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AMP-Activated Protein Kinase Signalling
| AMP-Activated Protein Kinase Signalling |
| Autore | Neumann Dietbert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (452 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
?-linker
?RIM 2-methoxyestradiol 3T3-L1 A769662 acetyl-CoA activation loop adaptive thermogenesis adenosine monophosphate-activated protein kinase adherent junctions adipocyte adipose tissue AICAR AID Akt AML AMP-activated protein kinase AMP-activated protein kinase (AMPK) AMPK AMPK kinase AS160 assisted reproduction techniques atrophy autophagy beiging CaMKK2 carrier catechol-O-methyltransferase CBS cellular energy sensing chromatin remodeling CML CMML co-expression CREB developmental origins of health and disease (DOHaD) dietary fatty acids differentiation DNA methylation endothelial cells endothelial function endothelial nitric-oxide synthase energy deficiency energy metabolism energy utilization epigenetics epithelial cells exercise fatty acid oxidation fiber-type food intake gestational diabetes mellitus glucose uptake glycogen glycogen storage disease HDAC4/5 HDACs heat shock protein hepatocyte hindlimb suspension histone modification host defense hypertension hypertrophy hypothalamus IL-1? Immediate early genes indirect calorimetry infection insulin signalling ionomycin KATs kidney disease lipid metabolism liver LKB1 macrophages MDCK MDS mechanical unloading medulloblastoma membrane membranes metabolic disease metabolic-inflammation metabolism microarrays mitochondria monocytes motility motor endplate remodeling mTOR mycobacteria MyHC I(?) n/a NAD+ nectin-afadin NLRP3 nutrient-sensing signals nutrigenomics nutrition oxidative stress p70S6K par complex peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) phenylephrine phosphorylation PKA preeclampsia pregnancy proteasome protein acetylation protein kinase B protein synthesis pump regrowth renin-angiotensin system resveratrol signaling sirtuin 1 (SIRT1) skeletal muscle soleus muscle soluble Adenylyl cyclase sonic hedgehog spermatozoa steatosis stress synaptic activation TAK1 TBC1D4 tight junctions transcription transporter ULK vasoconstriction vasodilation ZO-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346858503321 |
Neumann Dietbert
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Inhibitors
| Anticancer Inhibitors |
| Autore | Fantacuzzi Marialuigia |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (216 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
breast cancer
tamoxifen LY294002 synergism apoptosis cell cycle tea (Camellia sinensis) flowers BTFS A2780/CP70 ovarian cancer cells S phase cell cycle arrest nicotinamide phosphoribosyltransferase NAD+ biosynthesis inhibitor azacyclohexane anticancer drug drug design enthalpy effect NSCLC Cathepsin K cell proliferation cell migration cell invasion mTOR isatin-hydrazones cytotoxicity CDK2 inhibitor ATP competitive inhibitor ADME analysis receptor tyrosine kinases protein-protein interactions protein engineering directed evolution angiogenesis binding affinity agonistic activity saponins phytochemicals tea (Camellia sinensis) flower ovarian cancer autophagy ZMYND8 tumorigenesis epigenetic regulation pro-oncogenic effects tumor suppression tacrine-coumarin derivatives DNA topoisomerases I, II lung carcinoma cells A549 chemotherapy prodrug drug targeting overexpressed enzymes ADC ADEPT GDEPT LEAPT PROTAC cyclin-dependent kinase cancer resistance small molecule inhibitors PROTACs statins pancreatic cancer DNA microarray pitavastatin cerivastatin simvastatin fluvastatin atorvastatin pravastatin HMG-CoA reductase inhibitors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069203321 |
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Fantacuzzi Marialuigia
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products : Volume 2
| Antitumoral Properties of Natural Products : Volume 2 |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (300 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
13-ethylberberine
