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Advances in the Treatment of Renal Cell Carcinoma
| Advances in the Treatment of Renal Cell Carcinoma |
| Autore | Reynolds Paul |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (221 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
artesunate (ART)
autophagy biomarker biomarkers ccRCC chloroquine clear cell renal cell carcinoma cysteine cathepsin inhibitors cysteine cathepsins evolution evolutionary trajectory ferroptosis genomic signature growth inhibition hydroxychloroquine immune checkpoint inhibitors immune-based combination therapies immunotherapy individualization kidney cancer lysosome metastatic metastatic renal cell carcinoma mRCC network meta-analysis PD-L1 predictive RCC reactive oxygen species (ROS) renal cancer renal cell cancer renal cell carcinoma renal cell carcinoma (RCC) ROC-325 second line therapy soluble factors sunitib resistance TKIs Traditional Chinese Medicine (TCM) transcriptomic analysis treatment tyrosine kinase inhibitors |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557615503321 |
Reynolds Paul
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bacillus thuringiensis Toxins: Functional Characterization and Mechanism of Action
| Bacillus thuringiensis Toxins: Functional Characterization and Mechanism of Action |
| Autore | Bel Yolanda |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (340 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
3D-Cry toxins
3D-structure ABCC2 adhesion Aedes aegypti AFM anticancer activity Anticarsia gemmatalis antimicrobial peptide apoptosis Asian corn borer ATP-binding cassette subfamily a member 2 (ABCA2) Bacillus thuringiensis Bacillus thuringiensis proteins bioassay biological control Bombyx mori Bti cadherin chitin-binding protein coleopteran pests CRISPR/Cas9 Cry Cry1Ab Cry1Ac resistance Cry1Fa Cry2Ab toxin Cyt Cyt2Aa2 toxin erythrocyte membrane functional receptor genome editing gut microbiota HEK293T cell in vitro evolution insect resistance insecticidal activity insecticidal proteins Leptinotarsa decemlineata Lobesia botrana lysosome Mamestra brassicae membrane receptors minor proteins mitochondria mode of action mode of action of Cry toxin mosquito control n/a oligomer formation Ostrinia furnacalis Ostrinia nubilalis parasporins peritrophic matrix Plutella xylostella protein-lipid binding protoxin activation pyramids QCM-D rational design resistance S-layer proteins Sf21 cell line Sf9 cells Sip site-directed mutagenesis Spodoptera frugiperda Spodoptera litura Spodoptera spp., Helicoverpa armigera structure synergy tobacco budworm toxin enhancement transcription activator-like effector-nucleases (TALENs) trypsin-like midgut protease vegetative insecticidal proteins Vip Vip3A Vip3Aa |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Bacillus thuringiensis Toxins |
| Record Nr. | UNINA-9910557646103321 |
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Bel Yolanda
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Extracellular Vesicles: Biology and Potentials in Cancer Therapeutics
| Extracellular Vesicles: Biology and Potentials in Cancer Therapeutics |
| Autore | Cho William |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (394 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
adipose tissue origin mesenchymal stem cells
biomarker biomarker reservoirs biomarkers cancer cancer biomarker cancer diagnostics cancer therapeutic CD44 cell-to-cell communication diagnostic diagnostic biomarker differential ultracentrifugation disease monitoring drug carrier drug delivery drug delivery vehicle ectosomes ES-2 exosome exosomes extracellular vesicle extracellular vesicles flow cytometry glioblastoma head and neck squamous cell carcinoma (HNSCC) HIV-1 Nef human milk imaging flow cytometry immunophenotyping immunoprecipitation ionising radiation isolation large EVs liquid biopsy lymph node lysosome macrophage polarization mannose receptor melanoma cell-derived exosomes (MTEX) microbiota microRNA microRNAs microvesicle microvesicles n/a nanocarriers nanocommunicator neoplasia non-targeted effects nutrient OAW-42 ovarian cancer cells personalized cancer immunotherapy precision oncology prostate cancer proteomics purification signalling size exclusion chromatography size-exclusion chromatography small extracellular vesicles small extracellular vesicles (sEV) solid tissue spleen sucrose density cushion swarm detection therapeutic agents therapy tumor microenvironment tumor-associated macrophages tumor-derived exosomes (TEX) ultracentrifugation ultrasound |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Extracellular Vesicles |
| Record Nr. | UNINA-9910557555303321 |
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Cho William
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Killing Cancer : Discovery and Selection of New Target Molecules
| Killing Cancer : Discovery and Selection of New Target Molecules |
| Autore | Kallunki Tuula |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (302 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
3D growth
ABCG2 AF1Q anoikis ATP-binding cassette transporter ATP6V0a3 ATR pathway autophagy BRCA1 BRCA2 breast cancer resistance protein (BCRP) breast cancer stem cells C2 domain cancer cancer metabolism cancer therapy CD domain chondroitin sulfate colorectal cancer dexamethasone disulfiram DNA damage drug efflux pumps dysferlin EMT epithelial-mesenchymal transition ERK1 ERK2 esophageal cancer ferlin glucocorticoids IL-8 immunotherapy inflammation invasion kinase inhibitors lysosome lysosome-mediated invasion mammosphere MAPK kinase matrix degradation metabolism microgravity microsatellite instability migration MLLT11 mTOR in immunotherapy mTOR inhibitors mTOR signaling mTORC1 mTORC2 multidrug resistance in cancer myoferlin MZF1 n/a NF-κB NPL4 nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-κB) nutrient metabolism oncofetal chondroitin sulfate otoferlin PAK4 PDAC pediatric cancer pH-regulation phosphorylation plasma membrane prognosis proliferation pyrazolo-pyrimidine derivative rapalogs replication stress Rolled SCH772984 SCO-201 sevenmaker solid tumors space environment STAT sulconazole SUMOylation target targeted cancer therapy TCIRG1 thyroid cancer transcription factor VAR2 VRT-11E WNT zinc finger |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Killing Cancer |
