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Drug Absorption Studies: In Situ, In Vitro and In Silico Models
| Drug Absorption Studies: In Situ, In Vitro and In Silico Models |
| Autore | Song Im-Sook |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (171 p.) |
| Soggetto topico |
Manufacturing industries
Medicine and Nursing |
| Soggetto non controllato |
acetaminophen-induced hepatotoxicity
amorphous solid dispersion BCS drug classification bioavailability biomedical drug breast cancer resistance protein candesartan Cilexetil catabolism disorder chitosan cinnarizine D-α-Tocopherol polyethylene glycol 1000 succinate (TPGS) dissolution profiles drug-phytochemical interaction endocytosis enoxaparin enzyme extra virgin olive oil hepatic metabolism hydrogel in vivo-in vitro correlation intestinal absorption intestinal permeability kinetics l-phenylalanine ammonia-lyase lipid-based drug delivery system lipid-polymer hybrid nanoparticles lipolysis lipolysis-permeation liver distribution LY335979 meloxicam metabolism microsphere mixed inhibition naftidrofuryl oxalate nanocrystals nasal administration non-sink condition oral oral mucositis P-glycoprotein permeability PermeaPad pH-modulation pharmaceutical availability phenolic compounds phenylketonuria poorly soluble drugs PVPK30 quercetin rebamipide repaglinide secoiridoids silymarin solubility solubility-permeability interplay solubilizer additive spray drying spray-drying unstirred water layer WK-X-34 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Drug Absorption Studies |
| Record Nr. | UNINA-9910557689203321 |
Song Im-Sook
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Impact of Bioactive Peptides on Human Health / Kaustav Majumder
| Impact of Bioactive Peptides on Human Health / Kaustav Majumder |
| Autore | Majumder Kaustav |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (212 p.) |
| Soggetto topico | Food manufacturing & related industries |
| Soggetto non controllato |
which prevent the occurrence of chronic diseases through their impacts on the gastrointestinal
immune bioavailability and the modulation of human nutrition and nervous systems. Further bioactive peptide discoveries are essential for maintaining human health and commercial development in the area of functional foods and nutraceuticals. This Special Issue covers a wide range of research topics specifically on food-derived bioactive proteins and peptides including the in-vitro and in-vivo evaluation of biological activities the effect on chronic diseases Food-derived bioactive peptides or dietary peptides are increasingly becoming recognized as major food compounds for human health promotion intestinal absorption cardiovascular bio-accessibility |
| ISBN |
9783038976219
3038976210 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346667603321 |
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Majumder Kaustav
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Bioactive Peptides : : Structure, Function, and Therapeutic Potential / / Tatiana V. Ovchinnikova
| Marine Bioactive Peptides : : Structure, Function, and Therapeutic Potential / / Tatiana V. Ovchinnikova |
| Autore | Ovchinnikova Tatiana V |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (442 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
cone snail
tilapia animal models BRICHOS domain recombinant peptide calcium absorption plastein reaction antioxidant activity endothelial dysfunction C3a lung cancer invertebrate immunity identification zinc bioavailability NA-inhibitory peptide nuclear magnetic resonance (NMR) review ACE-inhibitory activity intestinal absorption hairtail (Trichiurus japonicas) DU-145 cells peptide crustacean venom duct Kalloconus drug design molecular symmetry arenicin ?-helix APETx2 conotoxins functional diversity docking conotoxin neuraminidase angiotensin II polychaeta influenza virus phylogeny gene expression host defense peptide Perinereis aibuhitensis anti-diabetic activity conopeptides SHRs Chlorella pyrenoidosa protein hydrolysate (CPPH) metastasis Caco-2 cell monolayer Nrf2 caco-2 cells HUVEC PYP15 sea cucumber decapeptide cytotoxic arenicin-1 marine peptides cell proliferation Conus Conus ateralbus self-production of hydrogen peroxide antimicrobial activity molecular dynamics machine learning tachyplesins ion channels gut microbiota Anthopleura anjunae oligopeptide signaling pathways half-fin anchovy hydrolysates NF-?B Chlorella pyrenoidosa protein hydrolysate-calcium chelate (CPPH-Ca) antihypertensive effect QAGLSPVR antimicrobial peptides vasculogenic mimicry antibacterial ?