 2 label-free glutathione transferase omega 1 emerging entity copy number alteration FOXO3 predictive role tumor slice culture tyrosine kinase inhibitors PPP ESC CDKN1A expression metastasis PD-L1 diagnostic and prognostic markers EVI1 copy number loss RNA sequencing NK cells glutathione metabolism clear cell renal cell carcinoma renal cell cancer proliferation eosinophilic variant Xp11 translocation renal cell carcinoma prognosis invasion immune infiltration IL4R? FISH 11) translocation renal cell carcinoma tumor microenvironment metabolome hyperosmolality toxicity ALK drug sensitivity t(6 copy number analysis urine genetic association polymorphism solute carrier proteins kidney metastatic ccRCC molecular genetic features recurrence-free survival chromophobe renal cell carcinoma unclassified renal tumor overall survival mTOR inhibitors mTOR JAK2 von Hippel-Lindau miR-155-5p glycoproteomics PBRM1 miR-133b survival TFE3 TFEB oncocytic renal tumor immune checkpoint inhibitors biomarker MMP10 TCGA ghrelin EMT like checkpoint inhibitors MiT family translocation renal cell carcinoma gene signature sarcomatoid transforming growth factor beta clear cell Renal Cell Carcinoma tumor adhesion renal cancer unclassified renal cell carcinoma Papillary renal cell carcinoma (pRCC) miR-146a-5p renal cell everolimus integrins cytoreductive nephrectomy immunotherapy predictive factors immunohistochemistry MTA2 IL13R?1 targeted therapy intratumour heterogeneity aurora A TCA cycle AMP-activated protein kinases cancer-specific survival programmed death-ligand 1 efficacy renal cell carcinoma anaplastic lymphoma kinase rearrangement TFEB-amplified renal cell carcinoma statins cancer immunotherapy microRNA new entity proteome profiling |
| ISBN | 3-03928-639-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087003321 |
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López José I
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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