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Advance in the Treatment of Pediatric Leukemia
| Advance in the Treatment of Pediatric Leukemia |
| Autore | Handgretinger Rupert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (300 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
5-azacitidine
ABCC4 acute lymphoblastic leukemia acute myeloid leukemia acute pancreatitis ADC advances ALL allogeneic stem cell transplantation alternative donors AML antibody antibody-drug conjugate B-ALL BCL11B BCP-ALL bispecific T-cell engager (BiTE) CD19 CFTR childhood acute lymphoblastic leukemia children chronic myeloid leukemia CML conditioning regimen COVID-19 diagnosis DUX4 evolution of CAR T cells Fc-engineering FDA-approved CAR products future directions of CAR T cell therapy genome hematopoietic stem cell transplantation IKZF1 immunizations immunotherapy juvenile myelomonocytic leukemia L-asparaginase leukemia limitations and complications of CAR T cell therapy low-risk ALL lymphoblastic leukemia minimal residual disease myelodysplastic/myeloproliferative disorders n/a NOTCH1 NUTM1 other extramedullary relapse PAX5 pediatric pediatric leukemia Ph-like polymorphism prognosis RAS signaling risk-stratified treatment SNV T-ALL targeted therapy TcR versus CAR TRAIL transcriptome treatment treatment related toxicity tyrosine kinase inhibitor xenograft ZNF384 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576878903321 |
Handgretinger Rupert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Nanomaterials in Biomedicine
| Advances in Nanomaterials in Biomedicine |
| Autore | Ryabchikova Elena I |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (472 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
active targeting
amphiphile amphiphilic oligonucleotides angiogenesis antibacterial assay antioxidants aorta AuBSA-NPs AuNPs AuPEI-NPs biocompatible nanomaterials biodegradable biological nano-antioxidants bone marrow-derived mesenchymal stromal cells cancer carbon dots carbosilane cartilage repair catalytic dye reduction Ceiba pentandra chemoradiotherapy chemotherapy clinical translation computed tomography cytotoxicity dendron diagnosis diagnostics doxorubicin drug delivery drug delivery system electron microscopy Entada spiralis fluorescence Förster resonance energy transfer gold nanoparticles gold nanostars hard tissue engineering heart human articular cartilage hydrogels IL-1β immune response immune-checkpoint inhibitors immunogenic cell death immunotherapy inflammation iron content iron nanoparticles leukaemia leukemia lipid conjugates liver fibrosis magnetic properties magnetite nanoparticles magnetolipogels magnetoliposomes methotrexate molecular imaging molecular ultrasound nano-biomaterials nano-conjugates nano-vaccines nanobubbles nanocarriers nanomaterials nanomedicine nanoparticles nanotechnology nucleic acid delivery oncotherapy osteoarthritis oxidative stress penetration of NPs into monolayer and spheroids pH-sensitive pharmaceutical phosphoryl guanidines photoacoustic imaging photothermal therapy polyethylenimines polymeric micelles polymeric nanoparticles polymers polypropylenimine dendrimers PPI-Y pro-inflammatory cytokines rAAV vectors radiation radiosensitizer RNA-Seq scaffolds self-assembly silver nanoparticles siRNA transfection SOX9 SQUID superoxide targeted drug delivery targeted microbubbles TGF-β theranostic agents theranostics therapy thrombosis tissue engineering TNF-α triazine tyrosine-modified polyethlyenimines tyrosine-modified polypropylene-imines ultrastructure of HEK293 cells and spheroids ultrastructure of HepG2 cells and spheroids vesicles |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557724003321 |
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Ryabchikova Elena I
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bio-Functional Natural Products in Edible Resources for Human Health and Beauty
| Bio-Functional Natural Products in Edible Resources for Human Health and Beauty |
| Autore | Morikawa Toshio |
| Descrizione fisica | 1 online resource (226 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
1,8-Cineole