-hairpin innate immunity transcriptome sequencing HIF-1? Gracilariopsis lemaneiformis function ACE-inhibitory peptide complement peptide-zinc complex structure-activity relationship multi-functional peptides cod skin adsorption Maillard reaction products molecular docking antibacterial peptide PI3K/AKT/mTOR signaling pathway Arenicola marina antimicrobial peptide Rana-box acid-sensing ion channel Neptunea arthritica cumingii apoptosis membrane damage proteolytic system toxin polyphemusins computational studies muscle oyster zinc-binding peptide abalone pain relief transport routes cytotoxicity dexamethasone cell death host?microbe relationship anti-LPS factor MMPs protein synthesis structure Pyropia yezoensis peptide cone snails chemical synthesis prostate cancer Ugr 9-1 myotube atrophy |
| ISBN |
9783039215331
3039215337 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367750603321 |
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Ovchinnikova Tatiana V
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Carotenoids
| Marine Carotenoids |
| Autore | Sugawara Tatsuya |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (744 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
acetylcholinesterase
acrosome reaction alcoholic liver disease alcoholic liver injury Alzheimer's disease antheraxanthin anti-angiogenic anti-cancer anti-diabetic anti-inflammatory anti-obesity anti-obesity effect anti-oxidant anti-oxidative activity antibiotics antioxidant antioxidant inflammatory antioxidants antiproliferative effect apo-fucoxanthinone apoptosis ascorbyl palmitate astaxanthin astaxanthin (Asta) astaxanthin production Bangia fuscopurpurea beauty bioactive compounds bioinformatic analysis blue biotechnology Caco-2 canthaxanthin cardioprotective activity carotenoid carotenoid synthesis pathway carotenoids cholera toxin subunit B (CTB) chronic obstructive pulmonary disease cigarette smoke exposure Coelastrum cognitive impairments comparative transcriptome analyses copepod cosmeceuticals dehydro-metabolite disease electrotechnologies Escherichia coli fluridone Franz cell fucoxanthin functional food gene cloning genome-reduced Corynebacterium glutamicum green processing Haematococcus pluvialis halocynthiaxanthin heme oxygenase-1 high through-put screening high-fat diet human papillomavirus 16 (HPV16) hydroxyl radical immune system inflammation intestinal absorption L1 protein lipid metabolism lipid peroxidation lutein lutein-5,6-epoxide lycopene cyclase marine drugs marine microalgae marine microorganisms meso-zeaxanthin metabolic engineering metabolic pathway in vivo metabolism microalgae microwave-assisted extraction mRNA expression mytiloxanthin nanoemulsion nitrogen starvation nonconventional extraction Nrf2 nuclear factor erythroid 2-related factor 2 oxidative stress ozonolysis p38 MAPK Phaeodactylum extract Phaeodactylum tricornutum phytoene PII signaling protein pulsed electric field-assisted extraction Pyropia yezoensis reactive oxygen species red algae red seaweed scopolamine seaweeds singlet oxygen siphonaxanthin spectrophotometry stereochemistry sublingual delivery supercritical fluid extraction synaptic-associated plasticity systematic approach thermal stress Tigriopus TLR4 white adipose tissue zeaxanthin zeinoxanthin α-cryptoxanthin β-carotene hydroxylase β-carotene ketolase |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557148503321 |
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Sugawara Tatsuya
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutraceutical, Nutrition Supplements and Human Health
| Nutraceutical, Nutrition Supplements and Human Health |
| Autore | Siddiqui Rafat A |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (348 p.) |
| Soggetto topico |
Biology, life sciences
Food & society Research & information: general |
| Soggetto non controllato |
16S rDNA
