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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (594 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
thymidylate synthase
cytotoxicity 1,2,3-triazole 1,3,4-oxadiazole 5-fluoruracil pemetrexed docking 3,4'-bis-guanidino 3-amino-4'-guanidino diphenyl ether phenyl pyridyl ether intramolecular hydrogen bond cancer cell viability HL-60 BRAF apoptosis thieno[2,3-d][1,2,3]triazine acetamide H1299 HER2 EGFR Bcl-2 inhibitors Indole-based analogues benzimidazole MTT cytotoxic assay cell cycle analysis DNA fragmentation ELISA solid/lipid nanoparticles phenstatin letrozole tubulin polymerisation inhibitor aromatase inhibitor breast cancer hybrid molecule dual-targeting molecule designed multiple ligand NaMSA cyclophosphamide histopathology testis urinary bladder anticancer agents enantioselective synthesis gastric adenocarcinoma tryptophanol concentration-guided dosing model informed dosing physiologically based pharmacokinetics sorafenib tyrosil-DNA-phosphodiesterase 1 adamantane resin acid TDP1 cytotoxic agents apoptosis induction HT-29 cells MDA-MB-231 cells mechanism prediction STAT inhibitors miR-21 hydrazide derivatives nitrogen scaffolds mitoxantrone cardiotoxicity inflammation oxidative stress age cumulative dose Trk NTRK tissue-agnostic larotrectinib entrectinib Trk fusion protein kinase inhibitors USFDA cancer patent review generic product doxazosin MD simulations combretastatin A-4 cytotoxic activity hybrid compounds indazole mucin MUC1 MUC16 immunotherapy cancer vaccine CAR (chimeric antigen receptor) ADC (antibody-drug conjugate) thiourea interleukin-6 trypan blue assay chalcones exportin-1 covalent binding CovDock anticancer activity xanthone in vitro in vivo isolation synthesis heterocyclic compound benzenesulfonamides imidazoles alkylated colony formation tumor spheroids HDAC inhibitors chalcone dual inhibitors carvedilol kidney toxicity 7-deaza-4'-thioadenosine derivatives multi-kinase inhibitor anticancer nucleoside Imiquimod drug efflux multidrug resistance Toll-Like Receptor |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Atherosclerosis : Technologies of Personalized Medicine
| Atherosclerosis : Technologies of Personalized Medicine |
| Autore | Ragino Yuliya I |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (150 p.) |
| Soggetto topico |
Medicine
Cardiovascular medicine |
| Soggetto non controllato |
metalloproteinases
calcification atherosclerosis multiplex assay coronary heart disease aspirin resistance non-sensitivity antiplatelet light transmission aggregometry Plateletworks® familial hypercholesterolemia targeted sequencing technologies multiplex ligation-dependent probe amplification LDLR APOB ABCG5 APOC3 LPL SREBF1 rare variants coronary atherosclerosis ischemic heart disease saturated fatty acids monounsaturated fatty acids polyunsaturated fatty acids oxidative stress superoxide dismutase catalase glutathione peroxidase cumulative LDL-C level prognosis DNA methylation epigenetic age myocardial infarction acute coronary syndrome population nested case-control HAPIEE project HAPIEE study atrial fibrillation arterial hypertension obesity diabetes mellitus aging determinants prevalence Russian population cohort Cox regression analysis adiponectin leptin interleukin-6 epicardial adipose tissue perivascular adipose tissue circulating biochemical markers coronary atherosclerosis presence and severity integrated biomarker (i-BIO) validation visual markers lipoprotein(a) immune cells blood count |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Atherosclerosis |
| Record Nr. | UNINA-9910566478403321 |
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Ragino Yuliya I
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dietary Intake and Type 2 Diabetes
| Dietary Intake and Type 2 Diabetes |
| Autore | Ojo Omorogieva |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (322 p.) |
| Soggetto non controllato |
low-carbohydrate
