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Bovine Viral Diarrhea Virus and Related Pestiviruses
| Bovine Viral Diarrhea Virus and Related Pestiviruses |
| Autore | Bielefeldt-Ohmann Helle |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (290 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Linda virus
serological profile virus neutralization assay virus pathogenicity humoral immune response pestivirus pig APPV phylogenetic analysis Italy bvdv epidemiology reindeer border disease virus Norway Pestivirus BVDV CD46 life cell imaging attachment surface transport experimental infection natural infection pigs bovine viral diarrhoea virus persistent testicular infection prolonged testicular infection bovine testes semen wild boar ML tree Clade Bungowannah virus pestivirus F ruminant infection foetus porcine real-time PCR serology virology bovine viral diarrhea virus cytopathic BVDV immunosuppression lymphocyte apoptosis monocyte-derived macrophages non-cytopathic BVDV Australia deer prevalence ruminants serosurveillance wildlife disease diarrhea bovine respiratory disease milk production somatic cells count (SCC) reproductive performance BVDV persistent infection fetus thymus immune response flavivirus reverse genetics single round infectious particle bovine viral diarrhea virus (BVDV) escape mutant ERNS adaptation CRISPR knockout MDBK cell entry pestiviruses congenital tremor type A-II persistent infection rangeland beef herds northern Australia atypical porcine pestivirus (APPV) viral persistence congenital tremor swine asymptomatic genomic sequence purifying selection bovine pestiviruses bovine viral diarrhoea vaccination control diagnosis antigenic cross-reactivity |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557301103321 |
Bielefeldt-Ohmann Helle
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting STAT3 and STAT5 in Cancer
| Targeting STAT3 and STAT5 in Cancer |
| Autore | Moriggl Richard |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (578 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
multiple myeloma
STAT3 S3I-1757 nanoparticle CD38 siRNA/RNAi polyethylenimine PEI lipopolyplex siRNA delivery glioma glioblastoma STAT5 AKT ERK1/2 prolactin androgens prostate cancer knockout escape mechanisms stem/progenitor cells cell hierarchy cancer CD4+ T cells CD8+ T cells myeloid cells immune check point hepatitis C virus (HCV) cirrhosis hepatocellular carcinoma (HCC) endoplasmic reticulum (ER) stress oxidative stress (OS) unfolded protein response (UPR) microRNA-122 (miR-122) nuclear factor erythroid 2-related factor 2 (NRF2) signal transducer and activator of transcription 3 (STAT3) hepatocyte nuclear factor 4 alpha (HNF4A) solid cancers cell cycle apoptosis inflammation mitochondria stemness tumor suppression melanoma autoimmune disease immunotherapy tumor-immune cell interactions breast cancer PD-L1 M2 macrophages NK cells STAT3 inhibitor XIII hedging transaction costs dynamic programming risk management post-decision state variable cancer progression cancer-stem cell cytokine therapy resistance metastasis immunosuppression tumor microenvironment proliferation tyrosine kinase 2 JAK family of protein tyrosine kinases signal transducer and activator of transcription cytokine receptor signaling gain-of-function mutation tumorigenesis ADAM17 interleukin-6 trans-signaling epidermal growth factor receptor (EGF-R) shedding metalloprotease tumor necrosis factor alpha (TNFα) inflammation associated cancer colon cancer lung cancer SH2 domain mutations autosomal-dominant hyper IgE syndrome inflammatory hepatocellular adenomas T-cell large granular lymphocytic leukemia T-cell prolymphocytic leukemia growth hormone insensitivity syndrome nuclear pore complex nuclear transport receptors nucleocytoplasmic shuttling targeting tumor-associated macrophages adoptive T cell therapy immune suppression STAT transcription factors JAK STAT T-PLL T-cell leukemia meta-analysis STAT5B signaling small-molecule inhibitors cancer models companion animals comparative oncology pharmacological inhibitor STAT5 signaling chemotherapy resistance myeloid leukemia heat shock proteins chaperones stabilization targeted therapy ovarian cancer hematopoietic cancers therapeutic targeting pharmacological inhibitors mTOR Bone Marrow Failure Syndromes lymphocytes lymphoma T-cells RHOA NGS MPN JAK2 V617F neoplastic stem cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557623503321 |
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Moriggl Richard
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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