Akt AKT anthraquinones anti-cancer anti-cancer activity anti-cancer agents anti-tumor activity anticancer Antioxidant activities antioxidants antioxidation antiproliferation agents Antiproliferative antiproliferative activity antitumoral activity antrodin C apoptosis AR Artemisia absinthium ASE Aspergillus fumigatus ATM-Chk2 autophagic flux inhibition autophagy bee venom betulinic acid Brazilian Cerrado biome cancer cancer stem cells capsazepine carrageenan Catalpa speciosa Celastraceae cell cycle arrest cell proliferation cell signaling cephalotaxine cervical cancer Cheiloclinium cognatum chemotherapeutic adjuvant chemotherapy chiral resolution CIP2A CLE-10 CLEFMA Colocasia esculenta colorectal cancer cells copper Cordyceps sinensis coronarin D CrataBL cryptolepine Cucurbitacin B cytotoxic activity cytotoxicity Dendrobium officinale diallyl disulfide dicentrine DLD-1 cells doxorubicin drug resistance ECD calculation EGFR endoplasmic reticulum stress entrapment efficiency Euphorbia tirucalli FAK/S6K1 flavonoids folk medicine food bioactive FOXO1 fruit Ganoderma tsugae gastric cancer gastric cancer cells gefitinib-resistant NSCLC Gene expression glioblastoma glioblastoma multiforme glioma glucose uptake glycosyltransferase grape leaves human neuroblastoma cells IL-6/JAK2/STAT3 inflammation inflammatory diseases ingenol invasion isochromanes isocryptolepine JNK lactoferrin hydrolysate LC3 lichen Licochalcone A lipogenesis lung adenocarcinoma lysosomal degradation lysosomal membrane permeabilization Magnolia acuminata manganese MAPK MCF-7 cells MDA-MB-231 melanoma melittin mesenchymal stem cells metabolic stability metastasis microenvironment migration mitochondrial membrane potential mitochondrial ROS mitochondrial-dependent pathway molecular mechanism mTOR multiple myeloma n/a naringenin natural compounds natural product alkaloids natural products natural yellow Monascus pigments NCI-60 cancer cell line necrotic neferine neocryptolepine NF-κB no-toxicity Nutraceuticals oncogene osteosarcoma p38 patuletin phenols phloretin phytochemicals PI3K/AKT/mTOR PI3K/Akt/mTOR pathway plant lectin plant-derived foods plantation mode Plenckia populnea porphyran preclinical tests pristimerin pro-apoptotic effects proanthocyanins prostate cancer protease inhibitor protein kinase C protein synthesis inhibition Pulsatilla saponin D quality control quercetagetin quercetin ROS RT-R breast cancer cells Salacia crassifolia Salacia elliptica SB365 seaweed secondary metabolites semi-synthetic derivative SREBP-1 stable nanocapsules stemness potential structure activity relationships structure elucidation tarin Taxus cuspidata temozolomide TNF-α TP traditional preparation transcriptional regulation triterpenoids TRPV1 tumidulin ursolic acid vegetable water-soluble zerumbone Zeylenone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antitumoral Properties of Natural Products |
| Record Nr. | UNINA-9910557531303321 |
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Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products
| Antitumoral Properties of Natural Products |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (344 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
13-ethylberberine
Akt AKT anthraquinones anti-cancer anti-cancer activity anti-cancer agents anti-tumor activity anticancer Antioxidant activities antioxidants antioxidation antiproliferation agents Antiproliferative antiproliferative activity antitumoral activity antrodin C apoptosis AR Artemisia absinthium ASE Aspergillus fumigatus ATM-Chk2 autophagic flux inhibition autophagy bee venom betulinic acid Brazilian Cerrado biome cancer cancer stem cells capsazepine carrageenan Catalpa speciosa Celastraceae cell cycle arrest cell proliferation cell signaling cephalotaxine cervical cancer Cheiloclinium cognatum chemotherapeutic adjuvant chemotherapy chiral resolution CIP2A CLE-10 CLEFMA Colocasia esculenta colorectal cancer cells copper Cordyceps sinensis coronarin D CrataBL cryptolepine Cucurbitacin B cytotoxic activity cytotoxicity Dendrobium officinale diallyl disulfide dicentrine DLD-1 cells doxorubicin drug resistance ECD calculation EGFR endoplasmic reticulum stress entrapment efficiency Euphorbia tirucalli FAK/S6K1 flavonoids folk medicine food bioactive FOXO1 fruit Ganoderma tsugae gastric cancer gastric cancer cells gefitinib-resistant NSCLC Gene expression glioblastoma glioblastoma multiforme glioma glucose uptake glycosyltransferase grape leaves human neuroblastoma cells IL-6/JAK2/STAT3 inflammation inflammatory diseases ingenol invasion isochromanes isocryptolepine JNK lactoferrin hydrolysate LC3 lichen Licochalcone A lipogenesis lung adenocarcinoma lysosomal degradation lysosomal membrane permeabilization Magnolia acuminata manganese MAPK MCF-7 cells MDA-MB-231 melanoma melittin mesenchymal stem cells metabolic stability metastasis microenvironment migration mitochondrial membrane potential mitochondrial ROS mitochondrial-dependent pathway molecular mechanism mTOR multiple myeloma