2-methoxy phenol 2,5-dimethylpyrazine aging of the human body anemia anthocyanin compositions anti-glycation anti-inflammation anti-inflammatory anti-inflammatory activity anti-neurodegenerative properties antianxiety anticancer activity antioxidant antiparasitic activity arylpropanoid sucroses banana inflorescences biosynthesis structural genes carotenoids ceramide chemotherapeutic drug chlorophyll ciliated cell co-treatment cognition cultivated berries curcumin dual specificity phosphatase 1 elder elevated plus-maze test fallopian tube FLT-3 freeze-drying functional food herbs gut microbiota hemoglobin HPLC-ELSD iron Lavandula stoechas essential oil leaf powder ingredients leukemia leukemic stem cell lingonberry lycoperoside medicinal plants medicine food homology melanoma cell lines n/a Notch Oryza sativa phenolic compounds phytoestrogen rice sea buckthorn secretory cell sesame oil aroma steroidal saponin sugars sweet potato tomato seed topical anti-inflammatory effect transcription factor transepidermal water loss triterpenic compounds type 2 diabetes mellitus UPLC-ESI-MS Vaccinium vitis-idaea water-immersion stress wild berries |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069303321 |
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Morikawa Toshio
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| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological Activities of Alkaloids: From Toxicology to Pharmacology
| Biological Activities of Alkaloids: From Toxicology to Pharmacology |
| Autore | Adamski Zbigniew |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (270 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
?-carboline
acetylcholinesterase acid-sensing ion channel subtype 1a acute toxicity alkaloid alkaloids antibacterial anticancer antifungal antimicrobial activity antioxidant antiviral apoptosis Apoptosis Arecoline beetles berberine Berberis thunbergii biodistribution bisbenzylisoquinoline alkaloid chanoclavine Chelidonium majus Corydalis lutea Curine cytotoxic activity cytotoxicity dehydrocrenatidine di-ester diterpenoid alkaloids Dicentra spectabilis EGFR endophyte Epichloë ergot alkaloids FAK Fumaria officinalis glycoalkaloids HPLC-DAD inflammation insect insect heart isoquinoline alkaloids leukemia lindoldhamine lipopolysaccharide livestock lung cancer cells mAchR3 Macleaya cordata macrophage Mahonia aquifolia malonyl-solamargine malonylated form Meconopsis cambrica mono-ester diterpenoid alkaloids n/a natural products natural sources neuropathic pain neutrophil nociception Ovarian cancer Palmatine plant secondary metabolites Radix Aconiti Lateralis preparations reproduction Rutidea parviflora sanguinarine secondary metabolites short-term and long-term usage solamargine Solanum melongena L. solasonine SRC Staphylococcus aureus subchronic feeding study Tenebrio molitor toxicology voltage-gated sodium channels |
| ISBN | 3-03928-928-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Biological Activities of Alkaloids |
| Record Nr. | UNINA-9910404082303321 |
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Adamski Zbigniew
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cells and Materials for Disease Modeling and Regenerative Medicine
| Cells and Materials for Disease Modeling and Regenerative Medicine |
| Autore | Abarrategi Ander |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (270 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
3D cell culture
3D models adipose tissue allografts amelogenesis biomaterials biomimicry bladder blood cancer bone and cartilage regeneration bone marrow bone tissue engineering cardiac tissue regeneration cell differentiation cementogenesis cholera toxin co-culture collagen compliance cyclic adenosine monophosphate cytokines decellularization dental pulp stem cells dentinogenesis dentogenesis devitalization disease modeling drug release materials elastin electroactive explants extracellular matrix fibrosis growth factors high hydrostatic pressure in vitro models in vivo models iPSC isoproterenol joint-on-a-chip Leigh syndrome leukemia mesenchymal stromal cells microarchitecture microenvironment mitochondrial disorder mtDNA myeloma neuron niche NSC odontogenic cells osteogenesis patterning piezoelectric psoriasis regenerative medicine rheumatoid arthritis scaffolds stem cells tissue engineering tumor-on-a-chip whole-tooth regeneration |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557403303321 |
