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Antivirals for Emerging Viruses: Vaccines and Therapeutics
| Antivirals for Emerging Viruses: Vaccines and Therapeutics |
| Autore | Rong Lijun |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (373 p.) |
| Soggetto topico |
Science: general issues
Medical microbiology & virology Microbiology (non-medical) |
| Soggetto non controllato |
Emerging viruses
antivirals inhibitors vaccines small molecules peptides antibody |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antivirals for Emerging Viruses |
| Record Nr. | UNINA-9910557227103321 |
Rong Lijun
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomimetic Radical Chemistry and Applications 2021
| Biomimetic Radical Chemistry and Applications 2021 |
| Autore | Chatgilialoglu Chryssostomos |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (244 p.) |
| Soggetto topico |
Research & information: general
Chemistry Inorganic chemistry |
| Soggetto non controllato |
guanine
guanyl radical tautomerism guanine radical cation oligonucleotides DNA G-quadruplex time-resolved spectroscopies reactive oxygen species (ROS) oxidation catalase mimics peroxide diiron-peroxo complexes structure/activity kinetic studies biomimetic chemistry cysteine ketone reduction free radicals pulse radiolysis kinetics DNA oxidation DNA hole transfer molecular dynamics quantum dynamics electron transfer charge transfer quantum coherence chemiluminescence reaction mechanisms singlet oxygen reactive oxygen species light emission crosslink dimerization protein oxidation radicals di-tyrosine di-tryptophan disulfides thiols aggregation proteomics mass spectrometry collagen riboflavin hyaluronic acid EPR spectroscopy keratoconus STEM DNA biosensor chemical nucleases DNA-drug interaction copper complexes metallodrugs MEP pathway antibiotics IspH LytB [4Fe-4S] cluster reductive dehydroxylation bioorganometallic intermediate inhibitors methionine neighboring group effect hydroxyl radical triplet state of carboxybenzophenone one-electron oxidants laser flash photolysis peptides proteins |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576882903321 |
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Chatgilialoglu Chryssostomos
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cell Biology of Galectins
| Cell Biology of Galectins |
| Autore | Timoshenko Alexander |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
galectin-7
p53 MMP-9 cancer gain-of-function vasculature gene expression tube formation sprouting VEGF integrins galectin extracellular matrix microenvironment Yersinia enterocolitica YopP Galectin-1 nitric oxide macrophages epithelial tissues apoptosis targeting inhibitors β-hairpin β-sandwich blood group B lectin sugar code LGALS16 placenta brain tissues cell differentiation transcription factor miRNA galectin-3 cardiac fibrosis heart failure atrial fibrillation chronic inflammation MMPs microRNAs lncRNAs pectin structure and function bioactive polysaccharides galectin-3 inhibition galacto-oligosaccharides galectins intestinal epithelial cells β-3'galactosyllactose immunomodulation mucosal immunity O-GlcNAc unconventional secretion extraembryonic endoderm |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580216003321 |
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Timoshenko Alexander
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Combating Antimicrobial Resistance - A One Health Approach
| Combating Antimicrobial Resistance - A One Health Approach |
| Autore | Matar Ghassan M |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (326 p.) |
| Soggetto topico |
Science: general issues
Infectious & contagious diseases |
| Soggetto non controllato |
resistance mechanisms
combination therapy Novel antibiotics Natural Products mode of action Therapeutics antimicrobials inhibitors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557465503321 |
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Matar Ghassan M
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics
| Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics |
| Autore | Tutone Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (387 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
3D-QSAR
pharmacophore modeling ligand-based model HDACs isoform-selective histone deacetylase inhibitors aminophenylbenzamide hERG toxicity drug discovery fingerprints machine learning deep learning gene expression signature drug repositioning approaches RNA expression regulation high-throughput virtual screening dual-target lead discovery neurodegenerative disorders Alzheimer's disease dual mode of action multi-modal nicotinic acetylcholine receptor acetylcholinesterase molecular docking methotrexate drug resistance human dihydrofolate reductase virtual screening molecular dynamics simulation epitope binning epitope mapping epitope prediction antibody:antigen interactions protein docking glycoprotein D (gD) herpes simplex virus fusion proteins Src inhibitors pharmacophore model molecular dynamics simulations in silico COX-2 inhibitors molecular modeling sodium-glucose co-transporters 2 FimH uropathogenic bacteria urinary tract infections diabetes drug-resistance mutations HIV-2 protease structural characterization induced structural deformations SARS-CoV-2 COVID-19 multiprotein inhibiting natural compounds MD simulation 3CL-Pro antivirals docking simulations drug repurposing consensus models binding space isomeric space MRP4 SNPs variants protein threading modeling molecular dynamics binding site hTSPO PK11195 cholesterol homology modeling molecular dynamics (MD) simulation carbon nanotubes Stone-Wales defects haeckelite defects doxorubicin encapsulation drug delivery system binding free energies noncovalent interactions main protease mutants inhibitors PF-00835231 Mycobacterium tuberculosis tuberculosis proteasome natural compounds multiscale multitargeting polypharmacology computational biology drug repositioning structural bioinformatics proteomic signature skin aging oxidative stress aging progression mechanism genome-wide genetic and epigenetic network (GWGEN) systems medicine design multiple-molecule drug immunoproteasome non-covalent inhibitors MD binding metadynamics induced-fit docking |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Computational Approaches |
