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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (418 p.) |
| Soggetto topico | Biotechnology |
| Soggetto non controllato |
activation induced deaminase
AID/APOBEC alternative splicing anti-cancer artificial intelligence bioinformatics Bioinformatics tool biomarker discovery biomarker signature biomarkers biostatistics brain brain metastases breast cancer breast cancer detection breast cancer prognosis Bufadienolide-like chemicals cancer cancer biomarker cancer biomarkers cancer CRISPR cancer modeling cancer prognosis cancer treatment cancer-related pathways cell-free DNA chemotherapy circulating tumor DNA (ctDNA) classification clinical/environmental factors colorectal cancer comorbidity score Computational Immunology concatenated deep feature copy number aberration copy number variation curation curative surgery datasets decision support systems deep learning denoising autoencoders differential gene expression analysis diseases genes DNA DNA sequence profile drug resistance epigenetics erlotinib estrogen extreme learning false discovery rate feature extraction and interpretation feature selection firehose functional analysis gefitinib gene expression analysis gene inactivation biomarkers gene loss biomarkers gene signature extraction genomic instability GEO DataSets head and neck cancer health strengthening herb hierarchical clustering analysis high-throughput analysis histopathological imaging histopathological imaging features HNSCC hormone sensitive cancers HP hTERT imaging independent prognostic power interaction intratumor heterogeneity knockoffs KRAS mutation locoregionally advanced machine learning meta-analysis methylation microarray miRNA miRNAs mitochondrial metabolism mixture of normal distributions molecular mechanism molecular subtypes Monte Carlo mortality multiple-biomarkers mutable motif mutation Neoantigen Prediction network analysis Network Analysis network pharmacology network target neurological disorders next generation sequencing observed survival interval omics omics profiles oral cancer ovarian cancer overall survival pancreatic cancer pathophysiology PD-L1 precision medicine predictive model protein R package RNA self-organizing map single-biomarkers single-cell sequencing skin cutaneous melanoma somatic mutation StAR steroidogenic enzymes survival analysis TCGA TCGA mining telomerase telomeres The Cancer Genome Atlas traditional Chinese medicine transcriptional signatures treatment de-escalation tumor tumor infiltrating lymphocytes tumor microenvironment variable selection |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metastatic Progression and Tumour Heterogeneity
| Metastatic Progression and Tumour Heterogeneity |
| Autore | Hollande Fred |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (312 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
3D cultures
acidosis ADH angiocrine factor beta-catenin paradox biomechanics breast cancer carbonic anhydrase cell fate cellular heterogeneity circulating tumor cells circulating tumor cells (CTCs) clear cell renal cell carcinoma clonality collective and single-cell migration colon cancer colorectal cancer CTC-clusters DCIS deficient mismatch repair EMT endometrial carcinoma epigenetics epithelial mesenchymal plasticity epithelial-to-mesenchymal transition esophageal squamous cell carcinoma extracellular vesicles gene expression genomics heterogeneity hybrid E/M hyperpolarized 13C MRI immune checkpoints immune microenvironment immunotherapy interstitial pH intra-tumour heterogeneity intratumor heterogeneity lactic acid magnetic resonance imaging mammary gland metaplastic carcinoma metastasis metastatic niche microsatellite instability miRNA expression multisite tumor sampling mutation natural killer cells nuclear medicine organoids pancreatic cancer PET phenotypic plasticity PI3K/AKT pathway plasticity positron emission tomography precision medicine radiomics radiopharmaceuticals review signaling single-cell analysis single-cell RNAseq subclonal diversity SUV target discovery targeted therapy TP53 treatment resistance tumor ecology tumor endothelial cell tumor evolution tumor heterogeneity tumor microenvironment tumor mutation burden uterine carcinosarcoma Wnt signaling |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557105803321 |
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Hollande Fred
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Precision Medicine in Solid Tumors
| Precision Medicine in Solid Tumors |
| Autore | Dey Nandini |
| Descrizione fisica | 1 online resource (304 p.) |
| Soggetto topico |
Medicine and Nursing
Oncology |
| Soggetto non controllato |
adjuvant chemotherapy
anaplastic lymphoma receptor tyrosine kinase breast cancer cancer cancer-associated fibroblasts cfDNA chemotherapy circulating free DNA clinical guideline clonality classification comprehensive genomic profiling CTC ctDNA DDR genes Decision tree digital enrichment driver mutation EGFR mutation EGFR-TKI electronic records epidermal growth factor receptor extent of resection gene panel sequencing glioblastoma prognosis HNSCC immune checkpoint inhibitors immunocytochemistry immunotherapy intratumor heterogeneity laboratory-friendly liquid biopsy molecular barcoding molecular genotyping multiple biopsies n/a new drug development next-generation sequencing next-generation sequencing (NGS) NGS non-small cell lung cancer open data osimertinib outcome overall survival parallel double-detection PARP inhibitors PD-L1 pediatric tumors personalized precision oncology precision medicine presumed germline findings random forest regulatory reform resistance screening sequencing smoking solid cancer strategic therapeutic intervention targeted therapy tDNA thymoma TMB TNBC subtypes triple-negative breast cancer (TNBC) tumor evolution tumor mutational burden tumor profiling test tyrosine kinase inhibitor universal health-care system whole-exome sequencing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595078103321 |
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Dey Nandini
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| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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