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Intrinsically Disordered Proteins and Chronic Diseases
| Intrinsically Disordered Proteins and Chronic Diseases |
| Autore | Kulkarni Prakash |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (224 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
binding mechanism
coactivators conformational ensemble conformational plasticity COR15A depletion interaction diffusion disease-related proteins drug design dynamic configuration electrostatics entropic force extremely fuzzy complex free energy landscape functional segments fuzzy interactions gene regulation glucocorticoid receptor IDP intrinsic disordered protein intrinsically disordered intrinsically disordered protein intrinsically disordered proteins intrinsically disordered regions Kinase-inducible domain interacting domain kinetics Late embryogenesis abundant liquid-liquid phase separation low-complexity sequences membraneless organelles microtubule associated protein microtubules molecular dynamics molecular modelling mouse double minute 2 mouse double minute 4 n/a nuclear magnetic resonance Nuclear magnetic resonance optical tweezer order-disorder transition PAGE4 phosphomimetics phosphorylation protein complementation assays protein diffusion protein interaction protein structure prediction protein-protein interaction replica exchange molecular dynamics split-GFP reassembly subcellular location tau tau-microtubule association transactivation activity transient secondary structure Trifluoroethanol tumor protein p53 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557746903321 |
Kulkarni Prakash
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Amazing World of IDPs in Human Diseases
| The Amazing World of IDPs in Human Diseases |
| Autore | Monti Simona Maria |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (196 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
actin
alpha-synuclein cancer circular dichroism cytoskeleton remodeling de novo EPR spectroscopy evolutionary origin flexibility fluorescence gene duplications human disease importin interface core and rim intrinsically disordered protein intrinsically disordered protein (IDP) intrinsically disordered proteins intrinsically disordered regions isothermal titration calorimetry isothermal titration calorimetry (ITC) linear motifs Methyl-CpG-binding protein 2 (MeCP2) molecular docking molecular recognition features n/a NADH-26S proteasome neurodegenerative diseases NMR nuclear magnetic resonance (NMR) nuclear protein 1 (NPR1) peptide pre-structured motifs (PreSMos) proline-rich motif protein degradation protein misfolding protein stability protein structural dynamics protein-DNA interaction protein-ligand interaction protein-protein interactions proteostasis Rett syndrome secondary structure propensity SH3 domain single nucleotide variants site-directed spin labeling ubiquitin independent degradation ubiquitin-proteasome system WASp interacting protein |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557334303321 |
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Monti Simona Maria
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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