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Abarrategi Ander
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Functionally Relevant Macromolecular Interactions of Disordered Proteins
| Functionally Relevant Macromolecular Interactions of Disordered Proteins |
| Autore | Simon Istvan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (520 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
aggregation
CABS model co-evolution coarse-grained conformational plasticity copper binding correlated mutations decision tree based artificial neural network dehydron differentially regulated genes disorder-to-order regions disordered protein disordered protein platform DNA conformational landscape DNA-protein interactions drug discovery drugs dual threshold eIF4E epiproteome evolution evolutionary couplings extracellular FG-Nups fluorescence anisotropy folding functional analysis gene ontology analysis histone lysine methyltransferase homodimer HOTAIR hydration hydrogen bond immune inter-subunit interaction interaction surface intrinsic disorder intrinsic disorder prediction intrinsically disorder proteins intrinsically disordered intrinsically disordered protein intrinsically disordered proteins intrinsically disordered proteins (IDPs) intrinsically disordered region ion pair leukemia lncRNA MC simulations MEG3 membrane-less organelle meta strategy Microarray MLL proteins MLL4 molecular machines molecular recognition feature molten globule mutual synergistic folding N-terminal prion protein neurodegenerative disease neurodegenerative diseases Nuclear pore complex oligomer p300 HAT acetylation p53 phosphorylation physiological homeostasis plant virus post-translational modification post-translational modifications potyvirus prion disease mutations protein protein aggregation protein conformation protein hydrodynamics protein intrinsic disorder protein stability protein structure protein thermostability protein-protein interaction protein-RNA interactions residue co-variation residue contact network ribosomal protein RIN4 RNA binding RNA sequencing salt bridges secretion sequential DNA bending significance voting smFRET solvent-accessible surface area Sox2 sequential DNA loading spectroscopy stabilization center statistical force fields stress response structural disorder structural domain Tau fibrillation temperature response transcription factor dosage transcription factors transcriptome unstructured proteins VPg wide-line 1H NMR |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557509403321 |
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Simon Istvan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Leukemia
| Leukemia |
| Autore | Li Weijie |
| Pubbl/distr/stampa | Brisbane, Australia, : Exon Publications, 2022 |
| Descrizione fisica | 1 online resource |
| Soggetto topico | MJCL |
| Soggetto non controllato |
acute lymphoblastic leukemia
acute myeloid leukemia with myelodysplasia related changes hairy cell leukemia hematolymphoid tumors infant leukemia leukemia leukemia pharmacogenomics measurable residual disease in acute leukemia myeloid/lymphoid neoplasms PDGFRA rearrangement secondary acute myeloid leukemia |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910617309103321 |
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Li Weijie
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| Brisbane, Australia, : Exon Publications, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (480 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
12-deacetyl-12-epi-scalaradial