lipids carbohydrate restricted diet aldosterone high fat diet interleukin-6 rosemary extract Hedychium coronarium isomaltulose low carbohydrate diet folk medicine free fatty acids (FFA) high-density lipoprotein cholesterol mushroom protein and fat counting incretins fish oil almond Japanese vitamin D deficiency low energy diet AMPK women glycaemic index T2DM zinc status ginseng longitudinal analysis dietary management approaches glucose monitoring gut microbiome nutritional supplement carbohydrate counting gestational diabetes type 2 diabetes mellitus very-low-calorie inflammatory parameters vitamin D subjective appetite randomised controlled trial total body lean insulin secretion systematic review lactic acid bacteria food type 2 diabetes fish zinc intake glycaemic control diabetes dairy products glycated haemoglobin short chain fatty acids glycated hemoglobin A glycemic control vegetable oil standard formula cardiovascular risk factors DASH insulin dosage appendicular fat body composition total body fat micronutrients 25-OH-D obesity diabetes reversal enteral nutrition PUFA body mass index metabolic syndrome lifestyle management nutrition streptozotocin nuts enteral tube feeding lipid profile macronutrients triglyceride tempeh cohort study diabetes specific formula polyunsaturated fatty acids diabetes mellitus calcium intake hyperglycemia epidemiology trace elements dietary intake muscle appendicular lean peanut insulin resistance sucromalt pancreatectomy energy restricted diet glycemic index type 1 diabetes fasting blood glucose bariatric surgery prediabetes aronia meta-analysis chronic conditions diabetes management dietary pattern diet quality lipid parameters feces |
| ISBN | 3-03921-705-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367739603321 |
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Ojo Omorogieva
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Kidney Inflammation, Injury and Regeneration
| Kidney Inflammation, Injury and Regeneration |
| Autore | Koch Benjamin |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (496 p.) |
| Soggetto non controllato |
microRNAs
transcription ischemia/reperfusion injury DSS-colitis kidney inflammation therapeutics targets CXCL13 glomerulus interleukin-6 rhabdomyolysis IgA nephropathy CREB Regulated Transcriptional Coactivators (CRTC) slit diaphragm injury xanthine oxidase Salt Inducible Kinase (SIK) acute and chronic kidney disease therapeutic target KIT-IgA score G-protein-coupled bile acid receptor (TGR5) lysophosphatidic acid glomerular injury IL-18 mesenchymal stem cells Taiwan acute kidney injury renal ischemia-reperfusion long non-coding RNA fibrosis acute kidney failure diabetic kidney diseases chronic kidney disease lncRNA LPS-binding protein endotoxemia-induced oliguric kidney injury dapagliflozin cPLA2 and COX-2 NLRP3 inflammasome CmklR1 haem chronic kidney injury omega-3 fatty acid noninvasive inflammation regulated necrosis GLP-1 receptor agonists miRNA AKI SGLT2 inhibitors diabetic kidney disease extracellular vesicles podocin type IV collagen epithelial cells nephrin 2-kidney-1-clip renal fibrosis papilla diagnostics necrosis non-coding RNAs podocyte Thy1.1 nephritis KIT assay oxidative stress conditioned medium C-reactive protein pericyte myofibroblast Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-?B) endotoxemia modifier gene polymorphism renal stem cells kidney polyploidization Class IIa Histone Deacetylases (HDAC) 2k1c molecular signaling proximal tubule arachidonic acid empagliflozin tubular injury signaling cascade signal transduction inflammatory maker niches biomarkers renal progenitors type V collagen cyclooxygenase focal segmental glomerulosclerosis inflammatory bowel disease (IBD) chronic kidney disease (CKD) allograft rejection renovascular hypertension genotype molecular mechanisms ROS prediction glomerular filtration barrier (GFB) alport syndrome scattered tubular cells long non-coding RNAs renal inflammation lysophosphatidic acid receptor cAMP Regulatory Element Binding Protein (CREB) Farnesiferol B differentiation mesenchymal stromal cells modified-MSCs kidney transplantation polyunsaturated fatty acids apoptosis type I collagen diabetes mellitus natural products lipoxygenase stem cell T cell-mediated rejection exosomes renal injury obese kidney fibrosis kidney injury cytotoxicity mesenchymal stem cell pigment nephropathy mesodermal stem cell ischemia-reperfusion cytochrome P450 renal cell carcinoma hematuria B-cell attracting chemokine microRNA chemerin glomerular basement membrane glomerular damage renal tubular cells kidney proximal tubule exosome hypertension diabetic nephropathy |
| ISBN | 3-03928-539-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404091203321 |