| Record Nr. | UNINA-9910557519403321 |
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Tutone Marco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational Methods for Polymers
| Computational Methods for Polymers |
| Autore | Soroush Masoud |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (320 p.) |
| Soggetto topico | History of engineering & technology |
| Soggetto non controllato |
rapid tooling
additive manufacturing failure modes injection molding modeling olefin gas phase kinetics hyperbranched Monte Carlo simulation radius of gyration span length continuous stirred-tank reactor data-driven parameter estimation retrospective cost model refinement algorithm global sensitivity analysis polyolefin synthesis olefin copolymerization reactivity ratios electronic effects salan catalysts post-metallocene DFT insertion kinetics olefin capture PolyEThyleneAmidoAmine (PETAA) dendrimer molecular topological indices Eccentric connectivity index copolymerization design of experiments reactivity ratio estimation terpolymerization PLP-SEC n-butyl acrylate degree of branching nanostar dendrimer irregularity measure complexity of structure NS1[p] NS2[p] NS3[p] subspace identification polymer processing model predictive control rotational molding batch process modeling and control method of moments free-radical polymerization methyl acrylate thermal polymerization high-temperature polymerization molecular graph irregularity indices dendrimers density functional theory inhibitors phenolic stable nitroxide radicals styrene polymerization RAFT polymerization multi-rate observer nonlinear sampled-data system measurements with delay parameter fitting droplet impact viscoelasticity volume of fluid method process intensification operability modularity process modeling and simulation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557486203321 |
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Soroush Masoud
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor
| Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor |
| Autore | Holzmann Klaus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (276 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
FGFR4
FGF19 gene regulation cancer signaling anticancer FRS2 FGFR NVP-BGJ398 LY2874455 sarcoma cancer-associated fibroblasts GPER breast cancer estrogen FGFR1 FGF2 optogenetics ERK AKT receptor kinase neurite outgrowth HEK293 PC12 fibroblast growth factor receptors signaling receptor cross-talk coreceptor membrane proteins FGFR2 ERK1/2 phosphorylation serine negative feedback loop cancer prognosis HCC inhibitors FGF fibroblast growth factor autocrine signaling skin melanoma squamous and basal cell carcinoma seborrheic keratosis targeted therapy resistance structure kinase inhibitor gastric cancer monoclonal antibody small molecule FGFR2c autophagy keratinocyte MTOR JNK1 review malignant glioma brain cancer astrocytoma Sprouty proteins FGF-mediated signaling tumor suppressor tumor promoter malignant pleural mesothelioma overall survival immunohistochemistry infigratinib sensitivity FGF8 FGF18 adenocarcinoma of the esophagogastric junction neoadjuvant therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Fibroblast Growth Factor Receptor |
| Record Nr. | UNINA-9910557898903321 |
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Holzmann Klaus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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mTOR Signaling in Metabolism and Cancer
| mTOR Signaling in Metabolism and Cancer |
| Autore | Huang Shile |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
mTOR
histone deacetylase prostate cancer integrins adhesion invasion cell metabolism T cells Foxp3 Acute Lymphoblastic leukemia targeted therapy metabolism cell signalling mTOR signalling head and neck cancer mutant genes biomarkers targeted therapies clinical trials cancers inhibitors photodynamic therapy PI3K Akt skin cancers phytochemicals melanoma basal cell carcinoma squamous cell carcinoma Merkel cell carcinoma TNBC eribulin PI3K/AKT/mTOR everolimus combination synergy mTOR signaling tissue regeneration neuron muscle liver intestine hematologic malignancies regulatory T cells tumor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557107203321 |
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Huang Shile
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Probing the Ubiquitin Landscape
| Probing the Ubiquitin Landscape |
| Autore | Ovaa Huib |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (205 p.) |
| Soggetto topico | Science: general issues |
| Soggetto non controllato |
ubiquitin(-like)
activity-based probes toolbox development applications inhibitors proteomics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557216803321 |
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Ovaa Huib
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Quorum Network (Sensing/Quenching) in Multidrug-Resistant Pathogens
| Quorum Network (Sensing/Quenching) in Multidrug-Resistant Pathogens |
| Autore | Garcia-Conteras Rodolfo |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (237 p.) |
| Soggetto topico |
Science: general issues
Infectious & contagious diseases |
| Soggetto non controllato |
Quorum
Sensing quenching Enzymes Molecules inhibitors activators regulation animal-models techniques |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Quorum Network |
| Record Nr. | UNINA-9910557497003321 |
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Garcia-Conteras Rodolfo
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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