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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (594 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
1,2,3-triazole
1,3,4-oxadiazole 3-amino-4'-guanidino 3,4'-bis-guanidino 5-fluoruracil 7-deaza-4'-thioadenosine derivatives acetamide adamantane ADC (antibody-drug conjugate) age alkylated anticancer anticancer activity anticancer agents apoptosis apoptosis induction aromatase inhibitor Bcl-2 inhibitors benzenesulfonamides benzimidazole BRAF breast cancer cancer cancer cell viability cancer vaccine CAR (chimeric antigen receptor) cardiotoxicity carvedilol cell cycle analysis chalcone chalcones colony formation combretastatin A-4 concentration-guided dosing covalent binding CovDock cumulative dose cyclophosphamide cytotoxic activity cytotoxic agents cytotoxicity designed multiple ligand diphenyl ether DNA fragmentation docking doxazosin drug efflux dual inhibitors dual-targeting molecule EGFR ELISA enantioselective synthesis entrectinib exportin-1 gastric adenocarcinoma generic product H1299 HDAC inhibitors HER2 heterocyclic compound histopathology HL-60 HT-29 cells hybrid compounds hybrid molecule hydrazide derivatives imidazoles Imiquimod immunotherapy in vitro in vivo indazole Indole-based analogues inflammation interleukin-6 intramolecular hydrogen bond isolation kidney larotrectinib letrozole MD simulations MDA-MB-231 cells mechanism prediction miR-21 mitoxantrone model informed dosing MTT cytotoxic assay MUC1 MUC16 mucin multi-kinase inhibitor multidrug resistance n/a NaMSA nitrogen scaffolds NTRK nucleoside oxidative stress patent review pemetrexed phenstatin phenyl pyridyl ether physiologically based pharmacokinetics protein kinase inhibitors resin acid solid/lipid nanoparticles sorafenib STAT inhibitors synthesis TDP1 testis thieno[2,3-d][1,2,3]triazine thiourea thymidylate synthase tissue-agnostic Toll-Like Receptor toxicity Trk Trk fusion trypan blue assay tryptophanol tubulin polymerisation inhibitor tumor spheroids tyrosil-DNA-phosphodiesterase 1 urinary bladder USFDA xanthone |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Benefits of Resveratrol Supplementation / María P. Portillo, Alfredo Fernandez-Quintela
| Benefits of Resveratrol Supplementation / María P. Portillo, Alfredo Fernandez-Quintela |
| Autore | Portillo María P |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
polyphenols
?-viniferin leptin resistance p53 kidney energy restriction grape powder extract cytokines phosphorylation obesity energy metabolism metabolic pathways endothelial function polyol pathway antioxidant caloric restriction rat adipose tissue microparticles pathways angiotensin converting enzyme 2 resistance esRAGE interleukins metabolic syndrome dissolution rate thermogenesis streptozotocin bioavailability solubility metabolism renin-angiotensin system microbiota Sirt-1 magnesium dihydroxide hypertrophy metabolic diseases physiological adaption red wine extract lens distribution MTA1 sirtuin inflammation cardiac function rats cisplatin resveratrol mitochondria breast cancer ischemia-reperfusion cardiovascular metabolites gut microbiota prostate cancer performance type 2 diabetes cafeteria diet high-fat high-sucrose diet resistance exercise aging diabetes oxidative stress |
| ISBN |
9783039212767
3039212761 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346854603321 |
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Portillo María P
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomechanical Spectrum of Human Sport Performance
| Biomechanical Spectrum of Human Sport Performance |
| Autore | TAIAR Redha |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (356 p.) |
| Soggetto topico | History of engineering and technology |
| Soggetto non controllato |
3D force modeling
3D motion analysis acceleration ankle injury anterior cruciate ligament anthropometric variables applied science in musculoskeletal disorders artistic gymnastics assessment automation balance ballet dancers barefoot basketball shoe Berlin Questionnaire biomechanics blood flow velocity center of mass chronic ankle instability comfort perception contact force modeling deep learning drop jump dynamics reconstruction Epworth Sleepiness Scale evaluation exercise flexibility flight time foot loading foot morphology football footwear forefoot functional Gait ground reaction forces H/Q ratio hamstring-to-quadriceps ratio Heel human behavior individualized training injury in sport injury prevention injury risk isometric jump throwing ability jumping kidney landing locomotion lower limb machine learning maneuver measurement acquisitions and techniques mechanical analyses of sports mechanical vibration metabolic syndrome minimalist index modeling and simulation in sport science movement movement screen multiscale entropy analysis muscle strength musculoskeletal pain neuromuscular activation neuromuscular training OpenPose optical