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Koch Benjamin
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Membrane–Peptide Interactions : From Basics to Current Applications
| Membrane–Peptide Interactions : From Basics to Current Applications |
| Autore | Santos Nuno C |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (302 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
tachyplesin
host defense peptide anticancer antimicrobial antibiofilm peptide-membrane interaction structure-activity model membranes nuclear magnetic resonance solution structure accelerated molecular dynamics alamethicin membrane peptaibol cell-penetrating peptide peptide–lipid interaction lipid model systems molecular dynamics NMR membrane biophysics antimicrobial peptides non-lytic peptides bacterial membranes calcium hydroxide chemokine human beta defensin-3-C15 human dental pulp cell Streptococcus gordonii lipoprotein luffa sponge phosphopeptide mass spectrometry Matrix-assisted laser desorption ionization solid-phase extraction surface plasmon resonance melittin liposomes peptide–lipid interactions anti-microbial peptides pore-forming peptides ESKAPE pathogens Staphylococcus aureus KR12 LL-37 lipopeptide critical aggregation concentration CD spectroscopy biofilm cytotoxicity organisms sequence analysis machine learning feature selection sesame protein ACE inhibitory peptides simulated gastrointestinal digestion amino acid sequence molecular docking chionodracines circular dichroism membrane affinity cell-penetrating peptides circular dichroism spectroscopy atomic force microscopy mycolic acid Langmuir monolayer drug–peptide conjugates metastasis model of B16F10 melanoma Pisum sativum defensin 1 (Psd1) anti-metastatic activity glucosylceramide (GlcCer) cyclin F anti-inflammatory peptide cell permeable peptide heparin-binding peptide collagen-induced arthritis inducible nitric oxide interferon gamma interleukin-6 Enbrel |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
MembraneâPeptide Interactions
Membrane–Peptide Interactions |
| Record Nr. | UNINA-9910557551603321 |
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Santos Nuno C
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural Products and Disease Prevention, Relief and Treatment
| Natural Products and Disease Prevention, Relief and Treatment |
| Autore | Islam Md Soriful |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
Rubi Fructus
Rubus coreanus lipopolysaccharide macrophage ER stress calcium chop STAT cytokine nitric oxide β-glucan anticancer activity antioxidant anti-inflammatory cyclooxygenase lipoxygenase cauliflower mushroom breast cancer Spirulina tocotrienol immunomodulatory synergistic metastasis YG-1 extract bronchodilation fine particulate matter (PM2.5) acute lung injury airway inflammation pancreatic cancer natural product traditional medicine apoptosis angiogenesis drug resistance inflammation interleukin-6 sepsis Dracocephalum moldavica NASH lactoferrin fibrosis hepatocarcinogenesis connexin brown algae Sargassum plagiophyllum constipation gastrointestinal transit gut microbiota transepithelial transport glaucoma herbs retinal ganglion cells intraocular pressure SLC22A12 quercetin fisetin uricosuric activity anti-hyperuricemia functional food transporter uric acid health promotion rooibos tea doxorubicin mokko lactone heart Mokko lactone Dracocephalum moldavica ethanol extract Sparassis crispa fisetin and quercetin Sargassum plagiophyllum extract |
| ISBN | 3-0365-6138-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639988903321 |
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Islam Md Soriful
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutrition and Fitness : Mental Health
| Nutrition and Fitness : Mental Health |
| Autore | Dalle Grave Riccardo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (138 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
depressive symptoms
food insecurity nutrition adults generalized estimating equation review eating disorders physical activity problematic use of physical activity multiple sclerosis epigallocatechin gallate coconut oil interleukin-6 anxiety disability mental health emotional exhaustion cynicism professional efficacy sedentary behavior dietary behavior macronutrients energy intake motivation to diet motivation to exercise weight loss program obesity physical performance network analysis vitality psychiatry schizophrenia depression microbiota transplantation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Nutrition and Fitness |
