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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (528 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
ABT-737
acetazolamide acetylcholine adjuvant therapy amoeboid motility angiogenesis apoptosis arthralgia Bcl-2 family BCL2L10 biomarkers BRAF BRAF inhibitor BRAF inhibitors BRAF-mutant melanoma cancer cancer associated fibroblast cancer stem cells carbonic anhydrase cell therapy checkpoint inhibitor cholinergic system combined therapy ctDNA CXCL10 cyclopamine cytokines cytotoxicity diagnosis DOCK4 drug resistance essential oils exosomes extracellular vesicles FAK hedgehog HIPPO HuR immunity immunotherapy interferon invasion ipilimumab lactate dehydrogenase lipid metabolism liquid biopsy liver-directed-therapies machine learning MANS peptide MARCKS mechanism of action melanoma melanoma immune infiltrate melanoma markers melanoma metastasis melanoma PDX melanomagenesis metalloproteinases metastases metastasis metastatic dormancy metastatic therapy metastatic uveal melanoma (mUM) microenvironment microRNAs MITF ML258 motility mucosal melanoma muscarinic receptors n/a nanoparticles nicotinic receptors nivolumab OXPHOS patient stratification PD-1 pembrolizumab phosphorylation plasmacytoid dendritic cells prediction principal component analysis prognosis prognostication protein tyrosine phosphatase PTPs inhibitors Rac1 radiotherapy resistance rheumatoid arthritis sex-hormones sex/gender ShcD adaptor protein siRNA slow cycling phenotype small molecules SOCE STAT3 Support Vector Machine survival target therapy targeted therapy targeted-therapy therapeutic resistance therapy TLR TPC2 tumor microenvironment tumour microenvironment uveal melanoma (UM) WNT5A |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Immunology
| Cancer Immunology |
| Autore | Subramanian Subree |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (316 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adaptive immunity
anti-CD20 antibody anti-CTLA-4 anti-PD-1 antibody-dependent cellular cytotoxicity (ADCC) antigen presenting cells antigen-presenting cells Atypical Chemokine Receptor 4 (ACKR4) B cell aplasia BAP1 BiFab bispecific antibody cancer cancer stem cells (CSCs) cancer vaccine CAR T carcinoma CD19-CAR-T CD28 cell therapy chemo-enzymatic approach chemotherapy classical and endemic Kaposi Sarcoma colon cancer colorectal cancer combination immunotherapy CTLA-4 cytotoxicity dendritic cells differentiation DNA methylation epidemiologic studies Fab IDO inhibitor IFN-γ IL-7 IL15 immune checkpoint blockade immune checkpoint inhibitors immune checkpoints immune evasion immunomodulation immunosuppression immunotherapy indoleamine 2,3 dioxygenase 1 inhibitory CAR innate immunity interferon KIR kynurenine pathway m6A melanoma MICA/B mAb multi-state modelling n/a NK cells NKG2D organ transplantation osteoclasts PD-1 PD-L1 primary liver cancer prostate cancer resistance RNA methylation S-adenosylmethionine (SAM) sortase A systemic treatment T cells T-cell priming TCR diversity TIL treatment free interval Treg cells triple negative breast cancer tryptophan 2,3 dioxygenase 2 tumor microenvironment tumor-infiltrating lymphocytes uveal |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557349203321 |
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Subramanian Subree
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cell Biology of Viral Infections
| Cell Biology of Viral Infections |
| Autore | Lozach Pierre-Yves |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (418 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
3D cultures
3D imaging actin cytoskeleton adenovirus alphaviruses alternative splicing angiogenesis inhibitor antigen presentation antiviral antiviral autophagy antiviral peptide apoptosis Arp2/3 complex astrocyte infection autoimmunity autophagy bacterial invasion biological activity BoHV-1 UL49.5 CAD calcium channels calcium pumps cancer immunotherapy cedar virus cell death cell-cell transmission cell-free infection coronavirus Ebola virus ectoderm embryogenesis embryoid body endocytosis endoplasmic reticulum envelope disruption enveloped viruses environmental restriction epigenetic signature ERAP2 ERAP2/Iso3 erlin-1 erlin-2 ESCRT machinery factory FECV feline coronavirus feline enteric coronavirus feline infectious peritonitis virus feline intestinal organoids filovirus FIPV fluorescent TAP platform fusion protein galectin Golgi hantavirus HCV henipavirus hepatitis C virus herpes simplex virus HEV HIV-1 spread host cell response host factor human development immune checkpoint inhibitor immune evasion inclusion bodies inflammation interferon interferon regulatory factor interferon response interferon-induced genes lipid droplet liquid organelles lysophagy mathematical modeling membrane damage membrane phosphatidylserine MERS-CoV mesoderm metabolism MHC I microbial infections mosquito mRNA export nucleocapsid transport NXF1 oncolytic virus particle production protein production pyrimidine synthesis rabies rabies pathogenicity replication RNA replication RNA synthesis SARS-CoV SARS-CoV-2 self-organizing map (SOM) data portrayal sialic acid Siglec STAT stress granules TAP-GFP TGF-β and Wnt/β-catenin pathway tolerance Tula virus tumor necrosis factor uDISCO viral replication virus virus entry virus production virus-host interaction |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557135903321 |