flow optimal control orthosis overhead patellofemoral contact force patellofemoral contact stress patellofemoral joint pain syndrome performance peritoneal dialysis photoplethysmography physical fitness physical training intensity Pittsburgh Sleep Quality Index plantar pressure posture stability quality of life quantitative biomechanical parameters racket range of motion of the knees reliability robot-assisted training robotic therapy rowing biomechanics rowing simulator running screen self-motion perception signal complexity skin temperature slackline balancing sleep quality sport medicine sports engineering sports training stabilometry strength strength abilities strength and conditioning stroke subject-specific modeling surface electromyographic pattern swimming swing technique tendon based parallel robot tensile strength test texture analysis therapeutic exercises toes function torque traditional Chinese medicine training training of experts transversal vibration control treadmill running TUG two-dimensional video analysis type 2 diabetes mellitus Type 2 diabetes mellitus validity velocity vertical jump vibration virtual reality virtual reality simulator visual speed perception wavelet transform whole body vibration exercise whole-body vibration exercise work related neck pain young athletes |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557497903321 |
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TAIAR Redha
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular and Molecular Mechanisms of Nephropathic Cystinosis
| Cellular and Molecular Mechanisms of Nephropathic Cystinosis |
| Autore | Levtchenko Elena N |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (230 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
3-dimensional models
apoptosis arterial spin labelling autophagy azoospermia biomarkers bone bone-muscle wasting CD34+ hematopoietic stem and progenitor cells cell and animal models cell model central nervous system chitotriosidase clinical course clinical trial cortical atrophy CTNS-pathogenic variants cysteamine cystine cystine blood level cystinosis disulfiram endocytosis endolysosome epithelial cell differentiation fertility fibroblast growth factor 23 fractures galectin-3 gene therapy genotype histopathology history hollow fiber membrane homeostasis hypogonadism infantile nephropathic cystinosis inflammasome interleukins investigational new drug application kidney kidney progenitors kidney proximal tubule leptin lysosomal storage disease lysosomal storage diseases lysosomal storage disorder macrophages mice mitochondrial distress mouse model nephropathic cystinosis newborn screening newborn screening for cystinosis novel therapies osteoclast osteoclasts pre-clinical studies programmed cell death proximal tubular cells sclerostin therapeutic monitoring treatment strategies for cystinosis zebrafish |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585941103321 |
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Levtchenko Elena N
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chronic Kidney Disease: Underlying Molecular Mechanisms
| Chronic Kidney Disease: Underlying Molecular Mechanisms |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2023 |
| Descrizione fisica | 1 online resource (216 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
adipose tissue browning
arsenic biomarkers cachexia cadmium cellular injury children chronic kidney disease CKD developmental origins of health and disease (DOHaD) end-stage renal disease (ESRD) exercise fibrosis FSGS growth hormone gut microbiota heavy metals hypertension inflammation kidney lipolysis lymphatics Marinobufagenin (MBG) mass spectrometry MCD mercury muscle function muscle mass n/a nervous and immune systems NKCC1 transporter NZO mice oxidative stress podocyte dysfunction prebiotics probiotics reactive oxygen species (ROS) SH045 short-chain fatty acids skeletal muscle wasting sodium TNF-alpha TNFR trimethylamine-N-oxide TRPC6 uremic toxins urine proteome UUO |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Chronic Kidney Disease |
| Record Nr. | UNINA-9910743274103321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Immunohistochemical Expression
| Immunohistochemical Expression |
| Autore | Caltabiano Rosario |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (168 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
ABCB5
c-kit carcinogenesis chaperonopathies cytokeratin DEN differential diagnosis EGCG enteric nervous system excretion fraction of uric acid follicular adenoma follicular carcinoma heart Hsp27 Hsp60 Hsp70 Hsp90 human embryonal/fetal tissues hypouricemia immunohistochemistry inflammation initial lymphatics kidney liver macroH2A matrix metalloproteinases megacystis metastasis molecular chaperone n/a neoplastic tissue NGAL outcome and prognosis oxidative stress PDGFR pericardium prognosis prognostic factor prostate cancer SLC22A12 temporomandibular joint temporomandibular joint disorder thyroid training exercise ultra-structural changes URAT1 uric acid transporters urinary tract malformations uveal melanoma VDR Vitamin D WT1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557380403321 |
