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ABC Transporters in Human Diseases
| ABC Transporters in Human Diseases |
| Autore | Falguières Thomas |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (494 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
ABC transporters
drug action regulatory extension regulatory insertion mechanism of action MRP1 MRP4 breast cancer proliferation migration invasion cAMP ABCG2 ABCB1 blood-brain barrier PET Alzheimer's disease beta-amyloid tariquidar erlotinib ABCG5 ABCG8 ATP-binding cassette transporter cholesterol polar relay sitosterolemia 5' untranslated region cis-acting elements ABCA subfamily bioinformatics ABC transporter therapy response disease-free survival next-generation sequencing competitive allele-specific PCR P-glycoprotein amyloid-beta neuron SK-N-SH gene therapy AAV PFIC BSEP ABCB11 bile salts intrahepatic cholestasis chaperones PFIC2 BRIC ATP-binding cassette transporter A1 (ABCA1) cholesterol homeostasis reverse cholesterol transport HDL-C dyslipidemia type 2 diabetes microparticles ABCG2 genotype clinico-genetic analysis ethnic specificity genetic variations precision medicine rare variant Roma serum uric acid SUA-lowering therapy urate transporter bile secretion ABCB4 ABCC2 ABCG5/G8 molecular partners phytosterol xenosterol atherosclerosis gall stone ABC transporter ABC (ATP-binding cassette) transporters multidrug resistance transport trafficking urate mutations polymorphisms ABCC6 TNAP NT5E Pseudoxanthoma elasticum (PXE) cancer membrane protein functional divergence calcification pseudoxanthoma elasticum generalized arterial calcification of infancy pyrophosphate therapies ABCA7 phagocytosis Aβ peptides yeast multidrug transporter anticancer antifungal resistance mechanism peroxisome adrenoleukodystrophy fatty acids gout early-onset gout hyperuricemia uric acid BCRP single nucleotide polymorphism SNP homology modeling substrate-binding site cellular ATP efflux mutagenesis intracellular traffic MDR3 phosphatidylcholine RAB GTPase taxol drug transport |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674029103321 |
Falguières Thomas
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (528 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
melanoma
invasion WNT5A MARCKS phosphorylation MANS peptide nanoparticles cell therapy tumor microenvironment sex/gender sex-hormones immunity microRNAs immunotherapy BRAF-mutant melanoma BRAF inhibitor mechanism of action targeted therapy tumour microenvironment plasmacytoid dendritic cells lactate dehydrogenase TLR interferon CXCL10 TPC2 HIPPO SOCE metastasis essential oils angiogenesis apoptosis uveal melanoma (UM) metastatic uveal melanoma (mUM) prognostication adjuvant therapy metastatic therapy metastatic dormancy liver-directed-therapies targeted-therapy combined therapy protein tyrosine phosphatase PTPs inhibitors melanoma immune infiltrate BRAF inhibitors microenvironment resistance therapy therapeutic resistance exosomes extracellular vesicles diagnosis prognosis ctDNA liquid biopsy prediction patient stratification BRAF arthralgia rheumatoid arthritis carbonic anhydrase hedgehog cyclopamine small molecules acetazolamide motility metalloproteinases FAK cancer mucosal melanoma nivolumab pembrolizumab ipilimumab radiotherapy cholinergic system acetylcholine muscarinic receptors nicotinic receptors melanoma metastasis ShcD adaptor protein amoeboid motility Rac1 DOCK4 melanoma PDX target therapy cancer stem cells slow cycling phenotype drug resistance OXPHOS lipid metabolism cancer associated fibroblast melanomagenesis biomarkers checkpoint inhibitor PD-1 melanoma markers cytokines machine learning Support Vector Machine principal component analysis BCL2L10 STAT3 cytotoxicity survival ABT-737 Bcl-2 family ML258 HuR MITF metastases siRNA |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
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Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products
| Antitumoral Properties of Natural Products |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (344 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557419703321 |
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Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products : Volume 2
| Antitumoral Properties of Natural Products : Volume 2 |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antitumoral Properties of Natural Products |
| Record Nr. | UNINA-9910557531303321 |
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Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Arthropod Interactions and Responses to Disturbance in a Changing World
| Arthropod Interactions and Responses to Disturbance in a Changing World |
| Autore | Murphy Shannon M |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (239 p.) |