abdominal fat area age-related diseases AKBA antioxidant antiproliferative apoptosis arsenic atherosclerosis aurora kinase A Autism spectrum disorder bacteriocin Bifidobacterium breve B-3 Bifidobacterium breve M-16V bioavailability black mulberry blood glucose BMI body fat mass Boswellia boswellic acid breast cancer cachexia Caco2 cells cancer carbohydrates Carica papaya catechins chorioallantoic membrane assay clinical efficacy coenzyme Q10 (CoQ10) curcumin cytokine cytokines diet supplement Dietary Supplement Label Database dietary supplements feces fenugreek food classification food composition food description FoodEx2 formulated curcumin frankincense functional food GBS graviola green tea extract gut microbiota hepatocellular carcinoma hepatotoxicity herbal dietary supplements infant health inflammation intestinal absorption Lactobacillus salivarius LDL-r-KO mice lupeolic acid metabolic syndrome metabolomics microbiome mitochondria Morus nigra L. muscle mass muscle wasting myoblasts n/a natural products neuroprotection nutraceutical obesity otitis pathological calcification pediatric pentacyclic triterpenic acid pharmacokinetics pharmacological properties physician communication plasma Platycodon grandiflorus root plum pregnancy prevention probiotic probiotics protein hydrolysate protein synthesis proteins quelites skeletal muscles Streptococcus agalactiae supplementation triterpenoid vitamin K vitamin K-dependent proteins weight loss wild rice |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557507803321 |
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Siddiqui Rafat A
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutraceuticals in Human Health
| Nutraceuticals in Human Health |
| Autore | Durazzo Alessandra |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (224 p.) |
| Soggetto topico |
Biology, life sciences
Food & society Research & information: general |
| Soggetto non controllato |
3T3-L1 preadipocytes
Ac-α-tubulin Allium sativum analysis anthocyanins anti-adipogenic effects anti-inflammatory antimicrobial antioxidant antioxidant capacity apigenin apoptosis applications bioactive compounds bioactive polysaccharides biomedical applications biorefinery carotenoid cervical cancer cells chemometrics cherry cholesterol clinical tests copper sulfate cupric ions defatted flour degradation efficacy egg quality emulsifying properties emulsion stability energy homeostasis extraction fatty acids fenugreek seed ferrous ions flavonoids formulation FTIR spectroscopy fulvic acids functional beverage garlic gene expression ginger water grape grape seeds growth inhibition Haugh unit health human health HUVEC intestinal absorption iron linseed luteolin medicinal food medicinal foods mineral nanoparticles nanosystems nutraceuticals obesity oxidative status phenolic compounds Platycodon grandiflorus polyphenols protein concentrate Prunus serotine rat regulation safety saponins soluble protein spirulina yolk yolk color β-carboline alkaloids |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557765703321 |
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Durazzo Alessandra
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Poultry Nutrition
| Poultry Nutrition |
| Autore | Tufarelli Vincenzo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (754 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general Technology, engineering, agriculture |
| Soggetto non controllato |
administration method
Aflatoxin B1 Allium alternative energy source alternative ingredients amino acids anti-fungal antibiotic antibiotics anticoccidials antioxidant antioxidant capacity antioxidant status antiradical activity apoptosis arabinofuranosidases ascorbic acid Aspergillus flavus autophagy bamboo leaf extract bee pollen beneficial effects betaine bilberry leaves biological nano-curcumin bitter taste receptors blood blood biochemical parameters blood chemistry blood constituents blood haematology blood parameter boric acid broiler broiler chicken broiler chickens broilers broilers feeding cadmium Camelina cake Camelina oil carcass cecal microbiota charcoal chicken chickens Chinese yellow-feathered chickens chitooligosaccharide cholesterol cholesterol metabolism chromium clay Clostridium perfringens Cobb E compensatory growth crude protein reduced diet curcumin CuZn-SOD denatonium benzoate DHA diet dietary supplementation digestibility balance digestive enzyme activities digestive function drinking water ducks duodenum egg and meat quality egg production electrophysiology embryonic development emulsifiers energy requirement enrichment enzyme dose essential