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Caltabiano Rosario
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Kidney Inflammation, Injury and Regeneration
| Kidney Inflammation, Injury and Regeneration |
| Autore | Koch Benjamin |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (496 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
2-kidney-1-clip
2k1c acute and chronic kidney disease acute kidney failure acute kidney injury AKI allograft rejection alport syndrome apoptosis arachidonic acid B-cell attracting chemokine biomarkers C-reactive protein cAMP Regulatory Element Binding Protein (CREB) chemerin chronic kidney disease chronic kidney disease (CKD) chronic kidney injury Class IIa Histone Deacetylases (HDAC) CmklR1 conditioned medium cPLA2 and COX-2 CREB Regulated Transcriptional Coactivators (CRTC) CXCL13 cyclooxygenase cytochrome P450 cytotoxicity dapagliflozin diabetes mellitus diabetic kidney disease diabetic kidney diseases diabetic nephropathy diagnostics differentiation DSS-colitis empagliflozin endotoxemia endotoxemia-induced oliguric kidney injury epithelial cells exosome exosomes extracellular vesicles Farnesiferol B fibrosis focal segmental glomerulosclerosis G-protein-coupled bile acid receptor (TGR5) genotype glomerular basement membrane glomerular damage glomerular filtration barrier (GFB) glomerular injury glomerulus GLP-1 receptor agonists haem hematuria hypertension IgA nephropathy IL-18 inflammation inflammatory bowel disease (IBD) inflammatory maker injury interleukin-6 ischemia-reperfusion ischemia/reperfusion injury kidney kidney inflammation kidney injury kidney proximal tubule kidney transplantation KIT assay KIT-IgA score lipoxygenase lncRNA long non-coding RNA long non-coding RNAs LPS-binding protein lysophosphatidic acid lysophosphatidic acid receptor mesenchymal stem cell mesenchymal stem cells mesenchymal stromal cells mesodermal stem cell microRNA microRNAs miRNA modified-MSCs modifier gene molecular mechanisms molecular signaling myofibroblast n/a natural products necrosis nephrin niches NLRP3 inflammasome non-coding RNAs noninvasive Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-?B) obese kidney fibrosis omega-3 fatty acid oxidative stress papilla pericyte pigment nephropathy podocin podocyte polymorphism polyploidization polyunsaturated fatty acids prediction proximal tubule regulated necrosis renal cell carcinoma renal fibrosis renal inflammation renal injury renal ischemia-reperfusion renal progenitors renal stem cells renal tubular cells renovascular hypertension rhabdomyolysis ROS Salt Inducible Kinase (SIK) scattered tubular cells SGLT2 inhibitors signal transduction signaling cascade slit diaphragm stem cell T cell-mediated rejection Taiwan therapeutic target therapeutics targets Thy1.1 nephritis transcription tubular injury type I collagen type IV collagen type V collagen xanthine oxidase |
| ISBN | 3-03928-539-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404091203321 |
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Koch Benjamin
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Anti-inflammatory and Antioxidant Agents 2021
| Marine Anti-inflammatory and Antioxidant Agents 2021 |
| Autore | Degl'Innocenti Donatella |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (172 p.) |
| Soggetto topico |
Medicine and Nursing
Pharmacology |
| Soggetto non controllato |
acute kidney injury
acute liver injury algal biome antioxidant apoptosis astaxanthin bioactive entities bioactive peptide blue mussel C-phycoerythrin cytoprotective D-galactose dendritic cells endoplasmic reticulum stress endothelial dysfunction engineered cues ferroptosis fucoxanthin hormone immune dysfunction inflammation inflammatory bowel disease kidney lipopolysaccharide mercury microalgae microRNA n/a natural products oxidative stress oyster oyster peptides peptide Phormidium persicinum polysaccharide polysaccharides pyroptosis RAW 264.7 sepsis spermatogenesis testis therapeutic attributes Tisochrysis lutea transcriptome mining Ulva lactuca zooplankton |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566461803321 |
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Degl'Innocenti Donatella
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Basis of Cardiovascular Diseases : : Implications of Natriuretic Peptides / / Speranza Rubattu, Massimo Volpe
| Molecular Basis of Cardiovascular Diseases : : Implications of Natriuretic Peptides / / Speranza Rubattu, Massimo Volpe |
| Autore | Rubattu Speranza |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (212 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
postmortem biochemistry