n/a naringenin natural compounds natural product alkaloids natural products natural yellow Monascus pigments NCI-60 cancer cell line necrotic neferine neocryptolepine NF-κB no-toxicity Nutraceuticals oncogene osteosarcoma p38 patuletin phenols phloretin phytochemicals PI3K/AKT/mTOR PI3K/Akt/mTOR pathway plant lectin plant-derived foods plantation mode Plenckia populnea porphyran preclinical tests pristimerin pro-apoptotic effects proanthocyanins prostate cancer protease inhibitor protein kinase C protein synthesis inhibition Pulsatilla saponin D quality control quercetagetin quercetin ROS RT-R breast cancer cells Salacia crassifolia Salacia elliptica SB365 seaweed secondary metabolites semi-synthetic derivative SREBP-1 stable nanocapsules stemness potential structure activity relationships structure elucidation tarin Taxus cuspidata temozolomide TNF-α TP traditional preparation transcriptional regulation triterpenoids TRPV1 tumidulin ursolic acid vegetable water-soluble zerumbone Zeylenone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557419703321 |
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Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Autophagy in Tissue Injury and Homeostasis
| Autophagy in Tissue Injury and Homeostasis |
| Autore | Lin Pei-Hui |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (322 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
acute kidney injury
acute lung injury aging AMPK apoptosis ATGs autophagic flux autophagy Autophagy Beclin-1 biomarkers caloric restriction cardiac dysfunction cell death cirrhosis COPD Crohn's disease cystic fibrosis diabetic nephropathy diabetic retinopathy dietary restriction endotoxemia ethanol exercise exosomes fibrosis FOXO glutaminase HCC therapy hepatic stellate cells hepatocellular carcinoma hepatocytes idiopathic pulmonary fibrosis immune immune cell infertility inflammasome inflammation inflammatory bowel disease inflammatory bowel diseases innate immunity intestinal homeostasis ischemia kidney diseases LC3 lysosomal damage macrophage macrophages metabolism mitochondria mitophagy molecular rehabilitation mTOR MTOR muscle regeneration n/a neuronal cell death Notoginsenoside R1 oxidative stress PAH Paneth cell parkin Parkin PINK1 renal tubular cells senescence sepsis Sertoli cell sinusoidal endothelial cells spinal cord injury stem cell TFEB traumatic brain injury tuberculosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557284203321 |
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Lin Pei-Hui
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Metabolomics 2018 / Paula Guedes De Pinho, Márcia Carvalho, Joana Pinto
| Cancer Metabolomics 2018 / Paula Guedes De Pinho, Márcia Carvalho, Joana Pinto |
| Autore | De Pinho Paula Guedes |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (184 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
cell transporters
pharmacodynamics cell growth in vitro study metabolomic signatures endometabolome lung cancer metabolomics chemometric methods bladder cancer mTOR metabolite profiling metabolic pathways hepatocellular carcinoma glutamate senescence MCF7 breath analysis bio actives biomarker gas chromatography–mass spectrometry (GC–MS) GC-MS lung omics nutraceuticals glutaminase metabolism acylcarnitines Erwinaze Kidrolase glutathione targeted metabolomics apoptosis SLC1A5 essential amino acids cancer progression ASCT2 HR MAS alanine analytical platforms volatile organic compound glutaminolysis isotope tracing analysis asparaginase vitamin E breast cancer prognosis early diagnosis tocotrienols NMR prostate cancer in vitro cancer MDA-MB-231 |
| ISBN |
9783039213467
3039213466 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367563603321 |
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De Pinho Paula Guedes
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Essential Pathways and Circuits of Autism Pathogenesis
| Essential Pathways and Circuits of Autism Pathogenesis |
| Autore | Gul Dolen |
| Pubbl/distr/stampa | Frontiers Media SA, 2016 |
| Descrizione fisica | 1 online resource (181 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Neurosciences |
| Soggetto non controllato |
Cell signaling
Cerebellum Hypothalamus mTOR Neurodevelopmental disorders Oxytocin Striatum |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910220043003321 |
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Gul Dolen