3-alkylpyridinium polymers A375 and HeLa cell lines A549 cells ABC transporter actinomycin AD0157 adriamycin resistance Aeroplysinin Akt angiogenesis angiogenesis inhibitor ansamycins anthranilic acid anti-angiogenesis anti-angiogenic anti-cancer anti-metastatic activity anti-proliferation anti-proliferative antiangiogenesis antiangiogenic antibacterial Antibody Drug Conjugates (ADCs) anticancer anticancer activity anticancer agent anticancer immunity anticarcinogenic anticoagulant anticoagulation antifouling Antimicrobial peptide (AMP) antioxidant antiproliferative antiproliferative activity antitumor antitumor activities antitumoral antitumour AP-1 apoptosis apoptosis-inducing activity approved antitumor agents araguspongine C arrest of cell cycle Aspergillus autophagy autophagy inducers autophagy inhibitors azoxymethane BCRP/ABCG2 BEL-7402 cell benzo[a]pyrene bioactive natural product bioanalysis bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) bonnethead shark breast cancer breast cancer cells Brevianamide brominated indoles bromophenol buccal gland c-JUN c-Met C15 acetogenins camptothecin cancer Cancer cancer genes cancer preventive cancer progression Cantabrian Sea-derived actinobacteria carbocyclic analogue carcinoembryonic antigen Caribbean sponge carotenoid carotenoids caspase cascade cell adhesion cell adhesion molecules cell cycle cell cycle arrest cell migration cembranoids chemical conjugation chemoprevention chemopreventive chemosensitization chemotherapy chimera CHOP chromatography circulating tumor cells cisplatin clinical trials colorectal cancer cooperative binding cyclin D1 cyclin-dependent kinase CYP1A1 cystatin F cystatin superfamily cytokine release cytoskeleton cytotoxic activity cytotoxicity deep-sea depolymerisation dibromotyrosine dieckol divergolides DNA minor groove binder drug discovery Ecklonia cava elisidepsin EMT endoperoxide endophytic fungus endothelial cells energy stress epigonal organ epithelial-mesenchymal transition ER-stress ET-743 evolution FAK fascaplysin fatty acid 2-hydroxylase fatty acids FAU FBDD fucoidan fucoxanthin fumigaclavine C gemcitabine gene expression glioblastoma gliotoxin glucocorticoid receptor glycosaminoglycans gorgonian Haliclona gracilis HeLa cells heparan sulphate heparanase hepatocellular carcinoma HER2 HIF-1 hippuristanol HSP90 human lung cancer human normal diploid fibroblast (TIG-1 cells) human sarcoma cell line (HT1080 cells) humulane sesquiterpenoids hybridization hydroxylated lipids hypoxia hypoxia-inducible factor-1 IL-6 in vivo model inflammation inhibitor integrin β1 invasion isatin Isofistularin itampolin A jaspine B JNK1/2 Jurkat kalkitoxin kunitz type inhibitor Lampetra morii Leathesia nana Leptogorgia leukemia lipid rafts low molecular weight fucoidan extract low toxic LS-1 lung cancer lung metastasis Lyngbya majuscula macrolide mangrove-derived actinomycete manzamine A MAPK/ERK pathway marangucyclines marine antitumor agents marine biotechnology marine compound marine drug marine drugs marine fungus marine metabolites marine mollusc marine natural products marine organisms marine sponges marine-derived drugs Marthasterias glacialis L. MCP-1 mechanisms of action melanoma membrane permeabilization metastasis microalgae Micromonospora migration mitochondria mitochondria toxin mitochondrial pathway mitochondrial dysfunction molecular docking molecular mechanisms molecular modeling molecular oncology Moorea producens MRP1/ABCC1 multi-drug resistant leukemia multidrug resistance Mycalin A Mycochromenic acid derivative N-Ras n/a nanoparticle naphthopyrones natural marine compounds natural product natural products neuroblastoma-rat sarcoma NF-κB NF-κB signaling nicotine nicotinic acetylcholine receptor non-small cell lung cancer non-small cell lung cancer (NSCLC) non-small cell lung carcinoma nonfunctioning pituitary adenomas novel inhibitor NSCLC Nur77 osteosarcoma oxidative stress oxidative stress P-gp/ABCB1 P2X7 receptor p38 p38/ERK p38α p65 pachastrissamine palmitic acid paulomycins pazopanib PEL Penicillium brevicompactum Penicillium paneum phase I pheochromocytoma and paraganglioma phlorotannins phycocyanin PI3K/Akt plakortide plitidepsin pollution poly(ADP-ribose)-polymerase inhibitor polyoxygenated steroids polyphenols polysaccharides Porifera porifera/sponge preclinical programmed cell death programmed cell death-ligand 1 programmed cell death-ligand 2 proliferation prostate cancer proteasomal degradation proteomic pseudopterosin puupehenones