| Soggetto topico |
Science: general issues
Ecological science, the Biosphere |
| Soggetto non controllato |
disturbance
global change species interactions land-use change wildfire climate range expansions invasion |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557448403321 |
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Murphy Shannon M
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chinese capitalists in Japan's new order [[electronic resource] ] : the occupied lower Yangzi, 1937-1945 / / Parks M. Coble
| Chinese capitalists in Japan's new order [[electronic resource] ] : the occupied lower Yangzi, 1937-1945 / / Parks M. Coble |
| Autore | Coble Parks M. <1946-> |
| Pubbl/distr/stampa | Berkeley, : University of California Press, c2003 |
| Descrizione fisica | 1 online resource (316 p.) |
| Disciplina | 330.951/132042 |
| Soggetto topico | Sino-Japanese War, 1937-1945 - Economic aspects - China - Shanghai |
| Soggetto non controllato |
battle of shanghai
beijing business culture business capitalism central china changzhou china chinese businessmen chinese corporations chinese history collaboration colonialism confucian capitalism corporate culture corporation empire entrepreneur family business government regulation guanxi historical memory invasion japan japanese imperialism military nanjing nationalist army nonfiction occupation rebellion regime resistance wang jingwei war world war two ww2 yangzi |
| ISBN |
9786612356643
1-282-35664-X 0-520-92829-6 1-59734-533-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Surviving the fall of Shanghai -- Japan's new order -- Establishing control : the North China and Central China Development companies -- Puppet governments and Chinese capitalists -- Individual firms and the war experience -- The Rong family industrial enterprises and the war -- Textile and consumer industries in the war era : beyond the Rong model -- Chemical and match industrialists -- China's rubber industry. |
| Record Nr. | UNINA-9910780246903321 |
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Coble Parks M. <1946->
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| Berkeley, : University of California Press, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chinese capitalists in Japan's new order [[electronic resource] ] : the occupied lower Yangzi, 1937-1945 / / Parks M. Coble
| Chinese capitalists in Japan's new order [[electronic resource] ] : the occupied lower Yangzi, 1937-1945 / / Parks M. Coble |
| Autore | Coble Parks M. <1946-> |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Berkeley, : University of California Press, c2003 |
| Descrizione fisica | 1 online resource (316 p.) |
| Disciplina | 330.951/132042 |
| Soggetto topico | Sino-Japanese War, 1937-1945 - Economic aspects - China - Shanghai |
| Soggetto non controllato |
battle of shanghai
beijing business culture business capitalism central china changzhou china chinese businessmen chinese corporations chinese history collaboration colonialism confucian capitalism corporate culture corporation empire entrepreneur family business government regulation guanxi historical memory invasion japan japanese imperialism military nanjing nationalist army nonfiction occupation rebellion regime resistance wang jingwei war world war two ww2 yangzi |
| ISBN |
9786612356643
1-282-35664-X 0-520-92829-6 1-59734-533-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Surviving the fall of Shanghai -- Japan's new order -- Establishing control : the North China and Central China Development companies -- Puppet governments and Chinese capitalists -- Individual firms and the war experience -- The Rong family industrial enterprises and the war -- Textile and consumer industries in the war era : beyond the Rong model -- Chemical and match industrialists -- China's rubber industry. |
| Record Nr. | UNINA-9910822188303321 |
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Coble Parks M. <1946->
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| Berkeley, : University of California Press, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diagnostic, Prognostic and Predictive Biological Markers in Bladder Cancer - Illumination of a Vision 2.0
| Diagnostic, Prognostic and Predictive Biological Markers in Bladder Cancer - Illumination of a Vision 2.0 |
| Autore | Ecke Thorsten |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (240 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Metallothionein