oils Evans blue dye fatty acid fatty acids feed additive feed additives feed conversion ratio feed intake fertility footpad dermatitis free fatty acids frozen meat genistein ggTas2Rs Glycyrrhiza glabra green tea green tea powder growth growth indices growth performance hatchability health health status heart heat shock proteins heat stress hematological indicator high environmental temperature HMG-CoA housing system HSP70 huainan partridge chicken Hubbard F15 humoral immunity hydrolysable polyphenol IBDV IGF1 IGFBP2 immune function immunity immunoglobulin in ovo injection in vitro indigenous yellow-feathered breed intestinal absorption intestinal health intestinal integrity intestinal morphology intestinal villi intracytoplasmic vacuoles ISA brown kidney L-arginine L-Thr Lactobacillus laying hens laying performance levels licorice lipid peroxidation lipoprotein lipase mannanoligosaccharide meat meat quality medicinal mushrooms metabolism methionine modeling monoglyceride Moringa oleifera multienzymes n/a nanoparticles necrotic enteritis nutrient deposition nutrient requirements nutrient utilization nutrition omega-3 omega-6 organic acids organosulfur compounds oxidative status Partridge Shank chickens pathogen pathogens pekin ducks performance pharmaceutical phospholipids physiological responses phytase phytobiotic phytobiotics phytogenics plasma lipid polyethylene glycol polyphenols polyunsaturated fatty acids pomegranate poultry poultry feeding prebiotics probiotic probiotics production production performance propolis quail red grape pomace waste reduced crude protein residual feed consumption royal jelly Salmonella Salmonella Enteritidis selenium retention selenium sources-levels serum biochemistry slaughter characteristics slow-growing broilers SNP sources soybean isoflavones soybean lecithin strain supplementation TBARs TGFß3 threonine triacylglycerols turkey Ussing chamber vegetable acid oil viral protein 5 mRNA expression vitamin B12 walnut leaves weight gain xylanase zinc oxide zinc utilization |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557422003321 |
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Tufarelli Vincenzo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation
| Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation |
| Autore | Gonzalez-Alvarez Maria Isabel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (238 p.) |
| Soggetto topico |
Manufacturing industries
Medicine and Nursing |
| Soggetto non controllato |
absorption-modifying excipients
BCS class IV drugs BCS drugs bioequivalence biomimetic membrane biopharmaceutics biopharmaceutics classification system Biopharmaceutics Classification System clinical studies colon absorption combined zero- and first-order absorption controlled release drug product DDI disintegration dissolution dissolution test drug absorption drug permeability drug solubility drug solubility/dissolution drug-drug interactions energy intake enteric-coated first-order absorption first-pass effect Franz cell Franz-PAMPA furosemide gastrointestinal gastrointestinal hormone GastroPlus hierarchical support vector regression (HSVR) human colon carcinoma cell layer (Caco-2) ibuprofen ICH in silico modeling in situ perfusion in vitro in vitro in vivo extrapolations intestinal absorption intestinal perfusion intestinal permeability IVIVE location-dependent absorption manometry mechanistic modeling microdevices mucoadhesion nutrient absorption nutrient digestion obesity oral absorption oral drug delivery oral peptide delivery passive drug transport PBBM PBPK permeation enhancers pharmaceutical development pharmacokinetics Phoenix WinNonlin physiologically-based pharmacokinetic (PBPK) modeling postprandial glycaemia pravastatin quality control region of the gut regional intestinal permeability regional/segmental-dependent permeability and absorption route-dependent intestinal metabolism segmental-dependent intestinal permeability segregated flow intestinal model (SFM) shape traditional model (TM) transit compartment absorption model type 2 diabetes zero-order absorption |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Regional Intestinal Drug Absorption |
| Record Nr. | UNINA-9910566462603321 |
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Gonzalez-Alvarez Maria Isabel