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| Frontiers Media SA, 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Looking Beyond Pattern Recognition: Perturbations in Cellular Homeostasis and Metabolism as Emerging Regulators of Dendritic Cell Function
| Looking Beyond Pattern Recognition: Perturbations in Cellular Homeostasis and Metabolism as Emerging Regulators of Dendritic Cell Function |
| Autore | Osorio Fabiola |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 online resource (128 p.) |
| Soggetto topico |
Immunology
Medicine and Nursing |
| Soggetto non controllato |
Autophagy
Cellular metabolism Dendritic Cells epigenetics er stress Fc gamma receptor mTOR Myosin Na+ balance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Looking Beyond Pattern Recognition |
| Record Nr. | UNINA-9910557899103321 |
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Osorio Fabiola
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Pathways in Cancers
| Molecular Pathways in Cancers |
| Autore | Cristóbal Ion |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (284 p.) |
| Soggetto topico |
Medicine and Nursing
Oncology |
| Soggetto non controllato |
acetylation
actin cytoskeletal reorganization adaptive immunity advanced ovarian cancer anti-receptor therapy BET inhibitors biomarkers bladder cancer initiation breast cancer CALR cancer cancer immunology cancer therapeutics carcinogenicity CD99 agonist complement system DUSP1 EGFR dimerization endocytosis epigenetic epigenome epithelial cells FAK dephosphorylation genome glioblastoma gp120 hepatocellular carcinoma human immunodeficiency virus type 1 immune checkpoint inhibitors immune evasion immunotherapy innate immunity JAK2 luminal breast cancer MAPK matrix protein p17 metastasis metastatic melanoma methylation migration and invasion mitochondria molecular targeted agents MPL MS-determined phosphopeptides mTOR myeloproliferative neoplasms n/a Nef NIMA-related kinase 1 (NEK1) non-coding RNA OMD oncogenic signaling pathway ovarian cancer oxidative stress OXPHOS pancreatic ductal adenocarcinoma partial EMT patient survival pBRD4 PI3K PP2A PRELP prognosis prostate cancer PTPN12 Rac1 reactive oxygen species resistance reverse transcriptase RhoA SET signaling pathways small-cell lung cancer Snail splicing pathway TAK-228 Tat thioridazine (THD) tight junction tousled-like kinase (TLK) TPOR trastuzumab tripeptide triple negative breast cancer triple-negative breast cancer tumor immune microenvironment tumor microenvironment tumor suppression gene Warburg effect yes-associated protein 1 (YAP1) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566473703321 |
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Cristóbal Ion
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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mTOR in Human Diseases / Olivier Dormond
| mTOR in Human Diseases / Olivier Dormond |
| Autore | Dormond Olivier |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
primary cilia
neurodegeneration nutrient sensor PI3K transcriptomics phosphorylation metabolic reprogramming autophagy Alzheimer's disease rapalogs liver angiogenesis mTOR complex MBSCs advanced biliary tract cancers Medulloblastoma epithelial to mesenchymal transition AMPK p70S6K lipid metabolism thyroid cancer sodium iodide symporter (NIS)/SLC5A5 male fertility anesthesia illumina mTOR inhibitor miRNA Hutchinson-Gilford progeria syndrome (HGPS) eIFs Emery-Dreifuss muscular dystrophy (EDMD) glucose AKT oral cavity squamous cell carcinoma (OSCC) glucose and lipid metabolism cellular signaling aging tumor microenvironment rapamycin leukemia chloral hydrate rapalogues schizophrenia T-cell acute lymphoblastic leukemia senescence lamin A/C neurotoxicity neurodevelopment inhibitor methamphetamine pulmonary fibrosis mTOR mTOR inhibitors combination therapy proteolysis fluid shear stress tumour cachexia biomarkers synapse gluconeogenesis mTOR signal pathway Sertoli cells immunosenescence miRNome protein aggregation senolytics metabolism NGS mTORC2 mTORC1 metabolic diseases IonTorrent apoptosis dopamine receptor nocodazole microenvironment everolimus acute myeloid leukemia immunotherapy spermatogenesis bone remodeling signalling targeted therapy ageing therapy NVP-BEZ235 fructose physical activity laminopathies MC3T3-E1 cells cell signaling microRNA cancer lipolysis melatonin Parkinson's disease |
| ISBN |
9783039210619
3039210610 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684303321 |
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Dormond Olivier
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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