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Advances in DNA Vaccines
| Advances in DNA Vaccines |
| Autore | Isaguliants Maria |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (210 p.) |
| Soggetto topico |
Medicine
Epidemiology & medical statistics |
| Soggetto non controllato |
alphaviruses
layered RNA/DNA vectors DNA vaccines RNA replicons recombinant particles tumor regression protection against tumor challenges and infectious agents ebola virus disease artificial T-cell antigens DNA vaccine constructs computer design gene expression immunogenicity DNA vaccine mRNA vaccine plasmid DNA in vitro transcribed mRNA immune responses formulations Cytolytic T Lymphocytes antibodies innate immunity adjuvants vaccine delivery plasmid cytolytic perforin bicistronic HCV HIV IL-36 adjuvant DNA Zika Epstein-Barr virus latent proteins LMP2 EBNA1 LMP1 HIV-1 enhancer element circovirus influenza immunization intranasal lipid flagellin BCG vaccine rBCG HTI T-cell AIDS clinical trial therapeutic vaccine hepatitis C virus (HCV) mesenchymal stem cells (MSC) modified MSC DNA immunization nonstructural HCV proteins immune response HCV vaccine myeloid derived suppressor cells (MDSCs) |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557354503321 |
Isaguliants Maria
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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COVID-19: Current Challenges and Future Perspectives
| COVID-19: Current Challenges and Future Perspectives |
| Autore | Leggat Peter |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (264 p.) |
| Soggetto topico |
Medicine
Environmental medicine |
| Soggetto non controllato |
COVID-19
SARS-CoV-2 hepatitis B and C cirrhosis chronic kidney disease alcohol-related liver disease nonalcoholic steatohepatitis necrosis MDR-TB clinical trials IL-6 inhibitors tocilizumab cytokine release syndrome cytokine storm operational research health systems SORT IT pandemics training pandemic endemic tuberculosis impact control overview malaria preparedness Africa emergency fecal calprotectin bowel perforation D-Dimer thrombosis ischemia efficacy safety kaletra lopinavir/ritonavir meta-analysis coronavirus SARS-CoV-1 MERS SARS influenza healthcare worker healthcare personnel general practitioners medical doctor heart transplant CMV Chagas disease infection severity respiratory viruses coinfections health care workers Philippines rhinovirus severe acute respiratory syndrome coronavirus 2 plasmodium falciparum differential diagnosis cognitive bias diagnostic reasoning recurrence reinfection Bangladesh Kenya Nairobi presumptive tuberculosis TB treatment outcomes HIV antiretroviral therapy EpiCollect5 Malawi Lilongwe Zimbabwe Harare real-time operational research ethics research capacity building India Nepal post-acute COVID-19 syndrome COVID-19 vaccines mortality epidemiology public health healthcare workers attitudes perceptions knowledge |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | COVID-19 |
| Record Nr. | UNINA-9910566469103321 |
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Leggat Peter
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytokine-mediated Organ Dysfunction and Tissue Damage Induced by Viruses
| Cytokine-mediated Organ Dysfunction and Tissue Damage Induced by Viruses |
| Autore | Lehmann Michael H |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (170 p.) |
| Soggetto topico |
Medicine
Immunology |
| Soggetto non controllato |
chemokine
CVB3 Hantavirus hcmv HIV Inflammation influenza interferon |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557223403321 |
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Lehmann Michael H
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function
| Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function |
| Autore | Pulido Rafael |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (240 p.) |
| Soggetto non controllato |
hematopoietic cells
DEPArray neuroblastoma liver steatosis MAPK phosphatase DUSP-4 granule neurons neuronal differentiation DUSP10 cytokines MAPKs single cell analysis macrophage asthma E. coli infection MAPK Cpp1 nucleotide receptors atypical DUSP RSV Pmp1 cannabinoids astrocytes sepsis influenza signaling triple-negative breast cancer (TNBC) differentiation HDAC6 (histone deacetylase isoform 6) atypical dual-specificity phosphatases microtubules respiratory viruses MK-STYX (MAPK (mitogen-activated protein kinase) phosphoserine/threonine/tyrosine-binding protein) dual-specificity phosphatase Msg5 TLR signaling mitogen-activated protein kinase fungal MKPs macrophages MAP Kinase Phosphatase-2 inflammation Sdp1 circulating tumor cells (CTCs) MAP kinases MAP kinase phosphatases P2X7 proliferation BDNF P2Y13 T cell hypertriglyceridemia integrated omics analysis post-translational modification rhinovirus protein stability ubiquitination dual-specificity phosphatases Mkp-1 cancer brain metastasis HER2 COPD pseudophosphatase |
