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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (606 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
1,2,3-triazole
2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide 3,6-dibromocarbazole 4-(pyridin-4-yloxy)benzamide 5-bromoindole 5-fluorouracil ABCB1 (P-glycoprotein) actin ADME allene amides/esters androgen receptor anti-cancer activity anti-neuroinflammation anti-ovarian cancer anti-tumor anticancer anticancer activity anticancer agent anticancer agents anticancer compounds antimitotic agents antioxidant activity antiproliferative activity antiproliferative agent antitumor antitumor activity apalutamide apoptosis aromatase benzimidazole benzofuran-pyrazole benzofurans beta-lapachone bivalency breast cancer c-Met carbazole cell cycle chemical synthesis chemoresistance chrysin analogues colchiceine colchicine amide colchicine analogs colchicine sulfonamide colon cancer computational docking coumarin crystal structure cyanopyridone cytotoxic activity cytotoxic properties cytotoxicity darolutamide DFT study dihydroartemisinin dihydropyranoindole docking docking studies drug discovery drug resistance E-stereoselective enzalutamide enzyme inhibition estrone derivatives flavonoid flavonoids gemcitabine HDAC inhibitors HeLa HepG2 hydrates hydrazine IGF-1R IL-12 immune modulation indoleamine 2,3-dioxygenase inflammation inhibitor K562 kinase inhibitor MCF-7 MDM2-p53 interaction migration mimetics molecular simulation MOLT-4 multidrug resistance (MDR) reversal N-substituted pyrazoline nanoparticles natural product neuroblastoma NIH3T3 o-nitro-benzyl organosilicon compounds ortho-quinones ovarian cancer overcoming drug resistance P-glycoprotein P-MAPA PARP inhibitor PARP-1 inhibition phenylpyrazolopyrimidine photoactivatable protecting groups PI3Ks PI3Kα inhibitor PI3Kδ inhibitors polyvalency prodrug prostate cancer PROTACs protein degradation protein kinase protein-protein interactions Pyrazole pyrazolopyridine pyridotriazine quinazolin-4(3H)-one quinazolin-4(3H)-thione regioselective salinomycin Schiff base SILA-409 (Alis-409) SILA-421 (Alis-421) Src substituted pyridine synergy synthesis Talazoparib tanshione IIA taxoids thiazolidinone Thienopyrimidine thienopyrimidinone thiocolchicine thiopene thioxotriazopyridine TLR signaling topoisomerase II inhibitor triazolothiadiazine triple-negative breast cancer tryptophan metabolism tubulin inhibitors tumor specificity urea virtual screening xanthones yeast-based assays zampanolide βIII-tubulin |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Boron in Catalysis and Materials Chemistry: A Themed Issue in Honor of Professor Todd B. Marder on the Occasion of His 65th Birthday
| Boron in Catalysis and Materials Chemistry: A Themed Issue in Honor of Professor Todd B. Marder on the Occasion of His 65th Birthday |
| Autore | Kakkar Ashok |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (184 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
1,1,1-tri(boryl)alkanes
1,1,2-tri(boryl)alkanes 1,1,2-tri(boryl)alkenes 1,2,3-tri(boryl)alkanes 1,4-bis(trimethylsilyl)-1,4-diaza-2,5-cyclohexadienes B=N bond boron closo-o-carborane color change conjugated hydrocarbon coupling reaction deboronation dicarbollide electronic structure electrophilic substitution fluorinated ligands fluorosulfanyl group Hirshfield Study IL-10 immobilization of antibodies intramolecular charge transfer iridium isoelectronic molecule kinase inhibitor m-carborane magnetic nanoparticles metallodrug n/a nido-o-carborane opto-electronics organic branches phosphines pre-concentration of antigens quantum chemistry rhodium rotational barrier ruthenium saliva matrix salt-free reduction singlet-triplet gap synthetic applications synthetic approaches tetracoordinated TNF-α π-conjugated materials |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Boron in Catalysis and Materials Chemistry |
| Record Nr. | UNINA-9910557633403321 |
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Kakkar Ashok
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor
| Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor |
| Autore | Holzmann Klaus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (276 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adenocarcinoma of the esophagogastric junction
AKT anticancer astrocytoma autocrine signaling autophagy brain cancer breast cancer cancer cancer signaling cancer-associated fibroblasts coreceptor ERK ERK1/2 estrogen FGF FGF-mediated signaling FGF18 FGF19 FGF2 FGF8 FGFR FGFR1 FGFR2 FGFR2c FGFR4 fibroblast growth factor fibroblast growth factor receptors FRS2 gastric cancer gene regulation GPER HCC HEK293 immunohistochemistry infigratinib sensitivity inhibitors JNK1 keratinocyte kinase inhibitor LY2874455 malignant glioma malignant pleural mesothelioma melanoma membrane proteins monoclonal antibody MTOR n/a negative feedback loop neoadjuvant therapy neurite outgrowth NVP-BGJ398 optogenetics overall survival PC12 phosphorylation prognosis receptor cross-talk receptor kinase resistance review sarcoma seborrheic keratosis serine signaling skin small molecule Sprouty proteins squamous and basal cell carcinoma structure targeted therapy tumor promoter tumor suppressor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Fibroblast Growth Factor Receptor |
| Record Nr. | UNINA-9910557898903321 |
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Holzmann Klaus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Research of Endometrial Pathophysiology / Paola Viganò, Andrea Romano
| Molecular Research of Endometrial Pathophysiology / Paola Viganò, Andrea Romano |
| Autore | Viganò Paola |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (378 p.) |
| Soggetto non controllato |
endometrial stromal cells
endometrial cell uterine cancer regeneration stem cell markers RANK chronic endometritis small RNA sequencing HOXA10 Vitamin D PPP2R1A molecular marker translational research angiogenesis endometriosis oestradiol mtDNA mutations antioxidant response protein phosphatase SMAP circulating tumour cells (CTCs) circulating tumour DNA (ctDNA) estrogen dependent endometrial regeneration mesenchymal stem cells endometrial cancer niche gene expression phosphoinositide 3-kinase lncRNAs mitochondrial biogenesis inflammation preclinical studies miRNA orthoxenograft tight junction proliferation aromatase testosterone CRISPR/Cas9 endometrium developmental pathway PP2A avatar infertility prognosis gene editing kinase inhibitor implantation haploinsufficiency contrast-enhanced CT scan pathway dehydroepiandrosterone (DHEA) CTCF PIK3CB zinc finger ectopic stroma liquid biopsy type II endometrial carcinoma eutopic and ectopic endometrium preclinical models EDN1 uterine aspirate cell contacts tumour suppressor gene pathogenomics mitochondrial dynamics adult stem cells PIK3CA murine models menstrual cycle immunomodulation decidualisation breakdown bioluminescence imaging protein kinase macrophages adherens junction exosomes immunohistochemistry orthotopic xenograft model decidualization p110? deficit of complex I targeted therapy mesenchymal stem cell sulfatase TRP channels personalized medicine mitophagy miR-375 migration microRNA gap junction cancer LGR5 miR-139-5p |
| ISBN |
9783039214969
3039214969 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367752903321 |
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Viganò Paola
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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