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Killing Cancer : Discovery and Selection of New Target Molecules
| Killing Cancer : Discovery and Selection of New Target Molecules |
| Autore | Kallunki Tuula |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (302 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
3D growth
ABCG2 AF1Q anoikis ATP-binding cassette transporter ATP6V0a3 ATR pathway autophagy BRCA1 BRCA2 breast cancer resistance protein (BCRP) breast cancer stem cells C2 domain cancer cancer metabolism cancer therapy CD domain chondroitin sulfate colorectal cancer dexamethasone disulfiram DNA damage drug efflux pumps dysferlin EMT epithelial-mesenchymal transition ERK1 ERK2 esophageal cancer ferlin glucocorticoids IL-8 immunotherapy inflammation invasion kinase inhibitors lysosome lysosome-mediated invasion mammosphere MAPK kinase matrix degradation metabolism microgravity microsatellite instability migration MLLT11 mTOR in immunotherapy mTOR inhibitors mTOR signaling mTORC1 mTORC2 multidrug resistance in cancer myoferlin MZF1 n/a NF-κB NPL4 nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-κB) nutrient metabolism oncofetal chondroitin sulfate otoferlin PAK4 PDAC pediatric cancer pH-regulation phosphorylation plasma membrane prognosis proliferation pyrazolo-pyrimidine derivative rapalogs replication stress Rolled SCH772984 SCO-201 sevenmaker solid tumors space environment STAT sulconazole SUMOylation target targeted cancer therapy TCIRG1 thyroid cancer transcription factor VAR2 VRT-11E WNT zinc finger |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Killing Cancer |
| Record Nr. | UNINA-9910557648103321 |
Kallunki Tuula
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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mTOR in Human Diseases / Olivier Dormond
| mTOR in Human Diseases / Olivier Dormond |
| Autore | Dormond Olivier |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
primary cilia
neurodegeneration nutrient sensor PI3K transcriptomics phosphorylation metabolic reprogramming autophagy Alzheimer's disease rapalogs liver angiogenesis mTOR complex MBSCs advanced biliary tract cancers Medulloblastoma epithelial to mesenchymal transition AMPK p70S6K lipid metabolism thyroid cancer sodium iodide symporter (NIS)/SLC5A5 male fertility anesthesia illumina mTOR inhibitor miRNA Hutchinson-Gilford progeria syndrome (HGPS) eIFs Emery-Dreifuss muscular dystrophy (EDMD) glucose AKT oral cavity squamous cell carcinoma (OSCC) glucose and lipid metabolism cellular signaling aging tumor microenvironment rapamycin leukemia chloral hydrate rapalogues schizophrenia T-cell acute lymphoblastic leukemia senescence lamin A/C neurotoxicity neurodevelopment inhibitor methamphetamine pulmonary fibrosis mTOR mTOR inhibitors combination therapy proteolysis fluid shear stress tumour cachexia biomarkers synapse gluconeogenesis mTOR signal pathway Sertoli cells immunosenescence miRNome protein aggregation senolytics metabolism NGS mTORC2 mTORC1 metabolic diseases IonTorrent apoptosis dopamine receptor nocodazole microenvironment everolimus acute myeloid leukemia immunotherapy spermatogenesis bone remodeling signalling targeted therapy ageing therapy NVP-BEZ235 fructose physical activity laminopathies MC3T3-E1 cells cell signaling microRNA cancer lipolysis melatonin Parkinson's disease |
| ISBN |
9783039210619
3039210610 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684303321 |
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Dormond Olivier
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases
| Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases |
| Autore | Rustum Youcef M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (166 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
anticancer
anticancer agent antitumor activity apoptosis cancer cancer stem cells cell plasticity chemotherapeutics clear cell renal cell carcinoma clear-cell renal cell carcinoma microRNAs disease DNA damage DNA damage and repair EMT entosis epigenetics ER stress glutathione head and neck cancer HIF hSP56 hypoxia hypoxia-inducible factor hypoxia-inducible factors (HIFs) immune evasion isoselenourea lipid peroxidation malignant melanoma methylseleninic acid methylselenocysteine methylselenoesters miRNA mTOR inhibitors PD-L1 radiation SBP1 Se-containing nanoparticles SELENBP1 selenium selenium species selenium-binding protein 1 seleno-l-methionine STAT3 tocopherol tumor heterogeneity tumor microenvironment VEGF viability |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346851003321 |
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Rustum Youcef M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Renal Cell Carcinoma
| Renal Cell Carcinoma |
| Autore | López José I |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (500 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
11) translocation renal cell carcinoma
ALK AMP-activated protein kinases anaplastic lymphoma kinase rearrangement aurora A biomarker cancer immunotherapy cancer-specific survival CDKN1A expression checkpoint inhibitors chromophobe renal cell carcinoma chromosomal loss chronic kidney disease circular RNAs in a clinico-genomic predictive model clear cell renal cell carcinoma clear cell Renal Cell Carcinoma collecting duct carcinoma copy number alteration copy number analysis copy number loss curcumin cytoreductive nephrectomy diagnostic and prognostic markers drug sensitivity efficacy emerging entity EMT like eosinophilic variant ESC everolimus EVI1 experimental validation of circular RNA FISH FOXO3 gene expression gene signature genetic association ghrelin glutathione metabolism glutathione transferase omega 1 glutathione transferase omega 2 glycomarkers glycoproteomics HOT hyperosmolality identification of circular RNAs IL-1? IL-2 IL13R?1 IL4R? immune checkpoint inhibitors immune infiltration immunohistochemistry immunotherapy inflammation markers integrins intratumour heterogeneity invasion JAK2 kidney kidney cancer label-free LOT metabolic reprogramming metabolome metabolome profiling metastasis metastatic ccRCC microRNA miR-133b miR-146a-5p miR-155-5p MiT family translocation renal cell carcinoma MMP-9 MMP10 molecular genetic features MTA2 mTOR mTOR inhibitors mutation N-glycomapping n/a nephrectomy new entity NK cells oncocytic renal tumor overall survival pale cell Papillary renal cell carcinoma (pRCC) patient survival PBRM1 PD-L1 pentose phosphate pathway PI3K/Akt/mTOR polybromo-1 polymorphism PPP practical approach predictive factors predictive role pro-IL-1? prognosis prognostic factors programmed death-ligand 1 proliferation proteome profiling Raf/MEK/ERK RCC recurrence free survival recurrence-free survival renal cancer renal cell renal cell cancer renal cell carcinoma review RNA sequencing sarcomatoid SMAD proteins solute carrier proteins statins survival survival prediction t(6 targeted therapy TCA cycle TCGA TFE3 TFEB TFEB-amplified renal cell carcinoma toxicity transforming growth factor beta tumor adhesion tumor microenvironment tumor migration tumor slice culture tyrosine kinase inhibitors unclassified renal cell carcinoma unclassified renal tumor uric acid urine VEGF inhibitors von Hippel-Lindau Xp11 translocation renal cell carcinoma |
| ISBN | 3-03928-639-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087003321 |
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López José I
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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