| Record Nr. | UNINA-9910557477003321 |
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Dalle Grave Riccardo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting STAT3 and STAT5 in Cancer
| Targeting STAT3 and STAT5 in Cancer |
| Autore | Moriggl Richard |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (578 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
multiple myeloma
STAT3 S3I-1757 nanoparticle CD38 siRNA/RNAi polyethylenimine PEI lipopolyplex siRNA delivery glioma glioblastoma STAT5 AKT ERK1/2 prolactin androgens prostate cancer knockout escape mechanisms stem/progenitor cells cell hierarchy cancer CD4+ T cells CD8+ T cells myeloid cells immune check point hepatitis C virus (HCV) cirrhosis hepatocellular carcinoma (HCC) endoplasmic reticulum (ER) stress oxidative stress (OS) unfolded protein response (UPR) microRNA-122 (miR-122) nuclear factor erythroid 2-related factor 2 (NRF2) signal transducer and activator of transcription 3 (STAT3) hepatocyte nuclear factor 4 alpha (HNF4A) solid cancers cell cycle apoptosis inflammation mitochondria stemness tumor suppression melanoma autoimmune disease immunotherapy tumor-immune cell interactions breast cancer PD-L1 M2 macrophages NK cells STAT3 inhibitor XIII hedging transaction costs dynamic programming risk management post-decision state variable cancer progression cancer-stem cell cytokine therapy resistance metastasis immunosuppression tumor microenvironment proliferation tyrosine kinase 2 JAK family of protein tyrosine kinases signal transducer and activator of transcription cytokine receptor signaling gain-of-function mutation tumorigenesis ADAM17 interleukin-6 trans-signaling epidermal growth factor receptor (EGF-R) shedding metalloprotease tumor necrosis factor alpha (TNFα) inflammation associated cancer colon cancer lung cancer SH2 domain mutations autosomal-dominant hyper IgE syndrome inflammatory hepatocellular adenomas T-cell large granular lymphocytic leukemia T-cell prolymphocytic leukemia growth hormone insensitivity syndrome nuclear pore complex nuclear transport receptors nucleocytoplasmic shuttling targeting tumor-associated macrophages adoptive T cell therapy immune suppression STAT transcription factors JAK STAT T-PLL T-cell leukemia meta-analysis STAT5B signaling small-molecule inhibitors cancer models companion animals comparative oncology pharmacological inhibitor STAT5 signaling chemotherapy resistance myeloid leukemia heat shock proteins chaperones stabilization targeted therapy ovarian cancer hematopoietic cancers therapeutic targeting pharmacological inhibitors mTOR Bone Marrow Failure Syndromes lymphocytes lymphoma T-cells RHOA NGS MPN JAK2 V617F neoplastic stem cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557623503321 |
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Moriggl Richard
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Updates in Management of SARS-CoV-2 Infection
| Updates in Management of SARS-CoV-2 Infection |
| Autore | Flisiak Robert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (198 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
COVID-19
SARS-CoV-2 interleukin-6 tocilizumab therapy coronavirus disease 2019 cytokines severity prognosis mortality kidney failure rapid diagnostic test antigen detection Cytomegalovirus co-infections critical care liver markers inflammation morbidity personalized medicine liver functional tests COVID-19 pneumonia meta-analysis trial sequential analysis children clinical presentation coronavirus disease 2019 (COVID-19) epidemiology severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) clinical outcome symptomatology pandemic angiotensin 1 receptor (AT1R) AT1R concentration angiotensin II symptoms' severity diagnosis artificial intelligence medical imaging systematic umbrella review methodological credibility PCR test COVID-19 diagnosis Charlson Comorbidities Index cluster analysis longitudinal cluster individualized management |
| ISBN | 3-0365-5390-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619470303321 |
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Flisiak Robert
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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