Molecular Psychiatry
| Molecular Psychiatry |
| Autore | Rein Theo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (288 p.) |
| Soggetto topico |
Medicine and Nursing
Mental health services |
| Soggetto non controllato |
(2R,6R)-Hydroxynorketamine
5-HT 4 receptor 5-HT4R acid sphingomyelinase actin dynamics affective temperament alcohol dependence alpha-synuclein Alzheimer's disease antidepressant antidepressant treatment antidepressants antipsychotics basic-helix-loop-helix BDNF behavior biomarker discovery biomarkers bipolar disorder brain cardiovascular disease cell adhesion molecules chemokines childhood-onset schizophrenia (COS) circadian rhythms coactivator cognition copy number variation (CNV) cordance CRMP-2 CyP40 cytoskeleton dendritic arborization depression DISC1 DNA methylation dopaminergic gene polymorphisms DRR1 drug design early neurodevelopment electroconvulsive therapy endocrinology expression FAM107A FKBP5 FKBP51 FKBP52 forced swimming gender gene expression general cognitive function genetic correlation glucocorticoids GR GWAS Hamilton Scale of Depression hippocampus HPA axis Hsp90 Immune response immunohistochemistry immunology induced pluripotent stem cell (iPSC) inflammation intelligence Ketamine liver enzymes machine learning major depression major depressive disorder mineralocorticoid receptor knockout miRNAs molecular chaperones mood disorder multi-target drugs multi-task learning n/a nervous system neurodevelopment neuroinflammation neuronal differentiation obesity Parkinson's disease polypharmacology PP5 PPARγ proteomics PSA-NCAM psychiatric disease psychiatry rapid-acting resilience response variability Roman rat lines schizophrenia serotonin sex difference sleep sleep EEG SNCA social defeat sphingolipid metabolism steroid hormones stress stress physiology stress response susceptibility synapse T cells Th17 cells transcription biology Treg cells trkB TU3A western blot withdrawal |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557793503321 |
Rein Theo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Therapies for Inherited Retinal Diseases
| Molecular Therapies for Inherited Retinal Diseases |
| Autore | Collin Rob W.J |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (262 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
AAV
ABCA4 adeno-associated viral adeno-associated virus (AAV) allele-specific knockdown antisense oligonucleotides AON-mediated exon skipping apical polarity apoptosis ARPE-19 cells autophagy autosomal dominant bipolar cells CEP290 chaperones chaperonins choroideremia Cilia elongation clathrin-coated vesicles clinical trials clustered regularly interspaced short palindromic repeats (CRISPR) compound therapies cones crumbs complex cyclic GMP DNA therapies DNA-wrapped gold nanoparticles drug delivery systems dual AAV endosomal trafficking Enhanced S-Cone Syndrome (ESCS) fetal retina Flanders founder c.4723A > G56R gapmer antisense oligonucleotides gene augmentation gene therapy gold nanoparticles heat shock response homology-directed repair (HDR) induced pluripotent stem cell (iPSC) inherited retinal disease inherited retinal diseases iPSC-derived photoreceptor precursor cells IRD Leber congenital amaurosis Leber congenital amaurosis and allied retinal ciliopathies microRNA Müller glia n/a necrosis nonprofit NR2E3 PAR complex patient registry photoreceptors protein degradation protein folding protein trafficking putative dominant negative effect REP1 retina retinal degeneration retinal inherited disorders retinal organoids retinal pigment epithelium retinitis pigmentosa Retinitis Pigmentosa (RP) Retinitis Pigmentosa GTPase Regulator retinogenesis RNA therapies RNA therapy rods RPE65 splicing modulation spontaneous nonsense correction Stargardt disease T nonsense mutation therapy translational translational medicine treatment unfolded protein response Usher syndrome |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674051103321 |
Collin Rob W.J
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Lo trovi qui: Univ. Federico II | ||
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