medulla animal models remodeling BNP PCSK9 guanylyl cyclase/natriuretic peptide receptor-A cardiorenal syndrome forensic medicine preserved ejection fraction kidney renin-angiotensin-aldosterone system atrial fibrillation vasopressor congestive heart failure atrial natriuretic peptide gene-knockout obesity heart failure angiogenesis adipose tissue vascular LDL receptor metabolic syndrome linkage analysis cardiometabolic disease cardiomyocyte cardiac dysfunction cardiac hypertrophy insulin lipid metabolism cGMP Idiopathic Pulmonary Arterial Hypertension (IPAH) Natriuretic Peptide Clearance Receptor (NPR-C) signaling gene-duplication renin–angiotensin system natriuretic peptides angiotensin receptor–neprilysin inhibitor cardiac remodelling ARNi NT-proBNP inflammation pulmonary arterial hypertension vascular homeostasis endothelial cell Atrial Natriuretic peptide natriuretic peptide vasodilator stroke genetic variants arterial hypertension fibroblast MANP hypertension guanylyl cyclase receptor A |
| ISBN |
9783039215836
3039215833 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367751403321 |
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Rubattu Speranza
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular mechanisms of body water homeostasis / / Carolyn M. Ecelbarger, Dharmendra Kumar Chaudhary, Hwal Lee, Swasti Tiwari
| Molecular mechanisms of body water homeostasis / / Carolyn M. Ecelbarger, Dharmendra Kumar Chaudhary, Hwal Lee, Swasti Tiwari |
| Autore | Ecelbarger Carolyn M. |
| Pubbl/distr/stampa | [San Rafael, California] : , : Morgan & Claypool, , 2017 |
| Descrizione fisica | 1 online resource (112 pages) : color illustrations |
| Disciplina | 572.3 |
| Collana | Colloquium series on integrated systems physiology |
| Soggetto topico |
Osmoregulation
Water in the body Body Water |
| Soggetto non controllato |
water homeostasis
total body water kidney hydration aquaporin diabetes insipidus hyponatremia vasopressin osmolality |
| ISBN | 1-61504-733-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
1. Water, water everywhere -- 1.1 Chapter overview -- 1.2 Body water composition -- 1.2.1 Changes in water homeostasis over the lifespan -- 1.2.2 Body water intake requirements -- 1.3 Measurement of total body water (TBW) -- 1.3.1 Body water compartmentalization -- 1.4 Dehydration -- 1.4.1 Exercise and water requirements -- 1.5 Environmental modulators of body water composition -- 1.5.1 High altitude -- 1.5.2 Extremes in temperature or humidity -- 1.5.3 Dietary alterations --
2. The brain, AVP, and water balance -- 2.1 Chapter overview -- 2.2 The brain -- 2.3 Vasopressin and related neuropeptides -- 2.3.1 Regulation of vasopressin production and release -- 2.4 Vasopressin receptors -- 2.4.1 Receptor cloning -- 2.4.2 Receptor activation and signaling -- 2.4.3 Receptor localization -- 2.5 Vasopressin actions -- 2.5.1 Vasopressin and glomerular filtration rate (GFR) -- 2.5.2 Vasopressin and blood pressure control -- 2.5.2.1 AVPR2 are coupled to nitric oxide generation -- 2.5.2.2 Hypertension may correlate with urinary concentrating ability -- 3. Renal control of water reabsorption -- 3.1 Chapter overview -- 3.2 Blood filtration -- 3.3 The countercurrent multiplier mechanism -- 3.3.1 The Na-K-2Cl cotransporter (NKCC2) -- 3.3.2 Gradient in the inner medulla -- 3.4 The collecting duct -- 3.5 Urea transporters -- 3.6 Renal aquaporins -- 3.6.1 Aquaporin 1 -- 3.6.2 Aquaporin 2 -- 3.6.2.1 Short-term AQP2 regulation -- 3.6.2.2 Long-term AQP2 regulation -- 3.6.2.3 Regulators of AQP2 -- 3.6.3 Aquaporins 3 and 4 -- 3.6.4 Other aquaporins -- 4. Hyponatremia -- 4.1 Chapter overview -- 4.2 Causes and forms of hyponatremia -- 4.3 Hyponatremia and the brain -- 4.4 Hyponatremia and bone health -- 4.5 The syndrome of inappropriate antidiuretic hormone (SIADH) -- 4.5.1 Exercise-induced hyponatremia -- 4.6 Vasopressin escape and molecular mechanismS -- 4.7 Therapies/interventions -- 5. Diabetes insipidus -- 5.1 Chapter overview -- 5.2 Central diabetes insipidus (CDI) -- 5.3 Nephrogenic diabetes insipidus (NDI) -- 5.3.1 Mutations in the vasopressin V2 receptor -- 5.3.2 Mutations in AQP2 -- 5.4 Acquired NDI -- 5.5 Treatments for DI -- 6. Additional pathophysiological states associated with impaired water balance -- 6.1 Chapter overview -- 6.2 Heart failure -- 6.3 Hypertension -- 6.4 Cirrhosis of the liver -- 6.5 Compulsive water drinking -- 6.6 Burn injuries -- 6.7 Medications that alter fluid dynamics -- 6.7.1 Diuretics -- 6.7.2 Aquaretics -- 6.7.3 Peroxisome proliferator-activated receptor, subtype [gamma] (PPAR [gamma]) agonists -- References -- Author biographies. |
| Record Nr. | UNINA-9910153635703321 |
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Ecelbarger Carolyn M.
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| [San Rafael, California] : , : Morgan & Claypool, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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