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Lozach Pierre-Yves
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chronic HCV Infection: Clinical Advances and Eradication Perspectives
| Chronic HCV Infection: Clinical Advances and Eradication Perspectives |
| Autore | Liberto Maria Carla |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (104 p.) |
| Soggetto topico |
Epidemiology and Medical statistics
Medicine and Nursing |
| Soggetto non controllato |
children
chronic hepatitis C COVID-19 direct-acting antivirals elimination fibrosis genotype 3 HCV HCV eradication hepatitis C hepatitis C virus (HCV) hepatocellular carcinoma homeless persons interferon ledipasvir/sofosbuvir liver cirrhosis model mortality n/a out-of-hospital pangenotypic phylogeny PWID real-life resistance-associated substitution (RAS) retention in care rheumatic steatosis sustained virological response vibration controlled transient elastography |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Chronic HCV Infection |
| Record Nr. | UNINA-9910557608603321 |
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Liberto Maria Carla
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytokine-mediated Organ Dysfunction and Tissue Damage Induced by Viruses
| Cytokine-mediated Organ Dysfunction and Tissue Damage Induced by Viruses |
| Autore | Lehmann Michael H |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (170 p.) |
| Soggetto topico |
Immunology
Medicine and Nursing |
| Soggetto non controllato |
chemokine
CVB3 Hantavirus hcmv HIV Inflammation influenza interferon |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557223403321 |
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Lehmann Michael H
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Family Iridoviridae Molecular and Ecological Studies of a Family Infecting Invertebrates and Ectothermic Vertebrates / Amanda Duffus, Gregory Chinchar
| Family Iridoviridae Molecular and Ecological Studies of a Family Infecting Invertebrates and Ectothermic Vertebrates / Amanda Duffus, Gregory Chinchar |
| Autore | Duffus Amanda |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
risk assessment
CQIV mathematical models amphibian iridovirus ISDL Exopalaemon carinicauda viral load virus isolation European chub outbreak Unconventional T cell early detection susceptible species viral immune evasion DNA virus Rana grylio virus antibody intracellular localization Rana grylio virus (RGV) British Columbia Iridoviridae Andrias davidianus ranavirus viral infection susceptible-infected (SI) models yeast two-hybrid (Y2H) prevalence host-pathogen interactions Pacific herring Procambarus clarkii Bayesian inference eDNA amphibians Artemia spp ranavirosis cross-species transmission FV3 SHIV Gryllus bimaculatus Pacific salmon NF-?B cricket IIV-6 virus binding erythrocytic necrosis virus (ENV) envelope protein iridovirus core proteins emerging infection host Ranavirus white head Rana temporaria Imd biosecurity antiviral immunity Decapodiridovirus endemic disease Macrobrachium rosenbergii co-immunoprecipitation (Co-IP) Common frog aquatic animals virus surveillance immunomodulators frog virus 3 ELISA DIV1 megalocytivirus Lymphocystis disease virus bearded dragon susceptibility protein interaction Pogona vitticeps viral erythrocytic necrosis (VEN) histopathology epidemiology native-fish conservation viral transmission Sparus aurata immunohistochemistry lizard disease dynamics immunofluorescence transmission modelling Macrobrachium nipponense interferon nonclassical MHC heparan sulfate ranavirus Mexico |
| ISBN |
9783039215171
3039215175 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367754803321 |
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Duffus Amanda
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Glycomics
| Marine Glycomics |
| Autore | Fujii Yuki |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (208 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
accumulation of carbohydrates
Acropora tenuis Alexandrium catenella antibacterial activity anticancer activity anticoagulant anticoagulant activity antifungal activity antiparasitic activity antiviral response Aplysia kurodai apoptosis Arthrospira platensis bacterial exopolysaccharides bioactive properties bioflocculanting activity biohydrogen bivalve mollusk C-type lectins C1q domain-containing C1q domain-containing proteins chemoattraction Chlorella vulgaris contact activation coral cryptosporidiosis Dunaliella salina Ehrlich ascites carcinoma fucoidan fucosylated chondroitin sulfate fucosylated glycosaminoglycan galectins growth rate harmful algal bloom-forming dinoflagellate hypotension innate immunity interferon interstitial compartment lectin lectin-like leishmaniasis malaria Mameliella alba marine hydrobionts marine worms microalgae growth-promoting bacterium microbe-associated molecular patterns n/a oncolytic vaccinia virus oral administration pattern recognition receptor pattern recognition receptors peptides platelet aggregation polysaccharides protozoa pulmonary embolism rotifera schistosomiasis sipunculids sulfated fucan sulfated fucose-rich polysaccharides sulfated polysaccharides trichomoniasis trypanosomiasis white-spotted charr lectin |