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Health Benefits of the Bioactive Compounds in Foods
| The Health Benefits of the Bioactive Compounds in Foods |
| Autore | Jaime Laura |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (234 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
'Cara Cara' juice
ACE-inhibitory activity analysis anti-inflammatory anti-obesity anticancer antimicrobial activities antinausea antiobesity antioxidant antioxidant activity antioxidant potential apitherapy bee pollen beverages bioaccessibility bioactive compounds bioactive peptides bioavailability biologic activity biological activities body composition brewing method calafate juice carotenoid central composite rotatable design content coronavirus disease 2019 COVID-19 cow's milk protein allergy (CMPA) cryoconcentration curcumin degradation dietary interventions donkey colostrum (DC) donkey milk (DM) dried distilled spent grain (DDSG) flavonoid functional food grape pomace grape stem health benefits hydrophilic and lipophilic antioxidant hypertension immunosenescence insulin resistance insulin sensitivity intestinal absorption isolation lean body mass mammal's milk mechanism of action melanoidins metabolic syndrome microbiota milk proteins mineral composition mitochondrial dysfunction muscle muscle wasting nanoparticles phenolic compounds physical performance physicochemical properties phytochemicals polyphenols polysaccharide purification PPARγ pressurized liquid extraction proliferation propolis royal jelly sarcopenia satellite stem cells sensorial analysis side streams valorisation skeletal storage storage time structure sustainable food systems total polyphenols content |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557361603321 |
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Jaime Laura
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transmucosal Absorption Enhancers in the Drug Delivery Field
| Transmucosal Absorption Enhancers in the Drug Delivery Field |
| Autore | Maher Sam |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (406 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
absorption enhancement
absorption enhancer absorption enhancers absorption modifying excipients Aloe vera amino acid amphiphilic polymers and liposome antiepileptic drug antimicrobial peptide biocompatibility studies bioenhancer block copolymers brush border Caco-2 Caco-2 cells cationic functionalization cell-penetrating peptide cell-penetrating peptide (CPP) cervicovaginal tumors chitosan chitosan derivatives claudin clinical trial CNS disorders combined microsphere compound 48/80 confocal laser scanning microscopy cornea curcumin cyclodextrin cytochrome P450 drug absorption enhancer drug administration drug delivery efflux enterocyte epithelial permeability epithelial transport epithelium F-actin FITC-dextran formulation gel gemini surfactant GLP-1 hydrophobization imatinib in situ hydrogel in vivo studies insulin intestinal absorption intestinal delivery intestinal epithelial cells intestinal permeation enhancers KLAL man mast cell activator metabolism mucoadhesion mucoadhesiveness N-dodecyl-?-D-maltoside (DDM) nanocapsules nanocrystals nanomedicine nanoparticle nanoparticles nasal nasal delivery nasal formulation nasal permeability nasal vaccination nose to brain delivery nose to brain transport nose-to-brain ocular conditions ocular delivery ocular drug delivery ophthalmology oral delivery oral macromolecule delivery oral peptides osteoporosis P-glycoprotein penetration enhancer penetration enhancers permeability permeation enhancer permeation enhancers pharmacokinetic interaction pharmacokinetics PN159 polymeric micelles poorly absorbed drug preclinical PTH 1-34 pulmonary quaternization safety salcaprozate sodium sheep simulated intestinal fluid simvastatin small intestine sodium caprate sodium cholate (NaC) sugar-based surfactants teriparatide thermogel system tight junction tight junction modulator tight junctions transepithelial electrical resistance transferrin transmucosal drug delivery transmucosal permeation tryptophan vaccine adjuvant vaginal delivery whole leaf |
| ISBN | 3-03921-849-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910372785603321 |
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Maher Sam
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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