| Record Nr. | UNINA-9910557648103321 |
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Kallunki Tuula
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Lysosomal Storage Disorders: Molecular Basis and Therapeutic Approaches
| Lysosomal Storage Disorders: Molecular Basis and Therapeutic Approaches |
| Autore | Moro Enrico |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (301 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
A4GALT
alpha-galactosidase A animal models astrogliosis autophagy axon guidance biomarkers bone involvement cathepsin D chloroquine clathrin Dkk1 dried blood spot endocytic pathways endocytosis enzyme replacement therapy exosomes experimental therapies Fabry disease GAA biomarker Gaucher disease Gaucher Disease gene therapy GLA gene globotriaosyl-sphingosine (lysoGb3) globotriaosylceramide (Gb3) globotriaosylsphingosine glycogen hematopoietic stem cell transplantations Hurler syndrome IGF2R/M6P iPSC Krabbe disease lyso-Gb3 lysosomal diseases lysosomal storage disorder lysosomal storage disorders lysosomal targeting lysosomal α-glucosidase lysosome lysosomes MIP-1β mucolipidosis II mucopolysaccharidosis IIIB mucopolysaccharidosis type I muscle NAGLU neurodegenerative disease neuronal circuit neuronopathy newborn screening Osteoimmunology Osteopontin Parkinson disease pharmacological chaperone therapy pharmacological chaperones Pompe disease precision medicine psychosine quantitative proteomics RANK/RANKL rhGAA satellite cells second tier test sortilin substrate reduction therapy tandem mass spectrometry TGF-beta Twitcher mouse variant interpretation viral vectors visual cortex visual system Wnt/β-catenin Wnt3a α-galactosidase A |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Lysosomal Storage Disorders |
| Record Nr. | UNINA-9910557545503321 |
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Moro Enrico
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondrial Dysfunction in Aging and Diseases of Aging / Richard H. Haas
| Mitochondrial Dysfunction in Aging and Diseases of Aging / Richard H. Haas |
| Autore | Haas Richard H |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (270 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
age-related diseases
sphingolipids glaucoma ALS neurodegeneration mitochondrial dysfunction adaptive immunity senescence de-emergence innate immunity cell danger response mitochondrial transfer axonal transport cytokines mitochondrial age-related macular degeneration prevention heart failure purinergic signaling autophagy Alzheimer's disease diabetic retinopathy proteostasis 1 immunosenescence Miro1 ROS metabolism optic nerve polypharmacy eIF2? Parkin coenzyme Q10 neurodegenerative disease DNA damage skin exercise nucleotide metabolism pasteur effect stress response inflammation retina drug-induced mitochondrial toxicity neuroinflammation exosomes reactive oxygen species 25(OH)D cardiomyopathy crabtree effect insulin resistance cardiovascular disease ageing genetic mutations metabokines mitochondria multiple sclerosis aerobic healing cycle SOD1 mitophagy PINK1 type 2 diabetes integrated cell stress response morbidity and mortality ultraviolet photoageing cancer aging 25(OH)2D lysosome NAD+ Parkinson's disease |
| ISBN |
9783039213283
3039213288 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756303321 |
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Haas Richard H
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Alveolar Epithelium : Mechanisms of Injury and Repair
| The Alveolar Epithelium : Mechanisms of Injury and Repair |
| Autore | Kasper Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (222 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
3D reconstruction
acinar micromechanics acute lung injury acute mountain sickness air-blood barrier air-liquid interface alveolar epithelial cells alveolar epithelium alveolar fluid alveolar lining layer alveolar micromechanics alveolar septal composition alveoli alveolus atelectrauma autophagy bleomycin-induced lung injury bovine carbon dioxide chlamydia dietary sugar endoplasmic reticulum epithelial cell dysfunction epithelium extracellular matrix remodeling focused ion beam scanning electron microscopy glycocalyx GSK-3β high-altitude pulmonary edema hypercapnia hyperglycemia inflammatory signaling JAM-A lung lung injury lung mechanics lung regeneration lysosomal membrane permeability lysosome microRNA-21 mitochondria model mouse lung Na,K-ATPase necrotizing oxygen diffusion limitation P2X7 receptor physical activity pneumocyte pneumonia protein oxidation pulmonary fibrosis regeneration sodium transport stem cell exhaustion structural remodeling surfactant surfactant protein B type 1 alveolar epithelial cell type 2 alveolar epithelial cell |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Alveolar Epithelium |
| Record Nr. | UNINA-9910557307703321 |
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Kasper Michael
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ubiquitin and Autophagy
| Ubiquitin and Autophagy |
| Autore | Nazarko Taras Y |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (294 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
aggrephagy
APP ATG12~5/16 complex Atg8 autophagy autophagy initiation autophagy-lysosome pathway BECN1 C. elegans cargo receptors crosstalk Cx43 degradation Dictyostelium endosome ER-phagy FIP200 GABARAP gap junction globoid cell leukodystrophy islet LC3 leukodystrophies lipophagy LIR motif lysophagy lysosome MAPLC3 mitophagy n/a neurodegenerative diseases NFAT5 nucleophagy p62 phagocytosis pinocytosis plants proteasome PSMD14 psychosine retrograde retromer SAR selective autophagy sorting nexins the ubiquitin-proteasome system tissue specificity toll-like receptor 4 TRAF6 trafficking ubiquitin ubiquitin-like protein ubiquitin-proteasome system ubiquitination UBL unfolded protein response UPR UPS xenophagy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339503321 |
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Nazarko Taras Y
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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