urothelium urothelial cancer cadmium exposure zinc transporter bladder TAGLN F-actin PTEN p53 tumorigenesis proliferation invasion TERT promoter mutations FGFR3 non muscle invasive bladder cancer BCG therapy bladder cancer JAK-STAT pathway combination therapy oncolytic adenovirus virotherapy STAT3/5 inhibitor JAK inhibitor XVir-N-31 bladder cancer detection urinary biomarkers DNA methylation ECRG4 ITIH5 biomarker cancer grade metabolomics MS NMR biomarkers tumor markers prognosis heparanase syndecan-1 heparan sulfate proteoglycans (HSPGs) urothelial carcinoma miRNA quantitative PCR tumor marker voided urine cytology KDM7A histone demethylase TC-E 5002 androgen receptor drug resistance non-invasive detection telomerase somatic mutations TERT promoter region muscle-invasive bladder cancer chemotherapy immunotherapy personalized medicine predictive biomarker survivin BIRC5 macrophage KRT20 ERBB2 MIBC prediction RT-qPCR adjuvant chemotherapy survival |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557142003321 |
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Ecke Thorsten
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The emancipation of writing [[electronic resource] ] : German civil society in the making, 1790's-1820's / / Ian F. McNeely
| The emancipation of writing [[electronic resource] ] : German civil society in the making, 1790's-1820's / / Ian F. McNeely |
| Autore | McNeely Ian F. <1971-> |
| Pubbl/distr/stampa | Berkeley, : University of California Press, c2003 |
| Descrizione fisica | 1 online resource (348 p.) |
| Disciplina | 300/.943/09033 |
| Collana | Studies on the history of society and culture |
| Soggetto topico |
Bureaucracy - Germany - History
Written communication - Germany - History Civil society - Germany - History |
| Soggetto non controllato |
black forest
bureaucracy citizenship civic culture civil society duchy of wurttemberg europe foucault free market free press french revolution german history german identity german southwest germany government habermas history identity intelligenzblatt invasion military modes of power napoleon nation nonfiction occupation resistance schorndorf schreiber scribes social networks state authority state power war welzheim writing practices writing wurttemberg |
| ISBN |
1-283-27705-0
9786613277053 0-520-92852-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Front matter -- Contents -- Illustrations -- Acknowledgments -- Introduction -- 1. The Civic Landscape -- 2. The Tutelage of the Scribes -- 3. The Black Forest Cahier -- 4. Constitutional Fetishism -- 5. Transcending "Textual Serfdom" -- 6. Reading, Writing, and Reform -- 7. Cataloging the Social World -- 8. The Intelligence Gazettes -- Conclusion -- Glossary -- Abbreviations -- Notes -- Sources -- Index |
| Record Nr. | UNINA-9910780250803321 |
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McNeely Ian F. <1971->
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| Berkeley, : University of California Press, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The emancipation of writing [[electronic resource] ] : German civil society in the making, 1790's-1820's / / Ian F. McNeely
| The emancipation of writing [[electronic resource] ] : German civil society in the making, 1790's-1820's / / Ian F. McNeely |
| Autore | McNeely Ian F. <1971-> |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Berkeley, : University of California Press, c2003 |
| Descrizione fisica | 1 online resource (348 p.) |
| Disciplina | 300/.943/09033 |
| Collana | Studies on the history of society and culture |
| Soggetto topico |
Bureaucracy - Germany - History
Written communication - Germany - History Civil society - Germany - History |
| Soggetto non controllato |
black forest
bureaucracy citizenship civic culture civil society duchy of wurttemberg europe foucault free market free press french revolution german history german identity german southwest germany government habermas history identity intelligenzblatt invasion military modes of power napoleon nation nonfiction occupation resistance schorndorf schreiber scribes social networks state authority state power war welzheim writing practices writing wurttemberg |
| ISBN |
1-283-27705-0
9786613277053 0-520-92852-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Front matter -- Contents -- Illustrations -- Acknowledgments -- Introduction -- 1. The Civic Landscape -- 2. The Tutelage of the Scribes -- 3. The Black Forest Cahier -- 4. Constitutional Fetishism -- 5. Transcending "Textual Serfdom" -- 6. Reading, Writing, and Reform -- 7. Cataloging the Social World -- 8. The Intelligence Gazettes -- Conclusion -- Glossary -- Abbreviations -- Notes -- Sources -- Index |
| Record Nr. | UNINA-9910821454403321 |
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McNeely Ian F. <1971->
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| Berkeley, : University of California Press, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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