| ISBN | 3-03921-689-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Dual Specificity Phosphatases |
| Record Nr. | UNINA-9910367740903321 |
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Pulido Rafael
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Impaired Mitochondrial Bioenergetics under Pathological Conditions
| Impaired Mitochondrial Bioenergetics under Pathological Conditions |
| Autore | Lenaz Giorgio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (460 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
aging heart
Bcl-2 family mitochondria programmed cell death fatty acid oxidation palmitate oleate m.3243A> G mutation MT-ATP6 m.8909T> C ATP synthase nephropathy oxidative phosphorylation mitochondrial disease cardiolipin Barth syndrome Sengers syndrome respiratory chain Dilated Cardiomyopathy with Ataxia cardiomyopathy mammalian complex I NADH dehydrogenase complex I assembly complex I structure complex I deficiency supernumerary subunits electron transport chain mitochondrial dysfunction Leigh syndrome mitochondrial diseases yeast Saccharomyces cerevisiae pet mutants pancreatic endocrine cells mathematical model cellular bioenergetics diabetes glucagon insulin exercise immune system metabolic disease COVID-19 mitochondrial dynamics viral infections MAVS RIG-I MDA5 innate immune response SARS CoV-2 RSV influenza respiratory supercomplexes ROS ATP synthase/hydrolase mitochondrial permeability transition pore cristae cellular signaling human disease mitochondrial dynamic cell signaling cancer respiratory complexes oxidative stress mitochondrial DNA MTCYB mutations cytochrome b complex III aging energy metabolism entorhinal cortex lipoxidation-derived damage neurodegeneration oxidative damage protein import respiratory complex assembly supercomplexes mitochondrial proteostasis heart failure bioenergetics assembly factor atypical myopathy high-resolution respirometry toxicity assays cell culture equine primary myoblasts fibroblasts frozen tissue leukocytes oxygen consumption platelets respirometry skeletal muscle |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585934503321 |
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Lenaz Giorgio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Influenza Virus and Vaccination
| Influenza Virus and Vaccination |
| Autore | Nogales Aitor |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (130 p.) |
| Soggetto non controllato |
heterosubtypic immunity of influenza
master donor virus imprinting hemagglutinin universal vaccines pandemic adaptive immunity pregnant women innate immunity antibodies Influenza vaccine ARDS influenza A virus humoral response influenza vaccine original antigenic sin “OAS” germinal centers immunogenicity lung epitopes Influenza virus single nucleotide polymorphisms (SNPs) influenza virus protein microarray assay “universal” influenza vaccine vaccination influenza multiple dimensional assay (MDA) infection tissue resident memory vaccines CD4 T cell broad neutralizing antibody(bnAb) hemagglutinin (HA) of influenza virus original antigenic sin immune response morbidity T cell mPLEX-Flu assay Influenza A virus (IAV) virus–host interaction hemagglutin stalk memory B cells vaccine safety protection efficacy live attenuated influenza vaccine pediatrics vaccination rate |
| ISBN | 3-03928-818-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404076903321 |
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Nogales Aitor
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Biology of Selenium in Health and Disease
| Molecular Biology of Selenium in Health and Disease |
| Autore | Tsuji Petra A |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (384 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
selenoproteome
selenoprotein hierarchy nonradioactive isotopes SEC-ICP MS glutathione peroxidase thioredoxin reductase SECIS translation regulation autoimmune thyroid disease diabetes mellitus Graves' disease Hashimoto thyroiditis infection inflammation long-COVID rheumatoid arthritis selenoprotein P sepsis selenoprotein W thioredoxin 14-3-3 Akt cell death Selenof selenium selenoprotein colon cancer barrier integrity cardiovascular heart selenoproteins Keshan's Disease bacteria selenite selenium delivery system Trsp hypothalamus Agrp neuron sex differences diet-induced obesity leptin resistance macrophage differentiation redox signaling NRF2 NF-κB lipid mediators seleocysteine autoimmunity lymphocyte cadmium cytotoxicity cancer therapy cisplatin ICP-MS