| ISBN | 3-0365-5822-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637782803321 |
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Fujii Yuki
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Matrix Metalloproteinase
| Matrix Metalloproteinase |
| Autore | Ågren Magnus S |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (262 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
a disintegrin and metalloproteinase
ADAM ADAMTS adult aggrecan aggrecanase Agkistrodon venom allodynia anticoagulants antithrombotic apoptosis arthritis blood sampling cancer cartilage caspase-3 CD147 central nervous system chemokine cytokine cytokines diseases dorsal root ganglion ectodomain shedding EMMPRIN extracellular matrix extracellular matrix breakdown fibrinogen gastric cancer glycosaminoglycans glycosylation hemagglutinin-B high-molecular-weight heparin HIV-TB-associated IRIS IL-11 IL-16 IL-6 IL-8 inflammation inhibitor interferon interleukin interstitial collagens invasion lung matrix metalloproteinase matrix metalloproteinases matrix metalloproteinases (MMPs) matrix-metalloproteinase meprin metabolomics metalloproteases metalloproteinase metastatic dissemination MMP MMP-2 MMP-9 MMPs monocytes MT4-MMP neuropathic pain pediatric peritoneal mesothelial cell phagocytosis phosphorylation protease proteinases proteomics PTMs sICAM-1 signaling spinal nerve ligation T cells TNF-α trans-signaling transwell co-cultures tuberculosis tuberculous meningitis wound healing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557717203321 |
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Ågren Magnus S
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ubiquitination in Health and Diseases
| Ubiquitination in Health and Diseases |
| Autore | Ishigami Tomoaki |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (292 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
aggregation
aldosterone sensitive distal nephron blood pressure cancer cilia ciliogenesis ciliopathy cortical bone derived stem cell degradation deubiquitinase deubiquitinases deubiquitination differentiation disulfide-coupling dopa-responsive dystonia DUBs E3 ubiquitin ligase E3s endoplasmic reticulum stress epithelial sodium channel excitation-transcription coupling fatty acid-binding protein 3 fibrils genetic diseases hematopoiesis hematopoietic stem cells immune response immune-related diseases inflammation inhibitor inhibitors innate immune interferon LUBAC mesenchymal stem cell mitochondria MITOL/MARCH5 monoubiquitin signaling mTOR myocardial infarction Nedd4L/Nedd4-2 neurodegeneration neurodegenerative disease NF-κB osmotic stress Parkinson's disease polyubiquitin proliferation proteasomal degradation protein complex formation protein quality control protein stabilization proteolysis regulation of gene expression regulatory T cells renal salt reabsorption RING finger RNF152 RNF182 RNF183 RNF186 salt-sensitive hypertension semisynthesis tau protein therapeutic target tyrosine hydroxylase ubiquitin ubiquitin code ubiquitin ligase ubiquitin proteasome system ubiquitin system ubiquitin-proteasome pathway ubiquitin-proteasome system ubiquitination UPS vascular function vesicular trafficking virus infection virus-host interaction α-synuclein |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557356403321 |
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Ishigami Tomoaki
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Zika Virus and Host Interactions
| Zika Virus and Host Interactions |
| Autore | Hobman Tom |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (256 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
anti-viral signaling
apoptosis arboviruses astrocytes Bcl-2 protein family blood-placental barrier C6/36 cells cell death cell entry cellular communication claudins cytokine endothelial vascular cells envelope protein extracellular vesicles fetal brain flavivirus flaviviruses fusion loop glycosylation guinea pig host host-pathogen interactions HSP90 human monocytes IFN IFNAR1 immune response infertility inflammation inflammatory mediator innate immune response innate immunity interferon JAK/STAT Leydig cells MDA5 mosquito MR766 network non-structural viral proteins NS5 NS5 protein nuclear localization pathogenesis peroxisome peroxisomes placenta protein-protein interaction RIG-I Sertoli cells sexual transmission subcutaneous T cells tight junction tight junctions vaginal viral fusion viral replication virus host interactions virus transmission virus-host interactions West Nile virus zika zika virus Zika virus ZIKA virus ZIKV ZO-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557297503321 |
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Hobman Tom
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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