pyrrolidinedione reactive oxygen species RGD motif ribosomal protein genes ROS RPS30 safety Sarcophyton ehrenbergi sea anemone sea cucumbers seaweed secondary metabolites sediment selenium-containing polysaccharide-protein complex Sepia ink polysaccharides shrimp signal transduction sinulariolide sipholenol A small cell lung cancer SNORA62 snoRNA SNU-C5/5-FU soft coral soft tissue sarcoma soft tissue sarcoma sphingosine kinase inhibitor sponge sponges STAT3 Streptomyces sp. SCSIO 11594 synergism synthetic analogues SZ-685C targeted therapy terpenes tetracenomycin X TGF-β signaling Thalassia testudinum thalassiolin B therapeutic compounds Tilapia piscidin 4 (TP4) TNFα Topo I inhibitor topoisomerase trabectedin triterpene glycosides TRPM7 tumor cell line tumor microenvironment tumor-associated macrophages Ulva fasciata uveal melanoma VEGF virtual screening xyloketal B α9-nicotinic acetylcholine receptors (nAChRs) αO-conotoxin GeXIVA β1-integrin λ-carrageenan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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MicroRNA as Biomarkers in Cancer Diagnostics and Therapy / Lorenzo F. Sempere
| MicroRNA as Biomarkers in Cancer Diagnostics and Therapy / Lorenzo F. Sempere |
| Autore | Sempere Lorenzo F |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (166 p.) |
| Soggetto topico | MicroRNAs |
| Soggetto non controllato |
leukemia
cell lines hepatitis B virus long non coding RNA normalization of miRNA expression in RT-qPCR children colorectal review bevacizumab tumor budding cells oral cancer liquid biopsy hepatocellular carcinoma small t-antigen colorectal cancer protein-miRNA complex biomarkers biomarker interleukin-1? tissue analysis miRNAs T-cell acute lymphoblastic leukemia (T-ALL) leukoplakia inflammation exosomes circulating free DNA hepatitis C virus miRNA miR-21 extracellular microRNA endogenous controls lymphoma confocal slide scanning microscopy early diagnosis reference genes large T-antigen microRNA miRNA (microRNA) cancer TNF-? plasma |
| ISBN |
9783039212507
3039212508 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346847003321 |
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Sempere Lorenzo F
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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mTOR in Human Diseases / Olivier Dormond
| mTOR in Human Diseases / Olivier Dormond |
| Autore | Dormond Olivier |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
primary cilia
neurodegeneration nutrient sensor PI3K transcriptomics phosphorylation metabolic reprogramming autophagy Alzheimer's disease rapalogs liver angiogenesis mTOR complex MBSCs advanced biliary tract cancers Medulloblastoma epithelial to mesenchymal transition AMPK p70S6K lipid metabolism thyroid cancer sodium iodide symporter (NIS)/SLC5A5 male fertility anesthesia illumina mTOR inhibitor miRNA Hutchinson-Gilford progeria syndrome (HGPS) eIFs Emery-Dreifuss muscular dystrophy (EDMD) glucose AKT oral cavity squamous cell carcinoma (OSCC) glucose and lipid metabolism cellular signaling aging tumor microenvironment rapamycin leukemia chloral hydrate rapalogues schizophrenia T-cell acute lymphoblastic leukemia senescence lamin A/C neurotoxicity neurodevelopment inhibitor methamphetamine pulmonary fibrosis mTOR mTOR inhibitors combination therapy proteolysis fluid shear stress tumour cachexia biomarkers synapse gluconeogenesis mTOR signal pathway Sertoli cells immunosenescence miRNome protein aggregation senolytics metabolism NGS mTORC2 mTORC1 metabolic diseases IonTorrent apoptosis dopamine receptor nocodazole microenvironment everolimus acute myeloid leukemia immunotherapy spermatogenesis bone remodeling signalling targeted therapy ageing therapy NVP-BEZ235 fructose physical activity laminopathies MC3T3-E1 cells cell signaling microRNA cancer lipolysis melatonin Parkinson's disease |
| ISBN |
9783039210619
3039210610 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684303321 |
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Dormond Olivier
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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