nonsynonymous mutation selenium homeostasis ZIP8 Trit1 isopentenylation tRNA[Ser]Sec selenocysteine genetic variance human disease selenophosphate synthetase endothelial cell reactive oxygen species cell growth angiogenesis SEPHS1 early embryogenesis embryonic lethality prostate cancer tumor suppressor selenoprotein deficiency SECISBP2 Sec-tRNA[Ser]Sec SEPSECS antioxidative defense autoantibody Hashimoto's thyroiditis trace element recoding SECIS-binding protein translation termination nonsense-mediated decay ribosome rescue health mouse models selenocysteine (Sec) virus viral antioxidant HIV HCV HBV coxsackie virus influenza HIV-1 viral infection SELENOS SELENOO primary T cells Jurkat SupT1 translational control |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566482103321 |
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Tsuji Petra A
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nanobody
| Nanobody |
| Autore | Rothbauer Ulrich |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Bacillus anthracis
immunoassay single-domain antibody genetic fusion Beta galactosidase P-type ATPase nanobody llama Zinc-transport Zinc-transporting P-ATPase ZntA TNF fluorescent nanobodies sensor anti-cytokine therapy autoimmune disease Western equine encephalitis virus MagPlex toxin antibody camelid vaccine biodefense hydrogen exchange-mass spectrometry virus formatting Fc-domain half-life ischemia stroke MCAO single domain antibodies phage display intrabody intracellular antibody GTPase RHO BRET RAS chromobodies live-cell imaging compound screening cellular models single-domain antibody fragments molecular imaging molecular therapy nuclear imaging targeted fluorescence imaging intraoperative imaging Nanobody Single Domain Antibody Cancer Immunotherapy Imaging influenza influenza B virus hemagglutinin single domain antibody NanobodyTM yeast display epitope mapping GFP C. elegans development drosophila zebrafish targeted photodynamic therapy hepatocyte growth factor receptor HGFR c-Met Met VHH photosensitizer single-domain antibodies neurodegenerative diseases brain imaging blood-brain barrier delivery Aids HIV Llama Antibodies bi-specific VHH pepscan competition studies co-crystallisation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557147503321 |
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Rothbauer Ulrich
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oligonucleotide, Therapy, and Applications
| Oligonucleotide, Therapy, and Applications |
| Autore | Aliño Salvador |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (123 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
quantum dots (QDs)
DNAzyme ROS Amplex Red light-induced activity DNA methylation histone code microRNA nanoparticles noncoding RNA pulmonary arterial hypertension aptamer aptasensor influenza SERS virus detection α-synuclein antisense oligonucleotide dopamine neurotransmission double mutant A30P*A53T* motor deficits Parkinson’s disease transgenic mouse model G-quadruplexes covalent dimer construct anti-proliferative activity primary cell culture of human glioma antisensense oligonucleotide Foxp3 regulatory T cells vaccine immunogenicity Sporothrix schenckii Marfan syndrome fibrillin-1 antisense oligonucleotides exon skipping splice-switching |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557615903321 |
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Aliño Salvador
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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One Health and Zoonoses
| One Health and Zoonoses |
| Autore | Mackenzie John |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (140 p.) |
| Soggetto non controllato |
descriptive epidemiology
antimicrobials real-time PCR guinea pigs pandemic vector-borne disease Ebola virus transmission antimicrobial resistance serology microbats smallholder farming WHO AMR Clostridium difficile zoonoses water zoonosis scrub typhus Q fever emerging disease antibiotics clinical pattern food chain influenza pyrogenicity Western Australia Brucella abortus Luminex epidemiology Joint External Evaluation (JEE) prevalence Performance of Veterinary Services (PVS) World Trade Organization (WTO) urban livestock keeping surveillance human C. burnetii Australian bat lyssavirus One Health wildlife emerging infectious diseases mosquito Codex international health regulations swine environment trade Asia infrastructure Japanese encephalitis virus Australia incidence |
| ISBN | 3-03921-296-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367567803321 |
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Mackenzie John
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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